Standout Papers

Distinct Signaling Events Downstream of mTOR Cooperate To Mediate the Effects of Amino Acids an... 2005 2026 2012 2019 171
  1. Distinct Signaling Events Downstream of mTOR Cooperate To Mediate the Effects of Amino Acids and Insulin on Initiation Factor 4E-Binding Proteins (2005)
    Xuemin Wang, Anne Beugnet et al. Molecular and Cellular Biology

Citation Impact

Citing Papers

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases
2011 Standout
High-Throughput Mapping of a Dynamic Signaling Network in Mammalian Cells
2005 StandoutScience
A Gene Network Regulating Lysosomal Biogenesis and Function
2009 StandoutScience
mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs
2010 Science
mTOR Kinase Inhibition Causes Feedback-Dependent Biphasic Regulation of AKT Signaling
2011
mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H + -ATPase
2011 Science
The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1
2008 StandoutScience
TOR Signaling in Growth and Metabolism
2006 Standout
A Role for Mammalian Target of Rapamycin in Regulating T Cell Activation versus Anergy
2007
A conserved abundant cytoplasmic long noncoding RNA modulates repression by Pumilio proteins in human cells
2016
β-Arrestin-mediated Signaling Regulates Protein Synthesis
2008 StandoutNobel
A dynamic model of proteome changes reveals new roles for transcript alteration in yeast
2011
Rapid Turnover of the mTOR Complex 1 (mTORC1) Repressor REDD1 and Activation of mTORC1 Signaling following Inhibition of Protein Synthesis
2007
Identifying sequence features that drive ribosomal association for lncRNA
2018
Differential Membrane Localization of ERas and Rheb, Two Ras-related Proteins Involved in the Phosphatidylinositol 3-Kinase/mTOR Pathway
2005 StandoutNobel
lincRNAs: Genomics, Evolution, and Mechanisms
2013 Standout
Regulation and function of mTOR signalling in T cell fate decisions
2012
Specificity in Signal Transduction
2004
The Structure and Function of the Eukaryotic Ribosome
2012
mTOR Signaling in Growth Control and Disease
2012 Standout
MYC on the Path to Cancer
2012 Standout
A view on drug resistance in cancer
2019 StandoutNature
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
The Proline-rich Akt Substrate of 40 kDa (PRAS40) Is a Physiological Substrate of Mammalian Target of Rapamycin Complex 1
2007
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
An ATP-competitive Mammalian Target of Rapamycin Inhibitor Reveals Rapamycin-resistant Functions of mTORC1
2009 Standout
High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome
2013 StandoutNatureNobel
N6-methyladenosine Modulates Messenger RNA Translation Efficiency
2015 Standout
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
2004 StandoutNobel
Mechanisms of Long Non-coding RNAs in Mammalian Nervous System Development, Plasticity, Disease, and Evolution
2015
Autophagy fights disease through cellular self-digestion
2008 StandoutNature
Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets
2009 Standout
Functional Classification and Experimental Dissection of Long Noncoding RNAs
2018 Standout
Tuberous Sclerosis Complex Gene Products, Tuberin and Hamartin, Control mTOR Signaling by Acting as a GTPase-Activating Protein Complex toward Rheb
2003 Standout
A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?
2011 Standout
Mechanisms of miRNA-mediated post-transcriptional regulation in animal cells
2009
Evolution to the rescue: using comparative genomics to understand long non-coding RNAs
2016
Temsirolimus, Interferon Alfa, or Both for Advanced Renal-Cell Carcinoma
2007 Standout
Translational control in cancer
2010
Active-Site Inhibitors of mTOR Target Rapamycin-Resistant Outputs of mTORC1 and mTORC2
2009
Transposable Elements Are Major Contributors to the Origin, Diversification, and Regulation of Vertebrate Long Noncoding RNAs
2013
Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation
2013 StandoutNobel
Hypoxia drives glucose transporter 3 expression through hypoxia-inducible transcription factor (HIF)–mediated induction of the long noncoding RNA NICI
2019 StandoutNobel
The RSK factors of activating the Ras/MAPK signaling cascade
2008
The Role of Long Noncoding RNAs in Central Nervous System and Neurodegenerative Diseases
2018
Network organization of the human autophagy system
2010 StandoutNature
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Upstream and downstream of mTOR
2004 Standout
TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival
2003 Standout
miRNA–target chimeras reveal miRNA 3′-end pairing as a major determinant of Argonaute target specificity
2015 StandoutNobel
Viral interactions with macroautophagy: A double-edged sword
2010
Long non-coding RNAs: new players in cell differentiation and development
2013 Standout
Autophagy in the Pathogenesis of Disease
2008 Standout
Rheb Binds and Regulates the mTOR Kinase
2005
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
2009 StandoutNature
On the Dependency of Cellular Protein Levels on mRNA Abundance
2016 Standout
The Tuberous Sclerosis Protein TSC2 Is Not Required for the Regulation of the Mammalian Target of Rapamycin by Amino Acids and Certain Cellular Stresses
2005
Signalling and autophagy regulation in health, aging and disease
2006
Methods in Mammalian Autophagy Research
2010 Standout
Towards a complete map of the human long non-coding RNA transcriptome
2018
Regulation of mammalian translation factors by nutrients
2002
The cancerous translation apparatus
2011
Cytoplasmic long noncoding RNAs are frequently bound to and degraded at ribosomes in human cells
2016
The Vam6 GEF Controls TORC1 by Activating the EGO Complex
2009
A Cytoplasmic NF-κB Interacting Long Noncoding RNA Blocks IκB Phosphorylation and Suppresses Breast Cancer Metastasis
2015
AKT/PKB Signaling: Navigating the Network
2017 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Ser-64 and Ser-111 in PHAS-I Are Dispensable for Insulin-stimulated Dissociation from eIF4E
2003
PRAS40 Is a Target for Mammalian Target of Rapamycin Complex 1 and Is Required for Signaling Downstream of This Complex
2007
Multiallelic Disruption of the rictor Gene in Mice Reveals that mTOR Complex 2 Is Essential for Fetal Growth and Viability
2006
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Global quantification of mammalian gene expression control
2011 StandoutNature
Termination of autophagy and reformation of lysosomes regulated by mTOR
2010 StandoutNature
Transcriptome-wide Identification of RNA-Binding Protein and MicroRNA Target Sites by PAR-CLIP
2010 Standout
Akt/PKB and p38 MAPK signaling, translational initiation and longevity in Snell dwarf mouse livers
2004
Early cellular changes after blockage of chaperone-mediated autophagy
2008
Long Noncoding RNAs: Cellular Address Codes in Development and Disease
2013 Standout
Thr2446 Is a Novel Mammalian Target of Rapamycin (mTOR) Phosphorylation Site Regulated by Nutrient Status
2004
Gene regulation by long non-coding RNAs and its biological functions
2020 Standout
Target of rapamycin (TOR): an integrator of nutrient and growth factor signals and coordinator of cell growth and cell cycle progression
2004 Standout
PRAS40 Regulates mTORC1 Kinase Activity by Functioning as a Direct Inhibitor of Substrate Binding
2007
Signaling from Akt to FRAP/TOR Targets both 4E-BP and S6K in Drosophila melanogaster
2003
A Novel mTOR-Regulated Phosphorylation Site in Elongation Factor 2 Kinase Modulates the Activity of the Kinase and Its Binding to Calmodulin
2004
The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction
2010 StandoutNobel
Insulin‐like growth factor‐1 and TNF‐α regulate autophagy through c‐jun N‐terminal kinase and Akt pathways in human atherosclerotic vascular smooth cells
2006
eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation
2016 StandoutNatureNobel
The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis
2012
mTOR Controls Cell Cycle Progression through Its Cell Growth Effectors S6K1 and 4E-BP1/Eukaryotic Translation Initiation Factor 4E
2003
Target of Rapamycin (TOR) in Nutrient Signaling and Growth Control
2011
Regulation of Immune Responses by mTOR
2012
The mTOR Pathway in the Control of Protein Synthesis
2006
Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9
2015
Regulation and function of the RSK family of protein kinases
2011
mTOR Inhibition by Rapamycin Prevents β-Cell Adaptation to Hyperglycemia and Exacerbates the Metabolic State in Type 2 Diabetes
2008
Two Motifs in the Translational Repressor PHAS-I Required for Efficient Phosphorylation by Mammalian Target of Rapamycin and for Recognition by Raptor
2003
Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3)
2011 StandoutNobel
TOR Signaling
2003
Signalling to translation: how signal transduction pathways control the protein synthetic machinery
2007
mTOR Pathway as a Target in Tissue Hypertrophy
2006
Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice
2008 StandoutNobel
Regulation of mRNA Translation and Stability by microRNAs
2010 Standout
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel

Works of Anne Beugnet being referenced

Target of Rapamycin (TOR)-signaling and RAIP Motifs Play Distinct Roles in the Mammalian TOR-dependent Phosphorylation of Initiation Factor 4E-binding Protein 1
2003
Eukaryotic initiation factor 6 is rate-limiting in translation, growth and transformation
2008 Nature
Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeat
2012 Nature
Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability
2003
Evidence that the dephosphorylation of Ser535 in the ∊-subunit of eukaryotic initiation factor (eIF) 2B is insufficient for the activation of eIF2B by insulin
2002
Eukaryotic initiation factor 6 mediates a continuum between 60S ribosome biogenesis and translation
2009
The C Terminus of Initiation Factor 4E-Binding Protein 1 Contains Multiple Regulatory Features That Influence Its Function and Phosphorylation
2003
Distinct Signaling Events Downstream of mTOR Cooperate To Mediate the Effects of Amino Acids and Insulin on Initiation Factor 4E-Binding Proteins
2005 StandoutNobel
Rankless by CCL
2026