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Effect of Dexamethasone and Cyclosporin A on Allergen-induced Airway Hyperresponsiveness and Inflammatory Cell Responses in Sensitized Brown-Norway Rats
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Mediator and cytokine mechanisms in asthma.
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Nitric Oxide and Airway Disease
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Results of a Home-Based Environmental Intervention among Urban Children with Asthma
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Dendritic cells are associated with augmentation of antigen sensitization by influenza A virus infection in mice
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Effects of inhaled budesonide on allergen-induced airway responses and airway inflammation.
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Activated T-Lymphocytes and Macrophages in Bronchial Mucosa of Subjects with Chronic Bronchitis
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Mepolizumab and Exacerbations of Refractory Eosinophilic Asthma
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CD4 T-Lymphocyte Activation in Asthma Is Accompanied by Increased Serum Concentrations of Interleukin-5: Effect of Glucocorticoid Therapy
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Prednisone-dependent asthma: inflammatory indices in induced sputum
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Induction of nitric oxide synthase in asthma
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The role of female sex hormones in the development and severity of allergic and non‐allergic asthma
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Repeated daily exposure to 2 ppm nitrogen dioxide upregulates the expression of IL-5, IL-10, IL-13, and ICAM-1 in the bronchial epithelium of healthy human airways
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Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials
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Identification of T lymphocytes, Macrophages, and Activated Eosinophils in the Bronchial Mucosa in Intrinsic Asthma: Relationship to Symptoms and Bronchial Responsiveness
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High-affinity IgE receptor (FcepsilonRI)-bearing cells in bronchial biopsies from atopic and nonatopic asthma.
1996
Airway Mucosal Inflammation Even in Patients with Newly Diagnosed Asthma
1993
Eosinophilic and neutrophilic inflammation in asthma, chronic bronchitis, and chronic obstructive pulmonary disease
1993
Asthma: defining of the persistent adult phenotypes
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Review of the Molecular and Cellular Mechanisms of Action of Glucocorticoids for Use in Asthma
2002
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Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma.
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Salivary cortisol as a biomarker in stress research
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Interleukin-5 mRNA in Mucosal Bronchial Biopsies from Asthmatic Subjects
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2000
Glucocorticoids and the Th1/Th2 Balance
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Cyclosporine A inhibits airway reactivity and remodeling after chronic antigen challenge in cats.
1996
The development of allergic inflammation
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Inflammation and airway reactivity in asthma
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Airway epithelial cell expression of interleukin-6 in transgenic mice. Uncoupling of airway inflammation and bronchial hyperreactivity.
1994
Induction of corticosteroid insensitivity in human PBMCs by microbial superantigens
2000
Myofibroblast involvement in the allergen-induced late response in mild atopic asthma.
1997
Asthma
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The immunology of asthma
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Effect of Aerosolized Recombinant Human DNase on Exacerbations of Respiratory Symptoms and on Pulmonary Function in Patients with Cystic Fibrosis
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Activated T cells and eosinophilia in bronchoalveolar lavages from subjects with asthma correlated with disease severity
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Mepolizumab Treatment in Patients with Severe Eosinophilic Asthma
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Asthma phenotypes: the evolution from clinical to molecular approaches
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Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
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Activated T-lymphocytes and eosinophils in the bronchial mucosa in isocyanate-induced asthma
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Short-term efficacy of ultrasonically nebulized hypertonic saline in cystic fibrosis
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Phenotype of cells expressing mRNA for TH2-type (interleukin 4 and interleukin 5) and TH1-type (interleukin 2 and interferon gamma) cytokines in bronchoalveolar lavage and bronchial biopsies from atopic asthmatic and normal control subjects.
1995
The effects of glucocorticoids on human eosinophils
1994
Effects of steroid therapy on inflammatory cell subtypes in asthma
2009
Interleukin-4, -5, and -6 and tumor necrosis factor-alpha in normal and asthmatic airways: evidence for the human mast cell as a source of these cytokines.
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Intraepithelial Mast Cells in Allergic and Nonallergic Asthma: Assessment Using Bronchial Brushings
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Airway inflammation after removal from the causal agent in occupational asthma due to high and low molecular weight agents
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Outdoor air pollution and asthma
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Inflammation in bronchial biopsies of subjects with chronic bronchitis: inverse relationship of CD8+ T lymphocytes with FEV1.
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Peripheral blood CD4 but not CD8 t-lymphocytes in patients with exacerbation of asthma transcribe and translate messenger RNA encoding cytokines which prolong eosinophil survival in the context of a Th2-type pattern: effect of glucocorticoid therapy.
1995
The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease
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Increased sputum and bronchial biopsy IL-13 expression in severe asthma
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Eosinophils: Biology and Role in Disease
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Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
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Immunological Aspects of Allergic Asthma
1994
Inhibitory Effect of the TRFK-5 Anti-IL-5 Antibody in a Guinea Pig Model of Asthma
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Oligonucleotide therapy of allergic asthma☆☆☆
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Eosinophil recruitment to the lung in a murine model of allergic inflammation. The role of T cells, chemokines, and adhesion receptors.
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Expression of endothelial and leukocyte adhesion molecules intercellular adhesion molecule-1, E-selectin, and vascular cell adhesion molecule-1 in the bronchial mucosa in steady-state and allergen-induced asthma
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Modulation by interleukin-4 of cytokine release from mononuclear phagocytes in asthma
1994
Allergen exposure induces the activation of allergen‐specific Th2 cells in the airway mucosa of patients with allergic respiratory disorders
1993
Exploring the full spectrum of macrophage activation
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Analysis of induced sputum in adults with asthma: identification of subgroup with isolated sputum neutrophilia and poor response to inhaled corticosteroids
2002
The Structure of Large and Small Airways in Nonfatal and Fatal Asthma
1993
Increased interleukin-10 messenger RNA expression in atopic allergy and asthma.
1996
The potential role of tumour necrosis factor a in asthma
1993
T-helper Type 2–driven Inflammation Defines Major Subphenotypes of Asthma
2009
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsìveness, and the late asthmatic response
2000 Standout
Hypertonic Induction of Aquaporin-5 Expression through an ERK-dependent Pathway
2000 StandoutNobel
β-Arrestin-2 regulates the development of allergic asthma
2003 StandoutNobel
Predominant TH2-like Bronchoalveolar T-Lymphocyte Population in Atopic Asthma
1992 Standout
Relationships among numbers of bronchoalveolar lavage cells expressing messenger ribonucleic acid for cytokines, asthma symptoms, and airway methacholine responsiveness in atopic asthma
1993
Pathological features and inhaled corticosteroid response of eosinophilic and non-eosinophilic asthma
2007
The role of T lymphocytes in the pathogenesis of asthma
2003
Inhaled beclomethasone dipropionate downregulates airway lymphocyte activation in atopic asthma.
1994
Mast Cell and Basophil Number in the Airway Correlate with the Bronchial Responsiveness of Asthmatics
1995
RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor
1998 StandoutNature
Asthma
2000 Standout
Airway Inflammation in Mild Intermittent and in Persistent Asthma
1998
Mechanisms of Eosinophil Recruitment
1993
Pirfenidone Modulates Airway Responsiveness, Inflammation, and Remodeling after Repeated Challenge
2006
Effect of Inhaled Interleukin-5 on Airway Hyperreactivity and Eosinophilia in Asthmatics
1998
Inflammation and Airway Function in Asthma
1998
Eosinophil's Role Remains Uncertain as Anti–Interleukin-5 only Partially Depletes Numbers in Asthmatic Airway
2003
Eosinophil-associated TGF- β 1 mRNA Expression and Airways Fibrosis in Bronchial Asthma
1997
Cytokines as Mediators of Chronic Asthma
1994
Glucocorticoid Receptor Isoforms α and β in in Vitro Cytokine-induced Glucocorticoid Insensitivity
2004
Evidence That Severe Asthma Can Be Divided Pathologically into Two Inflammatory Subtypes with Distinct Physiologic and Clinical Characteristics
1999
Evidence of Airway Inflammation and Remodeling in Ski Athletes with and without Bronchial Hyperresponsiveness to Methacholine
2000
Mechanisms of persistent airway inflammation in asthma. A role for T cells and T-cell products.
1995
Dissociation between Airway Inflammation and Airway Hyperresponsiveness in Allergic Asthma
1998
Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease
2012 Standout
Release of RANTES, MIP-1 α , and MCP-1 into Asthmatic Airways Following Endobronchial Allergen Challenge
1997
Relationship between IL-4 and IL-5 mRNA Expression and Disease Severity in Atopic Asthma
1997
Interleukin-4 Alters Epithelial Cell Differentiation and Surfactant Homeostasis in the Postnatal Mouse Lung
1997
Effect of cyclosporin A on the allergen-induced late asthmatic reaction
1997
The effect of inhaled sodium cromoglycate on cellular infiltration into the bronchial mucosa and the expression of adhesion molecules in asthmatics
1997
Activation of A3 adenosine receptors on human eosinophils elevates intracellular calcium
1996 StandoutNobel
Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma
1997
Mouse Eotaxin Expression Parallels Eosinophil Accumulation during Lung Allergic Inflammation but It Is Not Restricted to a Th2-Type Response
1996
An Essential Role of Mast Cells in the Development of Airway Hyperresponsiveness in a Murine Asthma Model
2000
Requirement for IL-13 Independently of IL-4 in Experimental Asthma
1998 StandoutScience
Immunoreactivity for interleukin 3 and 5 and granulocyte/macrophage colony-stimulating factor of intestinal mucosa in bronchial asthma.
1995
Increased numbers of dendritic cells in the bronchial mucosa of atopic asthmatic patients: downregulation by inhaled corticosteroids
1996
Anti-inflammatory effects of inhaled beclomethasone dipropionate in nonatopic asthmatics
1996
Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity.
1996
Activated memory T helper cells in bronchoalveolar lavage fluid from patients with atopic asthma: relation to asthma symptoms, lung function, and bronchial responsiveness.
1993
Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils.
1996
A Novel T Cell-Regulated Mechanism Modulating Allergen-Induced Airways Hyperreactivity in BALB/c Mice Independently of IL-4 and IL-5
1998
Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice.
1995
T cell-dependent regulation of eotaxin in antigen-induced pulmonary eosinophila.
1996
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model.
1996 Standout
The Coordinated Action of CC Chemokines in the Lung Orchestrates Allergic Inflammation and Airway Hyperresponsiveness
1998
Expression of Interleukin 9 in the Lungs of Transgenic Mice Causes Airway Inflammation, Mast Cell Hyperplasia, and Bronchial Hyperresponsiveness
1998
β-Arrestin-2 regulates the development of allergic asthma
2003 StandoutNobel
Airway eosinophilia and expression of interleukin‐5 protein in asthma and in exacerbations of chronic bronchitis
1996
Pathology of asthma
1992
Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation.
1994
Stenotrophomonas maltophilia: an Emerging Global Opportunistic Pathogen
2012 Standout
Interleukin-13: Central Mediator of Allergic Asthma
1998 StandoutScience
Influenza Virus–induced Dendritic Cell Maturation Is Associated with the Induction of Strong T Cell Immunity to a Coadministered, Normally Nonimmunogenic Protein
2003 StandoutNobel
Critical Role for IL-13 in the Development of Allergen-Induced Airway Hyperreactivity
2001
Induction of Airway Mucus Production By T Helper 2 (Th2) Cells: A Critical Role For Interleukin 4 In Cell Recruitment But Not Mucus Production
1997
The late asthmatic response is associated with baseline allergen‐specific proliferative responsiveness of peripheral T lymphocytes in vitro and serum interleukin‐5
1999
Relationship between the inflammatory infiltrate in bronchial biopsy specimens and clinical severity of asthma in patients treated with inhaled steroids.
1996
Bronchial biopsies and airway inflammation
1996
Cell matrix interactions in asthma
1997
Airway and lung elastic fibre is not reduced in asthma nor in asthmatics following corticosteroid treatment
1995
Genetic Susceptibility to Asthma — Bronchial Hyperresponsiveness Coinherited with a Major Gene for Atopy
1995
Effect of natural allergen exposure during the grass pollen season on airways inflammatory cells and asthma symptoms.
1996
Is there a unifying hypothesis for exercise-induced asthma?
1984
IMMUNOLOGIC BASIS OF ANTIGEN-INDUCED AIRWAY HYPERRESPONSIVENESS
1999
Works of B Assoufi being referenced
The effect of dexamethasone, cyclosporine, and rapamycin on T-lymphocyte proliferation in vitro: Comparison of cells from patients with glucocorticoid-sensitive and glucocorticoid-resistant chronic asthma
1994
Glucocorticoid resistant asthma: T-lymphocyte steroid metabolism and sensitivity to glucocorticoids and immunosuppressive agents
1996
Prednisolone Treatment in Asthma Is Associated with Modulation of Bronchoalveolar Lavage Cell Interleukin-4, Interleukin-5, and Interferon-γ Cytokine Gene Expression
1993
Increased expression of mRNA encoding RANTES and MCP-3 in the bronchial mucosa in atopic asthma
1996
Elevated expression of messenger ribonucleic acid encoding IL-13 in the bronchial mucosa of atopic and nonatopic subjects with asthma
1997
Secretion of the eosinophil‐active cytokines interleukin‐5, granulocyte/macrophage colonystimulating factor and interleukin‐3 by bronchoalveolar lavage CD4+ and CD8+ T cell lines in atopics asthmatics, and atopic and nonatopic controls
1995
Identification of Activated T Lymphocytes and Eosinophils in Bronchial Biopsies in Stable Atopic Asthma
1990
Human eosinophils express messenger RNA encoding RANTES and store and release biologically active RANTES protein
1996
IL-4 and IL-5 mRNA and protein in bronchial biopsies from patients with atopic and nonatopic asthma: evidence against "intrinsic" asthma being a distinct immunopathologic entity.
1996
Efficacy and safety of short-term administration of aerosolised recombinant human DNase I in adults with stable stage cystic fibrosis
1993
Eosinophils, T-lymphocytes, mast cells, neutrophils, and macrophages in bronchial biopsy specimens from atopic subjects with asthma: Comparison with biopsy specimens from atopic subjects without asthma and normal control subjects and relationship to bronchial hyperresponsiveness
1991
Prednisolone treatment in asthma. Reduction in the numbers of eosinophils, T cells, tryptase-only positive mast cells, and modulation of IL-4, IL-5, and interferon-gamma cytokine gene expression within the bronchial mucosa.
1996
Regular three monthly oral ciprofloxacin in adult cystic fibrosis patients infected with Pseudomonas aeruginosa
1993
Eosinophil cationic protein(ECP) and eosinophil protein X (EXP) concentrations in serum and bronchial lavage fluid in asthma. effect of prednisolone treatment.
1995
Direct recordings of the temperatures in the tracheobronchial tree in normal man.
1982
294 Eosinophils, T-lymphocytes, mast cells, neutrophils and macrophages in bronchial biopsies from atopic asthmatics: Comparison with atopic non-asthma and relationship to bronchial hyperresponsiveness
1991
Safety of fibreoptic bronchoscopy in asthmatic and control subjects and effect on asthma control over two weeks.
1996
THE LINK BETWEEN EXERCISE, RESPIRATORY HEAT EXCHANGE, AND THE MAST CELL IN BRONCHIAL ASTHMA
1983