Citation Impact
Citing Papers
Trends in GPCR drug discovery: new agents, targets and indications
2017 Standout
The use of spirocyclic scaffolds in drug discovery
2014 Standout
Spirocyclic replacements for the isatin in the highly selective, muscarinic M1 PAM ML137: The continued optimization of an MLPCN probe molecule
2013
Development of allosteric modulators of GPCRs for treatment of CNS disorders
2013
Works of Atin Lamsal being referenced
Discovery of N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)isonicatinamide, ML293, as a novel, selective and brain penetrant positive allosteric modulator of the muscarinic 4 (M4) receptor
2012
Discovery of a selective M4 positive allosteric modulator based on the 3-amino-thieno[2,3-b]pyridine-2-carboxamide scaffold: Development of ML253, a potent and brain penetrant compound that is active in a preclinical model of schizophrenia
2012
Chemical Modification of the M1Agonist VU0364572 Reveals Molecular Switches in Pharmacology and a Bitopic Binding Mode
2012