Citation Impact
Citing Papers
Computational protein design enables a novel one-carbon assimilation pathway
2015 StandoutNobel
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
2005 Standout
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction
2008 Standout
TOR Signaling in Growth and Metabolism
2006 Standout
Hallmarks of Cancer: The Next Generation
2011 Standout
FoxOs Enforce a Progression Checkpoint to Constrain mTORC1-Activated Renal Tumorigenesis
2010 StandoutNobel
Hypoxia — a key regulatory factor in tumour growth
2002 Standout
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Glucose-Independent Glutamine Metabolism via TCA Cycling for Proliferation and Survival in B Cells
2012
The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation
2011 Standout
MYC on the Path to Cancer
2012 Standout
Spaceflight and protein metabolism, with special reference to humans
1994
Ferroptosis as a p53-mediated activity during tumour suppression
2015 StandoutNature
Acetyl-coenzyme A synthetase (AMP forming)
2004
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
The Failing Heart — An Engine Out of Fuel
2007 Standout
The Biology of Cancer: Metabolic Reprogramming Fuels Cell Growth and Proliferation
2008 Standout
Cancer Cell Metabolism: Warburg and Beyond
2008 Standout
Impaired Mitochondrial Activity in the Insulin-Resistant Offspring of Patients with Type 2 Diabetes
2004 Standout
Proton‐translocating transhydrogenase and NAD‐ and NADP‐linked isocitrate dehydrogenases operate in a substrate cycle which contributes to fine regulation of the tricarboxylic acid cycle activity in mitochondria
1994
A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans
1999 StandoutNobel
Amino Acids Rather than Glucose Account for the Majority of Cell Mass in Proliferating Mammalian Cells
2016
Global pollinator declines: trends, impacts and drivers
2010 Standout
A Long Twentieth Century of the Cell Cycle and Beyond
2000 StandoutNobel
DNA sequence variation in a non-coding region of low recombination on the human X chromosome
1999 StandoutNobel
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
TLR4 links innate immunity and fatty acid–induced insulin resistance
2006 Standout
From Krebs to clinic: glutamine metabolism to cancer therapy
2016 Standout
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Life in extreme environments
2001 StandoutNature
Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
2014 StandoutNature
A Rice HAL2-like Gene Encodes a Ca2+-sensitive 3′(2′),5′-Diphosphonucleoside 3′(2′)-Phosphohydrolase and Complements Yeast met22 and Escherichia coli cysQ Mutations
1995
Regulation of cancer cell metabolism
2011 Standout
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
2015 Standout
HIF and c-Myc: Sibling Rivals for Control of Cancer Cell Metabolism and Proliferation
2007
Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
2013 Standout
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
Mechanisms of fatty acid-induced inhibition of glucose uptake.
1994 Standout
What We Talk About When We Talk About Fat
2014 Standout
Metabolic and cellular plasticity in white adipose tissue I: effects of β3-adrenergic receptor activation
2005
Resveratrol Improves Mitochondrial Function and Protects against Metabolic Disease by Activating SIRT1 and PGC-1α
2006 Standout
Autophagy: process and function
2007 Standout
Lethal Neonatal Multiorgan Deficiency of Carnitine Palmitoyltransferase II
1991
PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2
2016 StandoutNobel
Effect of triiodothyronine on mitochondrial energy coupling in human skeletal muscle
2001
Cellular and molecular diversities of mammalian skeletal muscle fibers
1990
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
2009 StandoutNature
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
Effect of elevated free fatty acids on glucose oxidation in normal humans
1988
Inhibition of glutaminase expression by antisense mRNA decreases growth and tumourigenicity of tumour cells
2000
Metabolic switching and fuel choice during T‐cell differentiation and memory development
2012
Oxidative damage and mitochondrial decay in aging.
1994 Standout
Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
2011 Standout
Role of glycerol 3-phosphate dehydrogenase in glyceride metabolism. Effect of diet on enzyme activities in chicken liver
1975
Rv2131c fromMycobacterium tuberculosisIs a CysQ 3′-Phosphoadenosine-5′-phosphatase
2008 StandoutNobel
How mitochondria produce reactive oxygen species
2008 Standout
Brown Adipose Tissue: Function and Physiological Significance
2004 Standout
Smoking and its effects on body weight and the systems of caloric regulation
1982
Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells
2007
Control of metabolism: What do we have to measure?
1987
GLUTAMINE METABOLISM IN LYMPHOCYTES: ITS BIOCHEMICAL, PHYSIOLOGICAL AND CLINICAL IMPORTANCE
1985
Intracellular Carbon Fluxes in Riboflavin-Producing Bacillus subtilis during Growth on Two-Carbon Substrate Mixtures
2002 StandoutNobel
Intermediary metabolism in the dauer larva of the nematode Caenorhabditis elegans— 1. Glycolysis, gluconeogenesis, oxidative phosphorylation and the tricarboxylic acid cycle
1989
Metabolism of [U‐13C]glucose in human brain tumors in vivo
2012
G 1 Events and Regulation of Cell Proliferation
1989 StandoutScience
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Interaction of carnitine with insulin-stimulated glucose metabolism in humans
1988
The regulation of extramitochondrial free calcium ion concentration by rat liver mitochondria
1978
Warm-Up Rates and Body Temperatures in Bees: The Importance of Body Size, Thermal Regime and Phylogeny
1989
Disorders of pyruvate carboxylase and the pyruvate dehydrogenase complex
1996
Cytosolic Ca2+ homeostasis in Ehrlich and Yoshida carcinomas. A new, membrane-permeant chelator of heavy metals reveals that these ascites tumor cell lines have normal cytosolic free Ca2+.
1985 StandoutNobel
The Physiological Role of Pyruvate Carboxylation in Hamster Brown Adipose Tissue
1979
Quantitative analysis of metabolic regulation. A graph-theoretic approach using spanning trees
1991 StandoutNobel
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy
2016 Standout
Free fatty acids increase basal hepatic glucose production and induce hepatic insulin resistance at different sites
2003
High Km glucose-phosphorylating (glucokinase) activities in a range of tumor cell lines and inhibition of rates of tumor growth by the specific enzyme inhibitor mannoheptulose.
1995
Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance
2003 StandoutScience
Bioenergetics in aging
1983
Molecules involved in proliferation of normal and cancer cells: presidential address.
1987
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Anhydrobiosis in Embryos of the Brine Shrimp Artemia: Characterization of Metabolic Arrest During Reductions in Cell-Associated Water
1988
Network Rigidity and Metabolic Engineering in Metabolite Overproduction
1991 Science
The Immunosuppressant Rapamycin Mimics a Starvation-Like Signal Distinct from Amino Acid and Glucose Deprivation
2002
Works of B. Crabtree being referenced
The activities of pyruvate carboxylase, phosphoenolpyruvate carboxylase and fructose diphosphatase in muscles from vertebrates and invertebrates
1972
Metabolic aspects of enzyme activity regulation.
1973
A systematic approach to describing and analysing metabolic control systems
1987
Modelling and quantifying metabolic control systems
1985
Substrate cycles in metabolic regulation and in heat generation.
1976
Evidence that the production of acetate in rat hepatocytes is a predominantly cytoplasmic process
1989
Sense and sensitivity
1985
A Quantitative Approach to Metabolic Control
1985
The role of high rates of glycolysis and glutamine utilization in rapidly dividing cells
1985
The activities of lipases and carnitine palmitoyl-transferase in muscles from vertebrates and invertebrates
1972
The activities of phosphorylase, hexokinase, phosphofructokinase, lactate dehydrogenase and the glycerol 3-phosphate dehydrogenase in muscles from vertebrates and invertebrates
1972
Flux-generating and regulatory steps in metabolic control
1981
Substrate cycles: their role in improving sensitivity in metabolic control
1984
The derivation and interpretation of control coefficients
1987