Citation Impact
Citing Papers
Checkpoint Proteins Control Survival of the Postmitotic Cells in Caenorhabditis elegans
2006 Science
Triggering a Cell Shape Change by Exploiting Preexisting Actomyosin Contractions
2012 StandoutScienceNobel
The C. elegans heterochronic gene lin-28 coordinates the timing of hypodermal and somatic gonadal programs for hermaphrodite reproductive system morphogenesis
2019 StandoutNobel
A critical role of VMP1 in lipoprotein secretion
2019
Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism
2024 StandoutNobel
Endothelial apoptosis in Braf-deficient mice
1997
Defective recycling of synaptic vesicles in synaptotagmin mutants of Caenorhabditis elegans
1995 StandoutNatureNobel
RIM Proteins Tether Ca2+ Channels to Presynaptic Active Zones via a Direct PDZ-Domain Interaction
2011 StandoutNobel
The eggshell is required for meiotic fidelity, polar-body extrusion and polarization of the C. elegansembryo
2006
Oncogenic potential of a C.eleganscdc25 gene is demonstrated by a gain-of-function allele
2002
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Eggshell Chitin and Chitin-Interacting Proteins Prevent Polyspermy in C. elegans
2010
A cytokinesis furrow is positioned by two consecutive signals
2005 Nature
Stu-71air-2 is a C. elegans aurora homologue essential for chromosome segregation during embryonic and post-embryonic development
1999
The Caenorhabditis elegans locus lin-15, a negative regulator of a tyrosine kinase signaling pathway, encodes two different proteins.
1994 StandoutNobel
Differential Regulation of Raf-1, A-Raf, and B-Raf by Oncogenic Ras and Tyrosine Kinases
1997
CUL-2 is required for the G1-to-S-phase transition and mitotic chromosome condensation in Caenorhabditis elegans
1999
Mammalian Ras interacts directly with the serine/threonine kinase raf
1993 Standout
Vulval development in Caenorhabditis elegans
1997
Reciprocal EGF signaling back to the uterus from the induced C. elegans vulva coordinates morphogenesis of epithelia
1999
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses
2012 StandoutNobel
The C. elegans ksr-1 gene encodes a novel raf-related kinase involved in Ras-mediated signal transduction
1995
Heterochronic Genes Control Cell Cycle Progress and Developmental Competence of C. elegans Vulva Precursor Cells
1996 StandoutNobel
Conservation and reiteration of a kinase cascade
1993
Control and integration of cell signaling pathways during C. Elegans vulval development
1996
Ras - a versatile cellular switch
1998
Degradation of Cdc25A by β-TrCP during S phase and in response to DNA damage
2003 StandoutNatureNobel
Purification of a Ras-dependent Mitogen-activated Protein Kinase Kinase Kinase from Bovine Brain Cytosol and Its Identification as a Complex of B-Raf and 14-3-3 Proteins
1995
The Hallmarks of Cancer
2000 Standout
A soma-to-germline transformation in long-lived Caenorhabditis elegans mutants
2009 StandoutNatureNobel
Identification of genes expressed in C. elegans touch receptor neurons
2002 StandoutNatureNobel
Ras pathways in Caenorhabditis elegans
1995
Genetics of signal transduction in invertebrates
1994
Trans-splicing in C. elegans generates the negative RNAi regulator ERI-6/7
2008 StandoutNatureNobel
Somatic misexpression of germline P granules and enhanced RNA interference in retinoblastoma pathway mutants
2005 StandoutNatureNobel
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
A Global Profile of Germline Gene Expression in C. elegans
2000
EGG-3 Regulates Cell-Surface and Cortex Rearrangements during Egg Activation in Caenorhabditis elegans
2007
Dynamics and functions of lipid droplets
2018 Standout
Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro
1993 Nature
Patterning of the Caenorhabditis elegans head region by the Pax-6 family member vab-3
1995 StandoutNatureNobel
Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer
2009
SAX-7/L1CAM and HMR-1/cadherin function redundantly in blastomere compaction and non-muscle myosin accumulation during Caenorhabditis elegans gastrulation
2010
Identification of in vivo mRNA targets of GLD-1, a maxi-KH motif containing protein required for C. elegans germ cell development
2001
Murine Ksr interacts with MEK and inhibits Ras-induced transformation
1998
The RING finger/B-Box factor TAM-1 and a retinoblastoma-like protein LIN-35 modulate context-dependent gene silencing in Caenorhabditis elegans
1999 StandoutNobel
The anaphase-promoting complex: it's not just for mitosis any more
2002
Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
2004 StandoutNatureNobel
The 3Ms of central spindle assembly: microtubules, motors and MAPs
2008
Asymmetric Segregation of PIE-1 in C. elegans Is Mediated by Two Complementary Mechanisms that Act through Separate PIE-1 Protein Domains
2000
Immunofluorescence Microscopy
2012
An FGF receptor signaling pathway is required for the normal cell migrations of the sex myoblasts in C. elegans hermaphrodites
1995 StandoutNobel
The C. elegans gene lin-44, which controls the polarity of certain asymmetric cell divisions, encodes a Wnt protein and acts cell nonautonomously
1995 StandoutNobel
A Cell Cycle Timer for Asymmetric Spindle Positioning
2009
WRM-1 Activates the LIT-1 Protein Kinase to Transduce Anterior/Posterior Polarity Signals in C. elegans
1999 StandoutNobel
lin-35 and lin-53, Two Genes that Antagonize a C. elegans Ras Pathway, Encode Proteins Similar to Rb and Its Binding Protein RbAp48
1998 StandoutNobel
A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans
2004 StandoutNatureNobel
The TRA-1A Sex Determination Protein of C. elegans Regulates Sexually Dimorphic Cell Deaths by Repressing the egl-1 Cell Death Activator Gene
1999 StandoutNobel
TMEM41B Is a Pan-flavivirus Host Factor
2020 StandoutNobel
The Survivin-like C. elegans BIR-1 Protein Acts with the Aurora-like Kinase AIR-2 to Affect Chromosomes and the Spindle Midzone
2000 StandoutNobel
Control of cell fates in the central body region of C. elegans by the homeobox gene lin-39
1993 StandoutNobel
Signal transduction and cell fate specification during Caenorhabditis elegans vulval development
1994
Binding of 14-3-3 Proteins to the Protein Kinase Raf and Effects on Its Activation
1994 Science
Caenorhabditis elegans SUR-5, a Novel but Conserved Protein, Negatively Regulates LET-60 Ras Activity during Vulval Induction
1998
Small GTP-Binding Proteins
2001 Standout
Role of the Caenorhabditis elegans Shc Adaptor Protein in the c-Jun N-Terminal Kinase Signaling Pathway
2008
Origin, properties, and regulated expression of multiple mRNAs encoded by the protein kinase C1 gene of Caenorhabditis elegans.
1994
Ras recruits Raf-1 to the plasma membrane for activation by tyrosine phosphorylation.
1995
Suppression of activated Let-60 ras protein defines a role of Caenorhabditis elegans Sur-1 MAP kinase in vulval differentiation.
1994
A Point Mutation in the Extracellular Domain Activates LET-23, the Caenorhabditis elegans Epidermal Growth Factor Receptor Homolog
1996
A β-amino-cyclodextrin monolayer-modified Au electrode: a command surface for the amperometric and microgravimetric transduction of optical signals recorded by a photoisomerizable bipyridinium–azobenzene diad
1997
SQV-7, a protein involved in Caenorhabditis elegans epithelial invagination and early embryogenesis, transports UDP-glucuronic acid, UDP- N - acetylgalactosamine, and UDP-galactose
2001 StandoutNobel
Mesoderm induction by activin requires FGF-mediated intracellular signals
1994
The Caenorhabditis elegans gene lin-1 encodes an ETS-domain protein and defines a branch of the vulval induction pathway.
1995 StandoutNobel
lin-25, a gene required for vulval induction in Caenorhabditis elegans.
1995
Chiroptical Molecular Switches
2000 StandoutNobel
Three genes of the MAP kinase cascade, mek-2, mpk-1/sur-1 and let-60 ras, are required for meiotic cell cycle progression in Caenorhabditis elegans
1995
A feedback circuit involving let-7-family miRNAs and DAF-12 integrates environmental signals and developmental timing in Caenorhabditis elegans
2009 StandoutNobel
Specific requirement for two ADF/cofilin isoforms in distinct actin-dependent processes inCaenorhabditis elegans
2003
The Temporal Patterning MicroRNA let-7 Regulates Several Transcription Factors at the Larval to Adult Transition in C. elegans
2005
Kinase requirements in human cells: III. Altered kinase requirements inVHL−/− cancer cells detected in a pilot synthetic lethal screen
2008 StandoutNobel
The Taxonomy of Developmental Control in Caenorhabditis elegans
1998 StandoutScienceNobel
Role of Polo-like kinase in the degradation of early mitotic inhibitor 1, a regulator of the anaphase promoting complex/cyclosome
2004 StandoutNobel
Binding of Neuroligins to PSD-95
1997 StandoutScienceNobel
Partial purification of a mitogen-activated protein kinase kinase activator from bovine brain. Identification as B-Raf or a B-Raf-associated activity.
1994
Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells
2006 StandoutNobel
MEK-2, a Caenorhabditis elegans MAP kinase kinase, functions in Ras-mediated vulval induction and other developmental events.
1995
A Human Protein Selected for Interference with Ras Function Interacts Directly with Ras and Competes with Raf1
1995
Elucidation of the role of breathless, a Drosophila FGF receptor homolog, in tracheal cell migration.
1994
sqv mutants of Caenorhabditis elegans are defective in vulval epithelial invagination
1999 StandoutNobel
RNA as a target of double-stranded RNA-mediated genetic interference in Caenorhabditis elegans
1998 StandoutNobel
ralGDS family members interact with the effector loop of ras p21.
1994
Mosaic analysis of the let-23 gene function in vulval induction of Caenorhabditis elegans
1995
GTP-dependent association of Raf-1 with Ha-Ras: identification of Raf as a target downstream of Ras in mammalian cells.
1993
Genetic Control of Programmed Cell Death in the Nematode Caenorhabditis Elegans
1994
The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans
1995 StandoutNobel
The β-catenin homolog BAR-1 and LET-60 Ras coordinately regulate the Hox gene lin-39 during Caenorhabditis elegans vulval development
1998
Mitogen-Activated Protein Kinase: Conservation of a Three-Kinase Module From Yeast to Human
1999 Standout
14-3-3 Is Not Essential for Raf-1 Function: Identification of Raf-1 Proteins That Are Biologically Activated in a 14-3-3- and Ras-Independent Manner
1995
The lin-15 locus encodes two negative regulators of Caenorhabditis elegans vulval development.
1994
A Localized Wnt Signal Orients Asymmetric Stem Cell Division in Vitro
2013 StandoutScienceNobel
A MAP kinase homolog, mpk-1, is involved in ras-mediated induction of vulval cell fates in Caenorhabditis elegans.
1994 StandoutNobel
The Caenorhabditis elegans gene mek-2 is required for vulval induction and encodes a protein similar to the protein kinase MEK.
1995 StandoutNobel
The mitogen-activated protein kinase cascade is activated by B-Raf in response to nerve growth factor through interaction with p21ras.
1994
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Cell fate patterning during C. elegans vulval development
1993
Next‐Generation Sequencing for Identification of EMS‐Induced Mutations inCaenorhabditis elegans
2017
Aurora/Ipl1p-related kinases, a new oncogenic family of mitotic serine-threonine kinases
1999
Gain-of-Function Mutations in the Caenorhabditis elegans lin-1 ETS Gene Identify a C-Terminal Regulatory Domain Phosphorylated by ERK MAP Kinase
1998 StandoutNobel
Works of Andy Golden being referenced
Cortical granule exocytosis in C. elegans is regulated by cell cycle components including separase
2007
The polo-like kinase PLK-1 is required for nuclear envelope breakdown and the completion of meiosis inCaenorhabditis elegans
2000
Rapid and Efficient Identification ofCaenorhabditis elegansLegacy Mutations Using Hawaiian SNP-Based Mapping and Whole-Genome Sequencing
2015
Cytoplasmic flow and the establishment of polarity in C. elegans 1-cell embryos
2000
RNA-Mediated Interference of acdc25Homolog inCaenorhabditis elegansResults in Defects in the Embryonic Cortical Membrane, Meiosis, and Mitosis
1999
Molecular Genetics of Proto-oncogenes and Candidate Tumor Suppressors in Caenorhabditis elegans
1994
Components of the Spindle Assembly Checkpoint Regulate the Anaphase-Promoting Complex During Meiosis inCaenorhabditis elegans
2006
Lipid droplet and peroxisome biogenesis occur at the same ER subdomains
2018
The Caenorhabditis elegans par-5 Gene Encodes a 14-3-3 Protein Required for Cellular Asymmetry in the Early Embryo
2002
The four cdc25 genes from the nematode Caenorhabditis elegans
1998
An RNAi-Based Suppressor Screen Identifies Interactors of the Myt1 Ortholog ofCaenorhabditis elegans
2014
CDC‐25.1 regulates germline proliferation in Caenorhabditis elegans
2002
C. elegans lin-45 raf gene participates in let-60 ras-stimulated vulval differentiation
1993 Nature
Metaphase to Anaphase (mat) Transition–Defective Mutants inCaenorhabditis elegans
2000
Developmental defects observed in hypomorphic anaphase-promoting complex mutants are linked to cell cycle abnormalities
2003
AIR-2: An Aurora/Ipl1-related Protein Kinase Associated with Chromosomes and Midbody Microtubules Is Required for Polar Body Extrusion and Cytokinesis in Caenorhabditis elegans Embryos
1998
TheC. elegansMyt1 ortholog is required for the proper timing of oocyte maturation
2006
A conserved family of proteins facilitates nascent lipid droplet budding from the ER
2015
A highly conserved centrosomal kinase, AIR-1, is required for accurate cell cycle progression and segregation of developmental factors in Caenorhabditis elegans embryos
1998