Anne B. Need

A BOILED‐Egg To Predict Gastrointestinal Absorption and Brain Penetration of Small Molecules

A Meta-Analysis of Cytokines in Major Depression

Glutamate-based antidepressants: 20 years on

Glutamate Receptor Ion Channels: Structure, Regulation, and Function

Dysfunction of the prefrontal cortex in addiction: neuroimaging findings and clinical implications

Discovery of heterobicyclic templates for novel metabotropic glutamate receptor subtype 5 antagonists

Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework

A therapeutic role for cannabinoid CB1 receptor antagonists in major depressive disorders

Review of Pharmacological Treatment in Mood Disorders and Future Directions for Drug Development

Trends in GPCR drug discovery: new agents, targets and indications

HPLC and TLC methods for analysis of [ 18 F]FDG and its metabolites from biological samples

Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders

Neurobiology of depression: an integrated view of key findings

The Endocannabinoid System as an Emerging Target of Pharmacotherapy

The pharmacology of the endocannabinoid system: functional and structural interactions with other neurotransmitter systems and their repercussions in behavioral addiction

Development of allosteric modulators of GPCRs for treatment of CNS disorders

Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial

Artificial intelligence in drug discovery and development

Palladium-Catalyzed Suzuki−Miyaura Cross-Coupling Reactions Employing Dialkylbiaryl Phosphine Ligands

Target identification among known drugs by deep learning from heterogeneous networks

CNS Drug Design: Balancing Physicochemical Properties for Optimal Brain Exposure

Applications of Fluorine in Medicinal Chemistry

A Philosophy for CNS Radiotracer Design

Metabotropic Glutamate 5 Receptor Antagonism Is Associated with Antidepressant-Like Effects in Mice

Analgesic effects of serotonergic, noradrenergic or dual reuptake inhibitors in the carrageenan test in rats: Evidence for synergism between serotonergic and noradrenergic reuptake inhibition

Glucose Metabolic Trapping in Mouse Arteries: Nonradioactive Assay of Atherosclerotic Plaque Inflammation Applicable to Drug Discovery

Use of LC/MS to assess brain tracer distribution in preclinical, in vivo receptor occupancy studies: Dopamine D2, serotonin 2A and NK-1 receptors as examples

The relationship of in vivo central CB1 receptor occupancy to changes in cortical monoamine release and feeding elicited by CB1 receptor antagonists in rats

In vivo rat brain opioid receptor binding of LY255582 assessed with a novel method using LC/MS/MS and the administration of three tracers simultaneously

Identifying Novel Radiotracers for PET Imaging of the Brain: Application of LC-MS/MS to Tracer Identification

In Vivo Receptor Occupancy in Rodents by LC-MS/MS