Standout Papers
Citation Impact
Citing Papers
Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells
2013 StandoutScience
Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq
2015 StandoutScience
Direct conversion of human fibroblasts to dopaminergic neurons
2011
DAF-16/FOXO and HLH-30/TFEB function as combinatorial transcription factors to promote stress resistance and longevity
2018 StandoutNobel
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
FOXO3 Shares Common Targets with ASCL1 Genome-wide and Inhibits ASCL1-Dependent Neurogenesis
2013
Hierarchical Mechanisms for Direct Reprogramming of Fibroblasts to Neurons
2013 StandoutNobel
Genetic and Epigenetic Determinants of Neurogenesis and Myogenesis
2012
Direct generation of functional dopaminergic neurons from mouse and human fibroblasts
2011 Nature
Old and new functions of proneural factors revealed by the genome-wide characterization of their transcriptional targets
2011
Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs
2019 StandoutNobel
Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors
2011 Nature
Direct Reprogramming of Mouse and Human Fibroblasts into Multipotent Neural Stem Cells with a Single Factor
2012
Transcriptional Regulation and Its Misregulation in Disease
2013
RNA-guided gene activation by CRISPR-Cas9–based transcription factors
2013
Generation of Human Melanocytes from Induced Pluripotent Stem Cells
2011 StandoutNobel
Pluripotent Stem Cells for the Study of CNS Development
2011
Induced pluripotent stem cells (iPSCs) and neurological disease modeling: progress and promises
2011
SoxC Transcription Factors Are Required for Neuronal Differentiation in Adult Hippocampal Neurogenesis
2012
Control of the Embryonic Stem Cell State
2011
Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1
2011 StandoutNatureNobel
Induced Pluripotent Stem Cells: Past, Present, and Future
2012 StandoutNobel
Crystal Structure of Cas9 in Complex with Guide RNA and Target DNA
2014 Standout
Classification and evolution of type II CRISPR-Cas systems
2014 StandoutNobel
Synaptotagmin-1 and Synaptotagmin-7 Trigger Synchronous and Asynchronous Phases of Neurotransmitter Release
2013 StandoutNobel
A Functional Role for Tumor Cell Heterogeneity in a Mouse Model of Small Cell Lung Cancer
2011
Direct Lineage Conversion of Terminally Differentiated Hepatocytes to Functional Neurons
2011 StandoutNobel
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
2017 Standout
Generation of Human Striatal Neurons by MicroRNA-Dependent Direct Conversion of Fibroblasts
2014
Neurotransmitter Release: The Last Millisecond in the Life of a Synaptic Vesicle
2013 StandoutNobel
In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes
2012 Nature
Transcription Factor-Induced Lineage Selection of Stem-Cell-Derived Neural Progenitor Cells
2011
Tumor Metastasis: Molecular Insights and Evolving Paradigms
2011 Standout
Remodeling Neurodegeneration: Somatic Cell Reprogramming-Based Models of Adult Neurological Disorders
2013
The Human Transcription Factors
2018 Standout
Reprogramming Cellular Identity for Regenerative Medicine
2012
Functional Integration of Dopaminergic Neurons Directly Converted from Mouse Fibroblasts
2011
Direct lineage conversions: unnatural but useful?
2011
Induction of functional hepatocyte-like cells from mouse fibroblasts by defined factors
2011 Nature
Direct conversion of human fibroblasts to multilineage blood progenitors
2010 Nature
Super-Enhancers in the Control of Cell Identity and Disease
2013 Standout
Direct Reprogramming of Fibroblasts into Neural Stem Cells by Defined Factors
2012
A unique chromatin signature uncovers early developmental enhancers in humans
2010 StandoutNature
Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells
2013 StandoutNobel
Ubiquitin-dependent regulation of COPII coat size and function
2012 StandoutNatureNobel
Pluripotency and Cellular Reprogramming: Facts, Hypotheses, Unresolved Issues
2010
Induced Pluripotent Stem Cells from Individuals with Recessive Dystrophic Epidermolysis Bullosa
2010
Conversion of Mouse and Human Fibroblasts into Functional Spinal Motor Neurons
2011
Skeletal muscle programming and re-programming
2013
Membrane-Tethered Monomeric Neurexin LNS-Domain Triggers Synapse Formation
2013 StandoutNobel
Cellular Reprogramming: Recent Advances in Modeling Neurological Diseases
2011
MicroRNA-based conversion of human fibroblasts into striatal medium spiny neurons
2015
Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts
2014
Direct Reprogramming of Adult Human Fibroblasts to Functional Neurons under Defined Conditions
2011
Development and Applications of CRISPR-Cas9 for Genome Engineering
2014 Standout
De novo design of bioactive protein switches
2019 StandoutNatureNobel
Heart repair by reprogramming non-myocytes with cardiac transcription factors
2012 Nature
limma powers differential expression analyses for RNA-sequencing and microarray studies
2015 Standout
Combinatorial function of transcription factors and cofactors
2017
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors
2010 Standout
Efficient induction of functional neurons from adult human fibroblasts
2011
Small molecules enable highly efficient neuronal conversion of human fibroblasts
2012
Accelerating progress in induced pluripotent stem cell research for neurological diseases
2012
Transcriptional regulation and nuclear reprogramming: roles of nuclear actin and actin-binding proteins
2012 StandoutNobel
Direct Reprogramming of Human Fibroblasts to Functional and Expandable Hepatocytes
2014
Efficiencies and Mechanisms of Nuclear Reprogramming
2010 StandoutNobel
Cell Fate Plug and Play: Direct Reprogramming and Induced Pluripotency
2011
Cerebral organoids model human brain development and microcephaly
2013 StandoutNature
Modeling psychiatric disorders at the cellular and network levels
2012
Metastatic colonization by circulating tumour cells
2016 StandoutNature
MicroRNA-mediated conversion of human fibroblasts to neurons
2011 Nature
The Human Brain in a Dish: The Promise of iPSC-Derived Neurons
2011
Induced Neuronal Cells: How to Make and Define a Neuron
2011 StandoutNobel
Synthesis of Heterobifunctional Protein Fusions Using Copper‐Free Click Chemistry and the Aldehyde Tag
2012 StandoutNobel
Molecular Roadblocks for Cellular Reprogramming
2012
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
Modeling Development and Disease with Organoids
2016 Standout
A decade of transcription factor-mediated reprogramming to pluripotency
2016 Nobel
Comprehensive qPCR profiling of gene expression in single neuronal cells
2011 StandoutNobel
Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
2013 Standout
Embryonic Stem Cells Induce Pluripotency in Somatic Cell Fusion through Biphasic Reprogramming
2012
Historical Origins of Transdifferentiation and Reprogramming
2011
Biopharmaceutical benchmarks 2010
2010
Nuclear reprogramming to a pluripotent state by three approaches
2010 StandoutNatureNobel
Advances in skin grafting and treatment of cutaneous wounds
2014 StandoutScience
Mice carrying a human GLUD2 gene recapitulate aspects of human transcriptome and metabolome development
2016 StandoutNobel
Organogenesis in a dish: Modeling development and disease using organoid technologies
2014 StandoutScience
How neuroinflammation contributes to neurodegeneration
2016 StandoutScience
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells
2012 StandoutNobel
Direct reprogramming of mouse fibroblasts to neural progenitors
2011
Radical Acceleration of Nuclear Reprogramming by Chromatin Remodeling with the Transactivation Domain of MyoD
2011
Emerging Targets in Photopharmacology
2016 StandoutNobel
Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation
2013 StandoutNobel
Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery
2017 StandoutNobel
Human in vitro models for understanding mechanisms of autism spectrum disorder
2020
Works of Austin Ostermeier being referenced
Direct conversion of fibroblasts to functional neurons by defined factors
2010 StandoutNatureNobel
Induction of human neuronal cells by defined transcription factors
2011 StandoutNatureNobel