Citation Impact
Citing Papers
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
The c-Jun N-Terminal Kinase Cascade Plays a Role in Stress-Induced Apoptosis in Jurkat Cells by Up-Regulating Fas Ligand Expression
1998
Functional diversity of helper T lymphocytes
1996 StandoutNature
A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
1997 StandoutNature
Targeted Disruption of the Mouse Caspase 8 Gene Ablates Cell Death Induction by the TNF Receptors, Fas/Apo1, and DR3 and Is Lethal Prenatally
1998
Spatio-temporal Dynamics of Protein Kinase B/Akt Signaling Revealed by a Genetically Encoded Fluorescent Reporter
2004 StandoutNobel
AP-1 function and regulation
1997 Standout
Daxx, a Novel Fas-Binding Protein That Activates JNK and Apoptosis
1997 Nobel
Early Activation of c-Jun N-terminal Kinase and p38 Kinase Regulate Cell Survival in Response to Tumor Necrosis Factor α
1998
Differential Kinetic and Spatial Patterns of β-Arrestin and G Protein-mediated ERK Activation by the Angiotensin II Receptor
2004 StandoutNobel
Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death
1996 Standout
Derailed endocytosis: an emerging feature of cancer
2008
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
2000 StandoutNature
Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor
1999 Standout
Apoptosis by Death Factor
1997 Standout
Loss of Net as Repressor Leads to Constitutive Increased c-fos Transcription in Cervical Cancer Cells
2004 StandoutNobel
Signal transduction by the c-Jun N-terminal kinase (JNK) — from inflammation to development
1998
Phosphorylation of IκB-α Inhibits Its Cleavage by Caspase CPP32 in Vitro
1997 StandoutNobel
Ras signalling and apoptosis
1998
The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells
2005
aPKCζ cortical loading is associated with Lgl cytoplasmic release and tumor growth in Drosophila and human epithelia
2007
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
Phosphoinositide 3-kinase in immunological systems
2002
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Nrk, an X-linked Protein Kinase in the Germinal Center Kinase Family, Is Required for Placental Development and Fetoplacental Induction of Labor
2011 StandoutNobel
The microenvironment of the tumour–host interface
2001 StandoutNature
Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade
1998
Involvement of PI3K/Akt pathway in cell cycle progression, apoptosis, and neoplastic transformation: a target for cancer chemotherapy
2003
SEK1/MKK4 Is Required for Maintenance of a Normal Peripheral Lymphoid Compartment but Not for Lymphocyte Development
1998
β-Arrestin1 Mediates Insulin-like Growth Factor 1 (IGF-1) Activation of Phosphatidylinositol 3-Kinase (PI3K) and Anti-apoptosis
2003 StandoutNobel
Non-ATP competitive protein kinase inhibitors as anti-tumor therapeutics
2009
NF-κB in cancer: a marked target
2003
Different Properties of SEK1 and MKK7 in Dual Phosphorylation of Stress-induced Activated Protein Kinase SAPK/JNK in Embryonic Stem Cells
2003 StandoutNobel
Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation
1992 StandoutNature
Mammalian MAP kinase signalling cascades
2001 StandoutNature
Caspase-mediated cleavage and functional changes of hematopoietic progenitor kinase 1 (HPK1)
1999
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
1998 StandoutNature
Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting
2012 StandoutNatureNobel
Phosphorylation of H2AX at Short Telomeres in T Cells and Fibroblasts
2004 StandoutNobel
NF-κB functions as a tumour promoter in inflammation-associated cancer
2004 StandoutNature
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Inhibition of death receptor signals by cellular FLIP
1997 StandoutNature
NF-κB at the crossroads of life and death
2002 Standout
Defects in the Ubiquitin Pathway Induce Caspase-independent Apoptosis Blocked by Bcl-2
1998 StandoutNobel
Impaired apoptosis, extended duration of immune responses, and a lupus-like autoimmune disease in IEX-1-transgenic mice
2002 StandoutNobel
The Bcl-2 Protein Family: Arbiters of Cell Survival
1998 StandoutScience
Ubiquitous and lymphocyte-specific factors are involved in the induction of the mouse interleukin 2 gene in T lymphocytes.
1989
Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors
1997 StandoutScience
Requirement of JNK for Stress- Induced Activation of the Cytochrome c-Mediated Death Pathway
2000 StandoutScience
Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis
1995 StandoutScience
Cyclosporin A suppresses the expression of the interleukin 2 gene by inhibiting the binding of lymphocyte-specific factors to the IL-2 enhancer.
1990
GATA-3-dependent enhancer activity in IL-4 gene regulation.
1998
Defective liver formation and liver cell apoptosis in mice lacking the stress signaling kinase SEK1/MKK4
1999
Regulator of G Protein Signaling Proteins: Novel Multifunctional Drug Targets
2001
Iterative in Situ Click Chemistry Assembles a Branched Capture Agent and Allosteric Inhibitor for Akt1
2011 StandoutNobel
NF-κB Antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to Suppress Caspase-8 Activation
1998 StandoutScience
Death Receptors: Signaling and Modulation
1998 StandoutScience
Trk Receptors: Roles in Neuronal Signal Transduction
2003 Standout
Coupling of Stress in the ER to Activation of JNK Protein Kinases by Transmembrane Protein Kinase IRE1
2000 StandoutScience
Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations
2000 StandoutScienceNobel
The Role of Caspases in Development, Immunity, and Apoptotic Signal Transduction
1999
Identification of a Small Molecule with Synthetic Lethality for K-Ras and Protein Kinase C Iota
2008
Genetic Dissection of Complex Traits
1994 StandoutScience
Cutting Edge: GATA-3-Dependent Enhancer Activity in IL-4 Gene Regulation
1998
Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans
2015 StandoutNobel
Linkage Analysis of IL4 and Other Chromosome 5q31.1 Markers and Total Serum Immunoglobulin E Concentrations
1994 Science
MATURE T LYMPHOCYTE APOPTOSIS—Immune Regulation in a Dynamic and Unpredictable Antigenic Environment
1999
Interleukin-13: Central Mediator of Allergic Asthma
1998 StandoutScience
The Receptor for the Cytotoxic Ligand TRAIL
1997 StandoutScience
A Cell Culture Model for T Lymphocyte Clonal Anergy
1990 StandoutScience
The Pim kinases control rapamycin-resistant T cell survival and activation
2005
Cell Survival Promoted by the Ras-MAPK Signaling Pathway by Transcription-Dependent and -Independent Mechanisms
1999 StandoutScience
Interleukin-3-Induced Phosphorylation of BAD Through the Protein Kinase Akt
1997 StandoutScience
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
Dissecting Fas signaling with an altered-specificity death-domain mutant: Requirement of FADD binding for apoptosis but not Jun N-terminal kinase activation
1999 Nobel
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
2001 Standout
Signal Transduction through MAP Kinase Cascades
1998 Standout
Withdrawal of Survival Factors Results in Activation of the JNK Pathway in Neuronal Cells Leading to Fas Ligand Induction and Cell Death
1999
Works of Astrid Eder being referenced
Hie 5′ region of the human interleukin 4 gene: structure and potential regulatory elements
1988
Phosphoinositide 3-Kinase Regulation of T Cell Receptor-mediated Interleukin-2 Gene Expression in Normal T Cells
1998
Regulation of BAD phosphorylation at serine 112 by the Ras-mitogen-activated protein kinase pathway
1999
T cell-specific negative regulation of transcription of the human cytokine IL-4.
1992
Lack of a Role for Jun Kinase and AP-1 in Fas-Induced Apoptosis
1997
Atypical PKCι contributes to poor prognosis through loss of apical-basal polarity and Cyclin E overexpression in ovarian cancer
2005
Lysophospholipid Growth Factors in the Initiation, Progression, Metastases, and Management of Ovarian Cancer
2000