Standout Papers

Do no harm: a roadmap for responsible machine learning for health care 2019 2026 2021 2023 433
  1. Do no harm: a roadmap for responsible machine learning for health care (2019)
    Jenna Wiens, Suchi Saria et al. Nature Medicine

Citation Impact

Citing Papers

rMATS: Robust and flexible detection of differential alternative splicing from replicate RNA-Seq data
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HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing
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deepNF: deep network fusion for protein function prediction
2018
A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension
2019 StandoutNobel
A survey of best practices for RNA-seq data analysis
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Blind spots of quantitative RNA-seq: the limits for assessing abundance, differential expression, and isoform switching
2013
Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension
2011 StandoutNobel
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Rac1 Activity Is Required for the Activation of Hypoxia-inducible Factor 1
2001 StandoutNobel
C. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
2001 StandoutNobel
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
2020 Standout
Oxygen sensing and signal transduction in hypoxic pulmonary vasoconstriction
2015
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Detecting influenza epidemics using search engine query data
2008 StandoutNature
StringTie enables improved reconstruction of a transcriptome from RNA-seq reads
2015 Standout
A paradigm shift in medicine: A comprehensive review of network-based approaches
2019
Reactive Oxygen Species Generated at Mitochondrial Complex III Stabilize Hypoxia-inducible Factor-1α during Hypoxia
2000 Standout
Animal models of chronic obstructive pulmonary disease
2008
Foundation models for generalist medical artificial intelligence
2023 StandoutNature
STRING v10: protein–protein interaction networks, integrated over the tree of life
2014 Standout
Cancer Cell Metabolism: Warburg and Beyond
2008 Standout
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
Divergent roles of reactive oxygen species in the responses of perinatal adrenal chromaffin cells to hypoxic challenges
2010
AI in health and medicine
2022 Standout
xCell: digitally portraying the tissue cellular heterogeneity landscape
2017 Standout
Ca2+/Calmodulin Kinase-dependent Activation of Hypoxia Inducible Factor 1 Transcriptional Activity in Cells Subjected to Intermittent Hypoxia
2004 StandoutNobel
HIF-1, O2, and the 3 PHDs
2001 StandoutNobel
The STRING database in 2017: quality-controlled protein–protein association networks, made broadly accessible
2016 Standout
Scleroderma
2009 Standout
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes
2015 StandoutNobel
On the association of succinate dehydrogenase mutations with hereditary paraganglioma
2003
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-α prolyl hydroxylase
2005 Standout
Hypoxic induction of hypoxia-inducible factor-1α and oxygen-regulated gene expression in mitochondrial DNA-depleted HeLa cells
2002
Hypoxia-inducible Factor (HIF) Asparagine Hydroxylase Is Identical to Factor Inhibiting HIF (FIH) and Is Related to the Cupin Structural Family
2002 StandoutNobel
Language models are an effective representation learning technique for electronic health record data
2020
Hypoxia-inducible factor-1-dependent mechanisms of vascularization and vascular remodelling
2010 StandoutNobel
Role of oxidative stress in intermittent hypoxia‐induced immediate early gene activation in rat PC12 cells
2004
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
Selection of Mutant CHO Cells with Constitutive Activation of the HIF System and Inactivation of the von Hippel-Lindau Tumor Suppressor
2001 StandoutNobel
Adenovirus-mediated HIF-1α gene transfer promotes repair of mouse airway allograft microvasculature and attenuates chronic rejection
2011 StandoutNobel
Network propagation: a universal amplifier of genetic associations
2017
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
Independent function of two destruction domains in hypoxia-inducible factor-α chains activated by prolyl hydroxylation
2001 StandoutNobel
Upregulation of NAD(P)H oxidase 1 in hypoxia activates hypoxia-inducible factor 1 via increase in reactive oxygen species
2004
Up-regulation of Apoptosis Inhibitory Protein IAP-2 by Hypoxia
2001 StandoutNobel
Methods to Study Splicing from High-Throughput RNA Sequencing Data
2014
Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
2016 Standout
Next-Generation Machine Learning for Biological Networks
2018
Assessment of transcript reconstruction methods for RNA-seq
2013
MITIE: Simultaneous RNA-Seq-based transcript identification and quantification in multiple samples
2013
Mammalian Oxygen Sensing, Signalling and Gene Regulation
2000
Molecular mechanisms of hypoxia‐inducible factor‐induced pulmonary arterial smooth muscle cell alterations in pulmonary hypertension
2015
Telephone triage: a timely data source for surveillance of influenza-like diseases.
2003
Regulation of hypoxia-inducible factor is preserved in the absence of a functioning mitochondrial respiratory chain
2001 StandoutNobel
Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor
2002 StandoutNobel
Exactp-Values for Network Interference
2016 StandoutNobel
PROLINE HYDROXYLATION AND GENE EXPRESSION
2005 StandoutNobel
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Hypoxia-Inducible Factor 1 and Cardiovascular Disease
2013 StandoutNobel
STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
2018 Standout
Metabolic reprogramming and cancer progression
2020 StandoutScience
Network Medicine Framework for Identifying Drug Repurposing Opportunities for COVID-19
2020
Targeting tumors through the HIF system
2000 StandoutNobel
GeneMANIA Prediction Server 2013 Update
2013
HIF-1 and human disease: one highly involved factor
2000 StandoutNobel
The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets
2020 Standout
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart
2013 StandoutNobel
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
GeneMANIA update 2018
2018

Works of Anna Goldenberg being referenced

Hypoxic vasoconstriction of partial muscular intra-acinar pulmonary arteries in murine precision cut lung slices
2006
Rapamycin attenuates hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy in mice
2007
Incorporating networks in a probabilistic graphical model to find drivers for complex human diseases
2017
Predicting Node Characteristics from Molecular Networks
2011
Hypoxic upregulation of tyrosine hydroxylase gene expression is paralleled, but not induced, by increased generation of reactive oxygen species in PC12 cells
1999
Do no harm: a roadmap for responsible machine learning for health care
2019 Standout
Machine learning for integrating data in biology and medicine: Principles, practice, and opportunities
2018
Subcellular Localization and Function of B-Type Cytochromes in Carotid Body and Other Paraganglionic Cells
2002
Similarity network fusion for aggregating data types on a genomic scale
2014
Impact of Modulators of Mitochondrial ATP-Sensitive Potassium Channel (mitoKATP) on Hypoxic Pulmonary Vasoconstriction
2009
Labeling Nodes Using Three Degrees of Propagation
2012
iReckon: Simultaneous isoform discovery and abundance estimation from RNA-seq data
2012
Mitochondrial complex II is essential for hypoxia-induced pulmonary vasoconstriction of intra- but not of pre-acinar arteries
2012
A Survey of Statistical Network Models
2010
Early statistical detection of anthrax outbreaks by tracking over-the-counter medication sales
2002
Essential role of complex II of the respiratory chain in hypoxia-induced ROS generation in the pulmonary vasculature
2003
PharmacoGx: an R package for analysis of large pharmacogenomic datasets
2015
Intermedin/adrenomedullin-2 is a hypoxia-induced endothelial peptide that stabilizes pulmonary microvascular permeability
2009
Rankless by CCL
2026