Standout Papers
Citation Impact
Citing Papers
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
Comparative linkage analysis and visualization of high-density oligonucleotide SNP array data
2005
Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter
1996 StandoutNature
Psoriasis
2009 Standout
The antimicrobial peptide LL37 is a T-cell autoantigen in psoriasis
2014
Pathogenesis and clinical features of psoriasis
2007 Standout
Thymus, innate immunity and autoimmune arthritis: Interplay of gene and environment
2011 StandoutNobel
EULAR evidence-based recommendations for cardiovascular risk management in patients with rheumatoid arthritis and other forms of inflammatory arthritis
2009 Standout
Polymorphisms of the IL12B and IL23R Genes Are Associated with Psoriasis
2008
Pathogenesis and therapy of psoriasis
2007 StandoutNature
Impact of T-cell costimulation modulation in patients with undifferentiated inflammatory arthritis or very early rheumatoid arthritis: a clinical and imaging study of abatacept (the ADJUST trial)
2009
A Candidate Gene Approach Identifies the TRAF1/C5 Region as a Risk Factor for Rheumatoid Arthritis
2007
Juvenile idiopathic arthritis
2007 Standout
Foxp3 controls regulatory T-cell function by interacting with AML1/Runx1
2007 StandoutNatureNobel
Etiology of Type 1 Diabetes
2010
Polymorphisms in the CTLA-4 Gene and Rheumatoid Arthritis Susceptibility: A Meta-analysis
2012
Evidence for susceptibility determinant(s) to psoriasis vulgaris in or near PTPN22 in German patients
2005
Activation of facilitation calcium channels in chromaffin cells by D1 dopamine receptors through a cAMP/protein kinase A-dependent mechanism
1990 Nature
Psoriasis
2021 Standout
The role of lactogenic hormones in maternal behavior in female rats
1994
Prolactin message in brain and pituitary of adult male rats is identical: PCR cloning and sequencing of hypothalamic prolactin cDNA from intact and hypophysectomized adult male rats.
1992
The Pathogenesis of Rheumatoid Arthritis
2011 Standout
Prolactin (PRL) Receptors Are Colocalized in Dopaminergic Neurons in Fetal Hypothalamic Cell Cultures: Effect of PRL on Tyrosine Hydroxylase Activity1
1997
PLINK: A Tool Set for Whole-Genome Association and Population-Based Linkage Analyses
2007 Standout
Differentiation of Y79 cells induced by prolonged exposure to insulin
1997
Phosphorylation and Desensitization of the Human β1-Adrenergic Receptor
1995 StandoutNobel
An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis
2003
Psoriasis
2015 Standout
Defining the core Arabidopsis thaliana root microbiome
2012 StandoutNature
Interleukin-17 and Type 17 Helper T Cells
2009 Standout
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function
2006 StandoutNature
Systematic review of the comorbidity of irritable bowel syndrome with other disorders: What are the causes and implications?
2002 Standout
Dopamine D1 receptor mutant mice are deficient in striatal expression of dynorphin and in dopamine-mediated behavioral responses
1994 Nobel
Phosphorylation of the Type 1A Angiotensin II Receptor by G Protein-coupled Receptor Kinases and Protein Kinase C
1996 StandoutNobel
The pathogenesis of psoriatic arthritis
2018
Desensitization of human renal D1 dopamine receptors by G protein-coupled receptor kinase 4
2002
Electrophysiological Correlates of Psychomotor Stimulant‐induced Sensitizationa
1992
Recent progress in rheumatoid arthritis genetics: one step towards improved patient care
2009
Desensitization of the human D1 dopamine receptor: Evidence for Involvement of both cyclic AMP-dependent and receptor-specific protein kinases
1991
Role of TNF–TNF Receptor 2 Signal in Regulatory T Cells and Its Therapeutic Implications
2018
Genetic epidemiology of diabetes
2005
Four Consecutive Serines in the Third Intracellular Loop Are the Sites for β-Adrenergic Receptor Kinase-mediated Phosphorylation and Desensitization of the α2A-Adrenergic Receptor
1995
Low-Level Lead Exposure Selectively Enhances Dopamine Overflow in Nucleus Accumbens: AnIn VivoElectrochemistry Time Course Assessment
1998
Molecular mechanisms of membrane receptor desensitization
1993
Polymorphisms in the PTPN22 region are associated with psoriasis of early onset
2008
Guidelines for Genotyping in Genomewide Linkage Studies: Single-Nucleotide–Polymorphism Maps Versus Microsatellite Maps
2004
An Akt/β-Arrestin 2/PP2A Signaling Complex Mediates Dopaminergic Neurotransmission and Behavior
2005 StandoutNobel
Phosphorylation and Desensitization of Human Endothelin A and B Receptors
1997 StandoutNobel
BODIPY–Thiophene Copolymers as p‐Channel Semiconductors for Organic Thin‐Film Transistors
2013 StandoutNobel
The −319C/+49G/CT60G Haplotype of CTLA-4 Gene Confers Susceptibility to Rheumatoid Arthritis in Mexican Population
2013
Functional mapping and annotation of genetic associations with FUMA
2017 Standout
Neo‐ligands for innate immune receptors and the etiology of sterile inflammatory disease
2007 StandoutNobel
Rheumatoid arthritis
2010 Standout
Identification of the G Protein-coupled Receptor Kinase Phosphorylation Sites in the Human β2-Adrenergic Receptor
1996 StandoutNobel
Cytotoxic T lymphocyte associated antigen-4 (CTLA-4) +49 A>G gene polymorphism in Egyptian cases with rheumatoid arthritis
2014
Role of PTPN22 in type 1 diabetes and other autoimmune diseases
2006
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Evidence for treating rheumatoid arthritis to target: results of a systematic literature search
2010
Prolactin activates all three populations of hypothalamic neuroendocrine dopaminergic neurons in ovariectomized rats
1999
Prolactin Receptor Gene Expression in Specific Hypothalamic Nuclei Increases With Age
1996
Molecular Dissection of Psoriasis: Integrating Genetics and Biology
2009
The distribution of lactogen receptors in the mammalian hypothalamus: an in vitro autoradiographic analysis of the rabbit and rat
1990
The Chemistry of Fluorescent Bodipy Dyes: Versatility Unsurpassed
2007 Standout
Comparison of Ustekinumab and Etanercept for Moderate-to-Severe Psoriasis
2010
Genome-wide association studies for common diseases and complex traits
2005 Standout
Further Genetic Evidence for Three Psoriasis-Risk Genes: ADAM33, CDKAL1, and PTPN22
2008
Prolactin Receptor mRNA Localization in the Hypothalamus by in situ Hybridization
1994
Cancer-related inflammation
2008 StandoutNature
Ovarian steroids differentially regulate the expression of PRL-R in neuroendocrine dopaminergic neuron populations: a double label confocal microscopic study
1998
Association of the CTLA-4 +49A/G polymorphism with rheumatoid arthritis in Chinese Han population
2012
Genetic predisposition to autoimmunity – What have we learned?
2011
Effects of prolactin on expression of the mRNAs encoding the immediate early genes zif/268 (NGF1-A), nur/77 (NGF1-B), c-fos and c-jun in the hypothalamus
1998
Genetics of autoimmune diseases in humans and in animal models
2002
The human skin microbiome
2018 Standout
Differential Regulation of Dopamine D1A Receptor Responsiveness by Various G Protein-coupled Receptor Kinases
1996 StandoutNobel
Establishment of NOD-Pdcd1-/-mice as an efficient animal model of type I diabetes
2005 StandoutNobel
The kinase Grk2 regulates Nedd4/Nedd4-2-dependent control of epithelial Na + channels
2004 StandoutNobel
Psoriasis and Genetics
2020
Ovarian cancer cell–derived migration inhibitory factor enhances tumor growth, progression, and angiogenesis
2007 Standout
Drug Efficacy at G Protein–Coupled Receptors
2002
B7x in the Periphery Abrogates Pancreas-Specific Damage Mediated by Self-reactive CD8 T Cells
2012 StandoutNobel
Nongastrointestinal Disorders in the Irritable Bowel Syndrome
2000
IL-17 and Th17 Cells
2009 Standout
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Heterozygous α 2A -adrenergic receptor mice unveil unique therapeutic benefits of partial agonists
2002 StandoutNobel
Molecular cloning and expression of a D1 dopamine receptor linked to adenylyl cyclase activation.
1990
Central prolactin infusions stimulate maternal behavior in steroid-treated, nulliparous female rats.
1990
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
2016 StandoutNobel
Monoclonal antibodies reveal receptor specificity among G-protein-coupled receptor kinases.
1996 StandoutNobel
Trapping of a Spatial Transient State During the Framework Transformation of a Porous Coordination Polymer
2014 StandoutNobel
Different G protein-coupled receptor kinases govern G protein and β-arrestin-mediated signaling of V2 vasopressin receptor
2005 StandoutNobel
Drug Abuse: Hedonic Homeostatic Dysregulation
1997 StandoutScience
Prolactin: Structure, Function, and Regulation of Secretion
2000 Standout
Altered striatal function in a mutant mouse lacking D1A dopamine receptors.
1994
Detection of T cell responses to a ubiquitous cellular protein in autoimmune disease
2014 StandoutScienceNobel
The rat prolactin gene is expressed in brain tissue: detection of normal and alternatively spliced prolactin messenger RNA.
1992
D 1 and D 2 Dopamine Receptor-regulated Gene Expression of Striatonigral and Striatopallidal Neurons
1990 StandoutScience
Mortality in rheumatoid arthritis: 2008 update.
2009
T cell costimulation and coinhibition: genetics and disease.
2011
Chemical Chaperones Reduce ER Stress and Restore Glucose Homeostasis in a Mouse Model of Type 2 Diabetes
2006 StandoutScience
Immunity to Citrullinated Proteins in Rheumatoid Arthritis
2008
THE GENETICS OF PSORIASIS AND AUTOIMMUNITY
2005
In vivo labeling of L-type Ca2+ channels by fluorescent dihydropyridines: evidence for a functional, extracellular heparin-binding site.
1992
Pathophysiology, Clinical Presentation, and Treatment of Psoriasis
2020 Standout
Dopamine Receptors: From Structure to Function
1998 Standout
Role of Brain Insulin Receptor in Control of Body Weight and Reproduction
2000 StandoutScience
Unravelling the effects of the environment and host genotype on the gut microbiome
2011
Works of Anne Barton being referenced
Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis
2010
Optimisation of methods for bacterial skin microbiome investigation: primer selection and comparison of the 454 versus MiSeq platform
2017
Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13
2008
Association between the PTPN22 gene and rheumatoid arthritis and juvenile idiopathic arthritis in a UK population: Further support that PTPN22 is an autoimmunity gene
2005
Investigation of rheumatoid arthritis susceptibility genes identifies association of AFF3 and CD226 variants with response to anti-tumour necrosis factor treatment
2010
Association between rheumatoid arthritis and polymorphism of tumor necrosis factor receptor II, but not tumor necrosis factor receptor I, in Caucasians
2001
Haplotype analysis in simplex families and novel analytic approaches in a case–control cohort reveal no evidence of association of the CTLA‐4 gene with rheumatoid arthritis
2004
Autoradiographic Identification of Prolactin Binding Sites in Rat Median Eminence
1989
Characterization of Novel Fluorescent Ligands with High Affinity for D1 and D2 Dopaminergic Receptors
1989
Reevaluation of the interaction between HLA–DRB1 shared epitope alleles, PTPN22, and smoking in determining susceptibility to autoantibody‐positive and autoantibody‐negative rheumatoid arthritis in a large UK Caucasian population
2009
The role of DMARDs in reducing the immunogenicity of TNF inhibitors in chronic inflammatory diseases
2013
Capture Hi-C reveals novel candidate genes and complex long-range interactions with related autoimmune risk loci
2015
Association of CD40 with rheumatoid arthritis confirmed in a large UK case-control study
2009
Whole‐genome linkage analysis of rheumatoid arthritis susceptibility loci in 252 affected sibling pairs in the United Kingdom
2002
Investigation of susceptibility loci identified in the UK rheumatoid arthritis whole‐genome scan in a further series of 217 UK affected sibling pairs
2004
Expression of Functional D2 Dopamine Receptors Following Differentiation of Y‐79 Human Retinoblastoma Cells
1990
Genetic susceptibility to rheumatoid arthritis: An emerging picture
2009
Association of the HLA–DRB1 gene with premature death, particularly from cardiovascular disease, in patients with rheumatoid arthritis and inflammatory polyarthritis
2008
Evidence to support IL-13 as a risk locus for psoriatic arthritis but not psoriasis vulgaris
2011
Overlap of disease susceptibility loci for rheumatoid arthritis and juvenile idiopathic arthritis
2009
Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23
2016
Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility
2008
Investigation of association of the IL12B and IL23R genes with psoriatic arthritis
2008
A functional haplotype of the PADI4 gene associated with rheumatoid arthritis in a Japanese population is not associated in a United Kingdom population
2004
Association between anti-tumour necrosis factor treatment response and genetic variants within the TLR and NFκB signalling pathways
2010
A single nucleotide polymorphism in exon 1 of cytotoxic T-lymphocyte-associated-4 (CTLA-4) is not associated with rheumatoid arthritis
2000
Multiple fluorescent ligands for dopamine receptors. I. Pharmacological characterization and receptor selectivity
1991
Identification of a novel susceptibility locus for juvenile idiopathic arthritis by genome‐wide association analysis
2008
Increased Prevalence of Sicca Complex and Fibromyalgia in Patients With Irritable Bowel Syndrome
1999
Genetic susceptibility to psoriasis and psoriatic arthritis: implications for therapy
2011
Investigating the role of the HLA-Cw*06 and HLA-DRB1 genes in susceptibility to psoriatic arthritis: comparison with psoriasis and undifferentiated inflammatory arthritis
2007
Whole-Genome Scan, in a Complex Disease, Using 11,245 Single-Nucleotide Polymorphisms: Comparison with Microsatellites
2004
Genotypic variability-based genome-wide association study identifies non-additive loci HLA-C and IL12B for psoriasis
2017
High resolution linkage and association mapping identifies a novel rheumatoid arthritis susceptibility locus homologous to one linked to two rat models of inflammatory arthritis
2001
Macrophage migration inhibitory factor (MIF) gene polymorphism is associated with susceptibility to but not severity of inflammatory polyarthritis
2003
A Genome-Wide Association Study of Psoriasis and Psoriatic Arthritis Identifies New Disease Loci
2008
Agonist-induced desensitization of D1-dopamine receptors linked to adenylyl cyclase activity in cultured NS20Y neuroblastoma cells.
1990
Differential action of bromocriptine on nigrostriatal versus mesolimbic dopaminergic neurons
1987
Direct visualization and cellular localization of D1 and D2 dopamine receptors in rat forebrain by use of fluorescent ligands.
1989
Agonist-induced desensitization of D2 dopamine receptors in human Y-79 retinoblastoma cells.
1991
Evidence for common genetic control in pathways of inflammation for Crohn's disease and psoriatic arthritis
2005