Citation Impact
Citing Papers
Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia
2004 StandoutScience
Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcription
2007
Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron
2007
Notch signalling controls pancreatic cell differentiation
1999 StandoutNatureNobel
Functional Interaction between SEL-10, an F-box Protein, and the Nuclear Form of Activated Notch1 Receptor
2001 StandoutNobel
Combined Loss of Hey1 and HeyL Causes Congenital Heart Defects Because of Impaired Epithelial to Mesenchymal Transition
2007
Striking Oxygen Sensitivity of the Peptidylglycine α-Amidating Monooxygenase (PAM) in Neuroendocrine Cells
2015 StandoutNobel
Notch and neurogenesis
1998
Notch signaling and inherited disease syndromes
2003
Purification and functional characterization of the human N-CoR complex: the roles of HDAC3, TBL1 and TBLR1
2003
Biological functions of fucose in mammals
2017
An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation
2007
NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21
2006 StandoutNature
Proteolytic Processing of Amyloid-β Precursor Protein by Secretases Does Not Require Cell Surface Transport
2004 StandoutNobel
Autoregulation of NFATc1/A Expression Facilitates Effector T Cells to Escape from Rapid Apoptosis
2002
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Vascularized and functional human liver from an iPSC-derived organ bud transplant
2013 StandoutNature
Mutations in VKORC1 cause warfarin resistance and multiple coagulation factor deficiency type 2
2004 StandoutNature
Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1
2001 StandoutNature
NFAT Signaling
2002
Microcephaly Modeling of Kinetochore Mutation Reveals a Brain-Specific Phenotype
2018
Calcineurin Promotes Hypoxia-inducible Factor 1α Expression by Dephosphorylating RACK1 and Blocking RACK1 Dimerization
2007 StandoutNobel
Transcriptional regulation by calcium, calcineurin, and NFAT
2003 Standout
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses
2012 StandoutNobel
The dynamic protein Knl1 – a kinetochore rendezvous
2014
Molecular Mechanism of Liver Development and Regeneration
2007
Natural Selection in the Great Apes
2016
Structural Basis for Cooperativity in Recruitment of MAML Coactivators to Notch Transcription Complexes
2006
Calcium signaling in systemic lupus erythematosus T cells: A treatment target
2011
CADASIL: A Critical Look at a Notch Disease
2006
Embryonic development of the liver†
2005
A genetic blueprint for cardiac development
2000 Nature
A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function
2006 StandoutNature
Target cell movement in tumor and cardiovascular diseases based on the epithelial–mesenchymal transition concept
2011
Mapping Sites of O-Glycosylation and Fringe Elongation on Drosophila Notch
2016
Modulation of Notch Signaling by Antibodies Specific for the Extracellular Negative Regulatory Region of NOTCH3
2008
Signaling—2000 and Beyond
2000 Standout
Systemic Lupus Erythematosus
2011 Standout
Functional Interaction between the Mouse Notch1 Intracellular Region and Histone Acetyltransferases PCAF and GCN5
2000 StandoutNobel
Osteoclast differentiation and activation
2003 StandoutNature
OSM-11 Facilitates LIN-12 Notch Signaling during Caenorhabditis elegans Vulval Development
2008
EMT: 2016
2016 Standout
Asparaginyl Hydroxylation of the Notch Ankyrin Repeat Domain by Factor Inhibiting Hypoxia-inducible Factor
2007 StandoutNobel
Long-Term Expansion of Functional Mouse and Human Hepatocytes as 3D Organoids
2018 StandoutNobel
Implication of APP Secretases in Notch Signaling
2001
Mouse hesr1 and hesr2 genes are redundantly required to mediate Notch signaling in the developing cardiovascular system
2004
The hormone resistin links obesity to diabetes
2001 StandoutNature
Drosophila Clock Can Generate Ectopic Circadian Clocks
2003 StandoutNobel
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5
2003 StandoutNature
Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease
2012
p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
1999 StandoutNature
Learning and Memory Deficits in Notch Mutant Mice
2003 StandoutNobel
Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells
2004 StandoutNobel
Synthetic glycopeptides and glycoproteins as tools for biology
2004 StandoutNobel
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
The mouse slalom mutant demonstrates a role for Jagged1 in neuroepithelial patterning in the organ of Corti
2001
Stem/Progenitor Cells in Liver Development, Homeostasis, Regeneration, and Reprogramming
2014
O-Glycosylation of EGF repeats: identification and initial characterization of a UDP-glucose: protein O-glucosyltransferase
2002
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
2009 Standout
Macrophage biology in development, homeostasis and disease
2013 StandoutNature
Sharp, an inducible cofactor that integrates nuclear receptor repression and activation
2001
Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesis
2003 StandoutNature
Mutational and Energetic Studies of Notch1 Transcription Complexes
2007
Large Scale Gene Expression Analysis of Osteoclastogenesisin Vitro and Elucidation of NFAT2 as a Key Regulator
2002
Induction and Activation of the Transcription Factor NFATc1 (NFAT2) Integrate RANKL Signaling in Terminal Differentiation of Osteoclasts
2002 Standout
Atherosclerosis
2001 Standout
FIH-1: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity
2001 StandoutNobel
Identification of High-Molecular-Weight Proteins with Multiple EGF-like Motifs by Motif-Trap Screening
1998
Rumi Is a CAP10 Domain Glycosyltransferase that Modifies Notch and Is Required for Notch Signaling
2008
Organogenesis and Development of the Liver
2010
Organoid single-cell genomic atlas uncovers human-specific features of brain development
2019 StandoutNatureNobel
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
Notch1 and Notch3 Instructively Restrict bFGF-Responsive Multipotent Neural Progenitor Cells to an Astroglial Fate
2001 StandoutNobel
Notch Ligands Are Substrates for ProteinO-Fucosyltransferase-1 and Fringe
2002
Notch receptor cleavage depends on but is not directly executed by presenilins
2002 StandoutNobel
A segment of cold shock protein directs the folding of a combinatorial protein
2005 StandoutNobel
Epithelial-mesenchymal transitions: insights from development
2012
Two Distinct Notch1 Mutant Alleles Are Involved in the Induction of T-Cell Leukemia in c-myc Transgenic Mice
2000
The Genetics of Primary Microcephaly
2018
Gene Regulatory Networks and the Evolution of Animal Body Plans
2006 StandoutScience
The coregulator exchange in transcriptional functions of nuclear receptors
2000 Standout
Introns in gene evolution
2003
Isolation of a novel histone deacetylase reveals that class I and class II deacetylases promote SMRT-mediated repression
2000
Signaling circuitries in development: insights from the retinal determination gene network
2004
Longer metaphase and fewer chromosome segregation errors in modern human than Neanderthal brain development
2022 StandoutNobel
Signalling interactions during facial development
1998
Binding of F-spondin to amyloid-β precursor protein: A candidate amyloid-β precursor protein ligand that modulates amyloid-β precursor protein cleavage
2004 StandoutNobel
Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members
2001 StandoutNobel
The Notch ligand Jagged1 is required for inner ear sensory development
2001
Calcium Depletion Dissociates and Activates Heterodimeric Notch Receptors
2000
The effects of conformational heterogeneity on the binding of the Notch intracellular domain to effector proteins: a case of biologically tuned disorder
2008
Msx2-interacting nuclear target protein (Mint) deficiency reveals negative regulation of early thymocyte differentiation by Notch/RBP-J signaling
2007 StandoutNobel
Nuclear receptor corepressors partner with class II histone deacetylases in a Sin3-independent repression pathway
2000
Introns in Gene Evolution
2003
Notch signaling: control of cell communication and cell fate
2004
Slug is a direct Notch target required for initiation of cardiac cushion cellularization
2008
CIR, a corepressor linking the DNA binding factor CBF1 to the histone deacetylase complex
1999
Notch Signaling: Cell Fate Control and Signal Integration in Development
1999 StandoutScience
Protein structure prediction for the male-specific region of the human Y chromosome
2004 StandoutNobel
The Drosophila eyes absent gene directs ectopic eye formation in a pathway conserved between flies and vertebrates
1997
Cellular Homeostasis and Repair in the Mammalian Liver
2015
Silencing of the Novel p53 Target Gene Snk/Plk2 Leads to Mitotic Catastrophe in Paclitaxel (Taxol)-Exposed Cells
2003
Chemical Glycoproteomics
2016 StandoutNobel
Recombination signal sequence-binding protein Jκ alters mesodermal cell fate decisions by suppressing cardiomyogenesis
2003 StandoutNobel
Endocardial Notch Signaling in Cardiac Development and Disease
2015
Works of Anna Genin being referenced
The Gene Encoding Human Nuclear Protein Tyrosine Phosphatase, PRL-1
1998
Prolonged expression of CD154 on CD4 T cells from pediatric lupus patients correlates with increased CD154 transcription, increased nuclear factor of activated T cell activity, and glomerulonephritis
2010
Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1
1997
Spectrum and Frequency of Jagged1 (JAG1) Mutations in Alagille Syndrome Patients and Their Families
1998
Kinetochore KMN network gene CASC5 mutated in primary microcephaly
2012
Mutations in the human Jagged1 gene are responsible for Alagille syndrome
1997
Jagged1 (JAG1) mutation detection in an Australian Alagille syndrome population
2000
Regulation of the Murine Nfatc1 Gene by NFATc2
2002
Homozygous deletion of the death receptor DR4 gene in a nasopharyngeal cancer cell line is associated with TRAIL resistance.
2000
Unique forms of human and mouse nuclear receptor corepressor SMRT
1999
Cloning and characterization of two vertebrate homologs of the Drosophila eyes absent gene.
1997