Citation Impact
Citing Papers
Activity-Dependent Internalization of Smoothened Mediated by ß-Arrestin 2 and GRK2
2004 StandoutScienceNobel
Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia
2004 StandoutScience
Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4
2003 StandoutScienceNobel
A unique mechanism of β-blocker action: Carvedilol stimulates β-arrestin signaling
2007 StandoutNobel
Osteoclast Differentiation Factor Acts as a Multifunctional Regulator in Murine Osteoclast Differentiation and Function
1999
The c-Jun NH2-terminal Kinase Promotes Insulin Resistance during Association with Insulin Receptor Substrate-1 and Phosphorylation of Ser307
2000
Differential targeting of MAP kinases to the ETS-domain transcription factor Elk-1
1998
α-Synuclein Protects against Oxidative Stress via Inactivation of the c-Jun N-terminal Kinase Stress-signaling Pathway in Neuronal Cells
2002
Inflammation and cancer
2002 StandoutNature
Inflammation and metabolic disorders
2006 StandoutNature
The Reelin Receptor ApoER2 Recruits JNK-interacting Proteins-1 and -2
2000
Differential Kinetic and Spatial Patterns of β-Arrestin and G Protein-mediated ERK Activation by the Angiotensin II Receptor
2004 StandoutNobel
Signal Transduction by the JNK Group of MAP Kinases
2000 Standout
Oncogenic kinase signalling
2001 StandoutNature
Distinct β-Arrestin- and G Protein-dependent Pathways for Parathyroid Hormone Receptor-stimulated ERK1/2 Activation
2006 StandoutNobel
Role of the stress-activated protein kinases in endothelin-induced cardiomyocyte hypertrophy.
1998
Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor
1999 Standout
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Interaction of c-Jun Amino-terminal Kinase Interacting Protein-1 with p190 rhoGEF and Its Localization in Differentiated Neurons
1999
Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways
1996
The type III epidermal growth factor receptor mutation
2001
Bcr–Abl variants: biological and clinical aspects
2002
Identification of the Critical Features of a Small Peptide Inhibitor of JNK Activity
2002
Signal transduction by the c-Jun N-terminal kinase (JNK) — from inflammation to development
1998
The gene MAPK8IP1, encoding islet-brain-1, is a candidate for type 2 diabetes
2000
The cell-surface heparan sulfate proteoglycan glypican-1 regulates growth factor action in pancreatic carcinoma cells and is overexpressed in human pancreatic cancer.
1998
From JNK to Pay Dirt: Jun Kinases, their Biochemistry, Physiology and Clinical Importance
2005
Regulated portals of entry into the cell
2003 StandoutNature
cDNA Cloning and Mapping of a Novel Islet-Brain/JNK-Interacting Protein
2000
IB1 Reduces Cytokine-induced Apoptosis of Insulin-secreting Cells
2000
Structural organization of MAP-kinase signaling modules by scaffold proteins in yeast and mammals
1998
A central role for JNK in obesity and insulin resistance
2002 StandoutNature
Activation of p38 Mitogen-activated Protein Kinase by c-Abl-dependent and -independent Mechanisms
1996
MEK Kinase 3 Directly Activates MKK6 and MKK7, Specific Activators of the p38 and c-Jun NH2-terminal Kinases
1999
Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3(Mkk3)-deficient mice
1999
IB1, a JIP-1-related Nuclear Protein Present in Insulin-secreting Cells
1998
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
TAK1 is a ubiquitin-dependent kinase of MKK and IKK
2001 StandoutNature
Activation of the JNK pathway is important for cardiomyocyte death in response to simulated ischemia
1999
Organization and regulation of mitogen-activated protein kinase signaling pathways
1999
From endoplasmic-reticulum stress to the inflammatory response
2008 StandoutNature
Concentration-dependent positive and negative regulation of a MAP kinase by a MAP kinase kinase
1999
Osteoclast differentiation and activation
2003 StandoutNature
Phosphorylation of Ser307 in Insulin Receptor Substrate-1 Blocks Interactions with the Insulin Receptor and Inhibits Insulin Action
2002
Mammalian MAP kinase signalling cascades
2001 StandoutNature
What Do Scaffold Proteins Really Do?
2000
Structural basis of inhibitor selectivity in MAP kinases
1998
Expanding roles for β-arrestins as scaffolds and adapters in GPCR signaling and trafficking
2001 StandoutNobel
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
Human JIK, a Novel Member of the STE20 Kinase Family That Inhibits JNK and Is Negatively Regulated by Epidermal Growth Factor
1999
A role for JNK/SAPK in proliferation, but not apoptosis, of IL-3-dependent cells
1997
The Mixed Lineage Kinase DLK Utilizes MKK7 and Not MKK4 as Substrate
1999
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Chronic Myeloid Leukemia
1999
β-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking
2001 StandoutNobel
β-Arrestin2 mediates the initiation and progression of myeloid leukemia
2012 StandoutNobel
Bruton’s tyrosine kinase regulates apoptosis and JNK/SAPK kinase activity
1997
Dynamic regulation of c-Jun N-terminal kinase activity in mouse brain by environmental stimuli
1997
Detection and localization of MIP‐3α/LARC/exodus, a macrophage proinflammatory chemokine, and its CCR6 receptor in human pancreatic cancer
1999
The Bcl-2 Protein Family: Arbiters of Cell Survival
1998 StandoutScience
Mitogen-activated protein kinase kinase 7 is an activator of the c-Jun NH 2 -terminal kinase
1997
Spatial, temporal and subcellular localization of islet‐brain 1 (IB1), a homologue of JIP‐1, in mouse brain
2000
Requirement of JNK for Stress- Induced Activation of the Cytochrome c-Mediated Death Pathway
2000 StandoutScience
The Protein Kinase Complement of the Human Genome
2002 StandoutScience
Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2
2003 StandoutNobel
A Mammalian Scaffold Complex That Selectively Mediates MAP Kinase Activation
1998 Science
Defective lymphocyte chemotaxis in β-arrestin2- and GRK6-deficient mice
2002 StandoutNobel
Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions*
2001 Standout
Identification of a Motif in the Carboxyl Terminus of β-Arrestin2 Responsible for Activation of JNK3
2001 StandoutNobel
c-Jun NH2-Terminal Kinase Inhibits Targeting of the Protein Phosphatase Calcineurin to NFATc1
2000
The Elk-1 ETS-Domain Transcription Factor Contains a Mitogen-Activated Protein Kinase Targeting Motif
1998
β-Arrestin 2: A Receptor-Regulated MAPK Scaffold for the Activation of JNK3
2000 StandoutScienceNobel
Uses for JNK: the Many and Varied Substrates of the c-Jun N-Terminal Kinases
2006
KSR: a MAPK scaffold of the Ras pathway?
2001
Fluorine in Pharmaceuticals: Looking Beyond Intuition
2007 StandoutScience
β-Arrestin1 modulates lymphoid enhancer factor transcriptional activity through interaction with phosphorylated dishevelled proteins
2001 StandoutNobel
Integrin Signaling
1999 StandoutScience
Different G protein-coupled receptor kinases govern G protein and β-arrestin-mediated signaling of V2 vasopressin receptor
2005 StandoutNobel
The Jun Kinase 2 Isoform Is Preferentially Required for Epidermal Growth Factor-Induced Transformation of Human A549 Lung Carcinoma Cells
1999
Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases
2002 StandoutScience
The molecular biology of chronic myeloid leukemia
2000
Glypican-1 is overexpressed in human breast cancer and modulates the mitogenic effects of multiple heparin-binding growth factors in breast cancer cells.
2001
Functional antagonism of different G protein-coupled receptor kinases for β-arrestin-mediated angiotensin II receptor signaling
2005 StandoutNobel
Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes
2004 StandoutScience
Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human
1999 Standout
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
2001 StandoutNobel
Regulation of Mitogen-Activated Protein Kinase Signaling Networks by G Protein-Coupled Receptors
2000
Integrin-mediated Activation of Focal Adhesion Kinase Is Required for Signaling to Jun NH2-terminal Kinase and Progression through the G1 Phase of the Cell Cycle
1999
Structural Mechanism for STI-571 Inhibition of Abelson Tyrosine Kinase
2000 StandoutScience
Multiple Mitogen-Activated Protein Kinase Signaling Pathways Connect the Cot Oncoprotein to the c-junPromoter and to Cellular Transformation
2000
Regulation of MAP Kinase Signaling Modules by Scaffold Proteins in Mammals
2003
Inhibition of c-Jun N-Terminal Kinase 2 Expression Suppresses Growth and Induces Apoptosis of Human Tumor Cells in a p53-Dependent Manner
2000
A Network of Mitogen-Activated Protein Kinases Links G Protein-Coupled Receptors to the c-jun Promoter: a Role for c-Jun NH2-Terminal Kinase, p38s, and Extracellular Signal-Regulated Kinase 5
1999
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
2001 Standout
Signal Transduction through MAP Kinase Cascades
1998 Standout
Mutations in the DJ-1 Gene Associated with Autosomal Recessive Early-Onset Parkinsonism
2003 StandoutScience
Withdrawal of Survival Factors Results in Activation of the JNK Pathway in Neuronal Cells Leading to Fas Ligand Induction and Cell Death
1999
The JIP Group of Mitogen-Activated Protein Kinase Scaffold Proteins
1999
Interaction of a Mitogen-Activated Protein Kinase Signaling Module with the Neuronal Protein JIP3
2000
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
Transduction of Receptor Signals by ß-Arrestins
2005 StandoutScienceNobel
Desensitization, internalization, and signaling functions of β-arrestins demonstrated by RNA interference
2003 StandoutNobel
Works of Art Raitano being referenced
The Bcr-Abl leukemia oncogene activates Jun kinase and requires Jun for transformation.
1995
A Cytoplasmic Inhibitor of the JNK Signal Transduction Pathway
1997 Science
Tumor necrosis factor up-regulates gamma-interferon binding in a human carcinoma cell line.
1990