Standout Papers
Citation Impact
Citing Papers
Loss of cryptochrome reduces cancer risk in p53 mutant mice
2009 StandoutNobel
TOR Signaling in Growth and Metabolism
2006 Standout
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
CRY, a Drosophila Clock and Light-Regulated Cryptochrome, Is a Major Contributor to Circadian Rhythm Resetting and Photosensitivity
1998 StandoutNobel
CYCLE Is a Second bHLH-PAS Clock Protein Essential for Circadian Rhythmicity and Transcription of Drosophila period and timeless
1998 StandoutNobel
The functional loss of the retinoblastoma tumour suppressor is a common event in basal-like and luminal B breast carcinomas
2008
Hallmarks of Cancer: The Next Generation
2011 Standout
Mapping of DNA amplifications at 15 chromosomal localizations in 1875 breast tumors: definition of phenotypic groups.
1997
Molecular characterization and chromosomal localization of a third alpha-class hypoxia inducible factor subunit, HIF3alpha.
1998
Detection of DNA amplification in 17 primary breast carcinomas with homogeneously staining regions by a modified comparative genomic hybridization technique
1994
The p38 MAPK stress pathway as a tumor suppressor or more?
2008
Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1
1997
Genome-wide analysis of DNA copy-number changes using cDNA microarrays
1999
Oncogenic properties of PPM1D located within a breast cancer amplification epicenter at 17q23
2002
PIK3CA is implicated as an oncogene in ovarian cancer
1999
Minimal regions of chromosomal imbalance in retinoblastoma detected by comparative genomic hybridization
2001
Identification of S6 Kinase 1 as a Novel Mammalian Target of Rapamycin (mTOR)-phosphorylating Kinase
2005
Signal integration by JNK and p38 MAPK pathways in cancer development
2009 Standout
The mTOR pathway and its role in human genetic diseases
2008
The pathways to tumor suppression via route p38
2007
Lineage-Specific Gene Duplication and Loss in Human and Great Ape Evolution
2004
Mechanism of p38 MAP kinase activation in vivo
2003
A genome-wide comparison of recent chimpanzee and human segmental duplications
2005 StandoutNatureNobel
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
2007 StandoutNobel
Fluorescent labels for proteomics and genomics
2006
A new mathematical model for relative quantification in real-time RT-PCR
2001 Standout
The phosphatidylinositol 3-Kinase–AKT pathway in human cancer
2002 Standout
A Mutant Drosophila Homolog of Mammalian Clock Disrupts Circadian Rhythms and Transcription of period and timeless
1998 StandoutNobel
A novel amplification target, DUSP26, promotes anaplastic thyroid cancer cell growth by inhibiting p38 MAPK activity
2006
When Checkpoints Fail
1997 StandoutNobel
Role of mitogen-activated protein kinase kinase 4 in cancer
2007
The Hallmarks of Cancer
2000 Standout
Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer
2009
Derivation of Embryonic Stem-Cell Lines from Human Blastocysts
2004
A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1
2011 StandoutNatureNobel
Mechanisms of carcinogenesis and the mutant mouse
1996
High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays
1998 Standout
Circular binary segmentation for the analysis of array-based DNA copy number data
2004
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
In situ analyses of genome instability in breast cancer
2004
Breast cancer genomes — form and function
2010
Tissue microarrays for high-throughput molecular profiling of tumor specimens
1998 Standout
Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN
1998 StandoutNobel
Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene‐expression subtypes of breast cancer
2006
Carcinoma-associated fibroblasts stimulate tumor progression of initiated human epithelium
2000
Biological and Molecular Heterogeneity of Breast Cancers Correlates with Their Cancer Stem Cell Content
2010
p38 MAP-Kinases pathway regulation, function and role in human diseases
2007
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
2017 StandoutNobel
Retention of wild-type p53 in tumors from p53 heterozygous mice: reduction of p53 dosage can promote cancer formation
1998
PRAK Is Essential for ras-Induced Senescence and Tumor Suppression
2007
Inactivation of the Wip1 phosphatase inhibits mammary tumorigenesis through p38 MAPK–mediated activation of the p16Ink4a-p19Arf pathway
2004
Molecular genetics of prostate cancer
2000
The role of the MKK6/p38 MAPK pathway in Wip1-dependent regulation of ErbB2-driven mammary gland tumorigenesis
2006
Parallel progression of primary tumours and metastases
2009
Specific patterns of chromosomal abnormalities are associated with RER status in sporadic colorectal cancer
2000
[12] DNA arrays for analysis of gene expression
1999
Live or let die: the cell's response to p53
2002 Standout
Mutational Heterogeneity in Human Cancers: Origin and Consequences
2009
Molecular portraits of human breast tumours
2000 StandoutNature
p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis
1999 StandoutNobel
p38α MAP Kinase as a Sensor of Reactive Oxygen Species in Tumorigenesis
2007
Atherosclerosis — An Inflammatory Disease
1999 Standout
Expression Profile of Ectopic Olfactory Receptors Determined by Deep Sequencing
2013
p38α and p38δ mitogen-activated protein kinase isoforms regulate invasion and growth of head and neck squamous carcinoma cells
2007
Identification of cryptic sites of DNA sequence amplification in human breast cancer by chromosome microdissection
1994
p38 MAP Kinase's Emerging Role as a Tumor Suppressor
2004
Relative quantification of 40 nucleic acid sequences by multiplex ligation-dependent probe amplification
2002 Standout
Vaginal transmission of cell-associated HIV-1 in the mouse is blocked by a topical, membrane-modifying agent
2002
Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells
2001
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
2016 StandoutNobel
RIGUI, a Putative Mammalian Ortholog of the Drosophila period Gene
1997
Why the Rat-1 Fibroblast Should Replace the SCN as the In Vitro Model of Choice
1998 StandoutNobel
Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring
1999 StandoutScience
A specific subdomain in φ29 DNA polymerase confers both processivity and strand-displacement capacity
2005 StandoutNobel
Preservation of light signaling to the suprachiasmatic nucleus in vitamin A-deficient mice
2001 StandoutNobel
Interphase cytogenetics and its role in molecular diagnostics of solid tumors.
1998
The LightCycler TM : A Microvolume Multisample Fluorimeter with Rapid Temperature Control
1997
Fluorescence intermittency in single cadmium selenide nanocrystals
1996 StandoutNatureNobel
Mice with mutations of Dock7 have generalized hypopigmentation and white-spotting but show normal neurological function
2009 StandoutNobel
Frequent inactivation of PTEN/MMAC1 in primary prostate cancer.
1997
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Molecular coevolution within a Drosophila clock gene
1998 StandoutNobel
Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability.
1995
E2A Deficiency Leads to Abnormalities in αβ T-Cell Development and to Rapid Development of T-Cell Lymphomas
1997
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling
2007 StandoutNobel
Vaginal transmission of cell-associated HIV-1 in the mouse is blocked by a topical, membrane-modifying agent
2002
AACR Centennial Series: The Biology of Cancer Metastasis: Historical Perspective
2010
Accurate quantitation of protein expression and site-specific phosphorylation
1999
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
2003 StandoutNobel
A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation
2001 StandoutNobel
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
The Fluorescent Toolbox for Assessing Protein Location and Function
2006 StandoutScienceNobel
A DNA microarray system for analyzing complex DNA samples using two-color fluorescent probe hybridization.
1996
Vitamin B 2 -based blue-light photoreceptors in the retinohypothalamic tract as the photoactive pigments for setting the circadian clock in mammals
1998 StandoutNobel
High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6
2001 StandoutNobel
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation
2012 StandoutNobel
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Role of Mouse Cryptochrome Blue-Light Photoreceptor in Circadian Photoresponses
1998 StandoutScienceNobel
Comprehensive human genome amplification using multiple displacement amplification
2002
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
Discovery of sulfated metabolites in mycobacteria with a genetic and mass spectrometric approach
2002 StandoutNobel
Prospects for the Future
2002 StandoutScienceNobel
Multicolor Spectral Karyotyping of Human Chromosomes
1996 Science
Recombination signal sequence-binding protein Jκ alters mesodermal cell fate decisions by suppressing cardiomyogenesis
2003 StandoutNobel
Spectral karyotyping suggests additional subsets of colorectal cancers characterized by pattern of chromosome rearrangement
2001
Works of Anne Kallioniemi being referenced
ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization.
1992
Analysis of BMP4 and BMP7 signaling in breast cancer cells unveils time-dependent transcription patterns and highlights a common synexpression group of genes
2011
Genome screening by comparative genomic hybridization
1997
A physical map of chromosome 20 established using fluorescence in situ hybridization and digital image analysis
1995
Molecular Cytogenetics of Human Breast Cancer
1994
Increased copy number at 17q22-q24 by CGH in breast cancer is due to high-level amplification of two separate regions
1997
CGH-Plotter: MATLAB toolbox for CGH-data analysis
2003
Detection of retinoblastoma gene copy number in metaphase chromosomes and interphase nuclei by fluorescence in situ hybridization
1992
Physical Mapping of Chromosome 17 Cosmids by Fluorescence in Situ Hybridization and Digital Image Analysis
1994
Molecular cytogenetic analysis of 11 new breast cancer cell lines
1999
Improved technique for analysis of formalin‐fixed, paraffin‐embedded tumors by fluorescence in situ hybridization
1994
High-Throughput Copy Number Analysis of 17q23 in 3520 Tissue Specimens by Fluorescence in Situ Hybridization to Tissue Microarrays
2002
Detecting Activation of Ribosomal Protein S6 Kinase by Complementary DNA and Tissue Microarray Analysis
2000
Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors
1994
Amplification of PPM1D in human tumors abrogates p53 tumor-suppressor activity
2002
The serine-threonine protein phosphatase PPM1D is frequently activated through amplification in aggressive primary breast tumours
2005
Computer image analysis of comparative genomic hybridization
1995
Molecular cytogenetics of primary breast cancer by CGH
1998
Comparative Genomic Hybridization for Molecular Cytogenetic Analysis of Solid Tumors
1992 StandoutScience
Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization.
1994
Comparative genomic hybridization: a rapid new method for detecting and mapping DNA amplification in tumors.
1993
Independent amplification and frequent co-amplification of three nonsyntenic regions on the long arm of chromosome 20 in human breast cancer.
1996
Genetic heterogeneity and clonal evolution underlying development of asynchronous metastasis in human breast cancer.
1997
Multiple genes at 17q23 undergo amplification and overexpression in breast cancer.
2000
New amplified and highly expressed genes discovered in the ERBB2 amplicon in breast cancer by cDNA microarrays.
2001
New insights into testicular germ cell tumorigenesis from gene expression profiling.
2002
Genetic changes in primary and recurrent prostate cancer by comparative genomic hybridization.
1995
Amplification of chromosomal region 20q13 in invasive breast cancer: prognostic implications.
1995
Comprehensive copy number and gene expression profiling of the 17q23 amplicon in human breast cancer
2001
Increased copy number at 20q13 in breast cancer: defining the critical region and exclusion of candidate genes.
1994