Standout Papers
Citation Impact
Citing Papers
The mir-84 and let-7 paralogous microRNA genes of Caenorhabditis elegans direct the cessation of molting via the conserved nuclear hormone receptors NHR-23 and NHR-25
2006 StandoutNobel
The C. elegans heterochronic gene lin-28 coordinates the timing of hypodermal and somatic gonadal programs for hermaphrodite reproductive system morphogenesis
2019 StandoutNobel
Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution
2009 StandoutScienceNobel
Conformational Switch of Syntaxin-1 Controls Synaptic Vesicle Fusion
2008 StandoutScienceNobel
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
Identification of a Decay in Transcription Potential That Results in Elongation Factor Dependence of RNA Polymerase II
1995
Sterol effects and sites of sterol accumulation in Caenorhabditis elegans
2003
The hedgehog‐related gene qua‐1 is required for molting in Caenorhabditis elegans
2006
Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis
2006 StandoutNobel
SEC14L2 enables pan-genotype HCV replication in cell culture
2015 StandoutNatureNobel
MicroRNAs
2004 Standout
DAF-9, a cytochrome P450 regulatingC. eleganslarval development and adult longevity
2002
Elongator, a Multisubunit Component of a Novel RNA Polymerase II Holoenzyme for Transcriptional Elongation
1999
High-Throughput Isolation of Caenorhabditis elegans Deletion Mutants
1999
Characterization of Elongin C Functional Domains Required for Interaction with Elongin B and Activation of Elongin A
1996
Why do worms need cholesterol?
2003
Initiation of transcription by RNA polymerase II
1989
RSC, an Essential, Abundant Chromatin-Remodeling Complex
1996 StandoutNobel
Genetic Regulation of Unsaturated Fatty Acid Composition in C. elegans
2006
An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming
2001 Nature
The conserved nuclear receptor Ftz‐F1 is required for embryogenesis, moulting and reproduction in Caenorhabditis elegans
2000
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses
2012 StandoutNobel
The Expression of the let-7 Small Regulatory RNA Is Controlled by Ecdysone during Metamorphosis in Drosophila melanogaster
2002 StandoutNobel
A microRNA program in the C. elegans hypodermis couples to intestinal mTORC2/PQM-1 signaling to modulate fat transport
2016 StandoutNobel
The sterol modifying enzyme LET-767 is essential for growth, reproduction and development in Caenorhabditis elegans
2003
The C. elegans intestine
2007
Contacts between mammalian RNA polymerase II and the template DNA in a ternary elongation complex
1993
Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK
1994 StandoutNobel
A mediator required for activation of RNA polymerase II transcription in vitro
1991 StandoutNatureNobel
Formation and Crystallization of Yeast RNA Polymerase II Elongation Complexes
1997 StandoutNobel
Steroid hormone receptors: Evolution, ligands, and molecular basis of biologic function
1999
Stimulation of transcript elongation requires both the zinc finger and RNA polymerase II binding domains of human TFIIS
1991
Human Transcription Release Factor 2 Dissociates RNA Polymerases I and II Stalled at a Cyclobutane Thymine Dimer
1999 StandoutNobel
Promoting elongation with transcript cleavage stimulatory factors
2002
Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7
2008 StandoutNatureNobel
Genes and Mechanisms Related to RNA Interference Regulate Expression of the Small Temporal RNAs that Control C. elegans Developmental Timing
2001 StandoutNobel
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
2003 StandoutNatureNobel
β Phorbol Ester- and Diacylglycerol-Induced Augmentation of Transmitter Release Is Mediated by Munc13s and Not by PKCs
2002 StandoutNobel
Comparing nuclear receptors in worms, flies and humans
2001
Suppression of inflammation by a synthetic histone mimic
2010 StandoutNatureNobel
Analysis of the gene encoding the largest subunit of RNA polymerase II in Drosophila
1989
General Transcription Factors for RNA Polymerase II1
1997
Architecture of the RNA polymerase II–TFIIF complex revealed by cross-linking and mass spectrometry
2010
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Functional Genomic Analysis of C. elegans Molting
2005 StandoutNobel
Identification of the Region in Yeast S-II That Defines Species Specificity in Its Interaction with RNA Polymerase II
1997
The nuclear hormone receptor NHR-86 controls anti-pathogen responses in C. elegans
2019
A multiprotein mediator of transcriptional activation and its interaction with the C-terminal repeat domain of RNA polymerase II
1994 StandoutNobel
Control of RNA Polymerase II Elongation Potential by a Novel Carboxyl-terminal Domain Kinase
1996
The HCV Life Cycle: In vitro Tissue Culture Systems and Therapeutic Targets
2014 Standout
Elongation by RNA polymerase II: the short and long of it
2004
Understanding the hepatitis C virus life cycle paves the way for highly effective therapies
2013 StandoutNobel
Elongation Factor SII Contacts the 3′-End of RNA in the RNA Polymerase II Elongation Complex
1996
An RNA polymerase II holoenzyme responsive to activators
1994 Nature
Transcript cleavage factors from E. coli
1993
How many nuclear hormone receptors are there in the human genome?
2001
The time of appearance of the C. elegans let-7 microRNA is transcriptionally controlled utilizing a temporal regulatory element in its promoter
2003
A novel mediator between activator proteins and the RNA polymerase II transcription apparatus
1990 StandoutNobel
Selective Activation of Cognate SNAREpins by Sec1/Munc18 Proteins
2007 StandoutNobel
Hypermutability and mismatch repair deficiency in RER+ tumor cells
1993 StandoutNobel
Functional modularity of nuclear hormone receptors in a Caenorhabditis elegans metabolic gene regulatory network
2010
Architecture of an RNA Polymerase II Transcription Pre-Initiation Complex
2013 StandoutScienceNobel
RNA polymerase II transcription factor SIII. II. Functional properties and role in RNA chain elongation.
1993
Identification of Farnesoid X Receptor β as a Novel Mammalian Nuclear Receptor Sensing Lanosterol
2003 StandoutNobel
Orphan Nuclear Receptors: From Gene to Function*
1999
Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells
1995 StandoutScienceNobel
Nuclear Receptors and Lipid Physiology: Opening the X-Files
2001 StandoutScience
Initiation of eukaryotic messenger RNA synthesis.
1991
An RNA polymerase II transcription factor has an associated DNA-dependent ATPase (dATPase) activity strongly stimulated by the TATA region of promoters.
1989
Binding of the von Hippel-Lindau Tumor Suppressor Protein to Elongin B and C
1995 StandoutScienceNobel
RNA Polymerase II Initiation Factor Interactions and Transcription Start Site Selection
1994 StandoutScienceNobel
Analysis of Homologous Gene Clusters inCaenorhabditis elegansReveals Striking Regional Cluster Domains
2005
Elongin (SIII): A Multisubunit Regulator of Elongation by RNA Polymerase II
1995 Science
Structural Basis of Transcription: Separation of RNA from DNA by RNA Polymerase II
2004 StandoutScienceNobel
MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans
2000 StandoutNatureNobel
Resolution of factors required for the initiation of transcription by yeast RNA polymerase II.
1990 StandoutNobel
Structural Basis of Transcription: An RNA Polymerase II Elongation Complex at 3.3 Å Resolution
2001 StandoutScienceNobel
Fractionation of the general RNA polymerase II transcription factors from Drosophila embryos.
1990
GERp95, a Membrane-associated Protein that Belongs to a Family of Proteins Involved in Stem Cell Differentiation
1999
BASIC MECHANISMS OF TRANSCRIPT ELONGATION AND ITS REGULATION
1997
Transcription initiated by RNA polymerase II and purified transcription factors from liver. Cooperative action of transcription factors tau and epsilon in initial complex formation.
1990
Regulation of ectodermal and excretory function by the C. elegans POU homeobox gene ceh-6
2001 StandoutNobel
A multisubunit transcription factor essential for accurate initiation by RNA polymerase II
1989
Molecular Matchmakers
1993 StandoutScienceNobel
RNA Polymerase II Elongation Complexes Paused after the Synthesis of 15- or 35-Base Transcripts Have Different Structures
1991
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
The Taxonomy of Developmental Control in Caenorhabditis elegans
1998 StandoutScienceNobel
The RNA polymerase II ternary complex cleaves the nascent transcript in a 3'----5' direction in the presence of elongation factor SII.
1992
Transcript cleavage by RNA polymerase II arrested by a cyclobutane pyrimidine dimer in the DNA template.
1994
The RNA Polymerase II Elongation Complex
2003
In vitro characterization of mutant yeast RNA polymerase II with reduced binding for elongation factor TFIIS.
1996
Rapid and Precise Engineering of theCaenorhabditis elegansGenome with Lethal Mutation Co-Conversion and Inactivation of NHEJ Repair
2014
A protein kinase that phosphorylates the C-terminal repeat domain of the largest subunit of RNA polymerase II.
1989
Cloning of a Subunit of Yeast RNA Oolymerase II Transcription Factor b and CTD Kinase
1992 StandoutScienceNobel
Structure of the VHL-ElonginC-ElonginB Complex: Implications for VHL Tumor Suppressor Function
1999 StandoutScienceNobel
Genetic Interaction between Transcription Elongation Factor TFIIS and RNA Polymerase II
1992
Positive regulation of general transcription factor SIII by a tailed ubiquitin homolog.
1995
Molecular cloning of an essential subunit of RNA polymerase II elongation factor SIII.
1994
The Caenorhabditis elegans Nuclear Receptor Gene nhr-25 Regulates Epidermal Cell Development
2004
Strand-specific mismatch correction in nuclear extracts of human and Drosophila melanogaster cell lines.
1990 StandoutNobel
Architecture of RNA Polymerase II and Implications for the Transcription Mechanism
2000 StandoutScienceNobel
Analysis of xbx genes in C. elegans
2005 StandoutNobel
Transcription Elongation Factor SII (TFIIS) Enables RNA Polymerase II to Elongate through a Block to Transcription in a Human Gene in Vitro
1989
Factors regulating the transcriptional elongation activity of RNA polymerase II
1998
The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins
2004 StandoutNobel
Nuclear hormone receptor CHR3 is a critical regulator of all four larval molts of the nematodeCaenorhabditis elegans
2001
Structural Basis of Transcription: An RNA Polymerase II-TFIIB Cocrystal at 4.5 Angstroms
2004 StandoutScienceNobel
Nascent RNA cleavage by arrested RNA polymerase II does not require upstream translocation of the elongation complex on DNA.
1993
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
Multiple sets of basal factors initiate transcription by RNA polymerase II
1994
GreA protein: a transcription elongation factor from Escherichia coli.
1992
Mismatch Repair, Genetic Stability, and Cancer
1994 StandoutScienceNobel
Topology of Yeast RNA Polymerase II Subunits in Transcription Elongation Complexes Studied by Photoaffinity Cross-Linking
2000
Reconstitution of transcription with five purified initiation factors and RNA polymerase II from Saccharomyces cerevisiae
1992 StandoutNobel
CHR3: a Caenorhabditis elegans orphan nuclear hormone receptor required for proper epidermal development and molting
1998
Elongation factor-dependent transcript shortening by template-engaged RNA polymerase II.
1992
Works of Ann E. Sluder being referenced
Explosive Lineage-Specific Expansion of the Orphan Nuclear Receptor HNF4 in Nematodes
2005
The Caenorhabditis elegans NR4A nuclear receptor is required for spermatheca morphogenesis
2007
A C. elegans orphan nuclear receptor contributes to xenobiotic resistance
2001
HCV NS5A and IRF9 compete for CypA binding
2012
nhr-25, the Caenorhabditis elegans Ortholog of ftz-f1, Is Required for Epidermal and Somatic Gonad Development
2000
Expression and Function of Members of a Divergent Nuclear Receptor Family in Caenorhabditis elegans
1999
Expression and function of conserved nuclear receptor genes in Caenorhabditis elegans
2003
Comparison of complete nuclear receptor sets from the human, Caenorhabditis elegans and Drosophila genomes
2001
Nuclear receptors in nematodes: themes and variations
2001
The cyclophilin inhibitor SCY-635 suppresses viral replication and induces endogenous interferons in patients with chronic HCV genotype 1 infection
2012
TheCaenorhabditis elegansOrphan Nuclear Hormone Receptor Genenhr-2Functions in Early Embryonic Development
1997 StandoutNobel
Dynamic Interaction between a Drosophila Transcription Factor and RNA Polymerase II
1989
Elongation by Drosophila RNA polymerase II. Transcription of 3′-extended DNA templates.
1988
10 CYCLOPHILIN INHIBITORS POTENTIATE INTERFERON SIGNALING THROUGH DIMINISHED PKR PHOSPHORYLATION IN HCV-INFECTED CELLS
2013
Properties of a Drosophila RNA Polymerase II Elongation Factor
1989
Therapeutic target discovery using Caenorhabditis elegans
2000
Fractionation of transcription factors for RNA polymerase II from Drosophila Kc cell nuclear extracts.
1987
RNAi-based discovery and validation of new drug targets in filarial nematodes
2004
The Nuclear Receptor Superfamily Has Undergone Extensive Proliferation and Diversification in Nematodes
1999
Dynamic interaction between a Drosophila transcription factor and RNA polymerase II.
1989