Citation Impact
Citing Papers
Global phosphorylation analysis of β-arrestin–mediated signaling downstream of a seven transmembrane receptor (7TMR)
2010 StandoutNobel
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
2017 Standout
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
2009 StandoutScience
The C9orf72 protein interacts with Rab1a and the ULK 1 complex to regulate initiation of autophagy
2016
Loss of C9 ORF 72 impairs autophagy and synergizes with polyQ Ataxin‐2 to induce motor neuron dysfunction and cell death
2016
Antisense RNA foci in the motor neurons of C9ORF72-ALS patients are associated with TDP-43 proteinopathy
2015
New approaches to the study of sepsis
2012
Alterations in lysosomal and proteasomal markers in Parkinson's disease: Relationship to alpha-synuclein inclusions
2009
CGG Repeat-Associated Non-AUG Translation Utilizes a Cap-Dependent Scanning Mechanism of Initiation to Produce Toxic Proteins
2016
Limelight on Alpha-Synuclein: Pathological and Mechanistic Implications in Neurodegeneration
2013
Parkinson disease
2017 Standout
Recent advances in our understanding of neurodegeneration
2009
Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of nuclear factor E2-related factor 2 (Nrf2)
2009
Misfolded PrP impairs the UPS by interaction with the 20S proteasome and inhibition of substrate entry
2011
Mechanism and medical implications of mammalian autophagy
2018 Standout
The role of autophagy in neurodegenerative disease
2013 Standout
Cellular strategies for controlling protein aggregation
2010
Oxidative stress, dysfunctional glucose metabolism and Alzheimer disease
2019 Standout
The Roles of PINK1, Parkin, and Mitochondrial Fidelity in Parkinson’s Disease
2015 Standout
C9orf72 BAC Mouse Model with Motor Deficits and Neurodegenerative Features of ALS/FTD
2016
Cancer drug resistance: an evolving paradigm
2013 Standout
Hallmarks of aging: An expanding universe
2023 Standout
A computationally engineered RAS rheostat reveals RAS–ERK signaling dynamics
2016 StandoutNobel
SHP-1 Inhibition by 4-Hydroxynonenal Activates Jun N-Terminal Kinase and Glutamate Cysteine Ligase
2008
Andromeda: A Peptide Search Engine Integrated into the MaxQuant Environment
2011 Standout
O-Pair Search with MetaMorpheus for O-glycopeptide characterization
2020 StandoutNobel
Oxidative stress, neurodegeneration, and the balance of protein degradation and protein synthesis
2012
The biology and function of fibroblasts in cancer
2016 Standout
Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS
2015
p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria
2010
Isotope-targeted glycoproteomics (IsoTaG): a mass-independent platform for intact N- and O-glycopeptide discovery and analysis
2015 StandoutNobel
C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles
2016
Sepsis-induced immunosuppression: from cellular dysfunctions to immunotherapy
2013 Standout
Distribution of dipeptide repeat proteins in cellular models and C9orf72 mutation cases suggests link to transcriptional silencing
2015
Autophagy: Renovation of Cells and Tissues
2011 Standout
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
2021 StandoutNobel
Predictive functional profiling of microbial communities using 16S rRNA marker gene sequences
2013 Standout
Decoding ALS: from genes to mechanism
2016 StandoutNature
GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport
2015 Nature
Structural Basis for Recognizing Phosphoarginine and Evolving Residue-Specific Protein Phosphatases in Gram-Positive Bacteria
2013 StandoutNobel
Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
2019 Standout
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Exploring the link between glucocerebrosidase mutations and parkinsonism
2011
Parkinson's disease
2015 Standout
Widespread Translational Remodeling during Human Neuronal Differentiation
2017 StandoutNobel
Profilin 1 Associates with Stress Granules and ALS-Linked Mutations Alter Stress Granule Dynamics
2014
Quantitative Mass Spectrometry Reveals Dynamics of Factor-inhibiting Hypoxia-inducible Factor-catalyzed Hydroxylation
2011 StandoutNobel
Microfluidic organs-on-chips
2014 Standout
Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies
2015 Nobel
Autophagy in Human Health and Disease
2013 Standout
Mechanisms of mitophagy
2010 Standout
Current Challenges in Vaccinology
2020
Systematic Reviews of Animal Models: Methodology versus Epistemology
2013
The role of tumour–stromal interactions in modifying drug response: challenges and opportunities
2013
Characterization of the dipeptide repeat protein in the molecular pathogenesis of c9FTD/ALS
2014
Distinct RolesIn Vivofor the Ubiquitin–Proteasome System and the Autophagy–Lysosomal Pathway in the Degradation of α-Synuclein
2011
Anti-Vascular Endothelial Growth Factors Protect Retinal Pigment Epithelium Cells Against Oxidation by Modulating Nitric Oxide Release and Autophagy
2017 Standout
Antisense Proline-Arginine RAN Dipeptides Linked to C9ORF72-ALS/FTD Form Toxic Nuclear Aggregates that Initiate In Vitro and In Vivo Neuronal Death
2014
Stimulation of autophagy reduces neurodegeneration in a mouse model of human tauopathy
2012
Alpha-synuclein and Protein Degradation Systems: a Reciprocal Relationship
2012
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTips
2007 Standout
Global, In Vivo, and Site-Specific Phosphorylation Dynamics in Signaling Networks
2006 Standout
The Mechanistic Links Between Proteasome Activity, Aging and Agerelated Diseases
2014
Mouse models of human evolution
2014
The Role of Dipeptide Repeats in C9ORF72-Related ALS-FTD
2017
Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers
2016
Dipeptide repeat protein inclusions are rare in the spinal cord and almost absent from motor neurons in C9ORF72 mutant amyotrophic lateral sclerosis and are unlikely to cause their degeneration
2015
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
2015 StandoutNature
PhosphoSitePlus, 2014: mutations, PTMs and recalibrations
2014 Standout
Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization
2015 Standout
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
The amyloid state and its association with protein misfolding diseases
2014 Standout
Phosphorylation of p62 Activates the Keap1-Nrf2 Pathway during Selective Autophagy
2013
Quantitative analysis and clinico-pathological correlations of different dipeptide repeat protein pathologies in C9ORF72 mutation carriers
2015
The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases
2009
The human microbiome: at the interface of health and disease
2012 Standout
Modeling neurodevelopmental disorder-associated humanAGO1mutations inCaenorhabditis elegansArgonautealg-1
2024 StandoutNobel
The Proteasome and Oxidative Stress in Alzheimer's Disease
2016
The Ubiquitin-Proteasome System in Neurodegeneration
2014
Neurodegenerative Diseases: Expanding the Prion Concept
2015
Does Impairment of the Ubiquitin-Proteasome System or the Autophagy-Lysosome Pathway Predispose Individuals to Neurodegenerative Disorders such as Parkinson's Disease?
2010
What Genetics Tells us About the Causes and Mechanisms of Parkinson's Disease
2011
KEGG: integrating viruses and cellular organisms
2020 Standout
Mice carrying a human GLUD2 gene recapitulate aspects of human transcriptome and metabolome development
2016 StandoutNobel
Microglia Function in the Central Nervous System During Health and Neurodegeneration
2017 Standout
Proteasome dysfunction triggers activation of SKN-1A/Nrf1 by the aspartic protease DDI-1
2016 StandoutNobel
Ubiquitin and Parkinson's disease through the looking glass of genetics
2017
The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis
2018 Standout
Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal
2014 Standout
Plastic and Human Health: A Micro Issue?
2017 Standout
2016
Neuronal‐specific proteasome augmentation via Prosβ5 overexpression extends lifespan and reduces age‐related cognitive decline
2019
Generation and Detection of Reactive Oxygen Species in Photocatalysis
2017 Standout
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
2010 Standout
GGGGCC microsatellite RNA is neuritically localized, induces branching defects, and perturbs transport granule function
2015
Proteostasis Failure in Neurodegenerative Diseases: Focus on Oxidative Stress
2020
2015
Works of Anny Devoy being referenced
C9orf72 repeat expansions cause neurodegeneration in Drosophila through arginine-rich proteins
2014 Science
Genomically humanized mice: technologies and promises
2011
New Zealand's epidemic of meningococcal disease described using molecular analysis: implications for vaccine delivery
2005
The ubiquitin–proteasome system and cancer
2005
Profilin1 E117G is a moderate risk factor for amyotrophic lateral sclerosis
2013
Depletion of 26S Proteasomes in Mouse Brain Neurons Causes Neurodegeneration and Lewy-Like Inclusions Resembling Human Pale Bodies
2008
The ubiquitin–proteasome system and cancer
2005