Citation Impact
Citing Papers
Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve
2011 Standout
Genetic Influences on Brain Gene Expression in Rats Selected for Tameness and Aggression
2014 StandoutNobel
Partial Response and Nonresponse to Antidepressant Therapy
2002
Stress Hormone-Related Psychopathology: Pathophysiological and Treatment Implications
2001
A Meta-Analysis of Cytokines in Major Depression
2009 Standout
Reduced Stress-Sensitivity or Increased Reward Experience: The Psychological Mechanism of Response to Antidepressant Medication
2008
Antidepressant Drug Effects and Depression Severity
2010 Standout
Expression of neuronal nitric oxide synthase in the hippocampal formation in affective disorders
2008
Metabolic dysregulation in vitamin E and carnitine shuttle energy mechanisms associate with human frailty
2019
Depression
2018 Standout
From stress to inflammation and major depressive disorder: A social signal transduction theory of depression.
2014 Standout
Severe depression is associated with increased microglial quinolinic acid in subregions of the anterior cingulate gyrus: Evidence for an immune-modulated glutamatergic neurotransmission?
2011
Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression
2009 Standout
Changes in the immune system in depression and dementia: causal or co‐incidental effects?
2001
Low nNOS protein in the locus coeruleus in major depression
2004
Metyrapone as Additive Treatment in Major Depression
2004
S33005, a Novel Ligand at Both Serotonin and Norepinephrine Transporters: II. Behavioral Profile in Comparison with Venlafaxine, Reboxetine, Citalopram, and Clomipramine
2001
The Corticosteroid Receptor Hypothesis of Depression
2000 Standout
Forced swimming test in mice: a review of antidepressant activity
2004
Glutamate and Depression
2003
Antiglucocorticoid drugs in the treatment of depression
2001
Increased Vulnerability to Depressive-Like Behavior of Mice with Decreased Expression of VGLUT1
2009
Skeletal Muscle PGC-1α1 Modulates Kynurenine Metabolism and Mediates Resilience to Stress-Induced Depression
2014
Chronic Mild Stress (CMS) Revisited: Consistency and Behavioural-Neurobiological Concordance in the Effects of CMS
2005 Standout
Antidepressant- and anxiolytic-like effects of selective neuronal NOS inhibitor 1-(2-trifluoromethylphenyl)-imidazole in mice
2003
Kynurenines in the mammalian brain: when physiology meets pathology
2012
The physiology and pathophysiology of nitric oxide in the brain
2005
NMDA Receptor Blockade by Ketamine Abrogates Lipopolysaccharide-Induced Depressive-Like Behavior in C57BL/6J Mice
2013
Suicidality and Activation of the Kynurenine Pathway of Tryptophan Metabolism
2016
Plasma Concentrations of Interleukin-1β, Interleukin-6, Soluble Interleukin-2 Receptor and Tumor Necrosis Factor α of Depressed Patients in Japan
2001
Pharmacokinetics of selective serotonin reuptake inhibitors
2000
Mechanisms and Functional Implications of Adult Neurogenesis
2008 Standout
Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse
2009 Standout
Interactions between the microbiota, immune and nervous systems in health and disease
2017 Standout
Is Caregiving Hazardous to One's Physical Health? A Meta-Analysis.
2003 Standout
Strain and Gender Specific Effects in the Forced Swim Test: Effects of Previous Stress Exposure
2003
Pharmacological Profile of the 5‐HT2C Receptor Agonist WAY‐163909; Therapeutic Potential in Multiple Indications
2006
β-adrenoceptor mediated surgery-induced production of pro-inflammatory cytokines in rat microglia cells
2010
The kynurenine pathway and the brain: Challenges, controversies and promises
2016
Feeling Strained? Influence of Genetic Background on Depression-Related Behavior in Mice: A Review
2006
IDO chronic immune activation and tryptophan metabolic pathway: A potential pathophysiological link between depression and obesity
2017
Diagnosis and Treatment of Low Back Pain: A Joint Clinical Practice Guideline from the American College of Physicians and the American Pain Society
2007 Standout
β-Adrenergic Receptor Antagonism Prevents Anxiety-Like Behavior and Microglial Reactivity Induced by Repeated Social Defeat
2011
Are the Dorsal and Ventral Hippocampus Functionally Distinct Structures?
2010 Standout
Functional implications of decreases in neurogenesis following chronic mild stress in mice
2007
Evaluation of Outcomes With Citalopram for Depression Using Measurement-Based Care in STAR*D: Implications for Clinical Practice
2006 Standout
Hallmarks of aging: An expanding universe
2023 Standout
The Concept of Depression as a Dysfunction of the Immune System
2010
Myeloid-derived suppressor cells in the era of increasing myeloid cell diversity
2021 Standout
The olfactory bulbectomised rat as a model of depression
2005
PLASMA INFLAMMATORY CYTOKINE RESPONSE TO SURGICAL TRAUMA IN CHRONIC DEPRESSED PATIENTS
2001
Immune modulation of learning, memory, neural plasticity and neurogenesis
2010
Microglia and CNS Interleukin-1: Beyond Immunological Concepts
2018
The neuronal insulin sensitizer dicholine succinate reduces stress-induced depressive traits and memory deficit: possible role of insulin-like growth factor 2
2012
The Pharmacology and Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”)
2003 Standout
Chronic treatment with the atypical antidepressant tianeptine attenuates sickness behavior induced by peripheral but not central lipopolysaccharide and interleukin-1β in the rat
2001
Stress-Induced Anhedonia in Mice is Associated with Deficits in Forced Swimming and Exploration
2004
Assessing antidepressant activity in rodents: recent developments and future needs
2002
GABAB Receptor Antagonist-Mediated Antidepressant-Like Behavior Is Serotonin-Dependent
2004
Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis
2015 Standout
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
Role of pro-inflammatory cytokines released from microglia in neurodegenerative diseases
2011
A Distinct Profile of Tryptophan Metabolism along the Kynurenine Pathway Downstream of Toll-Like Receptor Activation in Irritable Bowel Syndrome
2012
Inflammation and depression: a causal or coincidental link to the pathophysiology?
2017
Immune attack: the role of inflammation in Alzheimer disease
2015 Standout
Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies
2013 Standout
Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson’s Disease
2016 Standout
Glutamate neurotoxicity and diseases of the nervous system
1988 Standout
Genetic background, nature of event, and time of exposure to event direct the phenotypic expression of a particular genotype
2004
The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner
2012 Standout
Cytokines and depression: fortuitous or causative association?
1999
Stress-Induced Recruitment of Bone Marrow-Derived Monocytes to the Brain Promotes Anxiety-Like Behavior
2013
Depression as a Microglial Disease
2015
Chronic Mild Stress in Mice Decreases Peripheral Cytokine and Increases Central Cytokine Expression Independently of IL-10 Regulation of the Cytokine Network
2002
A Meta-Analysis of Cytokines in Alzheimer's Disease
2010
Host microbiota constantly control maturation and function of microglia in the CNS
2015 Standout
Stress and the brain: from adaptation to disease
2005 Standout
A study on nitric oxide, β-adrenergic receptors and antioxidant status in the polymorphonuclear leukocytes from the patients of depression
2002
Microglia and neurodegeneration: The role of systemic inflammation
2012
Role of the Kynurenine Metabolism Pathway in Inflammation-Induced Depression: Preclinical Approaches
2016
Cytokines as mediators of depression: What can we learn from animal studies?
2005
Copper-Zinc Superoxide Dismutase (SOD1) Is Released by Microglial Cells and Confers Neuroprotection against 6-OHDA Neurotoxicity
2012 Standout
Eating ourselves to death (and despair): The contribution of adiposity and inflammation to depression
2010
The effects of stress exposure on the hypothalamic–pituitary–adrenal axis, thymus, thyroid hormones and glucose levels
2002
Behavioral and neurochemical characterization of α2A-adrenergic receptor knockout mice
2002 StandoutNobel
Major Depressive Disorder
2008 Standout
Effects of the probiotic Bifidobacterium infantis in the maternal separation model of depression
2010
Potential antidepressant-like effect of MTEP, a potent and highly selective mGluR5 antagonist
2005
Kynurenine pathway metabolism and the microbiota-gut-brain axis
2016
Differential behavioral effects of the antidepressants reboxetine, fluoxetine, and moclobemide in a modified forced swim test following chronic treatment
2005
Mind-altering microorganisms: the impact of the gut microbiota on brain and behaviour
2012 Standout
The kynurenine pathway and neurodegenerative disease
2015
Cancer-related fatigue—mechanisms, risk factors, and treatments
2014 Standout
Enhanced sympathetic outflow and decreased baroreflex sensitivity are associated with intermittent hypoxia-induced systemic hypertension in conscious rats
2006
The new ‘5-HT’ hypothesis of depression: Cell-mediated immune activation induces indoleamine 2,3-dioxygenase, which leads to lower plasma tryptophan and an increased synthesis of detrimental tryptophan catabolites (TRYCATs), both of which contribute to the onset of depression
2010
Gut Microbiota Regulation of Tryptophan Metabolism in Health and Disease
2018 Standout
A review on the oxidative and nitrosative stress (O&NS) pathways in major depression and their possible contribution to the (neuro)degenerative processes in that illness
2010 Standout
Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond
2019 Standout
From inflammation to sickness and depression: when the immune system subjugates the brain
2007 Standout
The tail suspension test as a model for assessing antidepressant activity: Review of pharmacological and genetic studies in mice
2005
The molecular neurobiology of depression
2008 StandoutNature
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
Effects of antidepressants on the production of cytokines
2002
Cytokine, Sickness Behavior, and Depression
2006
The Intestinal Microbiota Affect Central Levels of Brain-Derived Neurotropic Factor and Behavior in Mice
2011 Standout
Prevention of chronic stress-induced depression-like behavior by inducible nitric oxide inhibitor
2008
Tryptophan 2,3-dioxygenase and indoleamine 2,3-dioxygenase 1 make separate, tissue-specific contributions to basal and inflammation-induced kynurenine pathway metabolism in mice
2016
Cytokine imbalance in the pathophysiology of major depressive disorder
2007
Inflammation in obesity, diabetes, and related disorders
2022 Standout
Mouse chronic social stress increases blood and brain kynurenine pathway activity and fear behaviour: Both effects are reversed by inhibition of indoleamine 2,3-dioxygenase
2015
Locomotor reactivity to a novel environment and sensitivity to MK-801 in five strains of mice
2008
Neurodevelopmental Outcomes of Very Low-Birth-Weight Infants With Necrotizing Enterocolitis
2007
Association between Plasma IL-6 Response to Acute Stress and Early-Life Adversity in Healthy Adults
2010
The role of inflammation in depression: from evolutionary imperative to modern treatment target
2015 Standout
Can Meditation Slow Rate of Cellular Aging? Cognitive Stress, Mindfulness, and Telomeres
2009 StandoutNobel
Immune Players in the CNS: The Astrocyte
2013
Central Nervous System Infection with Borna Disease Virus Causes Kynurenine Pathway Dysregulation and Neurotoxic Quinolinic Acid Production
2017
Marine Indole Alkaloids: Potential New Drug Leads for the Control of Depression and Anxiety
2010 Standout
Microglia Function in the Central Nervous System During Health and Neurodegeneration
2017 Standout
Altered colonic function and microbiota profile in a mouse model of chronic depression
2013
Subcellular Partitioning and Intramacrophage Selectivity of Antimicrobial Compounds against Mycobacterium tuberculosis
2017 StandoutNobel
Pathophysiology of Sleep Apnea
2010 Standout
How important is tryptophan in human health?
2017
Requirement of Hippocampal Neurogenesis for the Behavioral Effects of Antidepressants
2003 StandoutScience
Impact of Plasma Kynurenine Level on Functional Capacity and Outcome in Heart Failure ― Results From Studies Investigating Co-morbidities Aggravating Heart Failure (SICA-HF) ―
2016
Physiology of Microglia
2011 Standout
Works of Andrew Harkin being referenced
Tryptophan depletion in depressed patients occurs independent of kynurenine pathway activation
2012
An Appraisal of the Pharmacological and Toxicological Effects of a Single Oral Administration of 3,4‐Methylenedioxymethamphetamine (MDMA) in the Rat
1997
Methylenedioxymethamphetamine-induced suppression of interleukin-1β and tumour necrosis factor-α is not mediated by serotonin
2001
Noradrenaline reuptake inhibitors limit neuroinflammation in rat cortex following a systemic inflammatory challenge: implications for depression and neurodegeneration
2008
Olfactory Bulbectomy Provokes a Suppression of Interleukin-1β and Tumour Necrosis Factor-α Production in Response to an in vivo Challenge with Lipopolysaccharide: Effect of Chronic Desipramine Treatment
1999
Reboxetine attenuates forced swim test-induced behavioural and neurochemical alterations in the rat
1999
C-reactive protein predicts fatigue independently of depression in breast cancer patients prior to chemotherapy
2013
Serotonergic mediation of the antidepressant-like effects of nitric oxide synthase inhibitors
2003
A study of VitalView™ for behavioural and physiological monitoring in laboratory rats
2002
Metyrapone displays antidepressant-like properties in preclinical paradigms
1999
Lipids and essential fatty acids in patients presenting with self-harm
2007
Activity and onset of action of reboxetine and effect of combination with sertraline in an animal model of depression
1999
Stress-related regulation of the kynurenine pathway: Relevance to neuropsychiatric and degenerative disorders
2015
The β2-adrenoceptor agonist clenbuterol elicits neuroprotective, anti-inflammatory and neurotrophic actions in the kainic acid model of excitotoxicity
2010
Olfactory bulbectomy in mice induces alterations in exploratory behavior
2004
Characterization of d-fenfluramine-induced hypothermia: evidence for multiple sites of action
2000
Effect of Subchronic Antidepressant Treatments on Behavioral, Neurochemical, and Endocrine Changes in the Forced-Swim Test
2000
Noradrenaline acting at central β-adrenoceptors induces interleukin-10 and suppressor of cytokine signaling-3 expression in rat brain: Implications for neurodegeneration
2010
Inhibition of stress-induced hepatic tryptophan 2,3-dioxygenase exhibits antidepressant activity in an animal model of depressive behaviour
2014
Noradrenaline reuptake inhibitors inhibit expression of chemokines IP-10 and RANTES and cell adhesion molecules VCAM-1 and ICAM-1 in the CNS following a systemic inflammatory challenge
2010
Poly I:C-induced activation of the immune response is accompanied by depression and anxiety-like behaviours, kynurenine pathway activation and reduced BDNF expression
2012
Modulation of MK-801-induced behaviour by noradrenergic agents in mice
2001
Noradrenaline acting at β-adrenoceptors induces expression of IL-1β and its negative regulators IL-1ra and IL-1RII, and drives an overall anti-inflammatory phenotype in rat cortex
2010
Nitric oxide synthase inhibitors have antidepressant-like properties in mice
1999
A role for serotonin in the antidepressant activity of NG-Nitro-L-arginine, in the rat forced swimming test
2009
Prior exposure to methylenedioxyamphetamine (MDA) induces serotonergic loss and changes in spontaneous exploratory and amphetamine-induced behaviors in rats
2001
Varying responses to the rat forced-swim test under diurnal and nocturnal conditions
2000
Nitric oxide synthase inhibitors augment the effects of serotonin re-uptake inhibitors in the forced swimming test
2004
Effects of acute and chronic antidepressant administration on phencyclidine (PCP) induced locomotor hyperactivity
1999
Induction of indolamine 2,3-dioxygenase and kynurenine 3-monooxygenase in rat brain following a systemic inflammatory challenge: A role for IFN-γ?
2008
Reduction in preference for saccharin by repeated unpredictable stress in mice and its prevention by imipramine
2002
The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes
2012
Association of Increased Treg Cell Levels With Elevated Indoleamine 2,3‐Dioxygenase Activity and an Imbalanced Kynurenine Pathway in Interferon‐Positive Primary Sjögren's Syndrome
2016
Muscling In on Depression
2014
Physiological and behavioral responses to stress: what does a rat find stressful?
2002
A review of the relevance and validity of olfactory bulbectomy as a model of depression
2003