Standout Papers
Citation Impact
Citing Papers
Selective Activation of Adenosine A 2A Receptors on Immune Cells by a CD73-Dependent Prodrug Suppresses Joint Inflammation in Experimental Rheumatoid Arthritis
2012
The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic T reg Cell Homeostasis
2013 StandoutScience
A sex-biased imbalance between Tfr, Tph, and atypical B cells determines antibody responses in COVID-19 patients
2023 StandoutNobel
Construction of self-recognizing regulatory T cells from conventional T cells by controlling CTLA-4 and IL-2 expression
2013 StandoutNobel
CD39 deletion exacerbates experimental murine colitis and human polymorphisms increase susceptibility to inflammatory bowel disease
2009
The microbiota regulates type 2 immunity through RORγt + T cells
2015 StandoutScienceNobel
CD73-Deficient Mice Have Increased Antitumor Immunity and Are Resistant to Experimental Metastasis
2011
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
2013 StandoutScienceNobel
Hypoxia-inducible factor-1 alpha–dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa
2012
Cancer Exosomes Express CD39 and CD73, Which Suppress T Cells through Adenosine Production
2011
A2A Adenosine Receptor May Allow Expansion of T Cells Lacking Effector Functions in Extracellular Adenosine-Rich Microenvironments
2009
Human Circulating CD4+CD25highFoxp3+ Regulatory T Cells Kill Autologous CD8+ but Not CD4+ Responder Cells by Fas-Mediated Apoptosis
2009
Chimeric antigen receptor -T cell therapy: Applications and challenges in treatment of allergy and asthma
2019
FoxP3+ T regulatory cells in cancer: Prognostic biomarkers and therapeutic targets
2020
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
ENTPD1/CD39 is a promising therapeutic target in oncology
2012
Regulatory T-cell inhibition versus depletion: the right choice in cancer immunotherapy
2007
Adora2b Adenosine Receptor Engagement Enhances Regulatory T Cell Abundance during Endotoxin-Induced Pulmonary Inflammation
2012
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Cyclic AMP Represents a Crucial Component of Treg Cell-Mediated Immune Regulation
2016
Cellular function and molecular structure of ecto-nucleotidases
2012
Adenosine Receptors in Health and Disease
2011
Pannexin 1 channels facilitate communication between T cells to restrict the severity of airway inflammation
2021
Elevated Pre–Antiretroviral Therapy CD39+CD8+ T Cell Frequency Is Associated With Early Mortality in Advanced Human Immunodeficiency Virus/Tuberculosis Co-infection
2017 StandoutNobel
Nucleotide signalling during inflammation
2014 StandoutNature
Extracellular adenosine triphosphate and adenosine in cancer
2010
How many mechanisms do regulatory T cells need?
2008
Regulatory T cells and infection: a dangerous necessity
2007
Regulatory T Cells
2010
Enhancement of tumor immunotherapy by deletion of the A2A adenosine receptor
2011
Hypoxia and Inflammation
2011 Standout
Chimeric Antigen Receptor-Redirected Regulatory T Cells Suppress Experimental Allergic Airway Inflammation, a Model of Asthma
2017
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Cancer and the Immune System: Basic Concepts and Targets for Intervention
2015
Graft-versus-Host Disease Is Enhanced by Selective CD73 Blockade in Mice
2013
T regulatory cells: hypoxia-adenosinergic suppression and re-direction of the immune response
2009
Purinergic regulation of the immune system
2016
Antigen-specific Tregs control T cell responses against a limited repertoire of tumor antigens in patients with colorectal carcinoma
2009
Immune homeostasis enforced by co-localized effector and regulatory T cells
2015 Nature
Structural and functional features of central nervous system lymphatic vessels
2015 StandoutNature
CD39 Expression Identifies Terminally Exhausted CD8+ T Cells
2015
Orchestrated leukocyte recruitment to immune-privileged sites: absolute barriers versus educational gates
2013
Heme Oxygenase-1/Carbon Monoxide: From Basic Science to Therapeutic Applications
2006 Standout
Mechanisms of Foxp3+ T Regulatory Cell-Mediated Suppression
2009
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Oxidative stress controls regulatory T cell apoptosis and suppressor activity and PD-L1-blockade resistance in tumor
2017
Ectonucleotidases CD39 and CD73 on OvCA cells are potent adenosine-generating enzymes responsible for adenosine receptor 2A-dependent suppression of T cell function and NK cell cytotoxicity
2011
Regulatory T Cell-Derived Interleukin-10 Limits Inflammation at Environmental Interfaces
2008
PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer
2016 Standout
Targeting the hypoxia-adenosinergic signaling pathway to improve the adoptive immunotherapy of cancer
2013
CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation–mediated apoptosis of effector CD4+ T cells
2007
Immunity, Inflammation, and Cancer
2010 Standout
Regulatory T cells: how do they suppress immune responses?
2009 StandoutNobel
How regulatory T cells work
2008 Standout
Mechanism-driven biomarkers to guide immune checkpoint blockade in cancer therapy
2016 Standout
Cancer immunotherapy comes of age
2011 StandoutNature
The blockade of immune checkpoints in cancer immunotherapy
2012 Standout
Induction of T cell anergy: integration of environmental cues and infectious tolerance
2010
Adenosine receptors: therapeutic aspects for inflammatory and immune diseases
2008 Standout
Th17 and Regulatory T Cells in Mediating and Restraining Inflammation
2010
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses
2009 Nature
Divergent Cardiopulmonary Actions of Heme Oxygenase Enzymatic Products in Chronic Hypoxia
2009
FOXP3+ regulatory T cells in the human immune system
2010 StandoutNobel
Natural killer T cell dysfunction in CD39-null mice protects against concanavalin A–induced hepatitis
2008
Autocrine Adenosine Signaling Promotes Regulatory T Cell–Mediated Renal Protection
2012
The Foxp3+ regulatory T cell: a jack of all trades, master of regulation
2008
Immunomodulatory effects of deacetylase inhibitors: therapeutic targeting of FOXP3+ regulatory T cells
2009
Positive and negative influences of regulatory T cells on tumour immunity
2008
Caffeine promotes anti-tumor immune response during tumor initiation: Involvement of the adenosine A2A receptor
2015
CD39/Adenosine Pathway Is Involved in AIDS Progression
2011
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation
2013 StandoutNature
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy
2016 StandoutNobel
CD39/ENTPD1 Expression by CD4+Foxp3+ Regulatory T Cells Promotes Hepatic Metastatic Tumor Growth in Mice
2010
Regulatory T-Cell-Mediated Suppression of Conventional T-Cells and Dendritic Cells by Different cAMP Intracellular Pathways
2016
Purinergic Signaling during Inflammation
2012
Tumor-infiltrating regulatory T cells as targets of cancer immunotherapy
2023 StandoutNobel
2013
Digoxin inhibits development of hypoxic pulmonary hypertension in mice
2012 StandoutNobel
Computational design of a synthetic PD-1 agonist
2021 StandoutNobel
Detection of self-reactive CD8 + T cells with an anergic phenotype in healthy individuals
2014 StandoutScienceNobel
Adenosine and Hypoxia-Inducible Factor Signaling in Intestinal Injury and Recovery
2011
Regulatory T Cells: Mechanisms of Differentiation and Function
2007 Standout
Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3 high regulatory T cells in humans
2015 StandoutNobel
Immune cell regulation by autocrine purinergic signalling
2011
Immuno-Navigator, a batch-corrected coexpression database, reveals cell type-specific gene networks in the immune system
2016 StandoutNobel
PD-L1 negatively regulates CD4+CD25+Foxp3+ Tregs by limiting STAT-5 phosphorylation in patients chronically infected with HCV
2009
Inhibitory role of the transcription repressor Gfi1 in the generation of thymus-derived regulatory T cells
2013
Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
2016 StandoutNobel
Daratumumab depletes CD38+ immune regulatory cells, promotes T-cell expansion, and skews T-cell repertoire in multiple myeloma
2016
A2A receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells
2007
New Insights into the Molecular Basis of T Cell Anergy: Anergy Factors, Avoidance Sensors, and Epigenetic Imprinting
2009
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
ATP Inhibits the Generation and Function of Regulatory T Cells Through the Activation of Purinergic P2X Receptors
2011
Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis
2010
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Roles of Regulatory T Cell-Derived Extracellular Vesicles in Human Diseases
2022
Human CD4+CD39+ regulatory T cells produce adenosine upon co-expression of surface CD73 or contact with CD73+ exosomes or CD73+ cells
2014
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Unique potential of 4-1BB agonist antibody to promote durable regression of HPV + tumors when combined with an E6/E7 peptide vaccine
2015 StandoutNobel
The future of immune checkpoint therapy
2015 StandoutScienceNobel
The ectonucleotidases CD 39 and CD 73: Novel checkpoint inhibitor targets
2017
Precision glycocalyx editing as a strategy for cancer immunotherapy
2016 StandoutNobel
Adenosinergic Regulation of the Expansion and Immunosuppressive Activity of CD11b+Gr1+ Cells
2011
Epigenetic conversion of conventional T cells into regulatory T cells by CD28 signal deprivation
2020 StandoutNobel
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
CD39 is a promising therapeutic antibody target for the treatment of soft tissue sarcoma.
2015
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
2021 StandoutNobel
A Metabolic Immune Checkpoint: Adenosine in Tumor Microenvironment
2016
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Comprehensive Analysis of Frequency and Phenotype of T Regulatory Cells in HIV Infection: CD39 Expression of FoxP3+T Regulatory Cells Correlates with Progressive Disease
2010
Targeting Cancer-Derived Adenosine:New Therapeutic Approaches
2014
A distinct subpopulation of CD25−T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
Cancer immunotherapy using checkpoint blockade
2018 StandoutScience
Lys49 myotoxin from the Brazilian lancehead pit viper elicits pain through regulated ATP release
2017 StandoutNobel
CD73 + regulatory T cells contribute to adenosine‐mediated resolution of acute lung injury
2013
Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti–CTLA-4 antibody
2018 StandoutNobel
Works of Anna Erat being referenced
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
2007 Standout
Bilirubin
2005