Citation Impact
Citing Papers
Protein characterization of Saccharomyces cerevisiae RNA polymerase II after in vivo cross-linking
2007 StandoutNobel
Rtt109 Acetylates Histone H3 Lysine 56 and Functions in DNA Replication
2007 Science
Requirement of NAD and SIR2 for Life-Span Extension by Calorie Restriction in Saccharomyces cerevisiae
2000 StandoutScience
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
2009 StandoutScience
Regulation of Corepressor Function by Nuclear NADH
2002 Science
Induction of interferon-stimulated gene expression and antiviral responses require protein deacetylase activity
2004 StandoutNobel
Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines.
2003
Sirtuins as regulators of metabolism and healthspan
2012 Standout
An integrated encyclopedia of DNA elements in the human genome
2012 StandoutNature
From molecular to modular cell biology
1999 StandoutNatureNobel
SIRT1 Deacetylates and Positively Regulates the Nuclear Receptor LXR
2007
Characterization of the pufferfish (Fugu) genome as a compact model vertebrate genome
1993 StandoutNatureNobel
Inhibition of Silencing and Accelerated Aging by Nicotinamide, a Putative Negative Regulator of Yeast Sir2 and Human SIRT1
2002
The Sirtuins Hst3 and Hst4p Preserve Genome Integrity by Controlling Histone H3 Lysine 56 Deacetylation
2006
Understanding the language of Lys36 methylation at histone H3
2012
Deleted in breast cancer–1 regulates SIRT1 activity and contributes to high-fat diet–induced liver steatosis in mice
2010
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Chromatin Modifications and Their Function
2007 Standout
Sirtuin 1 in lipid metabolism and obesity
2011
The Sir2 family of protein deacetylases
2005
SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin
2008 Nature
A conserved secondary structure for telomerase RNA
1991 StandoutNobel
Oxalyl hydroxamates as reaction-intermediate analogs for ketol-acid reductoisomerase
1990
Splicing regulates NAD metabolite binding to histone macroH2A
2005
Genome-wide patterns of histone modifications in yeast
2006
Histone chaperone ASF1 cooperates with the Brahma chromatin-remodelling machinery
2002
Histone acetyltransferase complexes: one size doesn't fit all
2007
Phylogenetic Classification of Prokaryotic and Eukaryotic Sir2-like Proteins
2000
Proline Isomerization of Histone H3 Regulates Lysine Methylation and Gene Expression
2006
NAD+ as a Signaling Molecule Modulating Metabolism
2011
Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae
2003 Nature
Transcriptional targets of sirtuins in the coordination of mammalian physiology
2008
Mitochondrial longevity pathways
2010
Role of Protein Methylation in Regulation of Transcription
2005
Nucleosome displacement in transcription: Figure 1.
2006
Phosphorylation Regulates SIRT1 Function
2008
Histone deacetylases and cancer: causes and therapies
2001 Standout
Electron Crystal Structure of the Transcription Factor and DNA Repair Complex, Core TFIIH
2000 StandoutNobel
Epigenetics and aging: the targets and the marks
2007
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
2001 StandoutNature
25 years after the nucleosome model: chromatin modifications
2000
Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic β Cells
2005
Identification of Selective Inhibitors of NAD+-dependent Deacetylases Using Phenotypic Screens in Yeast
2003
Therapeutic application of histone deacetylase inhibitors for central nervous system disorders
2008
The Role of Chromatin during Transcription
2007 Standout
Hepatocyte-Specific Deletion of SIRT1 Alters Fatty Acid Metabolism and Results in Hepatic Steatosis and Inflammation
2009
Yeast histone deposition protein Asf1p requires Hir proteins and PCNA for heterochromatic silencing
2001
The Human Sir2 Ortholog, SIRT2, Is an NAD+-Dependent Tubulin Deacetylase
2003
Sir2 and calorie restriction in yeast: A skeptical perspective
2007
Intracellular translation initiation factor levels in Saccharomyces cerevisiae and their role in cap‐complex function
2002
The general transcription factors of RNA polymerase II.
1996
Genes For Tfb2, Tfb3, and Tfb4 Subunits of Yeast Transcription/Repair Factor IIH
1997 StandoutNobel
Telomeric chromatin: replicating and wrapping up chromosome ends
2001
The protein kinases of budding yeast: six score and more
1997
Targeting Sirtuin 1 to Improve Metabolism: All You Need Is NAD+?
2011
The Hallmarks of Aging
2013 Standout
Function and metabolism of sirtuin metabolite O-acetyl-ADP-ribose
2010
Succinate inhibition of α-ketoglutarate-dependent enzymes in a yeast model of paraganglioma
2007
Assembly of the SIR Complex and Its Regulation by O-Acetyl-ADP-Ribose, a Product of NAD-Dependent Histone Deacetylation
2005
SIRT4 Inhibits Glutamate Dehydrogenase and Opposes the Effects of Calorie Restriction in Pancreatic β Cells
2006
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
2007 StandoutNobel
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
2004 StandoutNature
Topological domains in mammalian genomes identified by analysis of chromatin interactions
2012 StandoutNature
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
2003 StandoutNature
Coordination of circadian timing in mammals
2002 StandoutNature
Cut2 proteolysis required for sister-chromatid separation in fission yeast
1996 StandoutNatureNobel
Negative Control of p53 by Sir2α Promotes Cell Survival under Stress
2001 Standout
SIRT1 Regulates HIV Transcription via Tat Deacetylation
2005
SIR2 and aging – the exception that proves the rule
2001
hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase
2001 Standout
RNA polymerase III and RNA polymerase II promoter complexes are heterochromatin barriers in Saccharomyces cerevisiae
2001
Mammalian SIRT1 Represses Forkhead Transcription Factors
2004
The absence of the yeast chromatin assembly factor Asf1 increases genomic instability and sister chromatid exchange
2004
Nuclear Reprogramming in Cells
2008 StandoutScienceNobel
A Physical Map of the Escherichia coli K12 Genome
1987 Science
Functions of the gene products of Escherichia coli
1993
Identification and characterization of a TFIID-like multiprotein complex from Saccharomyces cerevisiae.
1995 StandoutNobel
The Biochemistry of Sirtuins
2006
Controlling histone methylation via trans-histone pathways
2008
Sirtuin 1 and Sirtuin 3: Physiological Modulators of Metabolism
2012
Messenger RNA for myosin polypeptides: Isolation from single myogenic cell cultures
1977
The Protein Kinase Complement of the Human Genome
2002 StandoutScience
Deracemization of α-Aryl Hydrocoumarins via Catalytic Asymmetric Protonation of Ketene Dithioacetals
2012 StandoutNobel
The genome-wide expression response to telomerase deletion in Saccharomyces cerevisiae
2002 StandoutNobel
A vesicle carrier that mediates peroxisome protein traffic from the endoplasmic reticulum
2010 StandoutNobel
The Histone Chaperone Anti-Silencing Function 1 Is a Global Regulator of Transcription Independent of Passage through S Phase
2005
DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism
2003 StandoutScienceNobel
Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
1979 Standout
Dimethylation of Histone H3 at Lysine 36 Demarcates Regulatory and Nonregulatory Chromatin Genome-Wide
2005
Chromatin Modifications by Methylation and Ubiquitination: Implications in the Regulation of Gene Expression
2006
Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling
2011
Two DNA-Binding Factors Recognize Specific Sequences at Silencers, Upstream Activating Sequences, Autonomously Replicating Sequences, and Telomeres in Saccharomyces cerevisiae
1988 StandoutNobel
A quantitative test to estimate neutralizing antibodies to the hepatitis C virus: cytofluorimetric assessment of envelope glycoprotein 2 binding to target cells.
1996 StandoutNobel
General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH
2013 StandoutNobel
The Cln3-Cdc28 kinase complex of S. cerevisiae is regulated by proteolysis and phosphorylation.
1992
Bimolecular Fluorescence Complementation (BiFC) Analysis as a Probe of Protein Interactions in Living Cells
2008
CYCLIN-DEPENDENT KINASES: Engines, Clocks, and Microprocessors
1997 Standout
Activation of yeast RNA polymerase II transcription by a thymidine-rich upstream element in vitro.
1989 StandoutNobel
A single gene from yeast for both nuclear and cytoplasmic polyadenylate-binding proteins: Domain structure and expression
1986 StandoutNobel
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
SIRT2 Suppresses Adipocyte Differentiation by Deacetylating FOXO1 and Enhancing FOXO1's Repressive Interaction with PPARγ
2008
Chromatin remodeling by nucleosome disassembly in vitro
2006 StandoutNobel
The Complete Genome Sequence of Escherichia coli K-12
1997 StandoutScience
Circadian Control of the NAD + Salvage Pathway by CLOCK-SIRT1
2009 Science
SIRT2 regulates NF-κB-dependent gene expression through deacetylation of p65 Lys310
2010
HMG CoA reductase: A negatively regulated gene with unusual promoter and 5′ untranslated regions
1984 StandoutNobel
Identification of a small molecule inhibitor of Sir2p
2001
Disassembly and reconstitution of signal recognition particle
1983 StandoutNobel
Sirtuins — novel therapeutic targets to treat age-associated diseases
2008
Histone3 lysine4 trimethylation regulated by the facilitates chromatin transcription complex is critical for DNA cleavage in class switch recombination
2010 StandoutNobel
Ubp10/Dot4p Regulates the Persistence of Ubiquitinated Histone H2B: Distinct Roles in Telomeric Silencing and General Chromatin
2005
A novel leader peptide which allows efficient secretion of a fragment of human interleukin 1 beta in Saccharomyces cerevisiae.
1987
Functional requirements of AID’s higher order structures and their interaction with RNA-binding proteins
2016 StandoutNobel
Structural analysis of the RSC chromatin-remodeling complex
2002 StandoutNobel
Cap-Independent Translation Is Required for Starvation-Induced Differentiation in Yeast
2007 StandoutScienceNobel
The Secret Life of NAD+: An Old Metabolite Controlling New Metabolic Signaling Pathways
2010
The Sensitivity of Yeast Mutants to Oleic Acid Implicates the Peroxisome and Other Processes in Membrane Function
2006
Thermal chromatography of eukaryotic messenger ribonucleoprotein particles on oligo(dT)‐cellulose
1979
The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease
2006 StandoutScience
In Vivo Protein Transduction: Delivery of a Biologically Active Protein into the Mouse
1999 StandoutScience
A ribonuclease-resistant cytoplasmic 10 S ribonucleoprotein of chick embryonic muscle. A potent inhibitor of cell-free protein synthesis.
1981
Works of Ann Sutton being referenced
SirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosis
2006
The Cdk-Activating Kinase (CAK) from Budding Yeast
1996
Phosphorylation of Cdc28 and regulation of cell size by the protein kinase CKII in Saccharomyces cerevisiae
2000
The yeast SAS (something about silencing) protein complex contains a MYST-type putative acetyltransferase and functions with chromatin assembly factor ASF1
2001
C2H2 zinc finger-SET histone methyltransferase is a plant-specific chromatin modifier
2006
Sas4 and Sas5 Are Required for the Histone Acetyltransferase Activity of Sas2 in the SAS Complex
2003
The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases
2000
The Bur1 Cyclin-Dependent Protein Kinase Is Required for the Normal Pattern of Histone Methylation by Set2
2006
Highly purified mRNA for myosin heavy chain: Size and polyadenylic acid content
1974
Set2-Catalyzed Methylation of Histone H3 Represses Basal Expression of GAL4 in Saccharomyces cerevisiae
2003
Yeast ASF1 Protein Is Required for Cell Cycle Regulation of Histone Gene Transcription
2001
The SIT4 Protein Phosphatase Functions in Late G3 for Progression into S Phase
1991
Cloning and expression of theilvB gene ofEscherichia coli K-12
1982
A Novel Form of Transcriptional Silencing by Sum1-1 Requires Hst1 and the Origin Recognition Complex
2001
Isolation of Messenger Ribonucleic Acid for Myosin Heavy Chain
1973
Signals for Transcription Initiation and Termination in the Saccharomyces cerevisiae Plasmid 2μm Circle
1985