Standout Papers
Citation Impact
Citing Papers
Tumor Vaccines Expressing Flt3 Ligand Synergize with CTLA-4 Blockade to Reject Preimplanted Tumors
2009 StandoutNobel
The 2016 revision of the World Health Organization classification of lymphoid neoplasms
2016 Standout
IL-5 Is Required for Eosinophil Recruitment, Crystal Deposition, and Mononuclear Cell Recruitment During a Pulmonary Cryptococcus neoformans Infection in Genetically Susceptible Mice (C57BL/6)
1998
Bacterial DNA Containing CpG Motifs Stimulates Lymphocyte-Dependent Protection of Mice Against Lethal Infection with Intracellular Bacteria
1999
IL-13 Induces Disease-Promoting Type 2 Cytokines, Alternatively Activated Macrophages and Allergic Inflammation during Pulmonary Infection of Mice with Cryptococcus neoformans
2007
The success and failure of BCG — implications for a novel tuberculosis vaccine
2005
Tuberculosis Associated with Infliximab, a Tumor Necrosis Factor α–Neutralizing Agent
2001 Standout
Ischemia and reperfusion—from mechanism to translation
2011 Standout
Pilon: An Integrated Tool for Comprehensive Microbial Variant Detection and Genome Assembly Improvement
2014 Standout
Comparative Analysis of Mycobacterium tuberculosis pe and ppe Genes Reveals High Sequence Variation and an Apparent Absence of Selective Constraints
2012
Relating TCR-peptide-MHC affinity to immunogenicity for the design of tumor vaccines
2006
Applications of nanotechnology for immunology
2013
Antigen-Specific CD8+ T Cells and Protective Immunity to Tuberculosis
2013
Perspectives series: host/pathogen interactions. Mechanisms of nitric oxide-related antimicrobial activity.
1997 Standout
Inducible nitric oxide synthase: what difference does it make?
1997
mRNA vaccines — a new era in vaccinology
2018 StandoutNobel
Cancer nanomedicine: progress, challenges and opportunities
2016 Standout
Elevated Pre–Antiretroviral Therapy CD39+CD8+ T Cell Frequency Is Associated With Early Mortality in Advanced Human Immunodeficiency Virus/Tuberculosis Co-infection
2017 StandoutNobel
mRNA-based cancer vaccine: prevention of B16 melanoma progression and metastasis by systemic injection of MART1 mRNA histidylated lipopolyplexes
2007
Liposome–nucleic acid immunotherapeutics
2007
Efficacy and safety of ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with psoriasis: 76-week results from a randomised, double-blind, placebo-controlled trial (PHOENIX 1)
2008 Standout
Leukocyte recruitment during pulmonary Cryptococcus neoformans infection
2000
Nodular Lymphocyte Predominant Hodgkin Lymphoma and T Cell/Histiocyte Rich Large B Cell Lymphoma - Endpoints of a Spectrum of One Disease?
2013
Granulocyte-macrophage colony-stimulating factor (GM-CSF) and T-cell responses: what we do and don't know
2006
Crohn's disease
2012 Standout
The Genome of Mycobacterium Africanum West African 2 Reveals a Lineage-Specific Locus and Genome Erosion Common to the M. tuberculosis Complex
2012
Immunological profiling of tuberculosis-associated immune reconstitution inflammatory syndrome and non-immune reconstitution inflammatory syndrome death in HIV-infected adults with pulmonary tuberculosis starting antiretroviral therapy: a prospective observational cohort study
2015 StandoutNobel
New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer
2018 Standout
Selenium and human health
2012 Standout
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
The RNA Sensor RIG-I Dually Functions as an Innate Sensor and Direct Antiviral Factor for Hepatitis B Virus
2014 StandoutNobel
PI3K signaling of autophagy is required for starvation tolerance and virulenceof Cryptococcus neoformans
2008 StandoutNobel
Mycobacteria release active membrane vesicles that modulate immune responses in a TLR2-dependent manner in mice
2011
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
Robust Reconstitution of Tuberculosis-Specific Polyfunctional CD4+T-Cell Responses and Rising Systemic Interleukin 6 in Paradoxical Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome
2015 StandoutNobel
Does M. tuberculosis genomic diversity explain disease diversity?
2010
Identification of Two Distinct Macrophage Subsets with Divergent Effects Causing either Neurotoxicity or Regeneration in the Injured Mouse Spinal Cord
2009 Standout
M. tuberculosis and M. leprae Translocate from the Phagolysosome to the Cytosol in Myeloid Cells
2007 Standout
Living in the liver: hepatic infections
2012
Tuberculosis control and elimination 2010–50: cure, care, and social development
2010 Standout
Dietary Selenium Modulates Activation and Differentiation of CD4+ T Cells in Mice through a Mechanism Involving Cellular Free Thiols
2010
Tuberculosis
2007
Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists
2007
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
1999 Standout
Alternative Activation of Macrophages: Mechanism and Functions
2010 Standout
Interleukin-23 Promotes a Distinct CD4 T Cell Activation State Characterized by the Production of Interleukin-17
2003 Standout
Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major
2007 Standout
Macrophage plasticity and polarization: in vivo veritas
2012 Standout
A Riboswitch-Based Inducible Gene Expression System for Mycobacteria
2012 StandoutNobel
Animal Models of Tuberculosis: Guinea Pigs
2014
Autophagy Is a Defense Mechanism Inhibiting BCG and Mycobacterium tuberculosis Survival in Infected Macrophages
2004 Standout
Interleukin-12, interleukin-23, and psoriasis: Current prospects
2007
Tackling the cancer stem cells — what challenges do they pose?
2014
Points of control in inflammation
2002 StandoutNature
Alternative activation deprives macrophages of a coordinated defense program to Mycobacterium tuberculosis
2006
Umbilical Arterial S-nitrosothiols in Stressed Newborns: Role in Perinatal Circulatory Transition
1998 StandoutNobel
Cornerstones of CRISPR–Cas in drug discovery and therapy
2016 StandoutNobel
Tuberculosis vaccine development: goals, immunological design, and evaluation
2008
Molecular and cellular insights into T cell exhaustion
2015 Standout
Pyrazinamide clearance is impaired among HIV/tuberculosis patients with high levels of systemic immune activation
2017 StandoutNobel
Exploring the full spectrum of macrophage activation
2008 Standout
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease
2015 Standout
Pathogen-associated molecular patterns on biomaterials: a paradigm for engineering new vaccines
2011
Alternative activation of macrophages
2003 Standout
Phosphodiesterase-4 Inhibition Combined with Isoniazid Treatment of Rabbits with Pulmonary Tuberculosis Reduces Macrophage Activation and Lung Pathology
2011
Matrix metalloproteinase inhibitors enhance the efficacy of frontline drugs against Mycobacterium tuberculosis
2018
Conserved Immune Recognition Hierarchy of Mycobacterial PE/PPE Proteins during Infection in Natural Hosts
2012
Mycobacterium tuberculosis CDC1551 Induces a More Vigorous Host Response In Vivo and In Vitro, But Is Not More Virulent Than Other Clinical Isolates
1999
Sulfatase-activated fluorophores for rapid discrimination of mycobacterial species and strains
2013 StandoutNobel
Toll-Like Receptors
2003 Standout
Sequestration From Immune CD4 + T Cells of Mycobacteria Growing in Human Macrophages
1993 StandoutScienceNobel
Identification of nitric oxide synthase as a protective locus against tuberculosis
1997
Inhibition of Ca2+ Signaling by Mycobacterium tuberculosisIs Associated with Reduced Phagosome–Lysosome Fusion and Increased Survival within Human Macrophages
2000
Lung Injury on Antiretroviral Therapy in Adults With Human Immunodeficiency Virus/Tuberculosis
2019 StandoutNobel
Construction and Phenotypic Characterization of an Auxotrophic Mutant of Mycobacterium tuberculosis Defective in l -Arginine Biosynthesis
2002
Apoptosis, but not necrosis, of infected monocytes is coupled with killing of intracellular bacillus Calmette-Guérin.
1994
Liposome-Based Adjuvants for Subunit Vaccines: Formulation Strategies for Subunit Antigens and Immunostimulators
2016
Induction of Interleukin-12 and Gamma Interferon Requires Tumor Necrosis Factor Alpha for Protective T1-Cell-Mediated Immunity to PulmonaryCryptococcus neoformansInfection
2002
Strength of TCR–Peptide/MHC Interactions and In Vivo T Cell Responses
2011 StandoutNobel
Control of Chronic Mycobacterium tuberculosis Infection by CD4 KLRG1− IL-2–Secreting Central Memory Cells
2013
Sprouty-2 regulates HIV-specific T cell polyfunctionality
2013
CCR2 Expression Determines T1 Versus T2 Polarization During Pulmonary Cryptococcus neoformans Infection
2000
Sensing of Viral Infection and Activation of Innate Immunity by Toll-Like Receptor 3
2008
Differential Regulation of Immune Responses by Highly and Weakly VirulentCryptococcus neoformansIsolates
1999
Interleukin-12 Is Essential for a Protective Th1 Response in Mice Infected withCryptococcus neoformans
1998
MmpL8 is required for sulfolipid-1 biosynthesis and Mycobacterium tuberculosis virulence
2003 StandoutNobel
Exosomes carrying mycobacterial antigens can protect mice against M ycobacterium tuberculosis infection
2013
Nonreplicating Persistence ofMycobacteriumTuberculosis
2001
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Interleukin-10 and the Interleukin-10 Receptor
2001 Standout
Declines in Lung Function After Antiretroviral Therapy Initiation in Adults With Human Immunodeficiency Virus and Tuberculosis: A Potential Manifestation of Respiratory Immune Reconstitution Inflammatory Syndrome
2019 StandoutNobel
Genetic requirements for mycobacterial survival during infection
2003 Standout
Characterization of Auxotrophic Mutants of Mycobacterium tuberculosis and Their Potential as Vaccine Candidates
2001
Cytokine Profiles of AIDS Patients Are Similar to Those of Mice with DisseminatedCryptococcus neoformansInfection
1999
Mechanism of Oxidation Reactions Catalyzed by Cytochrome P450 Enzymes
2004 Standout
Infection by Mycobacterium tuberculosis promotes human alveolar macrophage apoptosis
1997
N‐Carboxyanhydride Polymerization of Glycopolypeptides That Activate Antigen‐Presenting Cells through Dectin‐1 and Dectin‐2
2018 StandoutNobel
The Continuing Challenges of Leprosy
2006 Standout
Works of Angelo Izzo being referenced
Preclinical evidence for implementing a prime-boost vaccine strategy for tuberculosis
2012
Protection and Polyfunctional T Cells Induced by Ag85B-TB10.4/IC31® against Mycobacterium tuberculosis Is Highly Dependent on the Antigen Dose
2009
Portrait of a Pathogen: The Mycobacterium tuberculosis Proteome In Vivo
2010
BAT3 Regulates Mycobacterium tuberculosis Protein ESAT-6-Mediated Apoptosis of Macrophages
2012
Assessment of vaccine testing at three laboratories using the guinea pig model of tuberculosis
2011
A matrix metalloproteinase inhibitor promotes granuloma formation during the early phase of Mycobacterium tuberculosis pulmonary infection
2004
A multistage tuberculosis vaccine that confers efficient protection before and after exposure
2011
IL-12 and IFN- γ Are Required for Initiating the Protective Th1 Response to Pulmonary Cryptococcosis in Resistant C.B-17 Mice
1997 Standout
Role for Matrix Metalloproteinase 9 in Granuloma Formation during PulmonaryMycobacterium tuberculosisInfection
2006
Disruption of granulocyte macrophage-colony stimulating factor production in the lungs severely affects the ability of mice to controlMycobacterium tuberculosisinfection
2005
Tracking Antigen-Specific CD8 T Lymphocytes in the Lungs of Mice Vaccinated with the Mtb72F Polyprotein
2005
Mycobacterial virulence. Virulent strains of Mycobacteria tuberculosis have faster in vivo doubling times and are better equipped to resist growth-inhibiting functions of macrophages in the presence and absence of specific immunity.
1993
Memory T Lymphocytes Generated byMycobacterium bovisBCG Vaccination Reside within a CD4 CD44loCD62 LigandhiPopulation
2005
Mycobacterium bovis BCG Vaccine Strains Lack narK2 and narX Induction and Exhibit Altered Phenotypes during Dormancy
2008
Deciphering the proteome of the in vivo diagnostic reagent “purified protein derivative” from M ycobacterium tuberculosis
2012
The Protective Effect of the Mycobacterium bovis BCG Vaccine Is Increased by Coadministration with the Mycobacterium tuberculosis 72-Kilodalton Fusion Polyprotein Mtb72F in M. tuberculosis -Infected Guinea Pigs
2004
Evidence for an alpha/beta T cell-independent mechanism of resistance to mycobacteria. Bacillus-Calmette-Guerin causes progressive infection in severe combined immunodeficient mice, but not in nude mice or in mice depleted of CD4+ and CD8+ T cells.
1992
Kinetics of the Immune Response Profile in Guinea Pigs after Vaccination withMycobacterium bovisBCG and Infection withMycobacterium tuberculosis
2009
Efficient Immunization and Cross-Priming by Vaccine Adjuvants Containing TLR3 or TLR9 Agonists Complexed to Cationic Liposomes
2006
Identification of Novel Resident Pulmonary Stem Cells: Form and Function of the Lung Side Population
2005