Citation Impact
Citing Papers
Detecting Causality in Complex Ecosystems
2012 StandoutScience
Phase II Trial of Dasatinib in Patients with Metastatic Breast Cancer Using Real-Time Pharmacodynamic Tissue Biomarkers of Src Inhibition to Escalate Dosing
2011
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
2017 Standout
Ganetespib, a Unique Triazolone-Containing Hsp90 Inhibitor, Exhibits Potent Antitumor Activity and a Superior Safety Profile for Cancer Therapy
2011
( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
2013 StandoutScienceNobel
Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress
2011
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Roles of tau protein in health and disease
2017
Pharmacologic Targeting of Hypoxia-Inducible Factors
2019 StandoutNobel
Plasma Hsp90 levels in patients with systemic sclerosis and relation to lung and skin involvement: a cross-sectional and longitudinal study
2021 Standout
Transcriptional data: a new gateway to drug repositioning?
2012
Targeted inhibition of Hsp90 by ganetespib is effective across a broad spectrum of breast cancer subtypes
2013
Neural regulation of hypoxia-inducible factors and redox state drives the pathogenesis of hypertension in a rodent model of sleep apnea
2015 StandoutNobel
Therapeutic strategies for tau mediated neurodegeneration
2012
Endogenous human microRNAs that suppress breast cancer metastasis
2008 StandoutNature
Large-scale chemical dissection of mitochondrial function
2008
The re-emergence of natural products for drug discovery in the genomics era
2015 Standout
Mechanisms, regulation and functions of the unfolded protein response
2020 Standout
Src kinase contributes to the metastatic spread of carcinoma cells
2002
Gene Sets Identified with Oncogene Cooperativity Analysis Regulate In Vivo Growth and Survival of Leukemia Stem Cells
2012
Phosphorylation of ETS1 by Src Family Kinases Prevents Its Recognition by the COP1 Tumor Suppressor
2014 StandoutNobel
Targeting Aβ and tau in Alzheimer's disease, an early interim report
2009
Inhibition of Anthrax Lethal Toxin-Induced Cytolysis of RAW264.7 Cells by Celastrol
2008
Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer
2016
The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics
2011 Standout
Heat shock protein 90: its inhibition and function
2017
Cell cycle proteins as promising targets in cancer therapy
2017 Standout
Autophagic degradation of tau in primary neurons and its enhancement by trehalose
2011
Molecular Understanding and Modern Application of Traditional Medicines: Triumphs and Trials
2007 Standout
The role of autophagy in neurodegenerative disease
2013 Standout
IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling
2019
Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology
2013 Standout
Targeting Ferroptosis to Iron Out Cancer
2019 Standout
Focal adhesion kinase: in command and control of cell motility
2005 Standout
Modulation of oxidative stress as an anticancer strategy
2013 Standout
Inhibition of Simian Virus 40 replication by targeting the molecular chaperone function and ATPase activity of T antigen
2009
Treatment of Obesity with Celastrol
2015 Standout
Cell-Based Assays for High-Throughput Screening
2010
Regulation of stress signaling pathways by nitro-fatty acids
2018
Tau fragmentation, aggregation and clearance: the dual role of lysosomal processing
2009
Mining gene expression profiles: expression signatures as cancer phenotypes
2007
Network medicine: a network-based approach to human disease
2010 Standout
Hsp90-Tau Complex Reveals Molecular Basis for Specificity in Chaperone Action
2014
Small-molecule proteostasis regulators for protein conformational diseases
2011
Tau in physiology and pathology
2015 Standout
ROS Function in Redox Signaling and Oxidative Stress
2014 Standout
Molecular mechanisms of cisplatin resistance
2011 Standout
Targeting the phosphoinositide 3-kinase pathway in cancer
2009 Standout
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
The hypoxic tumor microenvironment: A driving force for breast cancer progression
2015 StandoutNobel
Target identification and mechanism of action in chemical biology and drug discovery
2013
Epithelial–mesenchymal transitions in tumour progression
2002 Standout
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Drug repurposing: progress, challenges and recommendations
2018 Standout
Annual report to the nation on the status of cancer, 1975‐2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates
2009 Standout
How were new medicines discovered?
2011 Standout
Matching chelators to radiometals for radiopharmaceuticals
2013 Standout
Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice
2017
Novobiocin and Additional Inhibitors of the Hsp90 C-Terminal Nucleotide- binding Pocket
2008
Measuring the Pharmacodynamic Effects of a Novel Hsp90 Inhibitor on HER2/neu Expression in Mice Using 89Zr-DFO-Trastuzumab
2010
Ferroptosis: process and function
2016 Standout
Pyrimidinone-peptoid hybrid molecules with distinct effects on molecular chaperone function and cell proliferation
2008
Ganetespib blocks HIF-1 activity and inhibits tumor growth, vascularization, stem cell maintenance, invasion, and metastasis in orthotopic mouse models of triple-negative breast cancer
2013 StandoutNobel
Targeting the androgen receptor pathway in prostate cancer
2008
A network view of disease and compound screening
2009
Adaptive responses to alloxan‐induced mild oxidative stress ameliorate certain tauopathy phenotypes
2011
Translating insights from the cancer genome into clinical practice
2008 Nature
Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases
2019 Standout
The Hallmarks of Aging
2013 Standout
v-Src Rescues Actin-based Cytoskeletal Architecture and Cell Motility and Induces Enhanced Anchorage Independence during Oncogenic Transformation of Focal Adhesion Kinase-null Fibroblasts
2003
Drugging the Cancer Chaperone HSP90
2007
Development and application of Hsp90 inhibitors
2007
Targeting Hsp90 and its co-chaperones to treat Alzheimer’s disease
2014
Tau pathology and neurodegeneration
2013
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals
2015 Standout
Vinculin modulation of paxillin–FAK interactions regulates ERK to control survival and motility
2004
Degradation of tau protein by autophagy and proteasomal pathways
2012
DAMP-sensing receptors in sterile inflammation and inflammatory diseases
2019 Standout
Small Molecule Modulators of Protein–Protein Interactions: Selected Case Studies
2014
The Inflammasomes: Guardians of the Body
2009 Standout
Identification of Targets of the HIF-1 Inhibitor IDF-11774 Using Alkyne-Conjugated Photoaffinity Probes
2016
HSP90 and its inhibitors (Review)
2010
Diversity Oriented Clicking (DOC): Divergent Synthesis of SuFExable Pharmacophores from 2‐Substituted‐Alkynyl‐1‐Sulfonyl Fluoride (SASF) Hubs
2020 StandoutNobel
Impact of Natural Products on Developing New Anti-Cancer Agents
2009 Standout
Transcript Profiling and RNA Interference as Tools To Identify Small Molecule Mechanisms and Therapeutic Potential
2010
Natural Products as Sources of New Drugs from 1981 to 2014
2016 Standout
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets
2020 Standout
Next generation diversity-oriented synthesis: a paradigm shift from chemical diversity to biological diversity
2018
Enabling personalized cancer medicine through analysis of gene-expression patterns
2008 Nature
Works of Anna Rodina being referenced
Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer models
2009
High-Throughput Screening Fluorescence Polarization Assay for Tumor-Specific Hsp90
2007
Selective compounds define Hsp90 as a major inhibitor of apoptosis in small-cell lung cancer
2007
Identification of an Allosteric Pocket on Human Hsp70 Reveals a Mode of Inhibition of This Therapeutically Important Protein
2013
Design, synthesis, and evaluation of small molecule Hsp90 probes
2011
Heat shock protein 90 in neurodegenerative diseases
2010
Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulators
2006
Emerging Hsp90 Inhibitors: From Discovery to Clinic
2006
Phosphorylation of p125FAK and paxillin focal adhesion proteins in src‐transformed cells with different metastatic capacity
1999
Roles of heat-shock protein 90 in maintaining and facilitating the neurodegenerative phenotype in tauopathies
2007