Citation Impact
Citing Papers
rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data
2014 Standout
Generation of ordered protein assemblies using rigid three-body fusion
2021 StandoutNobel
Two isoforms of the essential C. elegans Argonaute CSR-1 differentially regulate sperm and oocyte fertility
2021 StandoutNobel
Characterization of a canine homolog of hepatitis C virus
2011 StandoutNobel
In vivo aspects of protein folding and quality control
2016 Science
Flavivirus Replication Complex Assembly Revealed by DNAJC14 Functional Mapping
2012 StandoutNobel
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors
2020 StandoutScienceNobel
Sculpting conducting nanopore size and shape through de novo protein design
2024 StandoutScienceNobel
Hierarchical design of pseudosymmetric protein nanocages
2024 StandoutNatureNobel
The ϕPA3 phage nucleus is enclosed by a self-assembling 2D crystalline lattice
2023 StandoutNobel
Elucidating Tau function and dysfunction in the era of cryo-EM
2019
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy
2022 StandoutNobel
Merging Molecular Electron Microscopy and Mass Spectrometry by Carbon Film-assisted Endoproteinase Digestion
2010
Ultrastructural Characterization of the Lower Motor System in a Mouse Model of Krabbe Disease
2016 Standout
The box C/D and H/ACA snoRNPs: key players in the modification, processing and the dynamic folding of ribosomal RNA
2011
A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching
2011 StandoutNobel
Non-uniform refinement: adaptive regularization improves single-particle cryo-EM reconstruction
2020 Standout
Direct-acting and host-targeting HCV inhibitors: current and future directions
2012
Regulation of microRNA biogenesis
2014 Standout
Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells
2010 StandoutNobel
Unconventional miR-122 binding stabilizes the HCV genome by forming a trimolecular RNA structure
2013 StandoutNobel
Dawning of a new era in TRP channel structural biology by cryo-electron microscopy
2018
Hepatitis C viral protein translation: mechanisms and implications in developing antivirals
2011
The DDX6–4E-T interaction mediates translational repression and P-body assembly
2016
Formation of the 3′ end of histone mRNA: Getting closer to the end
2007
An SMN-Dependent U12 Splicing Event Essential for Motor Circuit Function
2012
Dynamic RNA Modifications in Gene Expression Regulation
2017 Standout
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Structural and Functional Insights into Saccharomyces cerevisiae Tpa1, a Putative Prolylhydroxylase Influencing Translation Termination and Transcription
2010
Metazoan MicroRNAs
2018 Standout
Structure of a Yeast 40S–eIF1–eIF1A–eIF3–eIF3j initiation complex
2015
The dependence of viral RNA replication on co-opted host factors
2011
RNA and Disease
2009
Structure of mammalian eIF3 in the context of the 43S preinitiation complex
2015 StandoutNatureNobel
Dual regulation of hepatitis C viral RNA by cellular RNAi requires partitioning of Ago2 to lipid droplets and P-bodies
2011
Genome-wide Analysis of Pre-mRNA 3′ End Processing Reveals a Decisive Role of Human Cleavage Factor I in the Regulation of 3′ UTR Length
2012
The ins and outs of hepatitis C virus entry and assembly
2013 StandoutNobel
U1 snRNP regulates cancer cell migration and invasion in vitro
2020 Standout
Hepatitis C Virus Subverts Liver-Specific miR-122 to Protect the Viral Genome from Exoribonuclease Xrn2
2014
The advent of de novo proteins for cancer immunotherapy
2020
Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins
2012 Standout
The functional RNA domain 5BSL3.2 within the NS5B coding sequence influences hepatitis C virus IRES-mediated translation
2011
5′ UTR m6A Promotes Cap-Independent Translation
2015 Standout
Non-coding RNAs: lessons from the small nuclear and small nucleolar RNAs
2007
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Biology of PIWI-interacting RNAs: new insights into biogenesis and function inside and outside of germlines
2012
The Noncoding RNA Revolution—Trashing Old Rules to Forge New Ones
2014 Standout
Hepatitis C Virus RNA Translation
2013
Hepatitis C virus 3′UTR regulates viral translation through direct interactions with the host translation machinery
2013 StandoutNobel
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
SMN Requirement for Synaptic Vesicle, Active Zone and Microtubule Postnatal Organization in Motor Nerve Terminals
2011
Building Better Barrels – β-barrel Biogenesis and Insertion in Bacteria and Mitochondria
2021
Cryo-EM structure of a type IV secretion system
2022 StandoutNatureNobel
A day in the life of the spliceosome
2014
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
The SF3b complex: splicing and beyond
2020
The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates – identification of conserved and divergent features based on orthologue analysis
2014
RNA helicases at work: binding and rearranging
2010
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
RNA–protein analysis using a conditional CRISPR nuclease
2013 StandoutNobel
eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation
2016 StandoutNatureNobel
Regulation of Hepatitis C Virus Translation and Infectious Virus Production by the MicroRNA miR-122
2010
Recombinant Hepatitis C Virus Envelope Glycoprotein Vaccine Elicits Antibodies Targeting Multiple Epitopes on the Envelope Glycoproteins Associated with Broad Cross-Neutralization
2014 StandoutNobel
Characterization of nonprimate hepacivirus and construction of a functional molecular clone
2015 StandoutNobel
Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus
2012 StandoutNobel
Structure and Function of the 26S Proteasome
2018
Dephosphorylation of survival motor neurons (SMN) by PPM1G/PP2Cγ governs Cajal body localization and stability of the SMN complex
2007
Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy
2014 StandoutNobel
Neutralizing Monoclonal Antibodies against Hepatitis C Virus E2 Protein Bind Discontinuous Epitopes and Inhibit Infection at a Postattachment Step
2011
Increased Replicative Fitness Can Lead to Decreased Drug Sensitivity of Hepatitis C Virus
2014 StandoutNobel
Viral persistence, liver disease, and host response in a hepatitis C–like virus rat model
2017 StandoutNobel
Native Folding of a Recombinant gpE1/gpE2 Heterodimer Vaccine Antigen from a Precursor Protein Fused with Fc IgG
2016 StandoutNobel
Role of the E2 Hypervariable Region (HVR1) in the Immunogenicity of a Recombinant Hepatitis C Virus Vaccine
2018 StandoutNobel
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
Competing and noncompeting activities of miR-122 and the 5′ exonuclease Xrn1 in regulation of hepatitis C virus replication
2012
Distinct Mechanisms of Transcription Initiation by RNA Polymerases I and II
2018
Poly(C)-Binding Protein 2 Interacts with Sequences Required for Viral Replication in the Hepatitis C Virus (HCV) 5′ Untranslated Region and Directs HCV RNA Replication through Circularizing the Viral Genome
2011
Top-down design of protein architectures with reinforcement learning
2023 StandoutScienceNobel
Structural insights into TRPM8 inhibition and desensitization
2019 StandoutScienceNobel
OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation
2014 StandoutNobel
Protein Assembly by Design
2021
Reconfigurable asymmetric protein assemblies through implicit negative design
2022 StandoutScienceNobel
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
Works of Ashwin Chari being referenced
Molecular architecture of the Saccharomyces cerevisiae activated spliceosome
2016 Science
Structural Basis of Assembly Chaperone- Mediated snRNP Formation
2013
Long-range allosteric regulation of the human 26S proteasome by 20S proteasome-targeting cancer drugs
2017
An Assembly Chaperone Collaborates with the SMN Complex to Generate Spliceosomal SnRNPs
2008
IGHMBP2 is a ribosome-associated helicase inactive in the neuromuscular disorder distal SMA type 1 (DSMA1)
2009
Cryo-EM in drug discovery: achievements, limitations and prospects
2018
Deciphering the assembly pathway of Sm‐class U snRNPs
2008
Cellular strategies for the assembly of molecular machines
2010
Spinal muscular atrophy: the RNP connection
2006
Toward an Assembly Line for U7 snRNPs
2005
Translation Initiation Factor eIF3b Contains a Nine-Bladed β-Propeller and Interacts with the 40S Ribosomal Subunit
2014
Biogenesis of spliceosomal small nuclear ribonucleoproteins
2011
ProteoPlex: stability optimization of macromolecular complexes by sparse-matrix screening of chemical space
2015
Sample preparation of biological macromolecular assemblies for the determination of high-resolution structures by cryo-electron microscopy
2015
Arginine methylation in subunits of mammalian pre-mRNA cleavage factor I
2010
Unrip, a factor implicated in cap-independent translation, associates with the cytosolic SMN complex and influences its intracellular localization
2005
Atomic-resolution protein structure determination by cryo-EM
2020 Nature
Translation and replication of hepatitis C virus genomic RNA depends on ancient cellular proteins that control mRNA fates
2009
Evolution of an RNP assembly system: A minimal SMN complex facilitates formation of UsnRNPs in Drosophila melanogaster
2008