Citation Impact
Citing Papers
Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice
1991 Standout
Elevated expression of M1 and M2 components and drug-induced posttranscriptional modulation of ribonucleotide reductase in a hydroxyurea-resistant mouse cell line
1987
Gene amplification in cancer
2006
Defects in a cell cycle checkpoint may be responsible for the genomic instability of cancer cells
1992 StandoutNobel
Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death
1996 Standout
The mammalian ultraviolet response is triggered by activation of src tyrosine kinases
1992
Activation of Atypical Protein Kinase C ζ by Caspase Processing and Degradation by the Ubiquitin-Proteasome System
2000 StandoutNobel
The chromosomal analysis of human solid tumors a triple challenge
1989
Adaptive enhancement and kinetics of nucleotide excision repair in humans
1999
hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization
1997 Standout
JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
1994 Standout
Telomere end-replication problem and cell aging
1992 StandoutNobel
Removal of psoralen monoadducts and crosslinks by human cell free extracts
1991 StandoutNobel
When Checkpoints Fail
1997 StandoutNobel
HIF-1α Induces Genetic Instability by Transcriptionally Downregulating MutSα Expression
2005 StandoutNobel
Tumor suppressor genes
1991 Standout
Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles
2010 StandoutNature
The stress-activated protein kinase subfamily of c-Jun kinases
1994 StandoutNature
The Regulation of AP-1 Activity by Mitogen-activated Protein Kinases
1995 Standout
Inhibition of N‐methyl‐N′'‐nitro‐n‐nitrosoguanidine‐induced methotrexate and adriamycin resistance in CHO cells by adeno‐associated virus type 2
1990 StandoutNobel
The Molecular Genetics of the Arsonate Idiotypic System of A/J Mice
1988
High resolution of human evolutionary trees with polymorphic microsatellites
1994 StandoutNature
Male breast cancer
2006 Standout
Evolution of chromosome bands: Molecular ecology of noncoding DNA
1989
The UV response involving the ras signaling pathway and AP-1 transcription factors is conserved between yeast and mammals
1994
Germline variable region gene segment derivation of human monoclonal anti-Rh(D) antibodies. Evidence for affinity maturation by somatic hypermutation and repertoire shift.
1992 StandoutNobel
Molecular themes in oncogenesis
1991 StandoutNobel
Neuroblastoma
2007 Standout
Disrupted dichotomous intracellular control of human papillomavirus infection in cancer of the cervix
1994 StandoutNobel
Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation
1991 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Recent progress in understanding mechanisms of mammalian DNA amplification
1989
The relationship between electromagnetic field and light exposures to melatonin and breast cancer risk: A review of the relevant literature
1999
DNA Repair Excision Nuclease Attacks Undamaged DNA
2001 StandoutNobel
Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
2009 Standout
Telomere length predicts replicative capacity of human fibroblasts.
1992 StandoutNobel
Comparative Genomic Hybridization for Molecular Cytogenetic Analysis of Solid Tumors
1992 StandoutScience
Structure and polymorphism of the mouse prion protein gene.
1994 StandoutNobel
A biomarker that identifies senescent human cells in culture and in aging skin in vivo.
1995 Standout
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.
1992 StandoutNobel
Consistent N-myc copy number in simultaneous or consecutive neuroblastoma samples from sixty individual patients.
1987
The PVT gene frequently amplifies with MYC in tumor cells.
1989 StandoutNobel
A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration.
1991
Cotransformation and Gene Targeting in Mouse Embryonic Stem Cells
1991 StandoutNobel
Hypoxia induces DNA overreplication and enhances metastatic potential of murine tumor cells.
1988
Gene-specific formation and repair of cisplatin intrastrand adducts and interstrand cross-links in Chinese hamster ovary cells.
1991 StandoutNobel
Mechanisms of DNA Excision Repair
1994 StandoutScienceNobel
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Co-amplified markers alternate in megabase long chromosomal inverted repeats and cluster independently in interphase nuclei at early steps of mammalian gene amplification.
1992
Activation of Protein Kinase C Triggers Its Ubiquitination and Degradation
1998
Increased Incidence of CAD Gene Amplification in Tumorigenic Rat Lines as an Indicator of Genomic Instability of Neoplastic Cells
1989
Replicative Senescence: the Human Fibroblast Comes of Age
1990 Science
Heterogeneity of nitrogen mustard-induced DNA damage and repair at the level of the gene in Chinese hamster ovary cells.
1990 StandoutNobel
Immune-Mediated Inhibition of Metastases after Treatment with Local Radiation and CTLA-4 Blockade in a Mouse Model of Breast Cancer
2005 StandoutNobel
Processing of psoralen adducts in an active human gene: Repair and replication of DNA containing monoadducts and interstrand cross-links
1987
Hamster cells with increased rates of DNA amplification, a new phenotype
1987
Cell and Environment Interactions in Tumor Microregions: The Multicell Spheroid Model
1988 StandoutScience
DNA amplification is rare in normal human cells.
1990
Oncogenes result in genomic alterations that activate a transcriptionally silent, dominantly selectable reporter gene (neo).
1992
DNA sequences that mediate attenuation of transcription from the mouse protooncogene myc.
1989 StandoutNobel
Persistence of Tandem Arrays: Implications for Satellite and Simple-Sequence DNAs
1987
Tumor cell instability, diversification, and progression to the metastatic phenotype: from oncogene to oncofetal expression.
1987
Effect of Damage Type on Stimulation of Human Excision Nuclease by SWI/SNF Chromatin Remodeling Factor
2003 StandoutNobel
Methotrexate resistance and gene amplification. Mechanisms and implications
1986
Highly specific and sensitive method for measuring nucleotide excision repair kinetics of ultraviolet photoproducts in human cells
2013 StandoutNobel
Drug-induced DNA hypermethylation and drug resistance in human tumors.
1989
Carcinogen-induced trans activation of gene expression.
1988
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
A weak germ-line excision mutation blocks developmentally controlled amplification of the rDNA minichromosome of Tetrahymena thermophila.
1994 StandoutNobel
Gene amplification in cultured cells.
1988
Cotransformation and gene targeting in mouse embryonic stem cells.
1991 StandoutNobel
Targeted homologous recombination at the endogenous adenine phosphoribosyltransferase locus in Chinese hamster cells.
1989
Oncogene Amplification in Tumor Cells
1986
High rate of CAD gene amplification in human cells deficient in MLH1 or MSH6
2001 StandoutNobel
Effects of DNA methylation on topoisomerase I and II cleavage activities.
1994 StandoutNobel
DNA amplification of adeno-associated virus as a response to cellular genotoxic stress.
1988
Tumorigenicity in Human Melanoma Cell Lines Controlled by Introduction of Human Chromosome 6
1990 Science
Initiation of DNA Interstrand Cross-Link Repair in Humans: the Nucleotide Excision Repair System Makes Dual Incisions 5′ to the Cross-linked Base and Removes a 22- to 28-Nucleotide-long Damage-Free Strand
1997 StandoutNobel
The Complete Nucleotide Sequence of the Human Immunoglobulin Heavy Chain Variable Region Locus
1998 StandoutNobel
Sister chromatid fusion initiates amplification of the dihydrofolate reductase gene in Chinese hamster cells.
1993
Replication of adeno-associated virus in synchronized cells without the addition of a helper virus
1987
Cancer-induced Defective Cytotoxic T Lymphocyte Effector Function: Another Mechanism How Antigenic Tumors Escape Immune-mediated Killing
2000
Gene Amplification in a p53-Deficient Cell Line Requires Cell Cycle Progression under Conditions That Generate DNA Breakage
1998
DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSα/hMutSβ ratio and reduces the efficiency of base–base mismatch repair
1997 StandoutNobel
Extension of Life-Span by Introduction of Telomerase into Normal Human Cells
1998 StandoutScience
Transient hypoxia enhances the frequency of dihydrofolate reductase gene amplification in Chinese hamster ovary cells.
1986
Works of Anna B. Hill being referenced
Effects of melatonin on the cell cycle kinetics and “estrogen‐rescue” of MCF‐7 human breast cancer cells in culture
1991
Transient inhibition of DNA synthesis results in increased dihydrofolate reductase synthesis and subsequent increased DNA content per cell.
1986
Increased gene amplification in L5178Y mouse lymphoma cells with hydroxyurea-induced chromosomal aberrations.
1985
MHC loss in colorectal tumours: evidence for immunoselection?
1992
Fifth Gordon Hamilton-Fairley memorial lecture. Methotrexate resistance and gene amplification: An experimental model for the generation of cellular heterogeneity
1985
Transient Inhibition of DNA sYnthesis Results in Increased Dihydrofolate Reductase Synthesis and Subsequent Increased DNA Content per Cell
1986
Overreplication and recombination of DNA in higher eukaryotes: potential consequences and biological implications.
1986
Effects of v-src Oncogene Activation on Radiation Sensitivity in Drug-Sensitive and in Multidrug-Resistant Rat Fibroblasts
1992
Possible relationship between chromosome alterations and radiosensitivity in human malignant melanoma
1989