Citation Impact
Citing Papers
Aquaporin-3 mediates hydrogen peroxide uptake to regulate downstream intracellular signaling
2010
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
A role for DNA-mediated charge transport in regulating p53: Oxidation of the DNA-bound protein from a distance
2007
High burden and pervasive positive selection of somatic mutations in normal human skin
2015 StandoutScience
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Loss of cryptochrome reduces cancer risk in p53 mutant mice
2009 StandoutNobel
Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma
2010 StandoutScience
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
2010 StandoutNobel
The regulation of cellular metabolism by tumor suppressor p53
2013
Tp53-induced Glycolysis and Apoptosis Regulator (TIGAR) Protects Glioma Cells from Starvation-induced Cell Death by Up-regulating Respiration and Improving Cellular Redox Homeostasis
2012
ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome
2006
Cancer Cell Metabolism
2011
The DNA-damage response in human biology and disease
2009 StandoutNature
Regulation of AIF expression by p53
2006
The role of nuclear lamin B1 in cell proliferation and senescence
2011
Telomerase Reverse Transcriptase Delays Aging in Cancer-Resistant Mice
2008
Stromal fibroblasts in cancer initiation and progression
2004 StandoutNature
mTOR Signaling in Growth Control and Disease
2012 Standout
A view on drug resistance in cancer
2019 StandoutNature
Ferroptosis as a p53-mediated activity during tumour suppression
2015 StandoutNature
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
p53 Regulates Hematopoietic Stem Cell Quiescence
2009
Protein phosphatase 2A regulatory subunits and cancer
2008
TIGAR, a p53-Inducible Regulator of Glycolysis and Apoptosis
2006 Standout
p53 polymorphisms: cancer implications
2009
p53 and metabolism
2009
Exploiting Thiol Modifications
2004
HIF-Dependent Antitumorigenic Effect of Antioxidants In Vivo
2007 StandoutNobel
The genetics of ageing
2010 StandoutNature
A microRNA component of the p53 tumour suppressor network
2007 StandoutNature
AMP‐activated protein kinase and cancer
2009
p53: new roles in metabolism
2007
A role for mitochondria in NLRP3 inflammasome activation
2010 StandoutNature
Increased Oxidative Metabolism in the Li–Fraumeni Syndrome
2013
Cellular Senescence in Cancer and Aging
2007 Standout
The multifaceted roles of fatty acid synthesis in cancer
2016
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
2011 StandoutNature
TIGAR Is Required for Efficient Intestinal Regeneration and Tumorigenesis
2013
Axis of ageing: telomeres, p53 and mitochondria
2012
ROS and p53: A versatile partnership
2008
ROS Function in Redox Signaling and Oxidative Stress
2014 Standout
New plays in the p53 theater
2010
Hydrogen Peroxide Sensing and Signaling
2007
Rational design of α-helical tandem repeat proteins with closed architectures
2015 StandoutNatureNobel
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Genetically programmed chiral organoborane synthesis
2017 StandoutNatureNobel
Blinded by the Light: The Growing Complexity of p53
2009 Standout
The dark side of a tumor suppressor: anti-apoptotic p53
2008
Role of Oxidative Modifications in Atherosclerosis
2004 Standout
Regulation of cancer cell metabolism
2011 Standout
ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis
2007 Standout
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition
2010
The P53 pathway: what questions remain to be explored?
2006
PRIMA-1 Reactivates Mutant p53 by Covalent Binding to the Core Domain
2009
Anti‐aging activity of the Ink4/Arf locus
2009
The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing
2010
p53 in health and disease
2007 Standout
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Akt Determines Replicative Senescence and Oxidative or Oncogenic Premature Senescence and Sensitizes Cells to Oxidative Apoptosis
2008
The Sestrins Interact with GATOR2 to Negatively Regulate the Amino-Acid-Sensing Pathway Upstream of mTORC1
2014
Modulation of intracellular ROS levels by TIGAR controls autophagy
2009
Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
2020 StandoutNobel
Quantitative reactivity profiling predicts functional cysteines in proteomes
2010 StandoutNatureNobel
Delayed ageing through damage protection by the Arf/p53 pathway
2007 Nature
The role of senescent cells in ageing
2014 StandoutNature
Monoacylglycerol Lipase Regulates a Fatty Acid Network that Promotes Cancer Pathogenesis
2009
The CASTOR Proteins Are Arginine Sensors for the mTORC1 Pathway
2016
Ligand binding by repeat proteins: natural and designed
2008
The Hallmarks of Aging
2013 Standout
Sestrins Function as Guanine Nucleotide Dissociation Inhibitors for Rag GTPases to Control mTORC1 Signaling
2014
Acetylation of the p53 DNA-Binding Domain Regulates Apoptosis Induction
2006
Growth-Inhibitory and Tumor- Suppressive Functions of p53 Depend on Its Repression of CD44 Expression
2008
p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling
2008
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Disruption of the circadian clock due to theClockmutation has discrete effects on aging and carcinogenesis
2008
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
2009 Standout
Autophagy in immunity and inflammation
2011 StandoutNature
p53 and disease: when the guardian angel fails
2006
The first 30 years of p53: growing ever more complex
2009 Standout
Oxidation of a Eukaryotic 2-Cys Peroxiredoxin Is a Molecular Switch Controlling the Transcriptional Response to Increasing Levels of Hydrogen Peroxide
2005
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
2009 StandoutNature
Serine/Threonine Phosphatases: Mechanism through Structure
2009
Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function
2010
Proliferation of aneuploid human cells is limited by a p53-dependent mechanism
2010
Clues from cell metabolism
2010 StandoutNatureNobel
Proteomic detection of hydrogen peroxide-sensitive thiol proteins in Jurkat cells
2005
A Selective, Cell-Permeable Optical Probe for Hydrogen Peroxide in Living Cells
2004
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
A complex thiolate switch regulates the Bacillus subtilis organic peroxide sensor OhrR
2007
Luminescent Chemodosimeters for Bioimaging
2012 Standout
Allele-specific copy number analysis of tumors
2010
Aggregation-Induced Emission: Together We Shine, United We Soar!
2015 Standout
Human TKTL1 implies greater neurogenesis in frontal neocortex of modern humans than Neanderthals
2022 StandoutScienceNobel
Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species
2010
Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases
2014 Standout
Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors
2004
Metabolic reprogramming and cancer progression
2020 StandoutScience
Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway
2015 Science
Antioxidants Accelerate Lung Cancer Progression in Mice
2014
Concurrent and independent genetic alterations in the stromal and epithelial cells of mammary carcinoma: implications for tumorigenesis.
2000
The Two Faces of Reactive Oxygen Species in Cancer
2016
Promotion of direct reprogramming by transformation-deficient Myc
2010 StandoutNobel
The Exocyst at a Glance
2015
A cysteine-sulfinic acid in peroxiredoxin regulates H 2 O 2 -sensing by the antioxidant Pap1 pathway
2005
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Sestrins Inhibit mTORC1 Kinase Activation through the GATOR Complex
2014
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
2017 StandoutNobel
The Arf/p53 Pathway in Cancer and Aging
2008
Works of Anna Sablina being referenced
PME-1 Protects Extracellular Signal-Regulated Kinase Pathway Activity from Protein Phosphatase 2A–Mediated Inactivation in Human Malignant Glioma
2009
Structural Basis of PP2A Inhibition by Small t Antigen
2007
p53-dependent effects of RAS oncogene on chromosome stability and cell cycle checkpoints
1999
The antioxidant function of the p53 tumor suppressor
2005
The Tumor Suppressor PP2A Aβ Regulates the RalA GTPase
2007
The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response
2013
Loss of Chromosome 8p Governs Tumor Progression and Drug Response by Altering Lipid Metabolism
2016
Activation of p53-mediated cell cycle checkpoint in response to micronuclei formation
1998
Regeneration of Peroxiredoxins by p53-Regulated Sestrins, Homologs of Bacterial AhpD
2004 Science