Standout Papers
Citation Impact
Citing Papers
Complete Genome Sequence of the Ammonia-Oxidizing Bacterium and Obligate Chemolithoautotroph Nitrosomonas europaea
2003
CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes
2007 StandoutScience
Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution
2009 StandoutScienceNobel
Large-scale reconstruction and phylogenetic analysis of metabolic environments
2008
Three RNA cells for ribosomal lineages and three DNA viruses to replicate their genomes: A hypothesis for the origin of cellular domain
2006
One thousand plant transcriptomes and the phylogenomics of green plants
2019 StandoutNature
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions
2021 StandoutNobel
Directed evolution of Vibrio fischeri LuxR for increased sensitivity to a broad spectrum of acyl‐homoserine lactones
2004 StandoutNobel
A DNA repair system specific for thermophilic Archaea and bacteria predicted by genomic context analysis
2002
Impact frustration of the origin of life
1988 Nature
Classification and evolution of type II CRISPR-Cas systems
2014 StandoutNobel
Lateral gene transfer and the nature of bacterial innovation
2000 StandoutNature
Combinatorial and computational challenges for biocatalyst design
2001 StandoutNatureNobel
Phylogenomics and the reconstruction of the tree of life
2005
Ribozymes: aiming at RNA replication and protein synthesis
1996 StandoutNobel
Inferring the historical patterns of biological evolution
1999 StandoutNature
New functions from old scaffolds: How nature reengineers enzymes for new functions
2001
Mineral Surfaces, Geochemical Complexities, and the Origins of Life
2010
Purification of tetrahymena telomerase and cloning of genes encoding the two protein components of the enzyme
1995 StandoutNobel
CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III
2011 StandoutNatureNobel
Complete nitrification by Nitrospira bacteria
2015 StandoutNature
The 2–5 A system: Modulation of viral and cellular processes through acceleration of RNA degradation
1998
The stability of proteins in extreme environments
1998
Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage
2017 StandoutNature
Oligopeptides as catalysts for asymmetric epoxidation
2005
Decoding ALS: from genes to mechanism
2016 StandoutNature
Archaeal genomics
1999
Prokaryotic Evolution in Light of Gene Transfer
2002
Tunicates and not cephalochordates are the closest living relatives of vertebrates
2006 StandoutNature
Manganese‐Substituted Carbonic Anhydrase as a New Peroxidase
2006
Protein design at the interface of the pre-biotic and biotic worlds
2012
Analysis of Phenetic Trees Based on Metabolic Capabilites Across the Three Domains of Life
2004
Polymerase chain reaction in liposomes
1995
Cloning and expression of the essential gene for poly(A) polymerase from S. cerevisiae
1991 Nature
Obcells as Proto-Organisms: Membrane Heredity, Lithophosphorylation, and the Origins of the Genetic Code, the First Cells, and Photosynthesis
2001
Call of the wild: antibiotic resistance genes in natural environments
2010 Standout
Comparative genomics, minimal gene-sets and the last universal common ancestor
2003
Synthesizing life
2001 StandoutNatureNobel
Status of genome projects for nonpathogenic bacteria and archaea
2000
Asymmetric catalysis with peptides
2011
Diversity, stability and resilience of the human gut microbiota
2012 StandoutNature
About Various Definitions of Life
1998
A synthetic multicellular system for programmed pattern formation
2005 StandoutNatureNobel
Template-directed synthesis of a genetic polymer in a model protocell
2008 StandoutNatureNobel
Cations as Mediators of the Adsorption of Nucleic Acids on Clay Surfaces in Prebiotic Environments
2003
Structural Evidence for Evolution of the β/α Barrel Scaffold by Gene Duplication and Fusion
2000 Science
Simple yet functional phosphate-loop proteins
2018 StandoutNobel
Transcript-Assisted Transcriptional Proofreading
2006 Science
Phylogenomics
2005
A Possible Route to Prebiotic Vesicle Reproduction
2004
Complexation of Polyoxometalates with Cyclodextrins
2015 StandoutNobel
The search for the chemistry of life's origin
2007
Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials
2015 Standout
Crystal Structure at 3.5 Å Resolution of HIV-1 Reverse Transcriptase Complexed with an Inhibitor
1992 StandoutScience
Membrane growth can generate a transmembrane pH gradient in fatty acid vesicles
2004 StandoutNobel
Are RNA Viruses Candidate Agents for the Next Global Pandemic? A Review
2017
De novo design of modular protein hydrogels with programmable intra- and extracellular viscoelasticity
2024 StandoutNobel
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
Comparing Photosynthetic and Photovoltaic Efficiencies and Recognizing the Potential for Improvement
2011 StandoutScience
Decoupling function and taxonomy in the global ocean microbiome
2016 StandoutScience
Commensal Host-Bacterial Relationships in the Gut
2001 StandoutScience
Occurrence, Classification, and Biological Function of Hydrogenases: An Overview
2007 Standout
Dynamic Control and Amplification of Molecular Chirality by Circular Polarized Light
1996 StandoutScienceNobel
Cytosine deamination and the precipitous decline of spontaneous mutation during Earth's history
2016
Ion-dependent protein–surface interactions from intrinsic solvent response
2021 StandoutNobel
Coupled Growth and Division of Model Protocell Membranes
2009 StandoutNobel
Osmosensory signaling in Mycobacterium tuberculosis mediated by a eukaryotic-like Ser/Thr protein kinase
2013 StandoutNobel
Specific inhibition of gene expression by small double-stranded RNAs in invertebrate and vertebrate systems
2001 StandoutNobel
Surprising Arginine Biosynthesis: a Reappraisal of the Enzymology and Evolution of the Pathway in Microorganisms
2007
Origin and evolution of retroelements based upon their reverse transcriptase sequences.
1990
Telomerase Catalytic Subunit Homologs from Fission Yeast and Human
1997 StandoutScienceNobel
Emergent properties arising from the assembly of amphiphiles. Artificial vesicle membranes as reaction promoters and regulators
2014
GENOME TREES AND THE NATURE OF GENOME EVOLUTION
2005
Liquid-Liquid Phase Separation in Biology
2014 Standout
A structural view of evolutionary divergence
1999 StandoutNobel
Synthesis of β-Branched Tryptophan Analogues Using an Engineered Subunit of Tryptophan Synthase
2016 StandoutNobel
CRISPR/Cas, the Immune System of Bacteria and Archaea
2010 StandoutScience
The Cinchona Primary Amine-Catalyzed Asymmetric Epoxidation and Hydroperoxidation of α,β-Unsaturated Carbonyl Compounds with Hydrogen Peroxide
2013 StandoutNobel
A Hydrogen-Rich Early Earth Atmosphere
2005 Science
Catalytic Mechanism and Performance of Computationally Designed Enzymes for Kemp Elimination
2008 StandoutNobel
DNA-Based Asymmetric Catalysis: Sequence-Dependent Rate Acceleration and Enantioselectivity
2008 StandoutNobel
Divergent Evolution of Enzymatic Function: Mechanistically Diverse Superfamilies and Functionally Distinct Suprafamilies
2001
Genomics ofActinobacteria: Tracing the Evolutionary History of an Ancient Phylum
2007
The unique biochemistry of methanogenesis
2002
Utilization of ribonucleotides and RNA primers by Tetrahymena telomerase.
1995 StandoutNobel
The Microbial Engines That Drive Earth's Biogeochemical Cycles
2008 StandoutScience
A Phylogenomic Study of Birds Reveals Their Evolutionary History
2008 StandoutScience
Experimental Models of Primitive Cellular Compartments: Encapsulation, Growth, and Division
2003 StandoutScienceNobel
Structural and Kinetic Characterization of an Acyl Transferase Ribozyme
1998 StandoutNobel
Identification of four conserved motifs among the RNA-dependent polymerase encoding elements.
1989
Archaea and the prokaryote-to-eukaryote transition
1997
Thermostability of model protocell membranes
2008 StandoutNobel
Earth's Early Atmosphere
1993 StandoutScience
The role of chirality in the origin of life
1991 Nobel
Complete Genome Sequence of the Marine, Chemolithoautotrophic, Ammonia-Oxidizing Bacterium Nitrosococcus oceani ATCC 19707
2006
Works of Antonio Lazcano being referenced
Primordial synthesis of amines and amino acids in a 1958 Miller H 2 S-rich spark discharge experiment
2011
Polyamino acids as synthetic enzymes: mechanism, applications and relevance to prebiotic catalysis
2005
The origin of life?did it occur at high temperatures?
1995
On the levels of enzymatic substrate specificity: Implications for the early evolution of metabolic pathways
1995
Structural Analysis of Monomeric RNA-Dependent Polymerases: Evolutionary and Therapeutic Implications
2015
On the early evolution of RNA polymerase
1988
How long did it take for life to begin and evolve to cyanobacteria?
1994
Charles Darwin and the Origin of Life
2009
Molecular Evolution of the Lysine Biosynthetic Pathways
2002
Molecular evolution of the histidine biosynthetic pathway
1995
The evolutionary transition from RNA to DNA in early cells
1988
The Origin and Early Evolution of Life: Prebiotic Chemistry, the Pre-RNA World, and Time
1996
Historical Development of Origins Research
2010
THE ORIGIN AND EARLY EVOLUTION OF LIFE ON EARTH
1990
Paralogous histidine biosynthetic genes: evolutionary analysis of the Saccharomyces cerevisiae HIS6 and HIS7 genes
1997
A minimal living system and the origin of a protocell
1984
The roads to and from the RNA world
2003
On the Origin of Metabolic Pathways
1999
Prebiotic Soup--Revisiting the Miller Experiment
2003 Science
Evolution of the Structure and Chromosomal Distribution of Histidine Biosynthetic Genes
1998
The Genomic Tree as Revealed from Whole Proteome Comparisons
1999
Histidine biosynthetic pathway and genes: structure, regulation, and evolution
1996
Some Like It Hot, But Not the First Biomolecules
2002 Science
The molecular search for the last common ancestor
1999
Astrophysical and astrochemical insights into the origin of life
2002
The Miller Volcanic Spark Discharge Experiment
2008 Science
Primitive Earth environments: organic syntheses and the origin and early evolution of life
1983