Citation Impact
Citing Papers
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
Serotonin Transporter Genetic Variation and the Response of the Human Amygdala
2002 StandoutScience
World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Unipolar Depressive Disorders, Part 1: Acute and Continuation Treatment of Major Depressive Disorder
2002
Reboxetine, a New Noradrenaline Selective Antidepressant, Is at Least as Effective as Fluoxetine in the Treatment of Depression
2002
Depression
2018 Standout
From stress to inflammation and major depressive disorder: A social signal transduction theory of depression.
2014 Standout
Functional polymorphism in the serotonin transporter promoter at the SLC6A4 locus and mood disorders
1998
Switching Antidepressants After a First Selective Serotonin Reuptake Inhibitor in Major Depressive Disorder
2006
Cytokines and major depression
2005
No health without mental health
2007 Standout
Prior Exposure to THC Increases the Addictive Effects of Nicotine in Rats
2013
The Corticosteroid Receptor Hypothesis of Depression
2000 Standout
Physiological and behavioural responsivity to stress and anxiogenic stimuli in COMT-deficient mice
2011
Cytokines, “Depression Due to A General Medical Condition,” and Antidepressant Drugs
1999
The inflammasome: Pathways linking psychological stress, depression, and systemic illnesses
2012
Mechanisms and Functional Implications of Adult Neurogenesis
2008 Standout
Anxiolytic-like profile of mirtazapine in rat conditioned fear stress model: Functional significance of 5-hydroxytryptamine 1A receptor and α1-adrenergic receptor
2009
Adverse Health Effects of Marijuana Use
2014 Standout
Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice
1999 StandoutNobel
Efficacy and Tolerability of Reboxetine Compared with Citalopram
2006
Pharmacological Profile of the 5‐HT2C Receptor Agonist WAY‐163909; Therapeutic Potential in Multiple Indications
2006
Nitric oxide synthase inhibitors in experimental ischemic stroke and their effects on infarct size and cerebral blood flow: A systematic review
2005
Chronic inflammation in the etiology of disease across the life span
2019 Standout
TNFα Signaling in Depression and Anxiety: Behavioral Consequences of Individual Receptor Targeting
2006
Mechanism of triazolo-benzodiazepine and benzodiazepine action in anxiety and depression: Behavioral studies with concomitant in vivo CA1 hippocampal norepinephrine and serotonin release detection in the behaving animal
1998
Physiology and Neurobiology of Stress and Adaptation: Central Role of the Brain
2007 Standout
Psychosomatic Aspects of Cushing’s Disease
1998
Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a role in the pathophysiology of unipolar depression
2011
Cushing's syndrome
2015 Standout
The Concept of Depression as a Dysfunction of the Immune System
2010
The Flinders Sensitive Line rat: A selectively bred putative animal model of depression
2005
Depression following pegylated interferon-alpha: Characteristics and vulnerability
2007
Neural and developmental actions of lithium: A unifying hypothesis
1989 Standout
Immune modulation of learning, memory, neural plasticity and neurogenesis
2010
Acute Antidepressant-Like and Antianxiety-Like Effects of Tryptophan in Mice
2001
Effect of the GABA-transaminase inhibitor vigabatrin on exploratory behaviour in socially isolated rats
1995
Dysregulated relationship of inflammation and oxidative stress in major depression
2012
The Pharmacology and Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”)
2003 Standout
Chronic treatment with the atypical antidepressant tianeptine attenuates sickness behavior induced by peripheral but not central lipopolysaccharide and interleukin-1β in the rat
2001
Assessing antidepressant activity in rodents: recent developments and future needs
2002
Effects of antidepressants and benzodiazepine treatments on the dendritic structure of CA3 pyramidal neurons after chronic stress
1999
Roles of nitric oxide in brain hypoxia-ischemia
1999
Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis
2015 Standout
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Improvement by nefiracetam of β‐amyloid‐(1‐42)‐induced learning and memory impairments in rats
1999
Inflammation and depression: a causal or coincidental link to the pathophysiology?
2017
Neuroprotective effects of FeTMPyP: A peroxynitrite decomposition catalyst in global cerebral ischemia model in gerbils
2006
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review
2003 Standout
Sex and gender: modifiers of health, disease, and medicine
2020 Standout
Mechanism of Action of St John???s Wort in Depression
2003
Novelty and Anxiolytic Drugs Dissociate Two Components of Hippocampal Theta in Behaving Rats
2013 StandoutNobel
Altered dendritic spine density in animal models of depression and in response to antidepressant treatment
2001
Elevated platelet factor 4 and β-thromboglobulin plasma levels in depressed patients with ischemic heart disease
1997
Neurohormonal and inflammatory hyper-responsiveness to acute mental stress in depression☆
2010
The Serotonin Syndrome
2005 Standout
Effects of doxycycline on depressive-like behavior in mice after lipopolysaccharide (LPS) administration
2013
The Neurosteroids DHEA and DHEAS May Influence Cognitive Performance by Altering Affective State
1999
Role of brain IL-1β on fatigue after exercise-induced muscle damage
2006
Fluvoxamine versus fluoxetine in major depressive episode: a double‐blind randomised comparison
2003
Interleukin-6-(IL-6) plasma levels in depression and schizophrenia: comparison between the acute state and after remission
1997
Potent serotonin (5-HT)2A receptor antagonists completely prevent the development of hyperthermia in an animal model of the 5-HT syndrome
2001
Cytokines, stress, and depressive illness
2002
Acute 3,4-methylenedioxymethamphetamine (MDMA) administration produces a rapid and sustained suppression of immune function in the rat
1998
Cytokines, stressors, and clinical depression: Augmented adaptation responses underlie depression pathogenesis
2005
Cholinergic/Serotonergic Interactions in Hypothermia: Implications for Rat Models of Depression
1998
Comparison of the effectiveness of reboxetine versus fluoxetine in patients with atypical depression: A single-blind, randomized clinical trial
2006
Acute Toxicity of 3,4-Methylenedioxymethamphetamine (MDMA) in Sprague–Dawley and Dark Agouti Rats
1999
Early kynurenine pathway activation following cardiac arrest in rats, pigs, and humans
2013
Cytokines as mediators of depression: What can we learn from animal studies?
2005
Sex differences in antidepressant efficacy
2018
Neurobiology of Depression
2002 Standout
Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis
2009 Standout
Eating ourselves to death (and despair): The contribution of adiposity and inflammation to depression
2010
The Relationship of Depression and Stressors to Immunological Assays: A Meta-Analytic Review
2001
Major Depressive Disorder
2008 Standout
Major Depression and Activation of The Inflammatory Response System
1999
Behavioral Effects of Chronic Fluoxetine in BALB/cJ Mice Do Not Require Adult Hippocampal Neurogenesis or the Serotonin 1A Receptor
2007
Effect of Duloxetine on Pain, Function, and Quality of Life Among Patients With Chemotherapy-Induced Painful Peripheral Neuropathy
2013 Standout
Neuroprotective and anti-amnesic potentials of sigma (σ) receptor ligands
1997
Serotonin, tryptophan metabolism and the brain-gut-microbiome axis
2014 Standout
Clustering of Depression and Inflammation in Adolescents Previously Exposed to Childhood Adversity
2012
Inflammation-associated depression: From serotonin to kynurenine
2010
Psychological aspects of endocrine disease
1998
Cocaine and Other Stimulants
1988 Standout
GABAergic dysfunction in mood disorders
2003
A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness
2010 Standout
Alzheimer's Disease
2004 Standout
Behavioral effects of phenelzine in an experimental model for screening anxiolytic and anti-panic drugs: correlation with changes in monoamine–oxidase activity and monoamine levels
1998
Acute-Phase Proteins and Other Systemic Responses to Inflammation
1999 Standout
From inflammation to sickness and depression: when the immune system subjugates the brain
2007 Standout
Timing and Specificity of the Cognitive Changes Induced by Interleukin-2 and Interferon-α Treatments in Cancer Patients
2001
The molecular neurobiology of depression
2008 StandoutNature
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
Clinically Significant Drug Interactions with Newer Antidepressants
2011
Acute phase proteins in schizophrenia, mania and major depression: modulation by psychotropic drugs
1997
Animal Models of Depression: Utility for Transgenic Research
2000
Parkinson's Disease
2003 Standout
The role of inflammation in depression: from evolutionary imperative to modern treatment target
2015 Standout
Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival
2007 Standout
Vasopressin maintenance of ethanol tolerance requires intact brain noradrenergic systems
1983
Vitamin E and Donepezil for the Treatment of Mild Cognitive Impairment
2005 Standout
A review of the biochemical and neuropharmacological actions of lithium
1987
Applications of the Morris water maze in the study of learning and memory
2001 Standout
Neurogenetic Adaptive Mechanisms in Alcoholism
1987 StandoutScience
Facilitation of memory consolidation by vasopressin: Mediation by terminals of the dorsal noradrenergic bundle?
1979
Pharmacological Approaches for the Treatment of Obesity
2002
Pharmacological interventions for somatoform disorders in adults
2014 Standout
Marine Indole Alkaloids: Potential New Drug Leads for the Control of Depression and Anxiety
2010 Standout
Synthesis and structure-activity relationships of novel 2-amino alkyl chromones and related derivatives as a site-selective ligands
1998
Melancholic microbes: a link between gut microbiota and depression?
2013
Chromone: A Valid Scaffold in Medicinal Chemistry
2014 Standout
A 24-week, double-blind, placebo-controlled trial of donepezil in patients with Alzheimer's disease
1998
Long-term amphetamine treatment attenuates or reverses the depression of neuronal activity produced by dopamine agonists in the ventral tegmental area
1984
ProTox-II: a webserver for the prediction of toxicity of chemicals
2018 Standout
Impact of Psychological Factors on the Pathogenesis of Cardiovascular Disease and Implications for Therapy
1999 Standout
Biological and Phytochemical Screening of Plants
1966 Standout
3,4-methylenedioxymethamphetamine (MDMA; Ecstasy) administration produces dose-dependent neurochemical, endocrine and immune changes in the rat
1999
Effects of Chronic D-Amphetamine and Phenylethylamine on the Concentrations of Neurotransmitter Amino Acids in the Rat Brain
1983
Passiflora: a review update
2004 Standout
Chronic amphetamine: Is dopamine a link in or a mediator of the development of tolerance and reverse tolerance?
1981
Effect of 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine (MPTP) on monoamine neurotransmitters in mouse brain & heart
1984
Pharmacodynamic and receptor binding changes during chronic lorazepam administration
2001
Increased serum soluble CD8 or suppressor/cytotoxic antigen concentrations in depression: Suppressive effects of glucocorticoids
1996
α2-adrenoreceptors on human platelets: Selective labelling by [3H]clonidine and [3H]yohimbine and competetive inhibition by antidepressant drugs
1981
Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants
2003 StandoutScience
Two dissociable components of behavioral sensitization following repeated amphetamine administration
1982
Apparent tolerance to some aspects of amphetamine stereotypy with long-term treatment
1980
Receptor Sensitivity and the Mechanism of Action of Antidepressant Treatment
1981
Enduring changes in brain and behavior produced by chronic amphetamine administration: A review and evaluation of animal models of amphetamine psychosis
1986 Standout
Chitosan Chemistry and Pharmaceutical Perspectives
2004 Standout
The immunoregulatory effects of antidepressants
2001
Behavioural tolerance to amphetamine and other psychostimulants: The case for considering behavioural mechanisms
1983
Biocatalytic Synthesis of Chiral Alcohols and Amino Acids for Development of Pharmaceuticals
2013
Affinity chromatography of human platelet α 2 -adrenergic receptors
1982 StandoutNobel
Enduring changes in brain and behavior produced by chronic amphetamine administration: A review and evaluation of animal models of amphetamine psychosis
1986 Standout
Works of B. E. Leonard being referenced
Anatomical, Physiological, and Behavioral Aspects of Olfactory Bulbectomy in The Rat
1981
Catalase, Superoxide Dismutase and Glutathione Peroxidase Activity in Neutrophils of Sham-Operated and Olfactory-Bulbectomised Rats following Chronic Treatment with Desipramine and Lithium Chloride
1994
An Appraisal of the Pharmacological and Toxicological Effects of a Single Oral Administration of 3,4‐Methylenedioxymethamphetamine (MDMA) in the Rat
1997
An assessment of the effects of central interleukin-1β, -2, -6, and tumor necrosis factor-α administration on some behavioural, neurochemical, endocrine and immune parameters in the rat
1998
Metyrapone displays antidepressant-like properties in preclinical paradigms
1999
NG-nitro-l-arginine methyl ester protects against lipid peroxidation in the gerbil following cerebral ischaemia
1995
Abnormal zymosan-induced neutrophil chemiluminescence as a marker of depression
1990
The olfactory bulbectomized rat as a model of depression: An update
1997
Serotonin receptors-where are they going?
1994
A double-blind, placebo-controlled, efficacy, safety, and pharmacokinetic study of INN 00835, a novel antidepressant peptide, in the treatment of major depression
2000
Effects of acute and chronic administration of selective monoamine re-uptake inhibitors in the rat forced swim test
2003
The effect of 2-amino-3-phosphonopropionic acid (AP-3) in the gerbil model of cerebral ischaemia
1995
Phencyclidine prevents spatial navigation and passive avoidance deficits in ibotenate lesioned rats
1994
Effect of Chronic Treatment with Piracetam and Tacrine on Some Changes Caused by Thymectomy in the Rat Brain
1997
Drugs Acting on σ and Phencyclidine Receptors
1989
Effects of psychotropic drugs on the behavior and neurochemistry of olfactory bulbectomized rats
1990
β-Amyloid(Phe(SO3H)24)25–35 in rat nucleus basalis induces behavioral dysfunctions, impairs learning and memory and disrupts cortical cholinergic innervation
1998
Pharmacological Differences of Serotonin Reuptake Inhibitors and Possible Clinical Relevance
1992
Stress, Depression, and The Role of Cytokines
1999
Noradrenaline in basic models of depression
1997
The σ receptor ligand JO 1784 (igmesine hydrochloride) is neuroprotective in the gerbil model of global cerebral ischaemia
1995
The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression
2010
Changes in immunoglobulin, complement and acute phase protein levels in the depressed patients and normal controls
1994
The Comparison of Changes in Behavior, Neurochemistry, Endocrine, and Immune Functions after Different Routes, Doses and Durations of Administrations of IL-1β in Rats
2006
Ethyl-eicosapentaenoic acid ingestion prevents corticosterone-mediated memory impairment induced by central administration of interleukin-1β in rats
2003
Alteration by a plasma factor of platelet aggregation and 5HT uptake in depression
1992
The HPA and immune axes in stress: the involvement of the serotonergic system
2005
Serotonin Receptors and Their Function in Sleep, Anxiety Disorders and Depression
1996
Neuropharmacology of antidepressants that modify central noradrenergic and serotonergic function: a short review
1999
Monoamine-related markers of depression: Changes following treatment
1982
The effects of chronic lithium chloride administration on some behavioural and immunological changes in the bilaterally olfactory bulbectomized rat
1994
The effect of testosterone and cyproterone acetate on the concentration of γ-aminobutyric acid in brain areas of aggressive and non-aggressive mice
1977
Some effects of a new tetracyclic anti-depressant compound, Org GB 94, on the metabolism of monoamines in the rat brain
1974
The effect of olfactory bulbectomy in the rat, alone or in combination with antidepressants and endogenous factors, on immune function
1995
The acute effects of amphetamine, chlorpromazine, amitriptyline and lithium on adenosine 5-triphosphatase activity in the cortex of the rat brain
1978
Effect of chronic administration of the 6-aza analogue of mianserin (Org. 3770) and its enantiomers on behaviour and changes in noradrenaline metabolism of olfactory-bulbectomized rats in the “open field” apparatus
1986
Isolation and assay of noradrenaline, dopamine, 5-hydroxy-tryptamine, and several metabolites from brain tissue using disposable bio-rad columns packed with sephadex G-10
1978
The comparative pharmacology of new antidepressants.
1993
Effect of chronic amphetamine administration on the behaviour of rats in the open field apparatus: reversal of post-withdrawal depression by two antidepressants
1978
Autoradiographic distribution of cholinergic muscarinic receptors and serotonin2 receptors in olfactory bulbectomized (OB) rats after chronic treatment with mianserin and desipramine
1994
Pharmacological properties of some West Indian medicinal plants
1965
Comparative effects of serotonergic agonists withvarying efficacy at the 5-HT1Areceptor on core body temperature: modification by the selective 5-HT1Areceptor antagonist WAY 100635
1999
Mechanisms of Action of Antidepressants
1995
Parallel changes in behaviour and hippocampal serotonin metabolism in rats following treatment with desglycinamide lysine vasopressin
1977
New antidepressants and the biology of depression
1985
Chronic effects of miaserin on noradrenaline metabolism in the rat brain: Evidence for a pre-synaptic ?-adrenolytic action in vivo
1979
The effects of the 5-HT1A agonist flesinoxan, in three paradigms for assessing antidepressant potential in the rat
1997
The effects of strain differences and emotional status of rats on the behavioural and neurochemical effects of chronic treatment with apomorphine
1980
Changes in brain γ-aminobutyric acid concentrations following acute and chronic amphetamine administration and during post amphetamine depression
1978
Antidepressant properties of the triazolobenzodiazepines alprazolam and adinazolam: studies on the olfactory bulbectomized rat model of depression.
1985
A comparison of the acute and chronic effects of four antidepressant drugs on the turnover of serotonin, dopamine and noradrenaline in the rat brain
1976
The acute and chronic effects of D-amphetamine, chlorpromazine, amitriptyline and lithium chloride on adenosine 5-triphosphatases in different regions of the rat brain
1978
The effect of stressful behavioural exposure on endocrine and immune parameters in the rat
1994
Role of paroxetine in interferon-α-induced immune and behavioural changes in male Wistar rats
2007
Commentary on the mode of action of benzodiazepines
1993
The effect of chronic administration of d‐amphetamine on regional changes in catecholamines in the rat brain
1977
Animal Models of Drug Addiction (Neuromethods 24)
1993