Standout Papers
Citation Impact
Citing Papers
Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water
2017 StandoutScienceNobel
RNA buffers the phase separation behavior of prion-like RNA binding proteins
2018 Science
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
2017 Standout
Two isoforms of the essential C. elegans Argonaute CSR-1 differentially regulate sperm and oocyte fertility
2021 StandoutNobel
Origins of coevolution between residues distant in protein 3D structures
2017 StandoutNobel
Exploiting conformational dynamics to modulate the function of designed proteins
2023 StandoutNobel
In vivo aspects of protein folding and quality control
2016 Science
Phase separation of a yeast prion protein promotes cellular fitness
2018 Science
ATP sensing in living plant cells reveals tissue gradients and stress dynamics of energy physiology
2017
ZSP‐1 is a Z granule surface protein required for Z granule fluidity and germline immortality in Caenorhabditis elegans
2021
Phosphorylation of the FUS low‐complexity domain disrupts phase separation, aggregation, and toxicity
2017
Formation, chemical evolution and solidification of the dense liquid phase of calcium (bi)carbonate
2024 StandoutNobel
The ϕPA3 phage nucleus is enclosed by a self-assembling 2D crystalline lattice
2023 StandoutNobel
Par complex cluster formation mediated by phase separation
2020
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
2024 StandoutNobel
Stress-Induced Low Complexity RNA Activates Physiological Amyloidogenesis
2018
In Vivo Formation of Vacuolated Multi-phase Compartments Lacking Membranes
2016
The role of liquid–liquid phase separation in aggregation of the TDP-43 low-complexity domain
2019 Standout
Are aberrant phase transitions a driver of cellular aging?
2016
Biomolecular condensates: organizers of cellular biochemistry
2017 Standout
Regulation of microRNA function in animals
2018 Standout
Biomolecular Condensates and Cancer
2021
Coexisting Liquid Phases Underlie Nucleolar Subcompartments
2016
Parkinson's disease
2021 Standout
Methods for Physical Characterization of Phase-Separated Bodies and Membrane-less Organelles
2018
Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments
2018
Acetylation of intrinsically disordered regions regulates phase separation
2018
Different Material States of Pub1 Condensates Define Distinct Modes of Stress Adaptation and Recovery
2018
Transcription Factors Activate Genes through the Phase-Separation Capacity of Their Activation Domains
2018
Phase behaviour of disordered proteins underlying low density and high permeability of liquid organelles
2017
Hallmarks of aging: An expanding universe
2023 Standout
Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains
2017
Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II
2015
TRIBE: Hijacking an RNA-Editing Enzyme to Identify Cell-Specific Targets of RNA-Binding Proteins
2016 StandoutNobel
C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles
2016
NMR spectroscopy captures the essential role of dynamics in regulating biomolecular function
2021
Integrating single-cell transcriptomic data across different conditions, technologies, and species
2018 Standout
Quality Control of Membraneless Organelles
2018
RNA Controls PolyQ Protein Phase Transitions
2015
Intracellular production of hydrogels and synthetic RNA granules by multivalent molecular interactions
2017
Liquid Nuclear Condensates Mechanically Sense and Restructure the Genome
2018
Decoding ALS: from genes to mechanism
2016 StandoutNature
ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
2016
Probing and engineering liquid-phase organelles
2019
Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
2019 Standout
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Transport Selectivity of Nuclear Pores, Phase Separation, and Membraneless Organelles
2015
Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation
2018 Standout
Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Sclerosis
2018
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
Atlas of Subcellular RNA Localization Revealed by APEX-Seq
2019
Intrinsically disordered sequences enable modulation of protein phase separation through distributed tyrosine motifs
2017
A User’s Guide for Phase Separation Assays with Purified Proteins
2018
Applications of contact predictions to structural biology
2017 StandoutNobel
Amyloid-like Self-Assembly of a Cellular Compartment
2016
Sequence Determinants of Intracellular Phase Separation by Complex Coacervation of a Disordered Protein
2016
Protein Phase Separation: A New Phase in Cell Biology
2018
Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules
2021
Ubiquitin Modulates Liquid-Liquid Phase Separation of UBQLN2 via Disruption of Multivalent Interactions
2018
Principles and Properties of Stress Granules
2016
Structured States of Disordered Proteins from Genomic Sequences
2016
Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation
2018
Biophysical characterization of organelle-based RNA/protein liquid phases using microfluidics
2016
Human Mesenchymal Stem Cells as a Carrier for a Cell-Mediated Drug Delivery
2022 StandoutNobel
Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins
2012 Standout
Fluorescence nanoscopy in cell biology
2017 StandoutNobel
Membraneless organelles can melt nucleic acid duplexes and act as biomolecular filters
2016
RNA-binding proteins in human genetic disease
2020
Enhancing glycolysis attenuates Parkinson’s disease progression in models and clinical databases
2019
Compositional Control of Phase-Separated Cellular Bodies
2016
A glass menagerie of low complexity sequences
2016
Nuclear Import Receptor Inhibits Phase Separation of FUS through Binding to Multiple Sites
2018
Sequence determinants of protein phase behavior from a coarse-grained model
2018
Phase Transition in Postsynaptic Densities Underlies Formation of Synaptic Complexes and Synaptic Plasticity
2016
The Centrosome Is a Selective Condensate that Nucleates Microtubules by Concentrating Tubulin
2017
A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins
2018
The LC Domain of hnRNPA2 Adopts Similar Conformations in Hydrogel Polymers, Liquid-like Droplets, and Nuclei
2015
Advances in Understanding Stimulus-Responsive Phase Behavior of Intrinsically Disordered Protein Polymers
2018
A Surveillance Function of the HSPB8-BAG3-HSP70 Chaperone Complex Ensures Stress Granule Integrity and Dynamism
2016
The proteostasis network and its decline in ageing
2019
Prion-like low-complexity sequences: Key regulators of protein solubility and phase behavior
2018
Phase Separation: Linking Cellular Compartmentalization to Disease
2016
Stress-Triggered Phase Separation Is an Adaptive, Evolutionarily Tuned Response
2017
CIDER: Resources to Analyze Sequence-Ensemble Relationships of Intrinsically Disordered Proteins
2017
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Essence determines phenomenon: Assaying the material properties of biological condensates
2022
Comprehensive Review on Alzheimer’s Disease: Causes and Treatment
2020 Standout
Relationship of Sequence and Phase Separation in Protein Low-Complexity Regions
2018
CAMELOT: A machine learning approach for coarse-grained simulations of aggregation of block-copolymeric protein sequences
2015
De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity
2024 StandoutNobel
Functional Implications of Intracellular Phase Transitions
2018
Natural and Designed Proteins Inspired by Extremotolerant Organisms Can Form Condensates and Attenuate Apoptosis in Human Cells
2022 StandoutNobel
Distinct stages in stress granule assembly and disassembly
2016
F‐domain valency determines outcome of signaling through the angiopoietin pathway
2021 StandoutNobel
Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins
2017
miRNA targeting and alternative splicing in the stress response – events hosted by membrane-less compartments
2018
CPEB4 is regulated during cell cycle by ERK2/Cdk1-mediated phosphorylation and its assembly into liquid-like droplets
2016
The wisdom of crowds: regulating cell function through condensed states of living matter
2017
Three‐dimensional correlative single‐cell imaging utilizing fluorescence and refractive index tomography
2017
Protein phase separation and its role in tumorigenesis
2020
Multilayer Capsules Inside Biological Systems: State-of-the-Art and Open Challenges
2019
Heat Shock Proteins in Alzheimer’s Disease: Role and Targeting
2018
Physical Principles Underlying the Complex Biology of Intracellular Phase Transitions
2020
Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines
2023 StandoutNobel
Oxidative Stress: A Key Modulator in Neurodegenerative Diseases
2019 Standout
Real-time imaging of Huntingtin aggregates diverting target search and gene transcription
2016 Nobel
E3 ubiquitin ligase Mindbomb 1 facilitates nuclear delivery of adenovirus genomes
2020 StandoutNobel
Atomic structures of low-complexity protein segments reveal kinked β sheets that assemble networks
2018 Science
Polymer physics of intracellular phase transitions
2015
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
Works of Avinash Patel being referenced
ATP as a biological hydrotrope
2017 Science
An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function
2017
A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation
2015 Standout