Citation Impact
Citing Papers
Crystal structure of a replication fork single-stranded DNA binding protein (T4 gp32) complexed to DNA
1995 StandoutNatureNobel
DNA interrogation by the CRISPR RNA-guided endonuclease Cas9
2014 StandoutNatureNobel
The promise and challenge of therapeutic genome editing
2020 StandoutNatureNobel
Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP
1985 StandoutNatureNobel
Calculation of protein extinction coefficients from amino acid sequence data
1989 Standout
Isolation and properties of transcribing ternary complexes of Escherichia coli RNA polymerase positioned at a single template base
1987
Delayed DNA joining at 3' mismatches by human DNA ligases
1999
Functional analysis of an archaebacterial voltage-dependent K+ channel
2003 StandoutNatureNobel
Crystal structure of globular domain of histone H5 and its implications for nucleosome binding
1993 StandoutNatureNobel
Sequence-specific DNA binding by theMspl DNA methyltransferase
1992 StandoutNobel
Structural basis for initiation of transcription from an RNA polymerase–promoter complex
1999 StandoutNatureNobel
An initiation site for meiotic gene conversion in the yeast Saccharomyces cerevisiae
1989 StandoutNatureNobel
Synergy between Escherichia coli CAP protein and RNA polymerase in the lac promoter open complex
1989
Structure of the recA protein–ADP complex
1992 StandoutNatureNobel
Principles for designing ideal protein structures
2012 StandoutNatureNobel
The RecA Protein: Structure and Functio
1990
A mediator required for activation of RNA polymerase II transcription in vitro
1991 StandoutNatureNobel
Runaway telomere elongation caused by telomerase RNA gene mutations
1995 StandoutNatureNobel
Structure of human cyclophilin and its binding site for cyclosporin A determined by X-ray crystallography and NMR spectroscopy
1991 StandoutNatureNobel
Asp537, Asp812 are essential and Lys631, His811 are catalytically significant in bacteriophage T7 RNA polymerase activity
1992
The structure of the E. coli recA protein monomer and polymer
1992 StandoutNatureNobel
Jak-STAT Pathways and Transcriptional Activation in Response to IFNs and Other Extracellular Signaling Proteins
1994 StandoutScience
Three-dimensional structure of Escherichia coli RNA polymerase holoenzyme determined by electron crystallography
1989 StandoutNatureNobel
Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats
1996 StandoutNatureNobel
DNA sequence determinants of CAP-induced bending and protein binding affinity
1988 Nature
Coordination of expression of DNA synthesis genes in budding yeast by a cell-cycle regulated trans factor
1991 Nature
Kemp elimination catalysts by computational enzyme design
2008 StandoutNatureNobel
DNA Bending Induced by the Catabolite Activator Protein Allows Ring Formation of a 144 bp DNA
1987
Computational redesign of endonuclease DNA binding and cleavage specificity
2006 StandoutNatureNobel
Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression
1998 StandoutNatureNobel
The interaction ofE.coliintegration host factor and λcosDNA: multiple complex formation and protein-induced bending
1989
Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements
1987
Interferon-induced binding of nuclear factors to promoter elements of the 2-5A synthetase gene.
1988
How to measure and predict the molar absorption coefficient of a protein
1995 Standout
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation
1990 StandoutNatureNobel
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
1996 StandoutNatureNobel
Mutations altering the cleavage specificity of a homing endonuclease
2002
Stringent spacing requirements for transcription activation by CRP
1990
Radioactive labeling of recombinant antibody fragments by phosphorylation using human casein kinase II and [γ-32P]-ATP
1996 StandoutNobel
Local Supercoil-Stabilized DNA Structure
1991
On the Processivity of DNA Replication
1983
De novo protein design by deep network hallucination
2021 StandoutNatureNobel
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
1997 Standout
EcoRV restriction endonuclease binds all DNA sequences with equal affinity
1991
Lysine 188 of the catabolite gene activator protein (CAP) plays no role in specificity at base pair 7 of the DNA half site
1990
Identification of a telomere-binding activity from yeast.
1986
Purification and characterization of proteins that bind to yeast ARSs.
1988
Single cell assay of a transcription factor reveals a threshold in transcription activated by signals emanating from the T-cell antigen receptor.
1990
The locus of sequence-directed and protein-induced DNA bending
1984 StandoutNature
Homologies Between Signal Transducing G Proteins and ras Gene Products
1984 StandoutScienceNobel
Distinct factors bind to apparently homolgous sequences in the immunoglobulin heavy-chain enhancer
1986 NatureNobel
Two distinct signal transmission pathways in T lymphocytes are inhibited by complexes formed between an immunophilin and either FK506 or rapamycin.
1990
Model of specific complex between catabolite gene activator protein and B-DNA suggested by electrostatic complementarity.
1984 StandoutNobel
Quantitation of Transcription and Clonal Selection of Single Living Cells with β-Lactamase as Reporter
1998 StandoutScienceNobel
Functional homology between signal-coupling proteins. Cholera toxin inactivates the GTPase activity of transducin.
1982
On the different binding affinities of CRP at thelac, galandmalT promoter regions
1983
Crystal Structure of a Group I Ribozyme Domain: Principles of RNA Packing
1996 StandoutScienceNobel
CAP and RNA polymerase interactions with thelacpromoter: binding stoichiometry and long range effects
1983
On the action of the cyclic AMP-cyclic AMP receptor protein complex at the Escherichia coli lactose and galactose promoter regions.
1984
Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis
1981 Standout
Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis
1995 StandoutScience
Cyclic AMP Receptor Protein: Role in Transcription Activation
1984 Science
Identification of factors that interact with the E1A-inducible adenovirus E3 promoter.
1987
Quality Control by DNA Repair
1999 StandoutScienceNobel
Unusual properties of promoter-up mutations in the Escherichia coli galactose operon and evidence suggesting RNA polymerase-induced DNA bending.
1987
A model for the non-specific binding of catabolite gene activator protein to DNA
1984 StandoutNobel
Specific interaction of cellular factors with the B enhancer of polyoma virus.
1985
Inducible binding of a factor to the c-fos enhancer
1986
Binding of the cyclic AMP receptor protein of Escherichia coli to RNA polymerase
1988
Two interferon-induced nuclear factors bind a single promoter element in interferon-stimulated genes.
1988
Probing the sequence-specific interaction of the cyclic AMP receptor protein with DNA by site-directed mutagenesis
1987
GTP binding protein: Properties and lack of activation by phosphorylated rhodopsin
1984
Structural Basis of Transcription: An RNA Polymerase II Elongation Complex at 3.3 Å Resolution
2001 StandoutScienceNobel
Isolation and sequence-specific DNA binding of the Antennapedia homeodomain.
1988 StandoutNobel
Structure of catabolite gene activator protein at 2.9 Å resolution suggests binding to left-handed B-DNA
1981 StandoutNatureNobel
A protein binds to a satellite DNA repeat at three specific sites that would be brought into mutual proximity by DNA folding in the nucleosome
1984
Binding of CRP to DNA-dependent RNA polymerase from E. coli: Modulation by cAMP of the interactions with free and DNA-bound holo and core enzyme
1980
Amino-terminal fragments of Escherichia coli lac repressor bind to DNA
1977 Nature
An equilibrium study of the cooperative binding of adenosine cyclic 3',5'-monophosphate and guanosine cyclic 3',5'-monophosphate to the adenosine cyclic 3',5'-monophosphate receptor protein from Escherichia coli
1980
Two DNA-binding factors recognize specific sequences at silencers, upstream activating sequences, autonomously replicating sequences, and telomeres in Saccharomyces cerevisiae.
1988 StandoutNobel
Yeast GCN4 transcriptional activator protein interacts with RNA polymerase II in vitro.
1989
The binding of the cyclic AMP receptor protein to synthetic DNA sites containing permutations in the consensus sequence TGTGA
1987
Coordinate ion pair formation between EcoRI endonuclease and DNA.
1983
Cytoplasmic activation of ISGF3, the positive regulator of interferon-alpha-stimulated transcription, reconstituted in vitro.
1989
Electrophoretic separation of complexes involved in the splicing of precursors to mRNAs
1986
Synergistic interaction between interferon-alpha and interferon-gamma through induced synthesis of one subunit of the transcription factor ISGF3.
1990
DNA Structure and Gene Regulation
1980
Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control.
1988
Kinetics and mechanism in the reaction of gene regulatory proteins with DNA
1984
Interferon gamma-induced transcription of the high-affinity Fc receptor for IgG requires assembly of a complex that includes the 91-kDa subunit of transcription factor ISGF3.
1993
Cocrystals of the DNA-binding domain of phage 434 repressor and a synthetic phage 434 operator.
1984
Multiple nuclear factors interact with the immunoglobulin enhancer sequences
1986 StandoutNobel
Mutants of the catabolite activator protein of Escherichia coli that are specifically deficient in the gene-activation function.
1987
D1 protein of Drosophila melanogaster. Purification and AT-DNA binding properties.
1985
Isolation of the amino-terminal fragment of lactose repressor necessary for DNA binding
1977
Variations of intramolecular ligation rates allow the detection of protein-induced bends in DNA.
1986
GCN4 protein, synthesize in vitro, binds HIS3 regulatory sequences: Implications for general control of amino acid biosynthetic genes in yeast
1985
Crystal Structure of a CAP-DNA Complex: the DNA Is Bent by 90°
1991 StandoutScienceNobel
Kinetics of Protein-Nucleic Acid Interactions: Use of Salt Effects to Probe Mechanisms of Interactio
1986
A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes
1986 NatureNobel
Equilibrium studies of the cyclic AMP receptor protein-DNA interaction
1984
ISGF3, the transcriptional activator induced by interferon alpha, consists of multiple interacting polypeptide chains.
1990
Efficient intracellular delivery of biomacromolecules employing clusters of zinc oxide nanowires
2017
Light-dependent phosphorylation of rhodopsin by β-adrenergic receptor kinase
1986 StandoutNatureNobel
The DNA binding domain and bending angle of E. coli CAP protein
1986
B Lineage—Specific Interactions of an Immunoglobulin Enhancer with Cellular Factors in Vivo
1985 StandoutScienceNobel
Activation of Transcription by IFN-γ: Tyrosine Phosphorylation of a 91-kD DNA Binding Protein
1992 Science
Specific DNA binding of the cAMP receptor protein within the lac operon stabilizes double-stranded DNA in the presence of cAMP.
1983
Diffusion-driven mechanisms of protein translocation on nucleic acids. 2. The Escherichia coli lac repressor-operator interaction: equilibrium measurements
1981
Ethylation interference and X-ray crystallography identify similar interactions between 434 repressor and operator
1985 Nature
The yeast branchpoint sequence is not required for the formation of a stable U1 snRNA-pre-mRNA complex and is recognized in the absence of U2 snRNA.
1991 StandoutNobel
Selection of DNA binding sites by regulatory proteins
1987
Nonspecific interaction of lac repressor with DNA: an association reaction driven by counterion release
1977
Action mechanism of Escherichia coli DNA photolyase. I. Formation of the enzyme-substrate complex.
1987 StandoutNobel
Identification and purification of a factor that binds to the Mlu I cell cycle box of yeast DNA replication genes.
1991 StandoutNobel
Mechanism of CRP-cAMP activation of lac operon transcription initiation activation of the P1 promoter
1984
Regulation of the Escherichia coli l-arabinose operon studied by gel electrophoresis DNA binding assay
1984
Cell-type-specific contacts to immunoglobulin enhancers in nuclei
1985 StandoutNatureNobel
Structure of E. coli Glutaminyl-tRNA Synthetase Complexed with tRNA Gln and ATP at 2.8 Å Resolution
1989 StandoutScienceNobel
λ Repressor and cro—components of an efficient molecular switch
1981 Nature
Structure and function of telomeres
1991 StandoutNatureNobel
Role of glutamic acid-181 in DNA-sequence recognition by the catabolite gene activator protein (CAP) of Escherichia coli: altered DNA-sequence-recognition properties of [Val181]CAP and [Leu181]CAP.
1987
Diffusion-driven mechanisms of protein translocation on nucleic acids. 1. Models and theory
1981 Standout
An inducible transcription factor activates expression of human immunodeficiency virus in T cells
1987 StandoutNatureNobel
Overlapping elements in the guanylate-binding protein gene promoter mediate transcriptional induction by alpha and gamma interferons.
1991
On the specificity of DNA-protein interactions.
1986
RNA structure
1977
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
DNA-binding site of lac repressor probed by dimethylsulfate methylation of lac operator
1979 StandoutNobel
Works of Arnold Revzin being referenced
Studies of DNA‐protein interactions by gel electrophoresis
1989
Molecular parameters characterizing the interaction of Escherichia coli lac repressor with non-operator DNA and inducer
1977
Interactions of the catabolite activator protein (CAP) at the galactose and lactose promoters of Escherichia coli probed by hydroxyl radical footprinting. The second CAP molecule which binds at gal and the one CAP at lac may act to stimulate transcription in the same way.
1987
Conformation changes in rRNA induced by electric impulses
1974
Stoichiometry of catabolite activator protein/adenosine cyclic 3',5'-monophosphate interactions at the lac promoter of Escherichia coli
1982
Cooperative binding to DNA of catabolite activator protein of Escherichia coli
1979
Non-specific DNA Binding of Genome Regulating Proteins as a Biological Control Mechanism: 1. The lac Operon: Equilibrium Aspects
1974
The Biology of Nonspecific DNA Protein Interactions
1990
Nonspecific DNA binding of genome-regulating proteins as a biological control mechanism: Measurement of DNA-bound Escherichia coli lac repressor in vivo
1977
The binding of catabolite activator protein and RNA polymerase to the Escherichia coli galactose and lactose promoters probed by alkylation interference studies.
1986
Metastable secondary structures in ribosomal RNA: A new method for analyzing the titration behavior of rRNA
1973
Metastable secondary structures in ribosomal RNA molecular hysteresis in the acid-base titration of Escherichia coli ribosomal RNA
1973
Direct measurement of association constants for the binding of Escherichia coli lac repressor to non-operator DNA
1977
Two catabolite activator protein molecules bind to the galactose promoter region of Escherichia coli in the presence of RNA polymerase
1983
Gel electrophoresis assays for DNA-protein interactions.
1989
The light-activated GTP-dependent cyclic GMP phosphodiesterase complex of bovine retinal rod outer segments. Dark resolution of the catalytic and regulatory proteins.
1981
Intracellular location of catabolite activator protein of Escherichia coli
1980
Kinetics of RNA polymerase-promoter complex formation: effects of nonspecific DNA-protein interactions
1984
A gel electrophoresis method for quantifying the binding of proteins to specific DNA regions: application to components of the Escherichia coli lactose operon regulatory system
1981 Standout
Quantitation of the interaction of Escherichia coli RNA polymerase holoenzyme with double-helical DNA using a thermodynamically rigorous centrifugation method
1981
Solutions of RNA polymerase plus linear wild typeE. eoli lacDNA fragments contain a mixture of stable PI and P2 promoter complexes
1986
Comparison of nucleic acid-protein interactions in solution and in polyacrylamide gels
1986
Interaction of catabolite activator protein of Escherichia coli with single-stranded deoxyribonucleic acid
1981
Binding of E.coli lac repressor to non-operator DNA
1977