Standout Papers
Citation Impact
Citing Papers
Mass of the postsynaptic density and enumeration of three key molecules
2005
A drug-controllable tag for visualizing newly synthesized proteins in cells and whole animals
2008 StandoutNobel
Modulation of Ca V 2.1 channels by Ca 2+ /calmodulin-dependent protein kinase II bound to the C-terminal domain
2007
RNA polymerase II trigger loop residues stabilize and position the incoming nucleotide triphosphate in transcription
2010 StandoutNobel
Global Identification and Characterization of Both O-GlcNAcylation and Phosphorylation at the Murine Synapse
2012
Energy Stress Regulates Hippo-YAP Signaling Involving AMPK-Mediated Regulation of Angiomotin-like 1 Protein
2014
Hippo-Independent Activation of YAP by the GNAQ Uveal Melanoma Oncogene through a Trio-Regulated Rho GTPase Signaling Circuitry
2014
Creating new fluorescent probes for cell biology
2002 StandoutNobel
Structure of a mammalian ryanodine receptor
2014 StandoutNatureNobel
Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions
2024 StandoutNobel
Structural Basis for Gating and Activation of RyR1
2016 StandoutNobel
The Mechanosensitive Ion Channel Piezo Inhibits Axon Regeneration
2019 StandoutNobel
Single-Molecule Discrimination of Discrete Perisynaptic and Distributed Sites of Actin Filament Assembly within Dendritic Spines
2010 StandoutNobel
α- and βCaMKII
2002
Dynamic personalities of proteins
2007 StandoutNature
Structural basis of long-term potentiation in single dendritic spines
2004 StandoutNature
Free and bound intracellular calmodulin measurements in cardiac myocytes
2006
Calcium's Role in Mechanotransduction during Muscle Development
2014 Standout
Calmodulin Kinase and L-Type Calcium ChannelsA Recipe for Arrhythmias?
2004
Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain
2016 StandoutNatureNobel
Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca2+ release channel
2007 StandoutNobel
Modulation of the Phosphorylation and Activity of Calcium/Calmodulin‐Dependent Protein Kinase II by Zinc
2000
A Ca2+-Binding Domain in RyR1 that Interacts with the Calmodulin Binding Site and Modulates Channel Activity
2005
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
Presynaptic CaMKII Is Necessary for Synaptic Plasticity in Cultured Hippocampal Neurons
2004
Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation
2013 Nature
CD45, CD148, and Lyp/Pep: critical phosphatases regulating Src family kinase signaling networks in immune cells
2009
The Human Transcription Factors
2018 Standout
Function and regulation of the Mediator complex
2011
LTP Requires a Unique Postsynaptic SNARE Fusion Machinery
2013 StandoutNobel
The Presynaptic Active Zone
2012 StandoutNobel
Molecular basis of ancestral vertebrate electroreception
2017 StandoutNatureNobel
Small Conductance Ca2+-activated K+ Channels and Calmodulin
2003
Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
2015 Standout
Ubiquitin Ligase Activity of TFIIH and the Transcriptional Response to DNA Damage
2005 StandoutNobel
Autonomous activity of CaMKII is only transiently increased following the induction of long‐term potentiation in the rat hippocampus
2004
Preassociation of Calmodulin with Voltage-Gated Ca2+ Channels Revealed by FRET in Single Living Cells
2001
Piezos thrive under pressure: mechanically activated ion channels in health and disease
2017 StandoutNobel
Autoinhibitory control of the Ca V 1.2 channel by its proteolytically processed distal C‐terminal domain
2006
Crystal Structure of a Tetradecameric Assembly of the Association Domain of Ca2+/Calmodulin-Dependent Kinase II
2003
Structure and mechanism of the RNA polymerase II transcription machinery
2004
A modular switch for spatial Ca2+ selectivity in the calmodulin regulation of CaV channels
2008 Nature
Postsynaptic protein mobility in dendritic spines: Long-term regulation by synaptic NMDA receptor activation
2006
CaMKII Triggers the Diffusional Trapping of Surface AMPARs through Phosphorylation of Stargazin
2010
Chapter 4 Genetics and Molecular Pathophysiology of Nav1.7‐Related Pain Syndromes
2008
Calmodulin Suppresses Synaptotagmin-2 Transcription in Cortical Neurons*
2010 StandoutNobel
The Role of Chromatin during Transcription
2007 Standout
Calmodulin Controls Synaptic Strength via Presynaptic Activation of Calmodulin Kinase II
2010 StandoutNobel
The emerging roles of YAP and TAZ in cancer
2015
Cellular and Molecular Mechanisms of Pain
2009 StandoutNobel
Multiple sodium channels and their roles in electrogenesis within dorsal root ganglion neurons
2006
Mediator as a General Transcription Factor
2005 StandoutNobel
CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy
2006
ATP-Independent Luminal Oscillations and Release of Ca2+ and H+ from Mast Cell Secretory Granules: Implications for Signal Transduction
2003
Regulation of Calcium/Calmodulin-Dependent Protein Kinase II Activation by Intramolecular and Intermolecular Interactions
2004
Experience-Dependent Increase in CA1 Place Cell Spatial Information, But Not Spatial Reproducibility, Is Dependent on the Autophosphorylation of the α-Isoform of the Calcium/Calmodulin-Dependent Protein Kinase II
2007 StandoutNobel
The molecular basis of CaMKII function in synaptic and behavioural memory
2002
Mucin Granule Intraluminal Organization in Living Mucous/Goblet Cells
2005 StandoutNobel
Convergent CaMK and RacGEF signals control dendritic structure and function
2008
The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation
2010
Malleable machines take shape in eukaryotic transcriptional regulation
2008
Supramolecular Assemblies and Localized Regulation of Voltage-Gated Ion Channels
2009
Calcium Channel Regulation and Presynaptic Plasticity
2008
Calcium, Calmodulin, and Calcium-Calmodulin Kinase II: Heartbeat to Heartbeat and Beyond
2002
Calmodulin in Action
2002
Calcium Signaling
2007 Standout
Two Modes of Transcriptional Activation at Native Promoters by NF-κB p65
2009
The role of calmodulin as a signal integrator for synaptic plasticity
2005
Regulation of Synaptic Transmission by Presynaptic CaMKII and BK Channels
2008
Nociceptors: the sensors of the pain pathway
2010 StandoutNobel
A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis
2015
Calmodulin modulation of proteins involved in excitation-contraction coupling
2002
Modeling the assembly order of multimeric heteroprotein complexes
2018
Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
2013 Standout
Double Click Reaction for the Acquisition of a Highly Potent and Selective mPTPB Inhibitor
2010
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Pathophysiology of the Neuroregulation of Growth Hormone Secretion in Experimental Animals and the Human*
1998 Standout
Regulation of Cell Cycle Progression by Calcium/Calmodulin-Dependent Pathways
2003
Tfb6, a previously unidentified subunit of the general transcription factor TFIIH, facilitates dissociation of Ssl2 helicase after transcription initiation
2012 Nobel
Architecture of an RNA Polymerase II Transcription Pre-Initiation Complex
2013 StandoutScienceNobel
The Structure of a Transcribing T7 RNA Polymerase in Transition from Initiation to Elongation
2008 StandoutScienceNobel
The Role of Voltage-Gated Calcium Channels in Pancreatic β-Cell Physiology and Pathophysiology
2006
The neuronal connexin36 interacts with and is phosphorylated by CaMKII in a way similar to CaMKII interaction with glutamate receptors
2008
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
Calmodulin as an Ion Channel Subunit
2002
SWISS-MODEL: homology modelling of protein structures and complexes
2018 Standout
All-or-none potentiation at CA3-CA1 synapses
1998 StandoutNobel
Sodium Channels in Normal and Pathological Pain
2010
Long-Term Potentiation--A Decade of Progress?
1999 StandoutScience
Fast structural responses of gap junction membrane domains to AB5 toxins
2013 StandoutNobel
Hippo Pathway Regulation of Gastrointestinal Tissues
2014
Dual Effect of ATP in the Activation Mechanism of Brain Ca2+/Calmodulin-Dependent Protein Kinase II by Ca2+/Calmodulin
2001
Molecular determinants of Ca 2+ /calmodulin-dependent regulation of Ca v 2.1 channels
2003
N-Heterocyclic Carbenes in Late Transition Metal Catalysis
2009 Standout
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Inositol hexakisphosphate suppresses excitatory neurotransmission via synaptotagmin-1 C2B domain in the hippocampal neuron
2012 StandoutNobel
The molecular basis of eukaryotic transcription
2007 Nobel
Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies
2018
Ischemic Cell Death in Brain Neurons
1999 Standout
Gold(I)-Mediated Inhibition of Protein Tyrosine Phosphatases: A Detailed in Vitro and Cellular Study
2008
Salicylic Acid Based Small Molecule Inhibitor for the Oncogenic Src Homology-2 Domain Containing Protein Tyrosine Phosphatase-2 (SHP2)
2010
Native Piezo2 Interactomics Identifies Pericentrin as a Novel Regulator of Piezo2 in Somatosensory Neurons
2016
Regulation of Exocytosis through Ca2+/ATP-Dependent Binding of Autophosphorylated Ca2+/Calmodulin-Activated Protein Kinase II to Syntaxin 1A
2002
Apoptotic surge of potassium currents is mediated by p38 phosphorylation of Kv2.1
2007
Autophosphorylation at Thr 286 of the α Calcium-Calmodulin Kinase II in LTP and Learning
1998 Science
Structural diversity of calmodulin binding to its target sites
2013
Role of the N- and C-Lobes of Calmodulin in the Activation of Ca2+/Calmodulin-Dependent Protein Kinase II
2008
Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging
2008 Standout
Hypermorphic mutation of the voltage-gated sodium channel encoding gene Scn10a causes a dramatic stimulus-dependent neurobehavioral phenotype
2011 StandoutNobel
Ca 2+ /calmodulin-dependent protein kinase II (CaMKII) is activated by calmodulin with two bound calciums
2006
Chemical Glycoproteomics
2016 StandoutNobel
Regulation of Voltage-Gated Ca 2+ Channels by Calmodulin
2005
Glyco-seek: Ultrasensitive Detection of Protein-Specific Glycosylation by Proximity Ligation Polymerase Chain Reaction
2016 StandoutNobel
ATP-sensitive potassium channel (K ATP )–dependent regulation of cardiotropic viral infections
2011 StandoutNobel
Works of Andy Hudmon being referenced
Serum deprivation inhibits the transcriptional co-activator YAP and cell growth via phosphorylation of the 130-kDa isoform of Angiomotin by the LATS1/2 protein kinases
2013
CaMKII tethers to L-type Ca2 + channels, establishing a local and dedicated integrator of Ca2 + signals for facilitation
2005
Structure, inhibitor, and regulatory mechanism of Lyp, a lymphoid-specific tyrosine phosphatase implicated in autoimmune diseases
2007
Effects of short-term cortisol infusion on growth hormone-releasing hormone stimulation of growth hormone release in sheep
1995
Three-dimensional Reconstructions of Calcium/Calmodulin-dependent (CaM) Kinase IIα and Truncated CaM Kinase IIα Reveal a Unique Organization for Its Structural Core and Functional Domains
2000
Molecular Characterization of Calmodulin Trapping by Calcium/Calmodulin-dependent Protein Kinase II
2001
CaMKII Controls Whether Touch Is Painful
2015
Revised Subunit Structure of Yeast Transcription Factor IIH (TFIIH) and Reconciliation with Human TFIIH
2003 StandoutNobel
Light scattering and transmission electron microscopy studies reveal a mechanism for calcium/calmodulin‐dependent protein kinase II self‐association
2001
Calmodulin Regulates Current Density and Frequency-Dependent Inhibition of Sodium Channel Nav1.8 in DRG Neurons
2006
A Mechanism for Ca 2+ /Calmodulin-Dependent Protein Kinase II Clustering at Synaptic and Nonsynaptic Sites Based on Self-Association
2005
Identification of Domains Essential for the Assembly of Calcium/Calmodulin-dependent Protein Kinase II Holoenzymes
1998
Excitotoxic neuroprotection and vulnerability with CaMKII inhibition
2011
Phosphorylation of Sodium Channel Nav1.8 by p38 Mitogen-Activated Protein Kinase Increases Current Density in Dorsal Root Ganglion Neurons
2008
Chemical Quenched Flow Kinetic Studies Indicate an Intraholoenzyme Autophosphorylation Mechanism for Ca2+/Calmodulin-dependent Protein Kinase II
2002
Inactivation and Self-association of Ca /Calmodulin-dependent Protein Kinase II during Autophosphorylation
1996
Head Module Control of Mediator Interactions
2006 StandoutNobel
Cardiac sodium channel palmitoylation regulates channel availability and myocyte excitability with implications for arrhythmia generation
2016
Voltage-Gated Sodium Channel Nav1.6 Is Modulated by p38 Mitogen-Activated Protein Kinase
2005
Molecular Basis of Calmodulin Tethering and Ca2+-dependent Inactivation of L-type Ca2+ Channels
2001
Ca2+/Calmodulin Kinase II Translocates in a Hippocampal Slice Model of Ischemia
1995
Structure–function of the multifunctional Ca2+/calmodulin-dependent protein kinase II
2002
Neuronal Ca2+/Calmodulin-Dependent Protein Kinase II: The Role of Structure and Autoregulation in Cellular Function
2002
Molecular basis of calmodulin tethering and Ca2+-dependent inactivation of L-type Ca2+ channels.
2001