Standout Papers
Citation Impact
Citing Papers
Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells
2008 StandoutScienceNobel
Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution
2009 StandoutScienceNobel
Differentiation of muscle, fat, cartilage, and bone from progenitor cells present in a bone-derived clonal cell population: effect of dexamethasone.
1988
A Genomewide Search for Ribozymes Reveals an HDV-Like Sequence in the Human CPEB3 Gene
2006 StandoutScienceNobel
The Serine Protease TMPRSS6 Is Required to Sense Iron Deficiency
2008 StandoutScienceNobel
Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD
1989
Direct conversion of fibroblasts to functional neurons by defined factors
2010 StandoutNatureNobel
Induction of human neuronal cells by defined transcription factors
2011 StandoutNatureNobel
CeMyoD accumulation defines the body wall muscle cell fate during C. elegans embryogenesis
1990 StandoutNobel
Inflammation and cancer
2002 StandoutNature
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
2013 StandoutNatureNobel
Elevated levels of circulating cachectin/tumor necrosis factor in patients with acquired immunodeficiency syndrome
1988
EVIDENCE FOR TUMOUR NECROSIS FACTOR/CACHECTIN PRODUCTION IN CANCER
1987
The history, properties, and biological effects of cachectin
1988 StandoutNobel
Physiological Responses to Cachectin
2007
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
Cachectin: A Hormone that Triggers Acute Shock and Chronic Cachexia
1988
Expression of a single transfected cDNA converts fibroblasts to myoblasts
1987 Standout
A Xenopus mRNA related to Drosophila twist is expressed in response to induction in the mesoderm and the neural crest
1989 StandoutNobel
The generation of diversity and pattern in animal development
1992 StandoutNobel
Elevated Circulating Levels of Tumor Necrosis Factor in Severe Chronic Heart Failure
1990 Standout
The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product
1990 StandoutNobel
Activation of muscle genes without myogenesis by ectopic expression of MyoD in frog embryo cells
1990 StandoutNatureNobel
Neutrophils Express Tumor Necrosis Factor-α During Mouse Skin Wound Healing
1995
Tumor necrosis factor expression in human epithelial tumor cell lines.
1988
University of California/Davis Interdepartmental Conference on Gram-Negative Septicemia
1991 StandoutNobel
The Drosophila gene tailless is expressed at the embryonic termini and is a member of the steroid receptor superfamily
1990 StandoutNobel
Metabolic effects of cachectin/tumor necrosis factor are modified by site of production. Cachectin/tumor necrosis factor-secreting tumor in skeletal muscle induces chronic cachexia, while implantation in brain induces predominantly acute anorexia.
1990
Dexamethasone induction of osteoblast mRNAs in rat marrow stromal cell cultures
1991
Mechanisms of fatty acid-induced inhibition of glucose uptake.
1994 Standout
C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia
1994 StandoutNobel
Steroid-Induced Adipogenesis in a Pluripotential Cell Line from Bone Marrow*
1997
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Tumor necrosis factor-induced reversal of adipocytic phenotype of 3T3-L1 cells is preceded by a loss of nuclear CCAAT/enhancer binding protein (C/EBP).
1992
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
Local and Systemic Effects of Intradermal Recombinant Interferon-γ in Patients with Lepromatous Leprosy
1986 StandoutNobel
The Structure of Tumor Necrosis Factor-α at 2.6 Å Resolution
1989
Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.
1986 StandoutNobel
Control of Cachectin (Tumor Necrosis Factor) Synthesis: Mechanisms of Endotoxin Resistance
1986 StandoutScienceNobel
Multilineage Potential of Adult Human Mesenchymal Stem Cells
1999 StandoutScience
Genetic Control of Differentiation of the Caenorhabditis elegans Touch Receptor Neurons
1989 StandoutScienceNobel
The structure of tumor necrosis factor-alpha at 2.6 A resolution. Implications for receptor binding.
1989
Effect of endotoxin-induced monokines on glucose metabolism in the muscle cell line L6.
1987
Identity of differentiation inducing factor and tumour necrosis factor
1986 Nature
Tumor necrosis factor alpha inhibits signaling from the insulin receptor.
1994
Primary structure and expression of a functional human glucocorticoid receptor cDNA
1985 StandoutNature
Cachectin and tumour necrosis factor as two sides of the same biological coin
1986 StandoutNatureNobel
Cachectin/tumor necrosis factor regulates hepatic acute-phase gene expression.
1986
Recombinant human tumor necrosis factor increases mRNA levels and surface expression of HLA-A,B antigens in vascular endothelial cells and dermal fibroblasts in vitro.
1986
Cachectin/tumor necrosis factor induces cachexia, anemia, and inflammation.
1988 StandoutNobel
Characterization of a steroid hormone receptor gene and mRNA in wild-type and mutant cells
1984 Nature
Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors
2008 StandoutScienceNobel
Severely Impaired Adipsin Expression in Genetic and Acquired Obesity
1987 Science
Tumor necrosis factor-alpha stimulates hepatic lipogenesis in the rat in vivo.
1987
Species specificity of human and murine tumor necrosis factor. A comparative study of tumor necrosis factor receptors.
1986
Shock and Tissue Injury Induced by Recombinant Human Cachectin
1986 StandoutScienceNobel
Tumor necrosis factor can induce fever in rats without activating protein breakdown in muscle or lipolysis in adipose tissue.
1988
Induction of β2-interferon by tumor necrosis factor: A homeostatic mechanism in the control of cell proliferation
1986
Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.
1987 Standout
Plasticity of the Differentiated State
1985 Science
Passive Immunization Against Cachectin/Tumor Necrosis Factor Protects Mice from Lethal Effect of Endotoxin
1985 StandoutScienceNobel
The human β-interferon gene enhancer is under negative control
1986
Tumor necrosis factor and lymphotoxin induce differentiation of human myeloid cell lines in synergy with immune interferon.
1986
A direct role for C/EBP and the AP-I-binding site in gene expression linked to adipocyte differentiation.
1989
Nucleoprotein complexes that regulate gene expression in adipocyte differentiation: direct participation of c-fos
1987
ASSOCIATION BETWEEN TUMOUR NECROSIS FACTOR IN SERUM AND FATAL OUTCOME IN PATIENTS WITH MENINGOCOCCAL DISEASE
1987
Cachectin: More Than a Tumor Necrosis Factor
1987 StandoutNobel
Interferons and tumor necrosis factors have similar catabolic effects on 3T3 L1 cells.
1986
Regulated expression of human growth hormone genes in mouse cells
1982 StandoutNobel
Nucleotide sequence and hormonal regulation of mouse glycerophosphate dehydrogenase mRNA during adipocyte and muscle cell differentiation.
1987
Transcriptional repression of the GLUT4 and C/EBP genes in 3T3-L1 adipocytes by tumor necrosis factor-alpha.
1991
Immunochemical analysis of the glucocorticoid receptor: identification of a third domain separate from the steroid-binding and DNA-binding domains.
1982
Adipsin and Complement Factor D Activity: An Immune-Related Defect in Obesity
1989 Science
Characterization of the purified activated glucocorticoid receptor from rat liver cytosol.
1984
42 bp element from LDL receptor gene confers end-product repression by sterols when inserted into viral TK promoter
1987 StandoutNobel
Adipsin: A Circulating Serine Protease Homolog Secreted by Adipose Tissue and Sciatic Nerve
1987 Science
Sequence-specific binding of glucocorticoid receptor to MTV DNA at sites within and upstream of the transcribed region
1983
Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1.
1986
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance
1993 StandoutScience
Recombinant Human Tumor Necrosis Factor-α: Effects on Proliferation of Normal and Transformed Cells in Vitro
1985 StandoutScience
Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors
1986 Nature
Tumour necrosis factors α and β inhibit virus replication and synergize with interferons
1986 Nature
B Lineage—Specific Interactions of an Immunoglobulin Enhancer with Cellular Factors in Vivo
1985 StandoutScienceNobel
Prostaglandin E2 regulates macrophage-derived tumor necrosis factor gene expression.
1988
RAISED SERUM LEVELS OF TUMOUR NECROSIS FACTOR IN PARASITIC INFECTIONS
1986
The growth factor-like effects of tumor necrosis factor-alpha. Stimulation of glucose transport activity and induction of glucose transporter and immediate early gene expression in 3T3-L1 preadipocytes
1990
Tumor necrosis factor enhances eosinophil toxicity to Schistosoma mansoni larvae.
1986
Induction of tumor necrosis factor expression and resistance in a human breast tumor cell line.
1987
Identification of MRF4: a new member of the muscle regulatory factor gene family.
1989
Regulation of lipoprotein lipase synthesis by recombinant tumor necrosis factor—The primary regulatory role of the hormone in 3T3-L1 adipocytes
1986
Secretory products of macrophages.
1987 Standout
Raised serum levels of cachectin/tumor necrosis factor alpha in renal allograft rejection.
1987
A developmentally regulated mRNA from 3T3 adipocytes encodes a novel serine protease homologue.
1985
Recombinant human tumor necrosis factor does not inhibit lipoprotein lipase in primary cultures of isolated human adipocytes
1988
Regulation of adipocyte gene expression in differentiation and syndromes of obesity/diabetes.
1993
Effects of recombinant tumor necrosis factor on proliferation and differentiation of leukemic and normal hemopoietic cells in vitro. Relationship to cell surface receptor.
1986
Effect of tumor necrosis factor administration in vivo on lipoprotein lipase activity in various tissues of the rat.
1989
Characterization of wild type and mutant glucocorticoid receptors from rat hepatoma and mouse lymphoma cells.
1985
Tumor necrosis factor type alpha stimulates human endothelial cells to produce granulocyte/macrophage colony-stimulating factor.
1986
Mammary tumor virus DNA contains sequences required for its hormone-regulated transcription
1981
Cachectin/tumor necrosis factor stimulates collagenase and prostaglandin E2 production by human synovial cells and dermal fibroblasts.
1985 StandoutNobel
Early events in the stimulation of mammary tumor virus RNA synthesis by glucocorticoids. Novel assays of transcription rates.
1984
Efficient selection for high-expression transfectants with a novel eukaryotic vector
1991 Standout
Tumor necrosis factor provokes superoxide anion generation from neutrophils
1986
Unraveling Function in the TNF Ligand and Receptor Families
1994 StandoutScienceNobel
Cachectin/tumor necrosis factor mediates changes of skeletal muscle plasma membrane potential.
1986 StandoutNobel
Works of B Dieckmann being referenced
Inducible Expression of Amplified Human Beta Interferon Genes in CHO Cells
1984
Analysis of gene expression during differentiation of adipogenic cells in culture and hormonal control of the developmental program.
1984
Inducible expression of amplified human beta interferon genes in CHO cells.
1984
Inhibition of protein synthesis stimulates the transcription of human beta-interferon genes in Chinese hamster ovary cells.
1984
A Macrophage Factor Inhibits Adipocyte Gene Expression: An in Vitro Model of Cachexia
1985 StandoutScienceNobel
Isolation of glucocorticoid-unresponsive rat hepatoma cells by fluorescence-activated cell sorting
1980