Citation Impact
Citing Papers
Rubinstein-Taybi syndrome caused by mutations in the transcriptional co-activator CBP
1995 StandoutNature
Hallmarks of Cancer: The Next Generation
2011 Standout
The DNA-damage response in human biology and disease
2009 StandoutNature
Regulation and mechanisms of gene amplification
1995
Regulation of p53 stability by Mdm2
1997 StandoutNature
WAF1, a potential mediator of p53 tumor suppression
1993 Standout
Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells
1992 StandoutNobel
Telomerase Mutations in Families with Idiopathic Pulmonary Fibrosis
2007 StandoutNobel
Crystal structure of parallel quadruplexes from human telomeric DNA
2002 StandoutNature
Growth factors and oncogenes in breast cancer
1990
p53, the Cellular Gatekeeper for Growth and Division
1997 Standout
A DNA-fuelled molecular machine made of DNA
2000 StandoutNature
The Role of the p53 Tumor Suppressor Gene in Squamous Cell Carcinoma of the Head and Neck
1993
Telomere maintenance mechanisms as a target for drug development
2000
Unrepaired DNA Breaks in p53-Deficient Cells Lead to Oncogenic Gene Amplification Subsequent to Translocations
2002
Determinants in mammalian telomerase RNA that mediate enzyme processivity and cross-species incompatibility
2003
BRAFE600-associated senescence-like cell cycle arrest of human naevi
2005 StandoutNature
Genetic instabilities in human cancers
1998 StandoutNature
Telomeres and telomerase in cancer
2009
When Checkpoints Fail
1997 StandoutNobel
AID Is Required for c-myc/IgH Chromosome Translocations In Vivo
2004 StandoutNobel
Natural and pharmacological regulation of telomerase
2002
Aplysia CREB2 represses long-term facilitation: Relief of repression converts transient facilitation into long-term functional and structural change
1995 StandoutNobel
Human telomerase contains two cooperating telomerase RNA molecules
2001
The evolution of the amplified adenylate deaminase 2 domains in Chinese hamster cells suggests the sequential operation of different mechanisms of DNA amplification
1992
DNA-templated assembly and electrode attachment of a conducting silver wire
1998 StandoutNature
Human Telomerase RNA Template Sequence Is a Determinant of Telomere Repeat Extension Rate
2005
High-Resolution Chromosome 3p Allelotyping of Breast Carcinomas and Precursor Lesions Demonstrates Frequent Loss of Heterozygosity and a Discontinuous Pattern of Allele Loss
2001
Induction of gene amplification by 5-aza-2′-deoxycytidine
1992
Genetic instability in colorectal cancers
1997 StandoutNature
Amplification of cellular oncogenes: A predictor of clinical outcome in human cancer
1990
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Switching and Signaling at the Telomere
2001 StandoutNobel
Regulation and Mechanisms of Mammalian Gene Amplification
1993
p53 is required for radiation-induced apoptosis in mouse thymocytes
1993 StandoutNature
Quantitative in situ evaluation of telomeres in fluorescence in situ hybridization-processed sections of cutaneous melanocytic lesions and correlation with telomerase activity
2002
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
A G-Quadruplex-Interactive Potent Small-Molecule Inhibitor of Telomerase Exhibiting in Vitro and in Vivo Antitumor Activity
2002
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
2005 StandoutNature
Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles
1992
Molecular biology of double‐minute chromosomes
1993
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
A universal telomerase RNA core structure includes structured motifs required for binding the telomerase reverse transcriptase protein
2004 StandoutNobel
Comparative Genomic Hybridization for Molecular Cytogenetic Analysis of Solid Tumors
1992 StandoutScience
Telomerase core components protect Candida telomeres from aberrant overhang accumulation
2007 StandoutNobel
Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations
1994 StandoutScience
Cachectin and tumour necrosis factor as two sides of the same biological coin
1986 StandoutNatureNobel
DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts.
1994
Selective Interactions of Cationic Porphyrins with G-Quadruplex Structures
2001
Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands
2002
Induction of murine interleukin 1: stimuli and responsive primary cells.
1987 StandoutNobel
Cancer Cell Cycles
1996 StandoutScience
Life with 6000 Genes
1996 StandoutScience
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Co-amplified markers alternate in megabase long chromosomal inverted repeats and cluster independently in interphase nuclei at early steps of mammalian gene amplification.
1992
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage.
1996
FJ5002: a potent telomerase inhibitor identified by exploiting the disease-oriented screening program with COMPARE analysis.
1999
Fever: The Old and the New
1984
Connecting Chromosomes, Crisis, and Cancer
2002 Science
The Structure and Function of Telomerase Reverse Transcriptase
2006
Stretching of a Single Tethered Polymer in a Uniform Flow
1995 StandoutScienceNobel
The human Ha-ras oncogene induces genomic instability in murine fibroblasts within one cell cycle.
1994
Dynamic Molecular Combing: Stretching the Whole Human Genome for High-Resolution Studies
1997 Science
Optical trapping and manipulation of neutral particles using lasers
1997 StandoutNobel
Stretching DNA with a Receding Meniscus: Experiments and Models
1995
Functional analysis of the pseudoknot structure in human telomerase RNA
2005 StandoutNobel
A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation
2001 StandoutNobel
Haploinsufficiency of t e lomerase reverse transcriptase leads to anticipation in autosomal dominant dyskeratosis congenita
2005 StandoutNobel
A Cell Culture Model for T Lymphocyte Clonal Anergy
1990 StandoutScience
Knotted Fishing Line, Covalent Bonds, and Breaking Points
1999 StandoutScienceNobel
Interleukin-1 Stimulates the Secretion of Hypothalamic Corticotropin-Releasing Factor
1987 StandoutScience
High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6
2001 StandoutNobel
G-quadruplex DNA: A target for drug design
1998
Stimulation of Muscle Protein Degradation and Prostaglandin E2Release by Leukocytic Pyrogen (Interleukin-1)
1983
Overstretching B-DNA: The Elastic Response of Individual Double-Stranded and Single-Stranded DNA Molecules
1996 StandoutScience
Interleukin 1: An Immunological Perspective
1985
Control of Angiogenesis in Fibroblasts by p53 Regulation of Thrombospondin-1
1994 StandoutScience
Activation of the Estrogen Receptor Through Phosphorylation by Mitogen-Activated Protein Kinase
1995 StandoutScience
Sister chromatid fusion initiates amplification of the dihydrofolate reductase gene in Chinese hamster cells.
1993
Inefficient growth arrest in response to dNTP starvation stimulates gene amplification through bridge-breakage-fusion cycles.
1996
Fluorescence Spectroscopy of Single Biomolecules
1999 StandoutScience
Alignment and Sensitive Detection of DNA by a Moving Interface
1994 Science
Gene Amplification in a p53-Deficient Cell Line Requires Cell Cycle Progression under Conditions That Generate DNA Breakage
1998
Cell Cycle Checkpoints: Preventing an Identity Crisis
1996 StandoutScience
Works of B E Windle being referenced
A human breast cancer model for the study of telomerase inhibitors based on a new biotinylated-primer extension assay
1999
Preclinical and clinical strategies for development of telomerase and telomere inhibitors
1997
High resolution visual mapping of stretched DNA by fluorescent hybridization
1993
Molecular dissection of mammalian gene amplification: New mechanistic insights revealed by analyses of very early events
1992
A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration.
1991
Failure of rabbit neutrophils to secrete endogenous pyrogen when stimulated with staphylococci.
1980
Heterogeneity of rabbit endogenous pyrogens is not attributable to glycosylated variants of a single polypeptide chain
1981
Rabbit macrophages secrete two biochemically and immunologically distinct endogenous pyrogens
1981
Effects of cationic porphyrins as G-quadruplex interactive agents in human tumor cells.
1999
Effect of dGTP Concentration on Human and CHO Telomerase
1999
Amplified human MYC oncogenes localized to replicating submicroscopic circular DNA molecules.
1988