Atsuo Baba

Hedgehog signaling in tissue homeostasis, cancers and targeted therapies

Context-specific regulation of extracellular vesicle biogenesis and cargo selection

Structure-based discovery of cellular-active allosteric inhibitors of FAK

Discovery of the investigational drug TAK-441, a pyrrolo[3,2-c]pyridine derivative, as a highly potent and orally active hedgehog signaling inhibitor: Modification of the core skeleton for improved solubility