Citation Impact
Citing Papers
Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein
1994 Standout
Focal Stimulation of the Mossy Fibers Releases Endogenous Dynorphins That Bind K1‐Opioid Receptors in Guinea Pig Hippocampus
1991
Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain
1990 Standout
Mechanisms and Functional Implications of Adult Neurogenesis
2008 Standout
Anti‐mitotic activity of colchicine and the structural basis for its interaction with tubulin
2007
Endocannabinoid-Mediated Long-Term Plasticity Requires cAMP/PKA Signaling and RIM1α
2007 StandoutNobel
Endogenous dynorphins inhibit excitatory neurotransmission and block LTP induction in the hippocampus
1993 Nature
Prolonged Kappa Opioid Receptor Phosphorylation Mediated by G-protein Receptor Kinase Underlies Sustained Analgesic Tolerance
2004 StandoutNobel
Catalytic Enantioselective Reformatsky Reaction with Aldehydes
2008 StandoutNobel
The antisense homology box: A new motif within proteins that encodes biologically active peptides
1995 StandoutNobel
Nonsynaptic communication in the central nervous system
2004
Insight into tubulin regulation from a complex with colchicine and a stathmin-like domain
2004 StandoutNature
The multifarious hippocampal mossy fiber pathway: a review
2000
G protein coupled receptor dimerization: implications in modulating receptor function
2001
β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
2005 StandoutNature
Catalytic C–H functionalization by metal carbenoid and nitrenoid insertion
2008 StandoutNature
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
Kappa opioid receptor-like immunoreactivity in guinea pig brain: Ultrastructural localization in presynaptic terminals in hippocampal formation
1996
Phenserine and ring C hetero‐analogues: Drug candidates for the treatment of Alzheimer's disease
1995
G Protein-coupled Receptors
1998 StandoutNobel
The opioid peptide dynorphin mediates heterosynaptic depression of hippocampal mossy fibre synapses and modulates long-term potentiation
1993 Nature
A Role for cAMP in Long-Term Depression at Hippocampal Mossy Fiber Synapses
1998 StandoutNobel
Immunoaffinity‐purified opiate receptor specifically binds the δ‐class opiate receptor ligand, cis‐(+)‐3‐methylfentanylisothiocyanate, SUPERFIT
1987
Preliminary Pharmacological Evaluation of Enantiomeric Morphinans
2014
What we can do and what we cannot do with fMRI
2008 StandoutNature
A Ligand‐Library Approach to the Highly Efficient Rhodium/Phosphoramidite‐Catalyzed Asymmetric Arylation of N,N‐Dimethylsulfamoyl‐Protected Aldimines
2006 StandoutNobel
The next frontier in the molecular biology of the opioid system
1987
Opioid inhibition of GABA release from presynaptic terminals of rat hippocampal interneurons
1992
Neuroprotective and anti-amnesic potentials of sigma (σ) receptor ligands
1997
Reduced Cell Surface Expression of CCR5 in CCR5Δ32 Heterozygotes Is Mediated by Gene Dosage, Rather Than by Receptor Sequestration
2002 StandoutNobel
Interactions of colchicine with tubulin
1991
Anticancer drug design based on plant-derived natural products
1999
Dimerization of the δ Opioid Receptor:
1997
RIM1α is required for presynaptic long-term potentiation
2002 StandoutNatureNobel
The molecular neurobiology of depression
2008 StandoutNature
Organization of the stress system and its dysregulation in melancholic and atypical depression: high vs low CRH/NE states
2002
Nociceptors: the sensors of the pain pathway
2010 StandoutNobel
The synaptic vesicle cycle: a cascade of protein–protein interactions
1995 StandoutNatureNobel
Seeding “one-dimensional crystallization” of amyloid: A pathogenic mechanism in Alzheimer's disease and scrapie?
1993 Standout
Versatile Access to Chiral Indolines by Catalytic Asymmetric Fischer Indolization
2013 StandoutNobel
Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival
2007 Standout
Opiates inhibit neurogenesis in the adult rat hippocampus
2000
Synthesis of Oxacycles Employing the Oxa‐Pictet–Spengler Reaction: Recent Developments and New Prospects
2011
Enhanced Morphine Analgesia in Mice Lacking β-Arrestin 2
1999 StandoutScienceNobel
Catalytic Asymmetric Dearomatizing Redox Cross Coupling of Ketones with Aryl Hydrazines Giving 1,4-Diketones
2015 StandoutNobel
Animal Models of Nociception
2001
The Reformatsky reaction in organic synthesis. Recent advances
2004
Unresponsiveness to Cannabinoids and Reduced Addictive Effects of Opiates in CB 1 Receptor Knockout Mice
1999 StandoutScience
A DEMONSTRATION OF NALOXONE‐PRECIPITATED OPIATE WITHDRAWAL ON SINGLE NEURONES IN THE MORPHINE‐TOLERANT/DEPENDENT RAT BRAIN
1980
Simple Synthesis of Racemic Pyrrolo[2,3-b]indoles: Formal Total Synthesis of (±)-Physostigmine
2002
Opiate receptor knockout mice define μ receptor roles in endogenous nociceptive responses and morphine-induced analgesia
1997
Epilepsy and Exacerbation of Brain Injury in Mice Lacking the Glutamate Transporter GLT-1
1997 Science
Structural and conformational relationships between the enkephalins and the opiates
1976 Nature
Synthesis of Pyridine and Dihydropyridine Derivatives by Regio- and Stereoselective Addition toN-Activated Pyridines
2012 Standout
Characterizing the Site and Mode of Action of Dynorphin at Hippocampal Mossy Fiber Synapses in the Guinea Pig
1996
Regional Brain Activity Changes Associated with Fentanyl Analgesia Elucidated by Positron Emission Tomography
1997
Precipitation of morphine withdrawal syndrome in rats by administration of mu-, delta- and kappa-selective opioid antagonists
1992
A presynaptic locus for long-term potentiation of elementary synaptic transmission at mossy fiber synapses in culture.
1996 StandoutNobel
Morphinomimetic activity of synthetic fragments of beta-lipotropin and analogs.
1976 StandoutNobel
Total Synthesis of α-Pyrone Meroterpenoids, Novel Bioactive Microbial Metabolites
2005 StandoutNobel
Recent developments in indole ring synthesis—methodology and applications
2000 Standout
The Sonogashira Reaction: A Booming Methodology in Synthetic Organic Chemistry
2007 Standout
μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence
2000 StandoutNatureNobel
Asymmetric Catalysis by Architectural and Functional Molecular Engineering: Practical Chemo- and Stereoselective Hydrogenation of Ketones
2001 StandoutNobel
A Formal [3 + 3] Cycloaddition Approach to Natural‐Product Synthesis
2004
1-Substituted 4-(3-Hydroxyphenyl)piperazines Are Pure Opioid Receptor Antagonists
2010
Catalytic Dehydrogenative Cross-Coupling: Forming Carbon−Carbon Bonds by Oxidizing Two Carbon−Hydrogen Bonds
2011 Standout
Dose-dependent Regional Cerebral Blood Flow Changes during Remifentanil Infusion in Humans
2001
Azine Activation via Silylium Catalysis
2021 StandoutNobel
Synthesis and Opioid Receptor Binding Affinities of 2-Substituted and 3-Aminomorphinans: Ligands for μ, κ, and δ Opioid Receptors
2009
Enhanced Rewarding Properties of Morphine, but not Cocaine, in βarrestin-2 Knock-Out Mice
2003 StandoutNobel
Placebo and Opioid Analgesia-- Imaging a Shared Neuronal Network
2002 StandoutScience
Cellular and Molecular Mechanisms of Drug Dependence
1988 StandoutScience
Differential Mechanisms of Morphine Antinociceptive Tolerance Revealed in βArrestin-2 Knock-Out Mice
2002 StandoutNobel
Die Chemie vicinaler Diamine
1998
The Stereoselective Formation of Bicyclic Enamines with Bridgehead Unsaturation via Tandem C−H Bond Activation/Alkenylation/Electrocyclization
2008
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Highly Regioselective Synthesis of 3,4-Disubstituted 1H-Pyrrole,1
2000
Opiate Receptor: Demonstration in Nervous Tissue
1973 StandoutScience
Orphanin FQ: A Neuropeptide That Activates an Opioidlike G Protein-Coupled Receptor
1995 StandoutScience
Enantioselective addition of aryllithium reagents to aromatic imines mediated by 1,2-diamine ligands
2004
Recent applications of chiral allenes in axial-to-central chirality transfer reactions
2014
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Chiral Allenes via Alkynylogous Mukaiyama Aldol Reaction
2016 StandoutNobel
Anatomy of CNS opioid receptors
1988
Emerging Targets in Photopharmacology
2016 StandoutNobel
An antibody to a peptide specified by an RNA that is complementary to γ-endorphin mRNA recognizes an opiate receptor
1986
Animal models of nociception.
2001
Nitrated Confined Imidodiphosphates Enable a Catalytic Asymmetric Oxa-Pictet–Spengler Reaction
2016 StandoutNobel
Stereochemical Factors and Receptor Interactions Associated with Narcotic Analgesics
1966
Kappa Opioid Receptor Tolerance in the Guinea Pig Hippocampus
1997
The Catalytic Asymmetric Fischer Indolization
2011 StandoutNobel
Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation
2009 Standout
Structural Basis of Type II Topoisomerase Inhibition by the Anticancer Drug Etoposide
2011 StandoutScience
Aryl−Aryl Bond Formation One Century after the Discovery of the Ullmann Reaction
2002 Standout
Identification of an Opioid κ Receptor Subtype-Selective N-Substituent for (+)-(3R,4R)-Dimethyl-4-(3-hydroxyphenyl)piperidine
1998
LTP and memory: can we enhance the connection?
1993
Synthesis and Pharmacology of Potential Cocaine Antagonists. 2. Structure−Activity Relationship Studies of Aromatic Ring-Substituted Methylphenidate Analogs
1996
Works of Arthur E. Jacobson being referenced
Alterations in the stereochemistry of the .kappa.-selective opioid agonist U50,488 result in high-affinity .sigma. ligands
1989
A novel and facile preparation of bremazocine enantiomers through optically pure N-norbremazocines
2003
The development of a potential single photon emission computed tomography (SPECT) imaging agent for the corticotropin-releasing hormone receptor type 1
2001
Metaphit inhibits dopamine transport and binding of [3H] methylphenidate, a proposed marker for the dopamine transport complex
1989
Antipodal .alpha.-N-(Methyl through Decyl)-N-normetazocines (5,9.alpha.-Dimethyl-2'-hydroxy-6,7-benzomorphans): In vitro and In vivo Properties
1994
RTI-4614-4: An analog of (+)-cis-3-methylfentanyl with a 27,000-fold binding selectivity for mu versus delta opioid binding sites
1991
Opioid receptors on cells of the immune system: evidence for δ- and κ-classes
1989
μ-, δ- and κ-opioid receptor-mediated inhibition of neurotransmitter release and adenylate cyclase activity in rat brain slices: studies with fentanyl isothiocyanate
1988
Pharmacological activities of optically pure enantiomers of the κ opioid agonist, U50,488, and its cis diastereomer: evidence for three κ receptor subtypes
1989
Interaction of enantiomeric pairs of opiates with phencyclidine binding sites in rat brain: Identification of (+) pentazocine as a ligand potentially suitable for imaging sigma binding sites using positron emission tomography
1988
Interaction of opioid peptides and other drugs with multiple kappa receptors in rat and human brain. Evidence for species differences
1992
Comparison of the effects of the acute administration of dexoxadrol, levoxadrol, MK-801 and phencyclidine on body temperature in the rat
1989
Structures Related to Morphine. XXVII.1 α- and β-5,9-Diethyl-2-methyl-6,7-benzomorphans
1964
(.+-.)-2-Depentylperhydrohistrionicotoxin: a new probe for a regulatory site on the nicotinic acetylcholine receptor-channel
1982
Biological effects of modified colchicines. 2. Evaluation of catecholic colchicines, colchifolines, colchicide, and novel N-acyl- and N-aroyldeacetylcolchicines
1983
Analgesic Activity as Determined by the Nilsen Method
1972
Morphine tolerance increases μ-noncompetative δ binding sites
1986
Probes for narcotic receptor mediated phenomena. 12. cis-(+)-3-Methylfentanyl isothiocyanate, a potent site-directed acylating agent for .delta. opioid receptors. Synthesis, absolute configuration, and receptor enantioselectivity
1986
Distribution of opiate receptor subtypes and enkephalin and dynorphin immunoreactivity in the hippocampus of squirrel, guinea pig, rat, and hamster
1987
Purification of the opiate receptor of NG108-15 neuroblastoma-glioma hybrid cells.
1985
Deoxymorphines: role of the phenolic hydroxyl in antinociception and opiate receptor interactions
1979
Enantioconvergent Synthesis of (−)-(2R,5S)-1-Allyl-2,5-dimethylpiperazine, an Intermediate to δ-Opioid Receptor Ligands
2003
4-Methoxy-1-methylpyridinium iodide. Grignard products and transformations thereof
1969
Studies in the (+)-morphinan series. 5. Synthesis and biological properties of (+)-naloxone
1978
δ Opioid Affinity and Selectivity of 4-Hydroxy-3-methoxyindolomorphinan Analogues Related to Naltrindole
1999
Comparison of (-)-eseroline with (+)-eseroline and dihydroseco analogs in antinociceptive assays: confirmation of rubreserine structure by x-ray analysis
1986
Anticonvulsant activities of 1-phenylcyclohexylamine and its conformationally restricted analog 1,1-pentamethylenetetrahydroisoquinoline.
1989
Structures Related to Morphine. XXXI.1 2'-Substituted Benzomorphans
1965
Biological effects of modified colchicines. Improved preparation of 2-demethylcolchicine, 3-demethylcolchicine, and (+)-colchicine and reassignment of the position of the double bond in dehydro-7-deacetamidocolchicines
1981