Citation Impact
Citing Papers
You say lipofuscin, we say ceroid: Defining autofluorescent storage material
2006
Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism
2024 StandoutNobel
Three Classes of Inhibitors Share a Common Binding Domain in Mitochondrial Complex I (NADH:Ubiquinone Oxidoreductase)
1999
Chapter 5 Assaying mitochondrial respiratory complex activity in mitochondria isolated from human cells and tissues
2001
Twinkle mutations associated with autosomal dominant progressive external ophthalmoplegia lead to impaired helicase function and in vivo mtDNA replication stalling
2008
Animal mitochondrial genomes
1999 Standout
The Complex I from Rhodobacter capsulatus
1998
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Rac1 Activity Is Required for the Activation of Hypoxia-inducible Factor 1
2001 StandoutNobel
Diagnostic challenges of mitochondrial DNA disorders
2006
Inhibitors of NADH–ubiquinone reductase: an overview
1998
Inclusion body myositis and myopathies
1995 Standout
Diphenyleneiodonium, an NAD(P)H Oxidase Inhibitor, also Potently Inhibits Mitochondrial Reactive Oxygen Species Production
1998
Electron Transport Chain Defects in Heart Failure
2002
The bacterial energy-transducing NADH-quinone oxidoreductases
1993
Mitochondria: Dynamic Organelles in Disease, Aging, and Development
2006 Standout
Neuropathological and Histochemical Changes in a Multiple Mitochondrial DNA Deletion Disorder
2000
Decrease of 3243 A→G mtDNA Mutation from Blood in MELAS Syndrome: A Longitudinal Study
2001
Reactive Oxygen Species Generated at Mitochondrial Complex III Stabilize Hypoxia-inducible Factor-1α during Hypoxia
2000 Standout
The Failing Heart — An Engine Out of Fuel
2007 Standout
Segregation of the ND4/11778 and the ND1/3460 mutations in four heteroplasmic LHON families
2002
Organization and evolution of structural elements within complex I
1998
Mitochondrial Respiratory-Chain Diseases
2003
The F420H2 Dehydrogenase fromMethanosarcina mazei Is a Redox-driven Proton Pump Closely Related to NADH Dehydrogenases
2000
An artificial molecular pump
2015 StandoutNobel
Mitochondrial diabetes mellitus: a review
1995
Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology
2015 Standout
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
The Origin of Cluster N2 of the Energy-Transducing NADH–Quinone Oxidoreductase: Comparisons of Phylogenetically Related Enzymes
2001
A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology
2008 Standout
Abnormal cardiac and skeletal muscle mitochondrial function in pacing-induced cardiac failure
2001
Pancreatic cancer
2016 Standout
Mitochondrial DNA polymerase-γ and human disease
2006
An autosomal locus predisposing to deletions of mitochondrial DNA
1995
Thymidine kinase 2 mutations in autosomal recessive progressive external ophthalmoplegia with multiple mitochondrial DNA deletions
2011
Ca2+/Calmodulin Kinase-dependent Activation of Hypoxia Inducible Factor 1 Transcriptional Activity in Cells Subjected to Intermittent Hypoxia
2004 StandoutNobel
[2] Structural analysis of NADH: Ubiquinone oxidoreductase from bovine heart mitochondria
1995 StandoutNobel
Novel reactions involved in energy conservation by methanogenic archaea
1999
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Mitochondria: In Sickness and in Health
2012 Standout
Evidence for a quinone binding site close to the interface between NUOD and NUOB subunits of Complex I
2001
Optimal Determination of Particle Orientation, Absolute Hand, and Contrast Loss in Single-particle Electron Cryomicroscopy
2003 StandoutNobel
Role of NAD(P)H oxidase in the regulation of cardiac L-type Ca channel function during acute hypoxia
2005
Mood and Anxiety Disorders as Early Manifestations of Medical Illness: A Systematic Review
2014
Parkinsonism, premature menopause, and mitochondrial DNA polymerase γ mutations: clinical and molecular genetic study
2004
Finding twinkle in the eyes of a 71‐year‐old lady: A case report and review of the genotypic and phenotypic spectrum of TWINKLE‐related dominant disease
2009
The NADH:ubiquinone oxidoreductase (complex I) of respiratory chains
1992 StandoutNobel
A giant molecular proton pump: structure and mechanism of respiratory complex I
2015
Understanding the Odd Science of Aging
2005 Standout
The NADPH oxidase of professional phagocytes—prototype of the NOX electron transport chain systems
2004
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
Sequences of 20 subunits of NADH: Ubiquinone oxidoreductase from bovine heart mitochondria
1992 StandoutNobel
Clustering of Alpers disease mutations and catalytic defects in biochemical variants reveal new features of molecular mechanism of the human mitochondrial replicase, Pol γ
2011
Toward a Characterization of the Connecting Module of Complex I
2001
Bovine Complex I Is a Complex of 45 Different Subunits
2006 Nobel
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
2006 StandoutNature
Recent developments in the molecular genetics of mitochondrial disorders
1998
Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism☆
2009
Mitochondrial dysfunction as a cause of optic neuropathies
2004
Searching for genes affecting the structural integrity of the mitochondrial genome
1995
Activation of an H2O2-generating NADH Oxidase in Human Lung Fibroblasts by Transforming Growth Factor β1
1995
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Mitochondrial myopathy induces a starvation-like response
2010
The Hallmarks of Aging
2013 Standout
Conservation of sequences of subunits of mitochondrial complex I and their relationships with other proteins
1992 StandoutNobel
Physiological Roles of Mitochondrial Reactive Oxygen Species
2012 Standout
Polymyositis and dermatomyositis
2003 Standout
Up-regulation of Apoptosis Inhibitory Protein IAP-2 by Hypoxia
2001 StandoutNobel
p22 Is a Critical Component of the Superoxide-generating NADH/NADPH Oxidase System and Regulates Angiotensin IIinduced Hypertrophy in Vascular Smooth Muscle Cells
1996
Metabolic cardiomyopathies
2000
Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
2016 Standout
Voltage-Gated Proton Channels and Other Proton Transfer Pathways
2003
Clues from cell metabolism
2010 StandoutNatureNobel
Familial multisystem degeneration with parkinsonism associated with the 11778 mitochondrial DNA mutation
1999
Mutant mitochondrial helicase Twinkle causes multiple mtDNA deletions and a late-onset mitochondrial disease in mice
2005
Role of Oxidants in NF-κB Activation and TNF-α Gene Transcription Induced by Hypoxia and Endotoxin
2000
Three-dimensional structure of bovine NADH:ubiquinone oxidoreductase (complex I) at 22 å in ice
1998
DNA Polymerase γ in Mitochondrial DNA Replication and Repair
2005
Electron Transport Complex I Is Required for CD8+ T Cell Function
2006
Leber hereditary optic neuropathy mutations in the ND6 subunit of mitochondrial complex I affect ubiquinone reduction kinetics in a bacterial model of the enzyme
2007
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
2008 StandoutNature
Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain
2001 StandoutNobel
Occurrence, Classification, and Biological Function of Hydrogenases: An Overview
2007 Standout
PROLINE HYDROXYLATION AND GENE EXPRESSION
2005 StandoutNobel
An anthelmintic compound, nafuredin, shows selective inhibition of complex I in helminth mitochondria
2000 StandoutNobel
ROS-based lethality of Caenorhabditis elegans mitochondrial electron transport mutants grown on Escherichia coli siderophore iron release mutants
2019 StandoutNobel
Surfactant Protein D Regulates NF-κB and Matrix Metalloproteinase Production in Alveolar Macrophages via Oxidant-Sensitive Pathways
2001
Fluorescence Lifetime Measurements and Biological Imaging
2010 Standout
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Use of Transmitochondrial Cybrids To Assign a Complex I Defect to the Mitochondrial DNA-Encoded NADH Dehydrogenase Subunit 6 Gene Mutation at Nucleotide Pair 14459 That Causes Leber Hereditary Optic Neuropathy and Dystonia
1996
Review: Mitochondrial medicine--cardiomyopathy caused by defective oxidative phosphorylation.
2003
Somatic Progenitor Cell Vulnerability to Mitochondrial DNA Mutagenesis Underlies Progeroid Phenotypes in Polg Mutator Mice
2012
Oxidative Damage to Mitochondrial Complex I Due to Peroxynitrite
2003 Nobel
Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery
2013
Mitochondrial Diseases in Man and Mouse
1999 StandoutScience
Model for Hypoxic Pulmonary Vasoconstriction Involving Mitochondrial Oxygen Sensing
2001
Large-scale chromatographic purification of F1F0-ATPase and complex I from bovine heart mitochondria
1996 StandoutNobel
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Effect of bezafibrate treatment on late-onset mitochondrial myopathy in mice
2011
Energy Converting NADH: Quinone Oxidoreductase (Complex I)
2006
Mitochondrial Dysfunction and Type 2 Diabetes
2005 StandoutScience
Mouse models of mitochondrial DNA defects and their relevance for human disease
2009
The development of mitochondrial medicine.
1994
Synthesis and Inhibition Mechanism of Δlac-Acetogenins, a Novel Type of Inhibitor of Bovine Heart Mitochondrial Complex I
2004
A Key Role for Redox Signaling in Rapid P2X7 Receptor-Induced IL-1β Processing in Human Monocytes
2008
The Mononuclear Molybdenum Enzymes
2014 Standout
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet
2011 StandoutNobel
Expression of a Functionally Active gp91phox-Containing Neutrophil-Type NAD(P)H Oxidase in Smooth Muscle Cells From Human Resistance Arteries
2002
HIF-1 and human disease: one highly involved factor
2000 StandoutNobel
Ketogenic diet slows down mitochondrial myopathy progression in mice
2010
Free Radicals in the Physiological Control of Cell Function
2002 Standout
Proton-Coupled Electron Transfer
2012 Standout
Works of Anna Majander being referenced
Electron transfer properties of NADH: Ubiquinone reductase in the ND1/3460 and the ND4/11778 mutations of the Leber hereditary optic neuroretinopathy (LHON)
1991
Catalytic Activity of Complex I in Cell Lines that Possess Replacement Mutations in the ND Genes in Leber's Hereditary Optic Neuropathy
1996
Multiple deletions of mitochondrial DNA in several tissues of a patient with severe retarded depression and familial progressive external ophthalmoplegia.
1992
Inherited idiopathic dilated cardiomyopathy with multiple deletions of mitochondrial DNA
1992
Congenital Hypoplastic Anemia, Diabetes, and Severe Renal Tubular Dysfunction Associated with a Mitochondrial DNA Deletion
1991
The plasma membrane potential of human neutrophils. Role of ion channels and the sodium/potassium pump
1989
Diagnosis of fatal infantile defects of the mitochondrial respiratory chain: age dependence and postmortem analysis of enzyme activities
1995
Isolation and Characterisation of Subcomplexes of the Mitochondrial NADH: Ubiquinone Oxidoreductase (Complex I)
1994
Correlation between the Clinical Symptoms and the Proportion of Mitochondrial DNA Carrying the 8993 Point Mutation in the NARP Syndrome
1995
Palmitate oxidation in muscle mitochondria of patients with the juvenile form of neuronal ceroid‐lipofuscinosis
1995
ATP, phosphocreatine and lactate in exercising muscle in mitochondrial disease and McArdle’s disease
2001
Studies on the proton‐translocating NADH:ubiquinone oxidoreductases of mitochondria and Escherichia coli using the inhibitor 1,10‐phenanthroline
1994
Quantification of tRNA3243Leu point mutation of mitochondrial DNA in MELAS patients and its effects on mitochondrial transcription
1993
Autosomal dominant progressive external ophthalmoplegia with multiple deletions of mtDNA
1997
Diphenyleneiodonium inhibits reduction of iron-sulfur clusters in the mitochondrial NADH-ubiquinone oxidoreductase (Complex I).
1994