Citation Impact
Citing Papers
Cleavage of 5′ splice site and lariat formation are independent of 3′ splice site in yeast mRNA splicing
1985 StandoutNatureNobel
Identification of a novel nuclear pore-associated protein as a functional target of the HIV-1 Rev protein in yeast
1995 StandoutNobel
In vitrosplicing of mRNA precursors: 5' cleavage site can be predicted from the interaction between the 5' splice region and the 5' terminus of U1 snRNA
1988
A Putative Mammalian RNA Helicase with an Arginine-Serine-rich Domain Colocalizes with a Splicing Factor
1995 StandoutNobel
Involvement of U1 Small Nuclear Ribonucleoproteins (snRNP) in 5′ Splice Site-U1 snRNP Interaction
1996
Defining a 5??? splice site by functional selection in the presence and absence of U1 snRNA 5??? end
2002
Evidence for an essential non-Watson–Crick interaction between the first and last nucleotides of a nuclear pre-mRNA intron
1993 Nature
A rab protein is required for the assembly of SNARE complexes in the docking of transport vesicles
1994 StandoutNobel
A novel base-pairing interaction between U2 and U6 snRNAs suggests a mechanism for the catalytic activation of the spliceosome
1992
Requirements for U2 snRNP addition to yeast pre-mRNA
1992 StandoutNobel
U1 snRNP-ASF/SF2 interaction and 5′ splice site recognition: characterization of required elements
1995
Membrane fusion and the cell cycle: Cdc48p participates in the fusion of ER membranes
1995 StandoutNobel
The U1 snRNP protein U1C recognizes the 5′ splice site in the absence of base pairing
2002 StandoutNatureNobel
The telomere terminal transferase of tetrahymena is a ribonucleoprotein enzyme with two kinds of primer specificity
1987 StandoutNobel
Mutations in yeast U5 snRNA alter the specificity of 5′ splice-site cleavage
1991
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
1993 StandoutNobel
MEX-3 Is a KH Domain Protein That Regulates Blastomere Identity in Early C. elegans Embryos
1996 StandoutNobel
The involvement of RNA in ribosome function
2002 StandoutNatureNobel
Biochemical Mechanisms of Constitutive and Regulated Pre-mRNA Splicing
1991
Exon mutations uncouple 5′ splice site selection from U1 snRNA pairing
1990 StandoutNobel
SNAP receptors implicated in vesicle targeting and fusion
1993 StandoutNatureNobel
The Splicing Factor BBP Interacts Specifically with the Pre-mRNA Branchpoint Sequence UACUAAC
1997 StandoutNobel
SR proteins can compensate for the loss of U1 snRNP functions in vitro.
1994
Identification of functional U1 snRNA-pre-mRNA complexes committed to spliceosome assembly and splicing
1989 StandoutNobel
Splicing and spliceosome formation of the yeastMATa1transcript require a minimum distance from the 5' splice site to the internal branch acceptor site
1988
Base-Pairing between 23S rRNA and tRNA in the Ribosomal A Site
1999
Operons in C. elegans: Polycistronic mRNA precursors are processed by trans-splicing of SL2 to downstream coding regions
1993
The role of U5 snRNP in pre-mRNA splicing
1997
A DNA metalloenzyme with DNA ligase activity
1995 StandoutNatureNobel
Cotranscriptional Spliceosome Assembly Dynamics and the Role of U1 snRNA:5′ss Base Pairing in Yeast
2005 StandoutNobel
Splicing-related catalysis by protein-free snRNAs
2001 Nature
Cross-Intron Bridging Interactions in the Yeast Commitment Complex Are Conserved in Mammals
1997 StandoutNobel
Functional Recognition of the 5′ Splice Site by U4/U6.U5 tri-snRNP Defines a Novel ATP-Dependent Step in Early Spliceosome Assembly
2000
Characterization of U4 and U6 interactions with the 5′ splice site using a S. cerevisiae in vitro trans-splicing system
2001
Disruption of base pairing between the 5′ splice site and the 5′ end of U1 snRNA is required for spliceosome assembly
1993
Control of branch-site choice by a group II intron
2001
Mutations in U1 snRNA bypass the requirement for a cell type-specific RNA splicing factor
1993
The chemical repertoire of natural ribozymes
2002 StandoutNatureNobel
Nuclear pre‐mRNA splicing in yeast
1989
Regulation by HIV Rev depends upon recognition of splice sites
1989 StandoutNobel
lin-35 and lin-53, Two Genes that Antagonize a C. elegans Ras Pathway, Encode Proteins Similar to Rb and Its Binding Protein RbAp48
1998 StandoutNobel
Mutational analysis of pre-mRNA splicing in Saccharomyces cerevisiae using a sensitive new reporter gene, CUP1.
1993
C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2
1994 StandoutNobel
Mechanisms of intracellular protein transport
1994 StandoutNatureNobel
Control of cell fates in the central body region of C. elegans by the homeobox gene lin-39
1993 StandoutNobel
Sequence requirements for splicing of higher eukaryotic nuclear pre-mRNA
1986
Four yeast spliceosomal proteins (PRP5, PRP9, PRP11, and PRP21) interact to promote U2 snRNP binding to pre-mRNA.
1993
PRP4: a Protein of the Yeast U4/U6 Small Nuclear Ribonucleoprotein Particle
1989
Splicing in Caenorhabditis elegans does not require an AG at the 3' splice acceptor site.
1993
The yeast PRP6 gene encodes a U4/U6 small nuclear ribonucleoprotein particle (snRNP) protein, and the PRP9 gene encodes a protein required for U2 snRNP binding.
1990 StandoutNobel
U2 RNA from yeast is unexpectedly large and contains homology to vertebrate U4, U5, and U6 small nuclear RNAs
1986
PRE-mRNA SPLICING
1986
A general two-metal-ion mechanism for catalytic RNA.
1993 StandoutNobel
Activation of a cryptic TACTAAC box in the Saccharomyces cerevisiae actin intron.
1986
Differential nuclease sensitivity identifies tight contacts between yeast pre-mRNA and spliceosomes.
1986 StandoutNobel
Mutations in U6 snRNA that Alter Splice Site Specificity: Implications for the Active Site
1993 Science
The role of small nuclear ribonucleoprotein particles in pre-mRNA splicing
1987 Nature
Mutations in a yeast intron demonstrate the importance of specific conserved nucleotides for the two stages of nuclear mRNA splicing
1986
Early Commitment of Yeast Pre-mRNA to the Spliceosome Pathway
1988 StandoutNobel
A U1/U4/U5 snRNP Complex Induced by a 2′- O -Methyl-Oligoribonucleotide Complementary to U5 snRNA
1996 Science
The yeast MUD2 protein: an interaction with PRP11 defines a bridge between commitment complexes and U2 snRNP addition.
1994 StandoutNobel
The Branchpoint Residue Is Recognized during Commitment Complex Formation before Being Bulged out of the U2 snRNA–pre-mRNA Duplex
1997
Mutations in conserved intron sequences affect multiple steps in the yeast splicing pathway, particularly assembly of the spliceosome.
1986
The Structural Basis of Ribosome Activity in Peptide Bond Synthesis
2000 StandoutScienceNobel
The yeast SEC17 gene product is functionally equivalent to mammalian alpha-SNAP protein.
1992 StandoutNobel
Effects on mRNA splicing of mutations in the 3' region of the Saccharomyces cerevisiae actin intron.
1987
The Yeast PRP6 Gene Encodes a U4/U6 Small Nuclear Ribonucleoprotein Particle (snRNP) Protein, and the PRP9 Gene Encodes a Protein Required for U2 snRNP Binding
1990 StandoutNobel
Accumulation of a Novel Spliceosomal Complex on Pre-mRNAs Containing Branch Site Mutations
1995
An Early Hierarchic Role of U1 Small Nuclear Ribonucleoprotein in Spliceosome Assembly
1988 Science
PRP4: a protein of the yeast U4/U6 small nuclear ribonucleoprotein particle.
1989
A novel role for a U5 snRNP protein in 3' splice site selection.
1995
The Chemistry of Self-Splicing RNA and RNA Enzymes
1987 StandoutScienceNobel
5' splice site selection in yeast: genetic alterations in base-pairing with U1 reveal additional requirements.
1988
A chemical modification/interference study of yeast pre-mRNA spliceosome assembly and splicing.
1988 StandoutNobel
Yeast pre-mRNA splicing requires a minimum distance between the 5' splice site and the internal branch acceptor site.
1987
Cloning and characterization of PSF, a novel pre-mRNA splicing factor.
1993
The yeast RNA gene products are essential for mRNA splicing in vitro
1986
A quantitative analysis of the effects of 5′ junction and TACTAAC box mutants and mutant combinations on yeast mRNA splicing
1985 StandoutNobel
Aminoacylation of Synthetic DNAs Corresponding to Escherichia coli Phenylalanine and Lysine tRNAs
1988 Science
Identification of Proteins That Interact with Exon Sequences, Splice Sites, and the Branchpoint Sequence during Each Stage of Spliceosome Assembly
1996
Synthetic lethal mutations suggest interactions between U5 small nuclear RNA and four proteins required for the second step of splicing.
1992
Spliceosome assembly involves the binding and release of U4 small nuclear ribonucleoprotein.
1988
Efficient Trans-Splicing of a Yeast Mitochondrial RNA Group II Intron Implicates a Strong 5′ Exon-Intron Interaction
1986 StandoutScienceNobel
RNA11 protein is associated with the yeast spliceosome and is localized in the periphery of the cell nucleus.
1988
Extensive interactions of PRP8 protein with the 5′ and 3′ splice sites during splicing suggest a role in stabilization of exon alignment by U5 snRNA.
1995
RNA11 Protein is Associated with the Yeast Spliceosome and is Localized in the Periphery of the Cell Nucleus
1988
Specific accessory sequences in Saccharomyces cerevisiae introns control assembly of pre-mRNAs into spliceosomes.
1987
A novel role for the 3' region of introns in pre-mRNA splicing of Saccharomyces cerevisiae.
1987 StandoutNobel
Yeast Pre-mRNA Splicing Requires a Minimum Distance between the 5′ Splice Site and the Internal Branch Acceptor Site
1987
Involvement of U6 snRNA in 5′ Splice Site Selection
1993 Science
Specific small nuclear RNAs are associated with yeast spliceosomes
1986 StandoutNobel
Yeast pre-messenger RNA splicing efficiency depends on critical spacing requirements between the branch point and 3′ splice site.
1986
The Mating of a Fly
1994 StandoutScienceNobel
A mutational analysis of spliceosome assembly: evidence for splice site collaboration during spliceosome formation.
1987
The canonical GU dinucleotide at the 5' splice site is recognized by p220 of the U5 snRNP within the spliceosome.
1996
An essential splicing factor, SLU7, mediates 3' splice site choice in yeast.
1992
Some cis- and trans-acting mutants for splicing target pre-mRNA to the cytoplasm
1989 StandoutNobel
A functional association between the 5' and 3' splice site is established in the earliest prespliceosome complex (E) in mammals.
1993
The yeast splicing factor Mud13p is a commitment complex component and corresponds to CBP20, the small subunit of the nuclear cap-binding complex.
1996 StandoutNobel
RNA splicing and intron turnover are greatly diminished by a mutant yeast branch point.
1986 StandoutNobel
Splicing of yeast nuclear pre-mRNA in vitro requires a functional 40S spliceosome and several extrinsic factors.
1987
Fractionation and characterization of a yeast mRNA splicing extract.
1986
Protein components specifically associated with prespliceosome and spliceosome complexes.
1992
Early commitment of yeast pre-mRNA to the spliceosome pathway.
1988 StandoutNobel
In vitro formation of a lariat structure containing a G2'-5'G linkage.
1987 StandoutNobel
Structural Insights into Group II Intron Catalysis and Branch-Site Selection
2002 StandoutScienceNobel
Messenger RNA Splicing in Yeast: Clues to Why the Spliceosome Is a Ribonucleoprotein
1991 Science
Electrophoresis of ribonucleoproteins reveals an ordered assembly pathway of yeast splicing complexes
1986 StandoutNatureNobel
5′ cleavage site in eukaryotic pre-mRNA splicing is determined by the overall 5′ splice region, not by the conserved 5′ GU
1987
Works of Andy Newman being referenced
RNA splicing: Out of the loop
1997
U5 snRNA interacts with exon sequences at 5′ and 3′ splice sites
1992
RNA Splicing: Activity in the spliceosome
1994
snRNA interactions at 5' and 3' splice sites monitored by photoactivated crosslinking in yeast spliceosomes.
1995
Molecular consequences of specific intron mutations on yeast mRNA splicing in vivo and in vitro
1985