Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
RAS Mutations Contribute to Evolution of Chronic Myelomonocytic Leukemia to the Proliferative Variant
2010
Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders
2009
Defining the human C2H2 zinc finger degrome targeted by thalidomide analogs through CRBN
2018 Science
High-Throughput Characterization of 10 New Minor Histocompatibility Antigens by Whole Genome Association Scanning
2010
A Novel Germline Variant in CSF3R Reduces N-Glycosylation and Exerts Potent Oncogenic Effects in Leukemia
2018 StandoutNobel
Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA
2011 StandoutScience
IDH1 and IDH2 mutation studies in 1473 patients with chronic-, fibrotic- or blast-phase essential thrombocythemia, polycythemia vera or myelofibrosis
2010
Targeted glycan degradation potentiates the anticancer immune response in vivo
2020 StandoutNobel
Programmed cell removal by calreticulin in tissue homeostasis and cancer
2018
Cytogenetic and molecular abnormalities in chronic myelomonocytic leukemia
2016
IDH mutations in primary myelofibrosis predict leukemic transformation and shortened survival: clinical evidence for leukemogenic collaboration with JAK2V617F
2011
SF3B1 deficiency impairs human erythropoiesis via activation of p53 pathway: implications for understanding of ineffective erythropoiesis in MDS
2018
CK1α suppresses lung tumour growth by stabilizing PTEN and inducing autophagy
2018
Increased Thrombopoiesis and Platelet Activation in Hantavirus-Infected Patients
2015 StandoutNobel
HLA Match Likelihoods for Hematopoietic Stem-Cell Grafts in the U.S. Registry
2014 Standout
Functions of DNA methylation: islands, start sites, gene bodies and beyond
2012 Standout
Chronic myeloproliferative diseases with and without the Ph chromosome: some unresolved issues
2009
MYC on the Path to Cancer
2012 Standout
A view on drug resistance in cancer
2019 StandoutNature
CpG islands and the regulation of transcription
2011 Standout
JAK Inhibition with Ruxolitinib versus Best Available Therapy for Myelofibrosis
2012 Standout
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Differential prognostic effect of IDH1 versus IDH2 mutations in myelodysplastic syndromes: a Mayo Clinic Study of 277 patients
2011
Macrophage Activation-Like Syndrome: A Distinct Entity Leading to Early Death in Sepsis
2019
JAKs and STATs in Immunity, Immunodeficiency, and Cancer
2013
Approaches to treat immune hot, altered and cold tumours with combination immunotherapies
2019 Standout
TET Family Proteins and Their Role in Stem Cell Differentiation and Transformation
2011
Metabolic Regulation of Hematopoietic Stem Cells in the Hypoxic Niche
2011 StandoutNobel
Cancer as a dysregulated epigenome allowing cellular growth advantage at the expense of the host
2013
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
Ribosomal Protein Mutations Induce Autophagy through S6 Kinase Inhibition of the Insulin Pathway
2014
Immunogenic cell death in cancer and infectious disease
2016 Standout
Cancer stem cells revisited
2017 Standout
Epigenetics in Cancer: A Hematological Perspective
2016
Rationale for revision and proposed changes of the WHO diagnostic criteria for polycythemia vera, essential thrombocythemia and primary myelofibrosis
2015
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
2010 StandoutNature
DNA methylation: roles in mammalian development
2013 Standout
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes
2015 StandoutNobel
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Advances in DNA methylation: 5-hydroxymethylcytosine revisited
2011
Intratumoral modulation of the inducible co-stimulator ICOS by recombinant oncolytic virus promotes systemic anti-tumour immunity
2017 StandoutNobel
Clonal Hematopoiesis and Evolution to Hematopoietic Malignancies
2018
Factors underlying sensitivity of cancers to small-molecule kinase inhibitors
2009
Macrophages support pathological erythropoiesis in polycythemia vera and β-thalassemia
2013
A Ribosomopathy Reveals Decoding Defective Ribosomes Driving Human Dysmorphism
2017 StandoutNobel
Translation of branched-chain aminotransferase-1 transcripts is impaired in cells haploinsufficient for ribosomal protein genes
2014
Expansion of EPOR-negative macrophages besides erythroblasts by elevated EPOR signaling in erythrocytosis mouse models
2017
Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation
2011
Reduced Mortality after Allogeneic Hematopoietic-Cell Transplantation
2010 Standout
TET enzymes, TDG and the dynamics of DNA demethylation
2013 StandoutNature
Molecular genetics in acute myeloid leukemia
2010
The Behaviour of 5-Hydroxymethylcytosine in Bisulfite Sequencing
2010
Mutations of polycomb‐associated gene ASXL1 in myelodysplastic syndromes and chronic myelomonocytic leukaemia
2009
Clinical Effect of Point Mutations in Myelodysplastic Syndromes
2011 Standout
Chemokines in the cancer microenvironment and their relevance in cancer immunotherapy
2017 Standout
One-Step Generation of Mice Carrying Mutations in Multiple Genes by CRISPR/Cas-Mediated Genome Engineering
2013 Standout
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2
2010 Nature
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
2013 Standout
The cancer stem cell: premises, promises and challenges
2011 Standout
The cancerous translation apparatus
2011
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
COVID-19: consider cytokine storm syndromes and immunosuppression
2020 Standout
Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity
2024 StandoutNobel
Effects ofTET2mutations on DNA methylation in chronic myelomonocytic leukemia
2012
Mitochondrial TCA cycle metabolites control physiology and disease
2020 Standout
Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis
2012
Chronic mast cell leukemia: A novel leukemia-variant with distinct morphological and clinical features
2014
Type I interferons in anticancer immunity
2015
The SF3b complex: splicing and beyond
2020
NF-κB, inflammation, immunity and cancer: coming of age
2018 Standout
The future of epigenetic therapy in solid tumours—lessons from the past
2013
The IUPHAR/BPS Guide to PHARMACOLOGY in 2018: updates and expansion to encompass the new guide to IMMUNOPHARMACOLOGY
2017 Standout
Selective recruitment of stem cell donors with rare human leukocyte antigen phenotypes
2007
Loss of heterozygosity 4q24 and TET2 mutations associated with myelodysplastic/myeloproliferative neoplasms
2009
An Efficient Nonviral Method to Generate Integration-Free Human-Induced Pluripotent Stem Cells from Cord Blood and Peripheral Blood Cells
2012 StandoutNobel
Recent developments in myelodysplastic syndromes
2014
Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice
2011
Acute Myeloid Leukemia
2015 Standout
Identification and transcriptome analysis of erythroblastic island macrophages
2019 StandoutNobel
Peptidic degron for IMiD-induced degradation of heterologous proteins
2019 StandoutNobel
Novel TET2 Mutations Associated With UPD4q24 in Myelodysplastic Syndrome
2009
Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells
2012 StandoutNobel
RUNX1Mutations in Acute Myeloid Leukemia: Results From a Comprehensive Genetic and Clinical Analysis From the AML Study Group
2011
New mutations and pathogenesis of myeloproliferative neoplasms
2011
Diagnosis and management of mastocytosis: an emerging challenge in applied hematology
2015
Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies
2011
Clonal hematopoiesis of indeterminate potential and its distinction from myelodysplastic syndromes
2015 Standout
Liquid Biopsies: Genotyping Circulating Tumor DNA
2014 Standout
Neoantigens in cancer immunotherapy
2015 StandoutScience
Tissue-specific contributions of Tmem79 to atopic dermatitis and mast cell-mediated histaminergic itch
2018 StandoutNobel
TET2 Mutations in Acute Myeloid Leukemia (AML): Results From a Comprehensive Genetic and Clinical Analysis of the AML Study Group
2012
Elevated Levels of Mast Cells Are Involved in Pruritus Associated with Polycythemia Vera in JAK2V617F Transgenic Mice
2014
IDH mutations in Primary Myelofibrosis Predict Leukemic Transformation and Shortened Survival: Clinical Evidence for Leukemogenic Collaboration with JAK2V617F
2011
Mechanisms of Renal Fibrosis
2017 Standout
Lipopolysaccharide binding protein promoter variants influence the risk for Gram-negative bacteremia and mortality after allogeneic hematopoietic cell transplantation
2007
Thrombocytosis: Diagnostic Evaluation, Thrombotic Risk Stratification, and Risk-Based Management Strategies
2011
MicroRNAs, new effectors and regulators of NF‐κB
2012 Nobel
Crbn I391V is sufficient to confer in vivo sensitivity to thalidomide and its derivatives in mice
2018
The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia
2016 Standout
Accurate proteome-wide missense variant effect prediction with AlphaMissense
2023 StandoutScienceNobel
Next-generation sequencing of the TET2 gene in 355 MDS and CMML patients reveals low-abundance mutant clones with early origins, but indicates no definite prognostic value
2010
Works of Ann Mullally being referenced
Depletion of Jak2V617F myeloproliferative neoplasm-propagating stem cells by interferon-α in a murine model of polycythemia vera
2013
Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells
2010
Frequent TET2 mutations in systemic mastocytosis: clinical, KITD816V and FIP1L1-PDGFRA correlates
2009
Loss of Function of TET2 Cooperates with Constitutively Active KIT in Murine and Human Models of Mastocytosis
2014
Physiological Jak2V617F Expression Causes a Lethal Myeloproliferative Neoplasm with Differential Effects on Hematopoietic Stem and Progenitor Cells
2010
Gli1+ Mesenchymal Stromal Cells Are a Key Driver of Bone Marrow Fibrosis and an Important Cellular Therapeutic Target
2017
A germline JAK2 SNP is associated with predisposition to the development of JAK2V617F-positive myeloproliferative neoplasms
2009
TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis
2009
Physiologic Expression of Sf3b1 K700E Causes Impaired Erythropoiesis, Aberrant Splicing, and Sensitivity to Therapeutic Spliceosome Modulation
2016
Role of Casein Kinase 1A1 in the Biology and Targeted Therapy of del(5q) MDS
2014
Defining the requirements for the pathogenic interaction between mutant calreticulin and MPL in MPN
2017
Beyond HLA: the significance of genomic variation for allogeneic hematopoietic stem cell transplantation
2006
Haemophagocytic lymphohistiocytosis in adults: a multicentre case series over 7 years
2015
Coordinate loss of a microRNA and protein-coding gene cooperate in the pathogenesis of 5q− syndrome
2011
Distinct effects of concomitant Jak2V617F expression and Tet2 loss in mice promote disease progression in myeloproliferative neoplasms
2014