Citation Impact
Citing Papers
High-throughput characterization of protein–protein interactions by reprogramming yeast mating
2017 StandoutNobel
An engineered 4-1BBL fusion protein with “activity on demand”
2020
Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
2013 Standout
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Crippling life support for SARS-CoV-2 and other viruses through synthetic lethality
2020 StandoutNobel
A completely foreign receptor can mediate an interferon-gamma-like response
2001
Structure and function of lysosomal phospholipase A2: identification of the catalytic triad and the role of cysteine residues
2005
Interleukin-5 binds to heparin/heparan sulfate. A model for an interaction with extracellular matrix
1998
In silico prediction of protein-protein interactions in human macrophages
2014 Standout
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy
2022 StandoutNobel
Functional diversity of helper T lymphocytes
1996 StandoutNature
Conversion of monomeric protein L to an obligate dimer by computational protein design
2001 StandoutNobel
Dendritic cells in cancer immunology and immunotherapy
2019 Standout
Chromatin Reader Brd4 Functions in Ig Class Switching as a Repair Complex Adaptor of Nonhomologous End-Joining
2014 StandoutNobel
Inflammation and metabolic disorders
2006 StandoutNature
Probing cellular protein complexes using single-molecule pull-down
2011 Nature
Two-hybrid technologies in proteomics research
2008
Multifarious Determinants of Cytokine Receptor Signaling Specificity
2014
Effect of Mechanical Ventilation on Inflammatory Mediators in Patients With Acute Respiratory Distress Syndrome
1999 Standout
Mepolizumab and Exacerbations of Refractory Eosinophilic Asthma
2009 Standout
Group XV phospholipase A2, a lysosomal phospholipase A2
2010
Down-modulation of Type 1 Interferon Responses by Receptor Cross-competition for a Shared Jak Kinase
2001
An experimentally derived confidence score for binary protein-protein interactions
2008
Cytokines in asthma
1999
The biology of VEGF and its receptors
2003 Standout
A new high affinity binding site for suppressor of cytokine signaling‐3 on the erythropoietin receptor
2002
Interferon-induced ISG15 pathway: an ongoing virus–host battle
2013
Inflammation, stress, and diabetes
2005 Standout
Receptor-mediated label-transfer assay (RELAY): a novel method for the detection of plasma tumor necrosis factor at attomolar concentrations
1994 StandoutNobel
SHP2 and SOCS3 Contribute to Tyr-759-dependent Attenuation of Interleukin-6 Signaling through gp130
2002
Engineering interferons and interleukins for cancer immunotherapy
2022
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
2006 StandoutNature
Protein-Protein Interactions and Prediction: A Comprehensive Overview
2013
Virus-host interactomics: new insights and opportunities for antiviral drug discovery
2014
Novel bioactive glycerol-based lysophospholipids: New data – New insight into their function
2012
Anti–IL-5 (mepolizumab) therapy induces bone marrow eosinophil maturational arrest and decreases eosinophil progenitors in the bronchial mucosa of atopic asthmatics
2003
The development of allergic inflammation
2008 StandoutNature
Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase
2015
Photoactivable peptides for identifying enzyme–substrate and protein–protein interactions
2010 StandoutNobel
Tuning Cytokine Receptor Signaling by Re-orienting Dimer Geometry with Surrogate Ligands
2015
Asthma
2001 Standout
High efficiency cell-specific targeting of cytokine activity
2014
Mepolizumab Treatment in Patients with Severe Eosinophilic Asthma
2014 Standout
STATs in cancer inflammation and immunity: a leading role for STAT3
2009 Standout
Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3
2004
gp130 receptor ligands as potential therapeutic targets for obesity
2007
Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial
2012 Standout
Ligand-independent Dimerization of the Extracellular Domain of the Leptin Receptor and Determination of the Stoichiometry of Leptin Binding
1997
What We Talk About When We Talk About Fat
2014 Standout
Creation of a biologically active interleukin-5 monomer
1996 Nature
Interferons α and λ Inhibit Hepatitis C Virus Replication With Distinct Signal Transduction and Gene Regulation Kinetics
2006 StandoutNobel
Orientation‐specific signalling by thrombopoietin receptor dimers
2011
Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity
2004
Characterization of the Receptor Binding Sites of Human Leukemia Inhibitory Factor and Creation of Antagonists
1996
Convergent Mechanisms for Recognition of Divergent Cytokines by the Shared Signaling Receptor gp130
2003 StandoutNobel
Leptin and the regulation of body weight in mammals
1998 StandoutNature
A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells
1997 StandoutNature
Eosinophils: Biology and Role in Disease
1995
α and α Interferons and Their Receptor and Their Friends and Relations
1995
Muscle as an Endocrine Organ: Focus on Muscle-Derived Interleukin-6
2008 Standout
Characterization of Recombinant Extracellular Domain of Human Interleukin-10 Receptor
1995
Cytokines in clinical cancer immunotherapy
2018
Neuropilin-1 Is Expressed by Endothelial and Tumor Cells as an Isoform-Specific Receptor for Vascular Endothelial Growth Factor
1998 Standout
Mast cell and eosinophil surface receptors as targets for anti-allergic therapy
2016
Eosinophil's Role Remains Uncertain as Anti–Interleukin-5 only Partially Depletes Numbers in Asthmatic Airway
2003
The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY
2017 Standout
Noninvasive imaging of protein–protein interactions in living animals
2002
Activation of STAT3 by IL-6 and IL-10 in Primary Human Macrophages Is Differentially Modulated by Suppressor of Cytokine Signaling 3
2003
Neanderthal ancestry drives evolution of lipid catabolism in contemporary Europeans
2014 StandoutNobel
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
2003 Standout
HOW CELLS RESPOND TO INTERFERONS
1998 Standout
Interactive Proteomics: What Lies Ahead?
2008
Soluble receptors in human disease
1998
Caspase-1 targets the TLR adaptor Mal at a crucial TIR-domain interaction site
2010
Current State of Imaging Protein-Protein Interactions In Vivo with Genetically Encoded Reporters
2007
Characterization and Mutagenesis of Gal/GlcNAc-6-O-sulfotransferases
2002 StandoutNobel
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
2011 StandoutNobel
Abrogation of the Brd4-Positive Transcription Elongation Factor b Complex by Papillomavirus E2 Protein Contributes to Viral Oncogene Repression
2009
The Role of Suppressors of Cytokine Signaling (SOCS) Proteins in Regulation of the Immune Response
2004
ATP-independent diffusion of double-stranded RNA binding proteins
2012 StandoutNobel
SH2 Domains from Suppressor of Cytokine Signaling-3 and Protein Tyrosine Phosphatase SHP-2 Have Similar Binding Specificities
2002
Carbohydrate Sulfotransferases of the GalNAc/Gal/GlcNAc6ST Family
2002 StandoutNobel
Degradation of the Met Tyrosine Kinase Receptor by the Ubiquitin-Proteasome Pathway
1997 StandoutNobel
Allergy and Allergic Diseases
2001
Bifidobacterium longum supplementation improved high-fat-fed-induced metabolic syndrome and promoted intestinal Reg I gene expression
2011
Interferon-Stimulated Genes: A Complex Web of Host Defenses
2014 StandoutNobel
Suppressor of Cytokine Signaling-3 Is Recruited to the Activated Granulocyte-Colony Stimulating Factor Receptor and Modulates its Signal Transduction
2002
Enhanced Antibacterial Potential in UBP43-Deficient Mice against Salmonella typhimurium Infection by Up-Regulating Type I IFN Signaling
2005 StandoutNobel
Interleukin-10 and the Interleukin-10 Receptor
2001 Standout
Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor.
1993
STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
2018 Standout
Imaging Tri-Fusion Multimodality Reporter Gene Expression in Living Subjects
2004 StandoutNobel
Imaging the glycome
2008 StandoutNobel
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
Soluble receptors for cytokines and growth factors: generation and biological function
1994
Leptin's Role in Lipodystrophic and Nonlipodystrophic Insulin-Resistant and Diabetic Individuals
2013
Role of the Vascular Endothelial Growth Factor Pathway in Tumor Growth and Angiogenesis
2004 Standout
CASTp 3.0: computed atlas of surface topography of proteins
2018 Standout
Cytokine structural taxonomy and mechanisms of receptor engagement
1993
Works of Annick Verhee being referenced
Delivering Type I Interferon to Dendritic Cells Empowers Tumor Eradication and Immune Combination Treatments
2017
Relationship between structure and biochemical phenotype of lecithin:cholesterol acyltransferase (LCAT) mutants causing fish-eye disease
2000
Safe eradication of large established tumors using neovasculature‐targeted tumor necrosis factor‐based therapies
2020
Dimerization of the Interferon Type I Receptor IFNaR2–2 Is Sufficient for Induction of Interferon Effector Genes but Not for Full Antiviral Activity
1999
A proposed architecture for lecithin cholesterol acyl transferase (LCAT): Identification of the catalytic triad and molecular modeling
1998
Design and application of a cytokine-receptor-based interaction trap
2001
Reverse MAPPIT: screening for protein-protein interaction modifiers in mammalian cells
2005
Identification of the Y985 and Y1077 motifs as SOCS3 recruitment sites in the murine leptin receptor
2000
Characterization of functional residues in the interfacial recognition domain of lecithin cholesterol acyltransferase (LCAT)
1999
HyperISGylation of Old World Monkey ISG15 in Human Cells
2008
Headgroup specificity of lecithin cholesterol acyltransferase for monomeric and vesicular phospholipids
2000
The cell surface expression level of the human interleukin‐5 receptor α subunit determines the agonistic/antagonistic balance of the human interleukin‐5 E13Q mutein
1999
Analysis of Tyr to Phe and fa/fa leptin receptor mutations in the PC12 cell line.
1999
Identification and expression analysis of leptin-regulated immediate early response and late target genes
2000
Interleukin 5 regulates the isoform expression of its own receptor α-subunit
2000
Comparison of leptin- and interleukin-6-regulated expression of the rPAP gene family: evidence for differential co-regulatory signals.
2002
Mammalian Protein-Protein Interaction Trap (MAPPIT) Analysis of STAT5, CIS, and SOCS2 Interactions with the Growth Hormone Receptor
2007
Selection of non-competitive leptin antagonists using a random nanobody-based approach
2011
Recombinant soluble human interleukin-5 (hIL-5) receptor molecules. Cross-linking and stoichiometry of binding to IL-5.
1993
Molecular basis of the membrane-anchored and two soluble isoforms of the human interleukin 5 receptor alpha subunit.
1992
Identification of receptor-binding domains on human interleukin 5 and design of an interleukin 5-derived receptor antagonist.
1995
A safe and highly efficient tumor-targeted type I interferon immunotherapy depends on the tumor microenvironment
2017