Citation Impact
Citing Papers
A Role for the Protease Falcipain 1 in Host Cell Invasion by the Human Malaria Parasite
2002 Science
Fungal Small RNAs Suppress Plant Immunity by Hijacking Host RNA Interference Pathways
2013 StandoutScience
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
The role of dynamic conformational ensembles in biomolecular recognition
2009 Standout
Co‐ordinated programme of gene expression during asexual intraerythrocytic development of the human malaria parasite Plasmodium falciparum revealed by microarray analysis
2001
Extended disordered proteins: targeting function with less scaffold
2003
Absolute binding free energy calculations: On the accuracy of computational scoring of protein–ligand interactions
2010 StandoutNobel
An Antiviral Mechanism of Nitric Oxide
1999
Evaluation of FKBP and DHFR based destabilizing domains in Saccharomyces cerevisiae
2011
Aspartic proteases of Plasmodium falciparum and other parasitic protozoa as drug targets
2001
Replacement of Isobutyl by Trifluoromethyl in Pepstatin A Selectively Affects Inhibition of Aspartic Proteinases
2005
Intrinsically unstructured proteins and their functions
2005 Standout
Open Babel: An open chemical toolbox
2011 Standout
Verapamil Reversal of Chloroquine Resistance in the Malaria Parasite Plasmodium falciparum Is Specific for Resistant Parasites and Independent of the Weak Base Effect
1995
The MEME Suite
2015 Standout
A General Chemical Method to Regulate Protein Stability in the Mammalian Central Nervous System
2010
Marine natural products
1990 Standout
Ligand-switchable Substrates for a Ubiquitin-Proteasome System
2011
Gene delivery with synthetic (non viral) carriers
2001
Oomycetes, effectors, and all that jazz
2012
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
A Multi-enzyme Cascade of Hemoglobin Proteolysis in the Intestine of Blood-feeding Hookworms
2004
Structurally Mapping Endogenous Heme in the CcmCDE Membrane Complex for Cytochrome c Biogenesis
2018 StandoutNobel
The Transcriptome of the Intraerythrocytic Developmental Cycle of Plasmodium falciparum
2003 Standout
High throughput docking for library design and library prioritization
2001
Cysteine proteases of parasitic organisms
2002
Differences in substrate specificities between cysteine protease CPB isoforms of Leishmania mexicana are mediated by a few amino acid changes
2004 StandoutNobel
Data-Mining Approaches Reveal Hidden Families of Proteases in the Genome of Malaria Parasite
2003
Folding funnels and binding mechanisms
1999
Toxicity of cationic lipids and cationic polymers in gene delivery
2006 Standout
Extracellular matrix structure
2015 Standout
Constraining Cyclic Peptides To Mimic Protein Structure Motifs
2014
The development of allergic inflammation
2008 StandoutNature
Formation of Plasmid-Based Transfection Complexes with an Acid-Labile Cationic Lipid: Characterization of in Vitro and in Vivo Gene Transfer
2002
Predicting Drug‐Resistant Mutations of HIV Protease
2007 StandoutNobel
Small-molecule inhibitors of protein–protein interactions: progressing towards the dream
2004 Standout
Mechanisms of drug combinations: interaction and network perspectives
2009 Standout
Multiple diverse ligands binding at a single protein site: A matter of pre‐existing populations
2002
Aggregation-induced emission: phenomenon, mechanism and applications
2009 Standout
Artemisinin, an Endoperoxide Antimalarial, Disrupts the Hemoglobin Catabolism and Heme Detoxification Systems in Malarial Parasite
1999
Very fast prediction and rationalization of pKa values for protein–ligand complexes
2008
Endoplasmic Reticulum PI(3)P Lipid Binding Targets Malaria Proteins to the Host Cell
2012
Antimalarial drug synergism and antagonism: Mechanistic and clinical significance
2005
Design, docking, and evaluation of multiple libraries against multiple targets
2001
Expression and characterization of a recombinant cysteine proteinase of Leishmania mexicana
2000 StandoutNobel
Hydrolysis of erythrocyte proteins by proteases of malaria parasites
2002
Conformational switching in an aspartic proteinase
1998
Access to Hematin: The Basis of Chloroquine Resistance
1998
Antimicrobial reactive oxygen and nitrogen species: concepts and controversies
2004 Standout
Starving the Malaria Parasite: Inhibitors Active against the Aspartic Proteases Plasmepsins I, II, and IV
2006
Renin inhibition by substituted piperidines: A novel paradigm for the inhibition of monomeric aspartic proteinases?
1999
Mutations in the P. falciparum Digestive Vacuole Transmembrane Protein PfCRT and Evidence for Their Role in Chloroquine Resistance
2000 Standout
Gold Nanorods: From Synthesis and Properties to Biological and Biomedical Applications
2009 Standout
Creation of a zymogen
2002
Controlled Microwave Heating in Modern Organic Synthesis
2004 Standout
Structure–activity studies of cyclic ketone inhibitors of the serine protease plasmin: Design, synthesis, and biological activity
2006
Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm
2006 Standout
Organic Azides: An Exploding Diversity of a Unique Class of Compounds
2005 Standout
Yeast and mammalian autophagosomes exhibit distinct phosphatidylinositol 3-phosphate asymmetries
2014 StandoutNobel
Free Energy Calculations and Ligand Binding
2003
Time-tagged ticker tapes for intracellular recordings
2023 StandoutNobel
Validating the vitality strategy for fighting drug resistance
2011 StandoutNobel
Coordinating Radiometals of Copper, Gallium, Indium, Yttrium, and Zirconium for PET and SPECT Imaging of Disease
2010 Standout
Human and Parasitic Papain-Like Cysteine Proteases: Their Role in Physiology and Pathology and Recent Developments in Inhibitor Design
2002
Aushungern des Malaria‐Erregers: Hemmer der Aspartylproteasen Plasmepsin I, II und IV
2006
New Insights on Classification, Identification, and Clinical Relevance ofBlastocystisspp
2008 Standout
Cooperative domains define a unique host cell-targeting signal in Plasmodium falciparum -infected erythrocytes
2003
Luminescent Chemodosimeters for Bioimaging
2012 Standout
Structure-Based Drug Design: Exploring the Proper Filling of Apolar Pockets at Enzyme Active Sites
2008
Peptidic degron for IMiD-induced degradation of heterologous proteins
2019 StandoutNobel
General Solid-Phase Synthesis Approach To Prepare Mechanism-Based Aspartyl Protease Inhibitor Libraries. Identification of Potent Cathepsin D Inhibitors
1998
Antimalarial effects of vinyl sulfone cysteine proteinase inhibitors
1996
Nonviral Vectors for Gene Delivery
2008 Standout
Docking and scoring in virtual screening for drug discovery: methods and applications
2004 Standout
Inhibition of Heme Detoxification Processes Underlies the Antimalarial Activity of Terpene Isonitrile Compounds from Marine Sponges
2001
Synthesis, Structure, and Anticancer Activity of Gallium(III) Complexes with Asymmetric Tridentate Ligands: Growth Inhibition and Apoptosis Induction of Cisplatin-Resistant Neuroblastoma Cells
2006
Improved Treatment of Ligands and Coupling Effects in Empirical Calculation and Rationalization of pKa Values
2011
PROPKA3: Consistent Treatment of Internal and Surface Residues in Empirical pKaPredictions
2011 Standout
Parasite proteinases and amino acid metabolism: possibilities for chemotherapeutic exploitation
1997
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Molecular Docking: Shifting Paradigms in Drug Discovery
2019 Standout
Update 1 of: Proteases Universally Recognize Beta Strands In Their Active Sites
2010
Quantification of labile heme in live malaria parasites using a genetically encoded biosensor
2017
De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures
2017 StandoutNobel
Microwave-Assisted Synthesis in Water as Solvent
2007 Standout
High-Speed Optimization of Inhibitors of the Malarial Proteases Plasmepsin I and II
2003
Plasmodium Hemozoin Formation Mediated by Histidine-Rich Proteins
1996 Science
Protease Inhibitors: Current Status and Future Prospects
2000
Solid-Phase Library Synthesis, Screening, and Selection of Tight-Binding Reduced Peptide Bond Inhibitors of a RecombinantLeishmaniamexicanaCysteine Protease B
2002 StandoutNobel
A general strategy to construct small molecule biosensors in eukaryotes
2015 StandoutNobel
Advances in Copper Complexes as Anticancer Agents
2013 Standout
Visible‐Light Photocatalysis: Does It Make a Difference in Organic Synthesis?
2018 Standout
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
HEMOGLOBIN METABOLISM IN THE MALARIA PARASITEPLASMODIUM FALCIPARUM
1997
Stapled β-Hairpins Featuring 4-Mercaptoproline
2021 StandoutNobel
Structure and Mechanism of the Pepsin-Like Family of Aspartic Peptidases
2002
A Medicinal Chemist’s Guide to Molecular Interactions
2010 Standout
New Innovations for an Old Infection: Antimalarial Lead Discovery from Marine Natural Products During the Period 2003–2008
2009
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
g_mmpbsa—A GROMACS Tool for High-Throughput MM-PBSA Calculations
2014 Standout
Host-targeting protein 1 (SpHtp1) from the oomycete Saprolegnia parasitica translocates specifically into fish cells in a tyrosine-O-sulphate–dependent manner
2012
Potent, Low-Molecular-Weight Non-Peptide Inhibitors of Malarial Aspartyl Protease Plasmepsin II
1999
PROTEASES IN PARASITIC DISEASES
2006
Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design
2011 Standout
Mononuclear six-coordinated Ga(III) complexes: A comprehensive survey
2008
Works of Anna Oksman being referenced
Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway.
1994
Synthesis, characterization, and molecular structure of a gallium(III) complex of an amine-phenol ligand with activity against chloroquine-sensitive Plasmodium falciparum strains
2003
trans Expression of a Plasmodium falciparum Histidine-rich Protein II (HRPII) Reveals Sorting of Soluble Proteins in the Periphery of the Host Erythrocyte and Disrupts Transport to the Malarial Food Vacuole
2002
Plasmepsin V licenses Plasmodium proteins for export into the host erythrocyte
2010 Nature
Identification of potent inhibitors of Plasmodium falciparum plasmepsin II from an encoded statine combinatorial library
1998
Transfer of genes into Plasmodium falciparum by polyamidoamine dendrimers
1999
Probing the Chloroquine Resistance Locus of Plasmodium falciparum with a Novel Class of Multidentate Metal(III) Coordination Complexes
1997
Metalloantimalarials: Targeting of P. falciparum Strains with Novel Iron(III) and Gallium(III) Complexes of an Amine Phenol Ligand
2003
Asparagine repeat function in a Plasmodium falciparum protein assessed via a regulatable fluorescent affinity tag
2011
A calpain unique to alveolates is essential in Plasmodium falciparum and its knockdown reveals an involvement in pre-S-phase development
2009
Structure and inhibition of plasmepsin II, a hemoglobin-degrading enzyme from Plasmodium falciparum.
1996
Molecular characterization and inhibition of a Plasmodium falciparum aspartic hemoglobinase.
1994
Malaria parasite exit from the host erythrocyte: A two-step process requiring extraerythrocytic proteolysis
2000