Citation Impact
Citing Papers
Catalytic asymmetric synthesis of new halogenated chiral synthons
1997 StandoutNobel
Covalent inhibitors of glycosidases and their applications in biochemistry and biology
2008
A mechanism-based affinity-labeling agent for possible use in isolating N-acetylglucosaminidase
2001
Purine nucleoside phosphorylases: properties, functions, and clinical aspects
2000
Signals from the lysosome: a control centre for cellular clearance and energy metabolism
2013 Standout
Induced-fit catalysis of corannulene bowl-to-bowl inversion
2014 StandoutNobel
2-Nitro and 4-nitro-quinone-methides are not irreversible inhibitors of bovine β-glucuronidase
2001
Catalytic asymmetric conjugate addition of dialkylzinc reagents to α,β-unsaturated sulfones
2009 StandoutNobel
The endocytic pathway in microglia during health, aging and Alzheimer’s disease
2016
Understanding organofluorine chemistry. An introduction to the C–F bond
2007 Standout
Aβ Oligomers – a decade of discovery
2007 Standout
Selection and evolution of enzymes from a partially randomized non-catalytic scaffold
2007 StandoutNatureNobel
Cu‐Catalyzed Asymmetric Allylic Alkylation of Phosphonates and Phosphine Oxides with Grignard Reagents
2013 StandoutNobel
Crystal Structure of Calf Spleen Purine Nucleoside Phosphorylase with Two Full Trimers in the Asymmetric Unit: Important Implications for the Mechanism of Catalysis
2004 StandoutNobel
The role of autophagy in neurodegenerative disease
2013 Standout
Purine nucleoside phosphorylase: A target for drug design
1993
4‐Trifluoromethyl‐Substituted Coumarins with Large Stokes Shifts: Synthesis, Bioconjugates, and Their Use in Super‐Resolution Fluorescence Microscopy
2013 StandoutNobel
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid β-peptide
2007 Standout
Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits
2010
Alzheimer's disease
2011 Standout
Computational Enzyme Design
2013 StandoutNobel
Aging Hematopoietic Stem Cells Decline in Function and Exhibit Epigenetic Dysregulation
2007
Introduction of Fluorine and Fluorine‐Containing Functional Groups
2013 Standout
The Endosomal-Lysosomal System of Neurons in Alzheimer's Disease Pathogenesis: A Review
2000
A Strategy for Functional Proteomic Analysis of Glycosidase Activity from Cell Lysates
2004 StandoutNobel
Calf spleen purine-nucleoside phosphorylase: crystal structure of the binary complex with a potent multisubstrate analogue inhibitor
2004
Catalytic antibodies: hapten design strategies and screening methods
2004
Tuning energy transfer in switchable donor–acceptor systems
2008 StandoutNobel
Phosphorylated 3‐Heteroarylcoumarins and Their Use in Fluorescence Microscopy and Nanoscopy
2012 StandoutNobel
Crystal structure of the purine nucleoside phosphorylase (PNP) from Cellulomonas sp. and its implication for the mechanism of trimeric PNPs
1999
Tumor targeting in photodynamic therapy. From glycoconjugated photosensitizers to glycodendrimeric one. Concept, design and properties
2012
Structural and sequence-based classification of glycoside hydrolases
1997 Standout
Crystal structure of calf spleen purine nucleoside phosphorylase in a complex with hypoxanthine at 2.15 Å resolution
1997
Binding of phosphate and sulfate anions by purine nucleoside phosphorylase from E. coli: ligand-dependent quenching of enzyme intrinsic fluorescence
1997
The difluoromethylene group as a replacement for the labile oxygen in steroid sulfates: a new approach to steroid sulfatase inhibitors
2003
Chemical Approaches To Perturb, Profile, and Perceive Glycans
2009 StandoutNobel
Endocytic Pathway Abnormalities Precede Amyloid β Deposition in Sporadic Alzheimer’s Disease and Down Syndrome
2000
Modern Synthetic Methods for Fluorine‐Substituted Target Molecules
2004 Standout
Antiamyloidogenic and Neuroprotective Functions of Cathepsin B: Implications for Alzheimer's Disease
2006
Approaches to labeling and identification of active site residues in glycosidases
1995
Combinatorial protein design: strategies for screening protein libraries
1997 StandoutNobel
Down syndrome
2020 Standout
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
2008 Standout
N-Bromoacetyl-glycopyranosylamines as affinity labels for a β-glucosidase and a cellulase
1993
Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
2020 Standout
A strategy for the isolation of catalytic activities from repertoires of enzymes displayed on phage 1 1Edited by J. Karn
1999 StandoutNobel
ROSETTALIGAND: Protein–small molecule docking with full side‐chain flexibility
2006 StandoutNobel
The molecular pathology of Alzheimer's disease
1991 Standout
Autophagy is involved in the ischemic preconditioning
2008
Chemical Selection for Catalysis in Combinatorial Antibody Libraries
1997 Science
Monofluorination of Organic Compounds: 10 Years of Innovation
2015 Standout
Fluorine in medicinal chemistry
2007 Standout
Autophagy, mitochondria and oxidative stress: cross-talk and redox signalling
2011 Standout
Molecular Recognition of Protein−Ligand Complexes: Applications to Drug Design
1997 Standout
Sulfones and sulfoxides in the total synthesis of biologically active natural compounds
2000
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Design and Synthesis of Activity Probes for Glycosidases
2002
Information Decay in Molecular Docking Screens against Holo, Apo, and Modeled Conformations of Enzymes
2003
Synthesis of chiral and bioactive fluoroorganic compounds
1993
Docking and scoring in virtual screening for drug discovery: methods and applications
2004 Standout
Fluorinated Phosphonates: Synthesis and Biomedical Application
2006
Synthesis, Structure−Activity Relationships, and Biological Evaluation of Fatty Alcohol Phosphates as Lysophosphatidic Acid Receptor Ligands, Activators of PPARγ, and Inhibitors of Autotaxin
2005
Chiral recognition and chiral sensing using zinc porphyrin dimers
2002 StandoutNobel
Enantiomeric epoxidation of 4-chlorostyrene with H2O2catalysed by robust chloro manganese(III )meso-5,10,15,20-tetrakis [2-chloro-6-(2,3,4,6-tetraacetyl-O-β-glucosyl)phenyl] porphyrins
1994
Aglycone fragmentation accompanies β-glucosidase catalyzed hydrolysis of salicortin, a naturally-occurring phenol glycoside
1990
A facile and efficient synthesis of diethyl α,α‐chlorofluoroalkanephosphonates
2010
Catalytic Asymmetric Conjugate Addition of Grignard Reagents to α,β-Unsaturated Sulfones
2008 StandoutNobel
o-Quinone methides: intermediates underdeveloped and underutilized in organic synthesis
2002 Standout
Fluorinated Ylides and Related Compounds
1996
Gold Nanoparticles in Chemical and Biological Sensing
2012 Standout
Chemoselective Elaboration of O-Linked Glycopeptide Mimetics by Alkylation of 3-ThioGalNAc
2001 StandoutNobel
The Catalytic Asymmetric Aminohydroxylation of Unsaturated Phosphonates
1999 StandoutNobel
Asymmetric synthesis of hydroxyphosphonates
2005
Diethyl Fluoronitromethylphosphonate: Synthesis and Application in Nucleophilic Fluoroalkyl Additions
2013
Alternative Synthetic Methods through New Developments in Catalysis by Gold
2008 Standout
New photosensitizers for photodynamic therapy
2016 Standout
The autophagy-lysosomal degradation pathway: role in neurodegenerative disease and therapy
2007
(α-Monofluoroalkyl)phosphonates: a class of isoacidic and “tunable” mimics of biological phosphates
2001
Synthesis of the (α,α-difluoroalkyl)phosphonate analogue of phosphoserine
1994
Modifying the β,γ Leaving-Group Bridging Oxygen Alters Nucleotide Incorporation Efficiency, Fidelity, and the Catalytic Mechanism of DNA Polymerase β
2006 StandoutNobel
Aromatic Trifluoromethylation with Metal Complexes
2011 Standout
Reconstitution of Apo-Glucose Dehydrogenase on Pyrroloquinoline Quinone-Functionalized Au Nanoparticles Yields an Electrically Contacted Biocatalyst
2005
Fluorinated organometallics: Perfluoroalkyl and functionalized perfluoroalkyl organometallic reagents in organic synthesis
1992
Glycosyltransferases: Structures, Functions, and Mechanisms
2007 Standout
A facile and general preparation of α,α-difluoro benzylic phosphonates by the CuCl promoted coupling reaction of the (diethylphosphonyl)difluoromethylcadmium reagent with aryl lodides
1996
Synthesis of monofluoro- and difluoro- methylenephosphonate analogues of sn-glycerol-3-phosphate as substrates for glycerol-3-phosphate dehydrogenase and the X-ray structure of the fluoromethylenephosphonate moiety
1996
Coexistence of Quiescent and Active Adult Stem Cells in Mammals
2010 StandoutScience
Design and Synthesis of an Enzyme Activity-Based Labeling Molecule with Fluorescence Spectral Change
2006
Mechanisms of Endocytosis
2009 Standout
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
Methods for the synthesis of gem-difluoromethylene compounds
1996
Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design
2011 Standout
Works of Anne Ehrhard being referenced
A Possible Role for Cathepsins D, E, and B in the Processing of β‐amyloid Precursor Protein in Alzheimer's Disease
1997
1,1-Difluoroalkyl glucosides: a new class of enzyme-activated irreversible inhibitors of .alpha.-glucosidases
1989
Ortho- and para-(difluoromethyl)aryl-β-d-glucosides: A new class of enzyme-activated irreversible inhibitors of β-glucosidases
1990
ChemInform Abstract: 9‐(Difluorophosphonoalkyl)guanines as a New Class of Multisubstrate Analogue Inhibitors of Purine Nucleoside Phosphorylase.
1991
9-(Difluorophosphonoalkyl)guanines as a new class of multisubstrate analog inhibitors of purine nucleoside phosphorylase
1991
Fluorophosphonate derivatives of N9-benzylguanine as potent, slow-binding multisubstrate analogue inhibitors of purine nucleoside phosphorylase
1996
Phosphonate derivatives of N9-benzylguanine: a new class of potent purine nucleoside phosphorylase inhibitors
1992