Citation Impact
Citing Papers
Systemic Delivery of Microencapsulated 3-Bromopyruvate for the Therapy of Pancreatic Cancer
2014 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Recruitment of Stem and Progenitor Cells from the Bone Marrow Niche Requires MMP-9 Mediated Release of Kit-Ligand
2002 Standout
Matrix metalloproteinases and the regulation of tissue remodelling
2007 Standout
Potency and selectivity of RXP407 on human, rat, and mouse angiotensin-converting enzyme
2001
Matrix metalloproteinase activity assays: Importance of zymography
2010
Reactions in Droplets in Microfluidic Channels
2006 Standout
Recent advances in 1,3-dipolar cycloaddition reactions on solid supports
2005
Total Synthesis of Abyssomicin C and atrop‐Abyssomicin C
2006
Catalytic Activities and Substrate Specificity of the Human Membrane Type 4 Matrix Metalloproteinase Catalytic Domain
1999
Total Synthesis of (−)‐atrop‐Abyssomicin C
2012
Cancer Metastasis: Building a Framework
2006 Standout
Low-Density Lipoprotein Receptor-Related Protein-1 Mediates Endocytic Clearance of Tissue Inhibitor of Metalloproteinases-1 and Promotes Its Cytokine-Like Activities
2014 StandoutNobel
Targeting proteases: successes, failures and future prospects
2006
Tumor Metastasis: Molecular Insights and Evolving Paradigms
2011 Standout
A New Role for TIMP-1 in Modulating Neurite Outgrowth and Morphology of Cortical Neurons
2009
Alternative Splicing and Promoter Usage Generates an Intracellular Stromelysin 3 Isoform Directly Translated as an Active Matrix Metalloproteinase
2002
Heat Shock Protein A12B Protects Vascular Endothelial Cells Against Sepsis-Induced Acute Lung Injury in Mice
2017 Standout
Role of the N-terminal Catalytic Domain of Angiotensin-converting Enzyme Investigated by Targeted Inactivation in Mice
2004 StandoutNobel
Iterative In Situ Click Chemistry Creates Antibody‐like Protein‐Capture Agents
2009 StandoutNobel
Epilysin, a Novel Human Matrix Metalloproteinase (MMP-28) Expressed in Testis and Keratinocytes and in Response to Injury
2001
Solid phase peptide synthesis utilizing 9‐fluorenylmethoxycarbonyl amino acids
1990 Standout
The involvement of matrix metalloproteinases 2 and 9 in rat retinal ischemia
2006
Recent advances in MMP inhibitor design
2006
The tissue inhibitors of metalloproteinases (TIMPs): An ancient family with structural and functional diversity
2010
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
The Catalytic Asymmetric Abramov Reaction
2014 StandoutNobel
Remodelling the extracellular matrix in development and disease
2014 Standout
Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting
2010
Crystal structure of the complex formed by the membrane type 1-matrix metalloproteinase with the tissue inhibitor of metalloproteinases-2, the soluble progelatinase A receptor
1998
A Simple Enantioconvergent and Chemoenzymatic Synthesis of Optically Active α‐Substituted Amides
2011 StandoutNobel
Involvement of tissue inhibition of metalloproteinases-1 in learning and memory in mice
2006
Tumor metastasis: mechanistic insights and clinical challenges
2006 Standout
The angiotensin converting enzyme (ACE)
2003
Catalytic Asymmetric Synthesis of Phosphine Boronates
2015 StandoutNobel
Comprehensive survey of chemical libraries yielding enzyme inhibitors, receptor agonists and antagonists, and other biologically active agents: 1992 through 1997
1997
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Myocardial Matrix Remodeling and the Matrix Metalloproteinases: Influence on Cardiac Form and Function
2007
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Asymmetric Multicomponent Reactions (AMCRs): The New Frontier
2005 Standout
Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy
2006
Organic Azides: An Exploding Diversity of a Unique Class of Compounds
2005 Standout
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
2014 Standout
Nmr in drug discovery
2002 StandoutNobel
Metzincin Proteases and Their Inhibitors: Foes or Friends in Nervous System Physiology?
2010
Matrix Metalloproteinases
1999 Standout
Strategies for Discovering and Derisking Covalent, Irreversible Enzyme Inhibitors
2010
Iron-Catalyzed Reactions in Organic Synthesis
2004 Standout
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Remarkable Potential of the α-Aminophosphonate/Phosphinate Structural Motif in Medicinal Chemistry
2011
Peptidotriazoles on Solid Phase: [1,2,3]-Triazoles by Regiospecific Copper(I)-Catalyzed 1,3-Dipolar Cycloadditions of Terminal Alkynes to Azides
2002 StandoutNobel
Monofluorination of Organic Compounds: 10 Years of Innovation
2015 Standout
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Chemistry of Polyvalent Iodine
2008 Standout
Review: Update on Newer Antihypertensive Medicines and Interventions
2010
Synthesis of Amidines Derived from Phosphonates and Phosphane Oxides − Amidine‐Mediated Preparation of Phosphorylated Oxazolines
2003
Solid Phase Combinatorial Library of Phosphinic Peptides for Discovery of Matrix Metalloproteinase Inhibitors
2000 StandoutNobel
In Vivo Imaging of Matrix Metalloproteinase 12 and Matrix Metalloproteinase 13 Activities in the Mouse Model of Collagen‐Induced Arthritis
2013 StandoutNobel
VEGF Secreted by Hypoxic Müller Cells Induces MMP-2 Expression and Activity in Endothelial Cells to Promote Retinal Neovascularization in Proliferative Diabetic Retinopathy
2013 StandoutNobel
The extracellular matrix: A dynamic niche in cancer progression
2012 Standout
Angiotensin-Converting Enzyme C-Terminal Catalytic Domain Is the Main Site of Angiotensin I Cleavage In Vivo
2007 StandoutNobel
Glide: A New Approach for Rapid, Accurate Docking and Scoring. 1. Method and Assessment of Docking Accuracy
2004 Standout
Asymmetric catalysis as a method for the synthesis of chiral organophosphorus compounds
2014
Palladium-Catalyzed Cross-Coupling of H-Phosphinate Esters with Chloroarenes
2011
Copper-Catalyzed Synthesis of Mixed Alkyl Aryl Phosphonates
2014 StandoutNobel
In Vitro and In Vivo Inhibition of the 2 Active Sites of ACE by Omapatrilat, a Vasopeptidase Inhibitor
2000
Comprehensive Survey of Combinatorial Library Synthesis: 1999
2000
Comprehensive Survey of Combinatorial Library Synthesis: 2005
2006
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
Aza-Wittig reaction of N-phosphorylalkyl phosphazenes with carbonyl compounds and phenylisocyanate. Synthesis of 4-amino-3-phosphoryl-2-azadienes and pyrazine-phosphonates
2003
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Matrix Metalloproteinase Inhibitors and Cancer—Trials and Tribulations
2002 StandoutScience
The ADAMs: signalling scissors in the tumour microenvironment
2008
Activatable Photosensitizers for Imaging and Therapy
2010 Standout
Advances in Synthetic Applications of Hypervalent Iodine Compounds
2016 Standout
Fmoc-Based Synthesis of Peptide-αThioesters: Application to the Total Chemical Synthesis of a Glycoprotein by Native Chemical Ligation
1999 StandoutNobel
Angiotensin-Converting Enzyme Is Involved in Outside-In Signaling in Endothelial Cells
2003
ACTIVE ESTERS IN THE FORMATION OF ESTER BONDS BETWEEN AMINO ACIDS AND POLYMERIC SUPPORTS
1977
Mechanisms and prevention of trifluoroacetylation in solid-phase peptide synthesis
1979 StandoutNobel
Characterization of the first non-insect invertebrate functional angiotensin-converting enzyme (ACE): leech TtACE resembles the N-domain of mammalian ACE
2004
Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases
2003 Standout
Visible‐Light Photocatalysis: Does It Make a Difference in Organic Synthesis?
2018 Standout
Design and Therapeutic Application of Matrix Metalloproteinase Inhibitors
1999
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
The “One-Bead-One-Compound” Combinatorial Library Method
1997
‘On-water’ synthesis of chromeno-isoxazoles mediated by [hydroxy(tosyloxy)iodo]benzene (HTIB)
2010
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Recent developments in transferred NOE methods
1994
Palladium‐Catalyzed Intramolecular Sulfonamidation/Oxidation of Imines: Access to Multifunctional Benzimidazoles
2011
Synthesis of 5‐(Fluoromethyl)‐4,5‐dihydroisoxazoles by Silver‐ Catalyzed Oxyfluorination of Unactivated Alkenes
2014
Gold(I)-Catalyzed Activation of Alkynes for the Construction of Molecular Complexity
2015 Standout
Works of Athanasios Yiotakis being referenced
Membrane Type-1 Matrix Metalloprotease and Stromelysin-3 Cleave More Efficiently Synthetic Substrates Containing Unusual Amino Acids in Their P1′ Positions
1998
Proton and tritium nmr relaxation studies of peptide inhibitor binding to bacterial collagenase: Conformation and dynamics
1991
Development of Highly Potent and Selective Phosphinic Peptide Inhibitors of Zinc Endopeptidase 24-15 Using Combinatorial Chemistry
1995
Inhibition of Zinc Metallopeptidases in Cardiovascular Disease - From Unity to Trinity, or Duality?
2009
Development of Selective Inhibitors and Substrate of Matrix Metalloproteinase-12
2006
Development of the First Potent and Selective Inhibitor of the Zinc Endopeptidase Neurolysin Using a Systematic Approach Based on Combinatorial Chemistry of Phosphinic Peptides
1996
Synthetic active site-directed inhibitors of metzincins: Achievement and perspectives
2008
Combining Combinatorial Chemistry and Affinity Chromatography
2003
Phosphinic peptides as zinc metalloproteinase inhibitors
2004
Dosing and scheduling influence the antitumor efficacy of a phosphinic peptide inhibitor of matrix metalloproteinases
2004
Diastereoselective Solution and Multipin‐Based Combinatorial Array Synthesis of a Novel Class of Potent Phosphinic Metalloprotease Inhibitors
2003
Cross‐Linking Yield Variation of a Potent Matrix Metalloproteinase Photoaffinity Probe and Consequences for Functional Proteomics
2007
Crystal structure of the stromelysin-3 (MMP-11) catalytic domain complexed with a phosphinic inhibitor mimicking the transition-state11Edited by R. Huber
2001
Tissue inhibitor of metalloproteinases‐1 (TIMP‐1) modulates neuronal death, axonal plasticity, and learning and memory
2005
Matrix metalloproteinase 11 (MMP‐11; stromelysin‐3) and synthetic inhibitors
2006
Future challenges facing the development of specific active-site-directed synthetic inhibitors of MMPs
2004
Design, Synthesis, and Evaluation of Novel Organophosphorus Inhibitors of Bacterial Ureases
2008
Rapid Access to the Tricyclic Spirotetronic Core of Abyssomicins
2005
Selective Angiotensin-Converting Enzyme C-Domain Inhibition Is Sufficient to Prevent Angiotensin I–Induced Vasoconstriction
2004
Phosphinic Tripeptides as Dual Angiotensin-Converting Enzyme C-Domain and Endothelin-Converting Enzyme-1 Inhibitors
2009
Evaluation of P1'-Diversified Phosphinic Peptides Leads to the Development of Highly Selective Inhibitors of MMP-11
2003
RXP 407, a Selective Inhibitor of the N-Domain of Angiotensin I-Converting Enzyme, Blocks in Vivo the Degradation of Hemoregulatory Peptide Acetyl-Ser-Asp-Lys-Pro with No Effect on Angiotensin I Hydrolysis
2001
Convenient Synthesis and Diversification of Dehydroalaninyl Phosphinic Peptide Analogues
2001
Protection of the Hydroxyphosphinyl Function of Phosphinic Dipeptides by Adamantyl. Application to the Solid-Phase Synthesis of Phosphinic Peptides
1996
RXP 407, a phosphinic peptide, is a potent inhibitor of angiotensin I converting enzyme able to differentiate between its two active sites
1999
Rat liver injury following normothermic ischemia is prevented by a phosphinic matrix metalloproteinase inhibitor
2001
Side reactions in peptide synthesis. 4. Extensive O-acylation by active esters in histidine containing peptides
1977
Phosphinic Peptides: Synthetic Approaches and Biochemical Evaluation as Zn-Metalloprotease Inhibitors
2004
N ? -linked arginine peptides
1976
Roles of the Two Active Sites of Somatic Angiotensin-Converting Enzyme in the Cleavage of Angiotensin I and Bradykinin
2003
Computer-Aided Optimization of Phosphinic Inhibitors of Bacterial Ureases
2010
Structural Determinants of RXPA380, a Potent and Highly Selective Inhibitor of the Angiotensin-Converting Enzyme C-Domain
2004
Phosphinic Pseudo-Tripeptides as Potent Inhibitors of Matrix Metalloproteinases: A Structure−Activity Study
1999
Phosphinic peptide analogues as potent inhibitors of Corynebacterium rathayii bacterial collagenase
1994
Synthesis and Comparative Study on the Reactivity of Peptidyl-Type Phosphinic Esters: Intramolecular Effects in the Alkaline and Acidic Cleavage of Methyl β-Carboxyphosphinates
2001