Citation Impact
Citing Papers
Intracellular Tumor-Associated Antigens Represent Effective Targets for Passive Immunotherapy
2012 StandoutNobel
Immune Rejection of Mouse Tumors Expressing Mutated Self
2009 StandoutNobel
Intranodal Vaccination with Naked Antigen-Encoding RNA Elicits Potent Prophylactic and Therapeutic Antitumoral Immunity
2010
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Intratumoral Delivery of TriMix mRNA Results in T-cell Activation by Cross-Presenting Dendritic Cells
2016
Vaccination with mRNA-Electroporated Dendritic Cells Induces Robust Tumor Antigen-Specific CD4+ and CD8+ T Cells Responses in Stage III and IV Melanoma Patients
2012
Phase II Study of Autologous Monocyte-Derived mRNA Electroporated Dendritic Cells (TriMixDC-MEL) Plus Ipilimumab in Patients With Pretreated Advanced Melanoma
2016
Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose
2016
Self-assembled mRNA vaccines
2021
Ligand-tethered lipid nanoparticles for targeted RNA delivery to treat liver fibrosis
2023 StandoutNobel
Dendritic Cell Targeting of Survivin Protein in a Xenogeneic Form Elicits Strong CD4+ T Cell Immunity to Mouse Survivin
2006 StandoutNobel
Murine liver repair via transient activation of regenerative pathways in hepatocytes using lipid nanoparticle-complexed nucleoside-modified mRNA
2021 StandoutNobel
Intralymphatic mRNA vaccine induces CD8 T-cell responses that inhibit the growth of mucosally located tumours
2016
Nucleoside-modified VEGFC mRNA induces organ-specific lymphatic growth and reverses experimental lymphedema
2021 StandoutNobel
mRNA therapeutics in cancer immunotherapy
2021
Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge
2017 StandoutNobel
Toll-like receptor expression and function in human dendritic cell subsets: implications for dendritic cell-based anti-cancer immunotherapy
2010
Engineering precision nanoparticles for drug delivery
2020 Standout
Delivery of mRNA vaccines with heterocyclic lipids increases anti-tumor efficacy by STING-mediated immune cell activation
2019
Messenger RNA-Based Vaccines Against Infectious Diseases
2020 StandoutNobel
The challenge and prospect of mRNA therapeutics landscape
2020
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Dendritic cells engineered to secrete anti-GITR antibodies are effective adjuvants to dendritic cell-based immunotherapy
2009
mRNA Cancer Vaccines—Messages that Prevail
2017
Clinical-grade manufacturing of autologous mature mRNA-electroporated dendritic cells and safety testing in acute myeloid leukemia patients in a phase I dose-escalation clinical trial
2009
Enhancement of dendritic cells transfection in vivo and of vaccination against B16F10 melanoma with mannosylated histidylated lipopolyplexes loaded with tumor antigen messenger RNA
2011
Preclinical evaluation of an mRNA HIV vaccine combining rationally selected antigenic sequences and adjuvant signals (HTI-TriMix)
2016
Endogenous T-Cell Therapy
2015
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
Tissue-targeted therapy of autoimmune diabetes using dendritic cells transduced to express IL-4 in NOD mice
2008
mRNA-based cancer vaccine: prevention of B16 melanoma progression and metastasis by systemic injection of MART1 mRNA histidylated lipopolyplexes
2007
The European Regulatory Environment of RNA-Based Vaccines
2016
mRNA-based therapeutics — developing a new class of drugs
2014 StandoutNobel
Cotransfection of dendritic cells with RNA coding for HER-2/neu and 4-1BBL increases the induction of tumor antigen specific cytotoxic T lymphocytes
2005
Hydroxycholesterol substitution in ionizable lipid nanoparticles for mRNA delivery to T cells
2022 StandoutNobel
Dendritic cells transfected with interleukin-12 and tumor-associated antigen messenger RNA induce high avidity cytotoxic T cells
2006
Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA vaccines
2023 StandoutNobel
Enhancement of anti‐tumor immunity through local modulation of CTLA‐4 and GITR by dendritic cells
2011
Imaging in the era of molecular oncology
2008 StandoutNature
Prophylactic vaccines are potent activators of monocyte-derived dendritic cells and drive effective anti-tumor responses in melanoma patients at the cost of toxicity
2016
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
RNA: The new revolution in nucleic acid vaccines
2013
mRNA
2013
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
More efficient induction of antitumor T cell immunity by exosomes from CD40L gene-modified lung tumor cells
2013
Engineered lentivector targeting of dendritic cells for in vivo immunization
2008 Nobel
Type I IFN Counteracts the Induction of Antigen-Specific Immune Responses by Lipid-Based Delivery of mRNA Vaccines
2012
An ionizable lipid toolbox for RNA delivery
2021 StandoutNobel
mRNA-based dendritic cell vaccination induces potent antiviral T-cell responses in HIV-1-infected patients
2011
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
2021 StandoutNobel
Glucocorticoid-induced Tumor Necrosis Factor Receptor Negatively Regulates Activation of Human Primary Natural Killer (NK) Cells by Blocking Proliferative Signals and Increasing NK Cell Apoptosis
2008
Immune response and long-term clinical outcome in advanced melanoma patients vaccinated with tumor-mRNA-transfected dendritic cells
2016
Nanotechnologies in delivery of mRNA therapeutics using nonviral vector-based delivery systems
2017
Therapeutic implications of the TLR and VDR partnership
2007
Elimination of large tumors in mice by mRNA-encoded bispecific antibodies
2017 StandoutNobel
A novel, disruptive vaccination technology
2013
Dendritic cells in cancer immunotherapy
2010
The ReNAissanCe of mRNA-based cancer therapy
2014
Novel cancer immunotherapy agents with survival benefit: recent successes and next steps
2011 StandoutNobel
Materials for non-viral intracellular delivery of messenger RNA therapeutics
2015
mRNA-transfected dendritic cell vaccine in combination with metronomic cyclophosphamide as treatment for patients with advanced malignant melanoma
2016
Improving mRNA-Based Therapeutic Gene Delivery by Expression-Augmenting 3′ UTRs Identified by Cellular Library Screening
2018
Recent innovations in mRNA vaccines
2016
Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy
2017 Standout
mRNA transcript therapy
2014 StandoutNobel
T Cell Surveillance of Oncogene-Induced Prostate Cancer Is Impeded by T Cell-Derived TGF-β1 Cytokine
2011 StandoutNobel
Dendritic Cells In Vivo: A Key Target for a New Vaccine Science
2008 StandoutNobel
Cancer immunotherapy comes of age
2011 StandoutNature
Intranasal mRNA nanoparticle vaccination induces prophylactic and therapeutic anti-tumor immunity
2014
Introduction of functional chimeric E/L-selectin by RNA electroporation to target dendritic cells from blood to lymph nodes
2007
Immunotherapy of Diffuse Gliomas: Biological Background, Current Status and Future Developments
2009 Standout
Long Overall Survival After Dendritic Cell Vaccination in Metastatic Uveal Melanoma Patients
2014
Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
2012 StandoutNatureNobel
Clinical targeting of the TNF and TNFR superfamilies
2013
Biomedical applications of mRNA nanomedicine
2018
Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies
2018 StandoutNobel
Self-adjuvanted mRNA vaccines induce local innate immune responses that lead to a potent and boostable adaptive immunity
2016
iHIVARNA phase IIa, a randomized, placebo-controlled, double-blinded trial to evaluate the safety and immunogenicity of iHIVARNA-01 in chronically HIV-infected patients under stable combined antiretroviral therapy
2019
Delivering the Messenger: Advances in Technologies for Therapeutic mRNA Delivery
2019
Adjuvant-pulsed mRNA vaccine nanoparticle for immunoprophylactic and therapeutic tumor suppression in mice
2020
Identification of Cyclobutane Pyrimidine Dimer-Responsive Genes Using UVB-Irradiated Human Keratinocytes Transfected with In Vitro-Synthesized Photolyase mRNA
2015 StandoutNobel
mRNA as a Transformative Technology for Vaccine Development to Control Infectious Diseases
2019
Nanoparticles versus Dendritic Cells as Vehicles to Deliver mRNA Encoding Multiple Epitopes for Immunotherapy
2019
Tumor Necrosis Factor Inhibits Spread of Hepatitis C Virus Among Liver Cells, Independent From Interferons
2017 StandoutNobel
mRNA Cancer Vaccines
2016
The Unexpected Importance of the Primary Structure of the Hydrophobic Part of One-Component Ionizable Amphiphilic Janus Dendrimers in Targeted mRNA Delivery Activity
2022 StandoutNobel
Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy
2023 StandoutNobel
2015
Localized Multi‐Component Delivery Platform Generates Local and Systemic Anti‐Tumor Immunity
2016
Intensified and protective CD4+ T cell immunity in mice with anti–dendritic cell HIV gag fusion antibody vaccine
2006 StandoutNobel
Targeted and Equally Distributed Delivery of mRNA to Organs with Pentaerythritol-Based One-Component Ionizable Amphiphilic Janus Dendrimers
2023 StandoutNobel
Ionizable Lipid Nanoparticle-Mediated mRNA Delivery for Human CAR T Cell Engineering
2020
Stimulation of the Glucocorticoid-Induced TNF Receptor Family-Related Receptor on CD8 T Cells Induces Protective and High-Avidity T Cell Responses to Tumor-Specific Antigens
2010 StandoutNobel
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
Integrated NY-ESO-1 antibody and CD8+T-cell responses correlate with clinical benefit in advanced melanoma patients treated with ipilimumab
2011 StandoutNobel
Three decades of messenger RNA vaccine development
2019
The combination of 4-1BBL and CD40L strongly enhances the capacity of dendritic cells to stimulate HIV-specific T cell responses
2011
Increased Antigen Presentation Efficiency by Coupling Antigens to MHC Class I Trafficking Signals
2008
Database of T cell-defined human tumor antigens: the 2013 update.
2013
Nanotechnology for Multimodal Synergistic Cancer Therapy
2017 Standout
Nanomedicines to Deliver mRNA: State of the Art and Future Perspectives
2020
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
2008 StandoutNobel
A multivalent nucleoside-modified mRNA vaccine against all known influenza virus subtypes
2022 StandoutScienceNobel
Intranodal administration of mRNA encoding nucleoprotein provides cross-strain immunity against influenza in mice
2019
RNA-Based Vaccines in Cancer Immunotherapy
2015
Immune responses and long‐term disease recurrence status after telomerase‐based dendritic cell immunotherapy in patients with acute myeloid leukemia
2017
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Arginine‐Rich Peptide‐Based mRNA Nanocomplexes Efficiently Instigate Cytotoxic T Cell Immunity Dependent on the Amphipathic Organization of the Peptide
2017
Intratumoral administration of mRNA encoding a fusokine consisting of IFN-β and the ectodomain of the TGF-β receptor II potentiates antitumor immunity
2014
HUMAN T CELL RESPONSES AGAINST MELANOMA
2005
Targeted Delivery of mRNA with One-Component Ionizable Amphiphilic Janus Dendrimers
2021 StandoutNobel
Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells
2006
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
CD8 T Cell-Intrinsic GITR Is Required for T Cell Clonal Expansion and Mouse Survival following Severe Influenza Infection
2010 StandoutNobel
Scalable mRNA and siRNA Lipid Nanoparticle Production Using a Parallelized Microfluidic Device
2021 StandoutNobel
From the RNA world to the clinic
2016 Science
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
Throughput-scalable manufacturing of SARS-CoV-2 mRNA lipid nanoparticle vaccines
2023 StandoutNobel
Therapeutic cancer vaccines
2015
Recombinant messenger RNA technology and its application in cancer immunotherapy, transcript replacement therapies, pluripotent stem cell induction, and beyond
2015
Opportunities and Challenges in the Delivery of mRNA-Based Vaccines
2020
Efficient Nanovaccine Delivery in Cancer Immunotherapy
2017
Works of Aude Bonehill being referenced
Long-term clinical outcome of melanoma patients treated with messenger RNA-electroporated dendritic cell therapy following complete resection of metastases
2014
mRNA-based dendritic cell vaccines
2014
Delivery of Tumor-Antigen-Encoding mRNA into Dendritic Cells for Vaccination
2008
Electroporation of immature and mature dendritic cells: implications for dendritic cell-based vaccines
2005
Induction of Influenza Matrix Protein 1 and MelanA-specific T lymphocytes in vitro using mRNA-electroporated dendritic cells
2003
Genetic approaches for the induction of a CD4+ T cell response in cancer immunotherapy
2005
Engineering Dendritic Cells to Enhance Cancer Immunotherapy
2011
Epitope and HLA-type independent monitoring of antigen-specific T-cells after treatment with dendritic cells presenting full-length tumor antigens
2012
Current approaches in dendritic cell generation and future implications for cancer immunotherapy
2007
Optimized dendritic cell-based immunotherapy for melanoma: the TriMix-formula
2014
Overcoming HLA restriction in clinical trials
2012
Design of an Optimized Wilms’ Tumor 1 (WT1) mRNA Construct for Enhanced WT1 Expression and Improved Immunogenicity In Vitro and In Vivo
2013
CD83 expression on dendritic cells and T cells: Correlation with effective immune responses
2007
Dendritic Cells Loaded With mRNA Encoding Full-length Tumor Antigens Prime CD4+ and CD8+ T Cells in Melanoma Patients
2012
Induction of antigen-specific CD8+ cytotoxic T cells by dendritic cells co-electroporated with a dsRNA analogue and tumor antigen mRNA
2006
Intravenous and intradermal TriMix-dendritic cell therapy results in a broad T-cell response and durable tumor response in a chemorefractory stage IV-M1c melanoma patient
2011
Lentivirally transduced dendritic cells as a tool for cancer immunotherapy
2003
Single-Step Antigen Loading and Maturation of Dendritic Cells Through mRNA Electroporation of a Tumor-Associated Antigen and a TriMix of Costimulatory Molecules
2014
Enhancing the T-cell Stimulatory Capacity of Human Dendritic Cells by Co-electroporation With CD40L, CD70 and Constitutively Active TLR4 Encoding mRNA
2008
Engineering WT1-Encoding mRNA to Increase Translational Efficiency in Dendritic Cells
2016
Side-by-Side Comparison of Lentivirally Transduced and mRNA-Electroporated Dendritic Cells: Implications for Cancer Immunotherapy Protocols
2004
Immunotherapy of Cancer with Dendritic Cells Loaded with Tumor Antigens and Activated Through mRNA Electroporation
2010
Therapeutic Vaccination With an Autologous mRNA Electroporated Dendritic Cell Vaccine in Patients With Advanced Melanoma
2011
Functional T-cell responses generated by dendritic cells expressing the early HIV-1 proteins Tat, Rev and Nef
2008
A phase IB study on intravenous synthetic mRNA electroporated dendritic cell immunotherapy in pretreated advanced melanoma patients
2013
Induction of effective therapeutic antitumor immunity by direct in vivo administration of lentiviral vectors
2005
Restoration of tumor equilibrium after immunotherapy for advanced melanoma
2011
Activation of Monocytes via the CD14 Receptor Leads to the Enhanced Lentiviral Transduction of Immature Dendritic Cells
2004
Lumenal Part of the DC-LAMP Protein Is Not Required for Induction of Antigen-Specific T Cell Responses by Means of Antigen-DC-LAMP Messenger RNA-Electroporated Dendritic Cells
2009
Messenger RNA-Electroporated Dendritic Cells Presenting MAGE-A3 Simultaneously in HLA Class I and Class II Molecules
2004
Inefficient exogenous loading of a tapasin‐dependent peptide onto HLA ‐B *44:02 can be improved by acid treatment or fixation of target cells
2012
Expression of human GITRL on myeloid dendritic cells enhances their immunostimulatory function but does not abrogate the suppressive effect of CD4+CD25+ regulatory T cells
2007
Modulation of Regulatory T Cell Function by Monocyte-Derived Dendritic Cells Matured through Electroporation with mRNA Encoding CD40 Ligand, Constitutively Active TLR4, and CD70
2013
Preclinical Evaluation of TriMix and Antigen mRNA-Based Antitumor Therapy
2012
Characterization of CD8+T-Cell Responses in the Peripheral Blood and Skin Injection Sites of Melanoma Patients Treated with mRNA Electroporated Autologous Dendritic Cells (TriMixDC-MEL)
2013
Efficient presentation of known HLA class II-restricted MAGE-A3 epitopes by dendritic cells electroporated with messenger RNA encoding an invariant chain with genetic exchange of class II-associated invariant chain peptide.
2003
Phase IB study on combined intradermal (ID) and intravenous (IV) administration of autologous mRNA electroporated dendritic cells (DC) as a single-agent cellular immunotherapy or combined with ipilimumab.
2012
Dendritic cells differentiated in the presence of IFN-β and IL-3 are potent inducers of an antigen-specific CD8+ T cell response
2005
Single-Step Antigen Loading and Activation of Dendritic Cells by mRNA Electroporation for the Purpose of Therapeutic Vaccination in Melanoma Patients
2009