Angelo Toto

Sculpting conducting nanopore size and shape through de novo protein design

The Stability Landscape of de novo TIM Barrels Explored by a Modular Design Approach

Insights into Coupled Folding and Binding Mechanisms from Kinetic Studies

The role of interleukin-1 in the pathogenesis of IDDM

Transgenic overexpression of human Bcl-2 in islet β cells inhibits apoptosis but does not prevent autoimmune destruction

Interleukin‐6 an endocrine cytokine

Helical Propensity in an Intrinsically Disordered Protein Accelerates Ligand Binding

Double-mutant cycles: new directions and applications

Islet expression of interferon-α precedes diabetes in both the BB rat and streptozotocin-treated mice

Intrinsically disordered proteins in cellular signalling and regulation

Subcutaneous Adipose Tissue Releases Interleukin-6, But Not Tumor Necrosis Factor-α,in Vivo¹

Design of amyloidogenic peptide traps

The binding mechanisms of intrinsically disordered proteins

Adipose Tissue as an Endocrine Organ

Frustration Sculpts the Early Stages of Protein Folding

Allostery within a transcription coactivator is predominantly mediated through dissociation rate constants

Physicochemical Properties of Cells and Their Effects on Intrinsically Disordered Proteins (IDPs)

Sequence–Structure–Binding Relationships Reveal Adhesion Behavior of the Car9 Solid-Binding Peptide: An Integrated Experimental and Simulation Study

Nanomaterials and nanoparticles: Sources and toxicity

Introducing Protein Intrinsic Disorder

TYPE I INTERFERONS (α/β) IN IMMUNITY AND AUTOIMMUNITY

Natural and Designed Proteins Inspired by Extremotolerant Organisms Can Form Condensates and Attenuate Apoptosis in Human Cells

Classification of Intrinsically Disordered Regions and Proteins

Is Juvenile Diabetes a Viral Disease?

Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system

Understanding the effect of alternative splicing in the folding and function of the second PDZ from Protein Tyrosine Phosphatase-BL

The Folding Pathway of the KIX Domain

The mechanism of binding of the KIX domain to the mixed lineage leukemia protein and its allosteric role in the recognition of c‐Myb

Viral infection induces cytokine release by beta islet cells.