Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
A Network of Control Mediated by Regulator of Calcium/Calmodulin-Dependent Signaling
2004 Science
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
MutL traps MutS at a DNA mismatch
2015 StandoutNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
A possible mechanism for exonuclease 1-independent eukaryotic mismatch repair
2009 StandoutNobel
Protein roadblocks and helix discontinuities are barriers to the initiation of mismatch repair
2007 StandoutNobel
Soluble expression of proteins correlates with a lack of positively-charged surface
2013
The DNA-damage response in human biology and disease
2009 StandoutNature
A stomatin-like protein necessary for mechanosensation in C. elegans
1995 StandoutNatureNobel
(CAG)n-hairpin DNA binds to Msh2–Msh3 and changes properties of mismatch recognition
2005
Intracellular antibodies and challenges facing their use as therapeutic agents
2003
A New Monoclonal Antibody Which Selectively Recognizes the Active Form of Src Tyrosine Kinase
1996
Discoveries in structure and physiology of mechanically activated ion channels
2020 StandoutNatureNobel
Incision-dependent and error-free repair of (CAG)n/(CTG)n hairpins in human cell extracts
2009
Targeted Disruption of the Cln3 Gene Provides a Mouse Model for Batten Disease
1999
Somatic expansion behaviour of the (CTG)n repeat in myotonic dystrophy knock-in mice is differentially affected by Msh3 and Msh6 mismatch-repair proteins
2002
Pms2 is a genetic enhancer of trinucleotide CAG{middle dot}CTG repeat somatic mosaicism: implications for the mechanism of triplet repeat expansion
2004
Transgenic mice carrying large human genomic sequences with expanded CTG repeat mimic closely the DM CTG repeat intergenerational and somatic instability
2000
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
Slipped-strand DNAs formed by long (CAG)middle dot(CTG) repeats: slipped-out repeats and slip-out junctions
2002
Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins
1994 StandoutNobel
Genetically Encodable Fluorescent Biosensors for Tracking Signaling Dynamics in Living Cells
2011
Endonucleolytic Function of MutLα in Human Mismatch Repair
2006 StandoutNobel
Expandable DNA repeats and human disease
2007 Nature
The multifaceted mismatch-repair system
2006
MSH2 ATPase Domain Mutation Affects CTG•CAG Repeat Instability in Transgenic Mice
2009
Gene interactions affecting mechanosensory transduction in Caenorhabditis elegans
1994 StandoutNatureNobel
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
2006 StandoutNature
Dramatic mutation instability in HD mouse striatum: does polyglutamine load contribute to cell-specific vulnerability in Huntington's disease?
2000
Gene targeting of BPAG1: Abnormalities in mechanical strength and cell migration in stratified epithelia and neurologic degeneration
1995
CTG repeat instability and size variation timing in DNA repair-deficient mice
2003
The mechanosensory protein MEC-6 is a subunit of the C. elegans touch-cell degenerin channel
2002 StandoutNatureNobel
Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: A mouse model of amyotrophic lateral sclerosis
1993
A Computationally Designed Inhibitor of an Epstein-Barr Viral Bcl-2 Protein Induces Apoptosis in Infected Cells
2014 StandoutNobel
A Protein-Tagging System for Signal Amplification in Gene Expression and Fluorescence Imaging
2014
A potassium channel mutation in weaver mice implicates membrane excitability in granule cell differentiation
1995
OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells
2007 Nature
De novo design of a fluorescence-activating β-barrel
2018 StandoutNatureNobel
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
MEC-2 regulates C. elegans DEG/ENaC channels needed for mechanosensation
2002 StandoutNatureNobel
Isolating and engineering human antibodies using yeast surface display
2006
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Features of trinucleotide repeat instability in vivo
2008
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
The mec-4 gene is a member of a family of Caenorhabditis elegans genes that can mutate to induce neuronal degeneration
1991 StandoutNatureNobel
High levels of somatic DNA diversity at the myotonic dystrophy type 1 locus are driven by ultra-frequent expansion and contraction mutations
2012
Molecular genetics of cell death in the nematode Caenorhabditis elegans
1992
Mechanisms of trinucleotide repeat instability during human development
2010
Controlling protein assembly on inorganic crystals through designed protein interfaces
2019 StandoutNatureNobel
Non-B DNA structure-induced genetic instability and evolution
2009
Computational design of ligand-binding proteins with high affinity and selectivity
2013 StandoutNatureNobel
Mechanisms and functions of DNA mismatch repair
2007
DNA mismatch repair: Molecular mechanism, cancer, and ageing
2008
Selective Neuronal Degeneration in Huntington's Disease
2006
C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2
1994 StandoutNobel
Manufacturing Immunity to Disease in a Test Tube: The Magic Bullet Realized
2006
Inhibition of Papillomavirus Protein Function in Cervical Cancer Cells by Intrabody Targeting
2005 StandoutNobel
PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair
2010 StandoutNobel
DNA instability in postmitotic neurons
2008
Computational design of a synthetic PD-1 agonist
2021 StandoutNobel
Sustained elevation of extracellular dopamine causes motor dysfunction and selective degeneration of striatal GABAergic neurons
2003
Acid potentiation of the capsaicin receptor determined by a key extracellular site
2000 StandoutNobel
Mechanisms of transcriptional dysregulation in Huntington's disease
2003
Computation-Guided Backbone Grafting of a Discontinuous Motif onto a Protein Scaffold
2011 StandoutScienceNobel
Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes
2012 StandoutNobel
Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
2013 StandoutScienceNobel
β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes
1999 StandoutScienceNobel
Decrease in topoisomerase I is responsible for activation-induced cytidine deaminase (AID)-dependent somatic hypermutation
2011 StandoutNobel
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
2022 StandoutNobel
Spatial distribution of calcium channels and cytosolic calcium transients in growth cones and cell bodies of sympathetic neurons.
1988 StandoutNobel
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Localization of MMR proteins on meiotic chromosomes in mice indicates distinct functions during prophase I
2005
Wound Healing--Aiming for Perfect Skin Regeneration
1997 StandoutScience
PMS2 endonuclease activity has distinct biological functions and is essential for genome maintenance
2010 StandoutNobel
The NMR–Rosetta capsid model of M13 bacteriophage reveals a quadrupled hydrophobic packing epitope
2015 StandoutNobel
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Genetically targeted cell disruption in Caenorhabditis elegans
1997 StandoutNobel
Quantitative Analysis of the Purkinje Cell and the Granule Cell Populations in the Cerebellum ofNudeMice
1995
Flip and Flop: A Cell-Specific Functional Switch in Glutamate-Operated Channels of the CNS
1990 StandoutScienceNobel
Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin
2011 StandoutScienceNobel
Noise and single channels activated by excitatory amino acids in rat cerebellar granule neurones.
1988
Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation
2013 StandoutNobel
The Mating of a Fly
1994 StandoutScienceNobel
Brain voltage-sensitive calcium channel subtypes differentiated by omega-conotoxin fraction GVIA.
1986
Computational design of a pH-sensitive IgG binding protein
2013 StandoutNobel
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
Filamentous Phage Display in the New Millennium
2005
Works of Anne Messer being referenced
Tonic/clonic seizures in a mouse mutant carrying the weaver gene
1989
Development of a Human Light Chain Variable Domain (VL) Intracellular Antibody Specific for the Amino Terminus of Huntingtin via Yeast Surface Display
2004
Instability of the CAG repeat in immortalized fibroblast cell cultures from Huntington's Disease transgenic mice1Published on the World Wide Web on 15 April 1999.1
1999
An Early-Onset Congenic Strain of themotor neuron degeneration (mnd)Mouse
1999
Changes in the pattern of expression of pp60c‐src in cerebellar mutants of mice
1987
Peripheral macrophage abnormalities in mutant mice with spinocerebellar degeneration
1992
Msh2 deficiency prevents in vivo somatic instability of the CAG repeat in Huntington disease transgenic mice
1999
Physico-chemical determinants of soluble intrabody expression in mammalian cell cytoplasm
2010
The neuronal ceroid lipofuscinoses in human EPMR and mnd mutant mice are associated with mutations in CLN8
1999
Neurofilament Distribution is Altered in the Mnd (Motor Neuron Degeneration) Mouse
1991
Mapping of the motor neuron degeneration (Mnd) gene, a mouse model of amyotrophic lateral sclerosis (ALS)
1992
Histopathology of the late-onset motor neuron degeneration (Mnd) mutant in the mouse
1987
An allele of the mouse mutant dystonia musculorum exhibits lesions in red nucleus and striatum
1980
Human single-chain Fv intrabodies counteract in situ huntingtin aggregation in cellular models of Huntington's disease
2001
Apparent Loss and Hypertrophy of Interneurons in a Mouse Model of Neuronal Ceroid Lipofuscinosis: Evidence for Partial Response to Insulin-Like Growth Factor-1 Treatment
1999
Growth of dissociated rat cerebellar cells using serum-free supplemented media and varied transferrin concentrations
1981
Histopathology of the late-onset motor neuron degeneration (Mnd) mutant in the mouse
1987
Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice
2000
The maintenance and identification of mouse cerebellar granule cells in monolayer culture
1977
Autosomal Dominance in a Late-Onset Motor Neuron Disease in the Mouse
1986