Citation Impact
Citing Papers
In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2
2004 StandoutScience
The AKT-mTOR pathway plays a critical role in the development of leiomyosarcomas
2007 Standout
Cytogenetic evidence that circulating epithelial cells in patients with carcinoma are malignant.
2002
Prognostic value of genomic alterations in minimal residual cancer cells purified from the blood of breast cancer patients
2000
Analysis of 148 kb of Genomic DNA Around thewnt1Locus ofFugu rubripes
1999 StandoutNobel
Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: implications for alveolar rhabdomyosarcoma cell of origin
2004 StandoutNobel
p53 mediated death of cells overexpressing MDM2 by an inhibitor of MDM2 interaction with p53
1999
CDK inhibitors: positive and negative regulators of G1-phase progression
1999 Standout
The p16INK4a/CDKN2A tumor suppressor and its relatives
1998
mTOR Signaling in Growth Control and Disease
2012 Standout
MYCN Is the only highly expressed gene from the core amplified domain in human neuroblastomas
1998
TIGAR, a p53-Inducible Regulator of Glycolysis and Apoptosis
2006 Standout
Overexpression of a DEAD Box Protein (DDX1) in Neuroblastoma and Retinoblastoma Cell Lines
1998
p53-Mdm2--the affair that never ends
2002
Synergism between INK4a/ARF inactivation and aberrant HGF/SF signaling in rhabdomyosarcomagenesis
2002
Detailed molecular analysis of 1p36 in neuroblastoma
2001
Role of the SCFSkp2 Ubiquitin Ligase in the Degradation of p21Cip1 in S Phase
2003 StandoutNobel
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Cancer Metastasis: Building a Framework
2006 Standout
Neocentromeres: Role in Human Disease, Evolution, and Centromere Study
2002
The tumor suppressor microRNA let-7 represses the HMGA2 oncogene
2007
Head and neck cancer
2008 Standout
Cellular Senescence in Cancer and Aging
2007 Standout
A New Role for Hypoxia in Tumor Progression
1998
Neuroblastoma: biological insights into a clinical enigma
2003 Standout
DETECTION OF DISSEMINATED TUMOR CELLS IN PERIPHERAL BLOOD
2005
HIF-1α Induces Genetic Instability by Transcriptionally Downregulating MutSα Expression
2005 StandoutNobel
Telomere Shortening and Tumor Formation by Mouse Cells Lacking Telomerase RNA
1997 StandoutNobel
Circulating Tumor Cells, Disease Progression, and Survival in Metastatic Breast Cancer
2004 Standout
Soft-Tissue Sarcomas in Adults
2005 Standout
A Genome-wide RNAi Screen for Modifiers of the Circadian Clock in Human Cells
2009
Isolation of rare circulating tumour cells in cancer patients by microchip technology
2007 StandoutNature
Incidence patterns of soft tissue sarcomas, regardless of primary site, in the surveillance, epidemiology and end results program, 1978–2001: An analysis of 26,758 cases
2006 Standout
Role of the retinoblastoma protein in the pathogenesis of human cancer.
1997 StandoutNobel
Significance, detection and markers of disseminated breast cancer cells
2006
Detection and Clinical Importance of Micrometastatic Disease
1999
Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function
2004 StandoutNobel
Novel Recurrent Genetic Imbalances in Human Hepatocellular Carcinoma Cell Lines Identified by Comparative Genomic Hybridization
1999
Epithelial–mesenchymal transitions in tumour progression
2002 Standout
Blinded by the Light: The Growing Complexity of p53
2009 Standout
The antioxidant function of the p53 tumor suppressor
2005
Fluorescence in situ hybridization analyses of chromosome band 1p36 in neuroblastoma detect two classes of alterations
2002
Effects of cyclooxygenase inhibition on bone, tendon, and ligament healing
2005
Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants
2005 StandoutNatureNobel
Genomic Organization of the OS-9 Gene Amplified in Human Sarcomas
1997
OS-9 Interacts with Hypoxia-Inducible Factor 1α and Prolyl Hydroxylases to Promote Oxygen-Dependent Degradation of HIF-1α
2005 StandoutNobel
Ankylosing spondylitis
2007 Standout
Distinct Sets of Genetic Alterations in Melanoma
2005 Standout
High‐resolution detection and mapping of genomic DNA alterations in neuroblastoma
2005
Genetic heterogeneity of neuroblastoma studied by comparative genomic hybridization
1998
Mechanisms of sarcoma development
2003
Loss of DNA copy number of 10q is associated with aggressive behavior of leiomyosarcomas: a comparative genomic hybridization study
2005
p16(MTS-1/CDKN2/INK4a) in Cancer Progression
2001
Oncomirs — microRNAs with a role in cancer
2006 Standout
The MDM2 gene amplification database
1998
Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a
1997 Standout
A small synthetic peptide, which inhibits the p53-hdm2 interaction, stimulates the p53 pathway in tumour cell lines 1 1Edited by A. R. Fersht
2000
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
Programmed Cell Senescence during Mammalian Embryonic Development
2013 Standout
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
2002 Standout
Twelve amplified and expressed genes localized in a single domain in glioma
1996
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
2014 StandoutNobel
Neuroblastoma
2007 Standout
Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4aΔ2/3 Cancer-Prone Mouse
1999 StandoutNobel
The role of senescent cells in ageing
2014 StandoutNature
let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells
2007 Standout
A microRNA polycistron as a potential human oncogene
2005 StandoutNature
Regulating the p53 pathway: in vitro hypotheses, in vivo veritas
2006
A coding-independent function of gene and pseudogene mRNAs regulates tumour biology
2010 StandoutNature
p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling
2008
Design of a synthetic Mdm2-binding mini protein that activates the p53 response in vivo
1997
Role of the INK4a Locus in Tumor Suppression and Cell Mortality
1996
A Novel Role for High-Mobility Group A Proteins in Cellular Senescence and Heterochromatin Formation
2006
Identification of Cyclobutane Pyrimidine Dimer-Responsive Genes Using UVB-Irradiated Human Keratinocytes Transfected with In Vitro-Synthesized Photolyase mRNA
2015 StandoutNobel
Identification of a 1-megabase consensus region of deletion at 1p36.3 in primary neuroblastomas
2000
The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator
2012 StandoutNobel
Genetic Alterations of Cyclins, Cyclin-Dependent Kinases, and Cdk Inhibitors in Human Cancer
1996
Gains of 13q are correlated with a poor prognosis in liposarcoma
2004
Transfection-Mediated Cell-Cycle Signaling: Considerations for Transient Transfection-Based Cell-Cycle Studies
1999
Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells
2001 StandoutNobel
Ubiquitination of p53 and p21 Is Differentially Affected by Ionizing and UV Radiation
1997
The Protein Kinase Complement of the Human Genome
2002 StandoutScience
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Cancer Cell Cycles
1996 StandoutScience
Molecular Genetics and Cytogenetics of Sarcomas
1995
Comparative genomic hybridization study of primary neuroblastoma tumors. United Kingdom Children's Cancer Study Group.
1997
Control of stem cell self-renewal and differentiation by the heterochronic genes and the cellular asymmetry machinery in Caenorhabditis elegans
2015 StandoutNobel
Molecular Biology of Neuroblastoma
1999
DNA copy number amplifications in human neoplasms: review of comparative genomic hybridization studies.
1998
Homozygous deletion of CDKN2A (p16INK4a/p14ARF) but not within 1p36 or at other tumor suppressor loci in neuroblastoma.
2001
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
2003 StandoutNobel
The cyclin D1 gene is a target of the β-catenin/LEF-1 pathway
1999 Standout
Structural Dynamics of Eukaryotic Chromosome Evolution
2003 StandoutScience
A novel and consistent amplicon at 13q31 associated with alveolar rhabdomyosarcoma
2000
Comparative genomic hybridization study of primary neuroblastoma tumors
1997
THE UBIQUITIN SYSTEM
1998 StandoutNobel
Cyclin D-CDK Subunit Arrangement Is Dependent on the Availability of Competing INK4 and p21 Class Inhibitors
1999
Works of Anne Forus being referenced
A well-differentiated liposarcoma with a new type of chromosome 12-derived markers
2001
Complex composition and co‐amplification of SAS and MDM2 in ring and giant rod marker chromosomes in well‐differentiated liposarcoma
1994
A physical map of a 1.3-Mb region on the long arm of chromosome 12, spanning the GLI and LRP loci
1992
Positional cloning identifies a novel cyclophilin as a candidate amplified oncogene in 1q21
2002
Comparative genomic hybridization analysis of human sarcomas: II. Identification of novel amplicons at 6p and 17p in osteosarcomas
1995
Identification of two distinct chromosome 12-derived amplification units in neuroblastoma cell line NGP
1995
Report of the fifth international workshop on human chromosome 1 mapping 1999
1999
HMGIC, the gene for an architectural transcription factor, is amplified and rearranged in a subset of human sarcomas
1997
The protooncogene CHOP/GADD153, involved in growth arrest and DNA damage response, is amplified in a subset of human sarcomas
1994
Amplification of chromosome subregion 12p11.2–p12.1 in a metastasis of an I(12p)-negative seminoma: Relationship to tumor progression?
1994
Homozygous deletion frequency and expression levels of the CDKN2 gene in human sarcomas - relationship to amplification and mRNA levels of CDK4 and CCND1
1995
Dedifferentiation of a well-differentiated liposarcoma to a highly malignant metastatic osteosarcoma:
2001
Recurrent gains of 1q, 8 and 12 in the Ewing family of tumours by comparative genomic hybridization
1997
Comparative genomic hybridization as a tool to define two distinct chromosome 12‐derived amplification units in well‐differentiated liposarcomas
1994
Molecular characterization of a novel amplicon at 1q21-q22 frequently observed in human sarcomas
1998
Characterization of centromere alterations in liposarcomas
2000
Ectopic expression of target genes may represent an inherent limitation of RT-PCR assays used for micrometastasis detection: studies on the epithelial glycoprotein geneEGP-2
1997
Sensitive fluorescent in situ hybridisation method for the characterisation of breast cancer cells in bone marrow aspirates.
1999
Characterisation of a novel amplicon at 1q21-q22 in human sarcomas by CGH and molecular analysis
1996
Structure of the supernumerary ring and giant rod chromosomes in adipose tissue tumors
1999
Cyclooxygenase-2 Expression in Pediatric Sarcomas
2002
MDM2 Gene Amplification and Transcript Levels in Human Sarcomas: Relationship to TP53 Gene Status
1994
Ectopic expression of target genes may represent an inherent limitation of RT‐PCR assays used for micrometastasis detection: studies on the epithelial glycoprotein gene EGP‐2
1997
Mapping of amplification units in the q13-14 region of chromosome 12 in human sarcomas: some amplica do not include MDM2.
1993