Citation Impact
Citing Papers
Untangling the ErbB signalling network
2001 Standout
Binding of Thrombin to Glycoprotein Ib Accelerates the Hydrolysis of Par-1 on Intact Platelets
2001
Thrombin Responses in Human Endothelial Cells
2000
New mechanisms in heptahelical receptor signaling to mitogen activated protein kinase cascades
2001 StandoutNobel
PAR3 is a cofactor for PAR4 activation by thrombin
2000 Nature
Thrombin Signaling in the Brain: The Role of Protease-Activated Receptors
2003
Clopidogrel with or without Omeprazole in Coronary Artery Disease
2010 Standout
Molecular mapping of thrombin‐receptor interactions
2001
Extracellular Mutations of Protease-Activated Receptor-1 Result in Differential Activation by Thrombin and Thrombin Receptor Agonist Peptide
2000
Recognition of Gram-negative bacteria and endotoxin by the innate immune system
1999
The GPIbα–thrombin interaction: far from crystal clear
2003
The Cytoplasmic Tails of Protease-activated Receptor-1 and Substance P Receptor Specify Sorting to Lysosomes versusRecycling
1999
High-resolution crystal structure of human protease-activated receptor 1
2012 StandoutNatureNobel
Thrombin receptor (PAR-1) antagonists. Solid-Phase synthesis of indole-Based peptide mimetics by anchoring to a secondary amide
2001
Molecular Cloning of Bomapin (Protease Inhibitor 10), a Novel Human Serpin That Is Expressed Specifically in the Bone Marrow
1995
PAR1 antagonism protects against experimental liver fibrosis. Role of proteinase receptors in stellate cell activation
2004
Effect of Solar Particle Event Radiation and Hindlimb Suspension on Gastrointestinal Tract Bacterial Translocation and Immune Activation
2012 StandoutNobel
Shiga-toxin-producing Escherichia coli and haemolytic uraemic syndrome
2005 Standout
Structure-Function Analysis of Protease-activated Receptor 4 Tethered Ligand Peptides
2000
PAR4, but Not PAR1, Signals Human Platelet Aggregation via Ca2+ Mobilization and Synergistic P2Y12 Receptor Activation
2006
Serine proteases and brain damage – is there a link?
2000
Protease‐activated receptors in hemostasis, thrombosis and vascular biology
2005
Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin
1999
The bone marrow niche for haematopoietic stem cells
2014 StandoutNature
Cathepsin G Activates Protease-activated Receptor-4 in Human Platelets
2000
Protease-activating Receptor-4 Induces Full Platelet Spreading on a Fibrinogen Matrix
2007
Identification of a Nuclear Targeting Domain in the Insertion between Helices C and D in Protease Inhibitor-10
1999
Cloning and characterization of hurpin (protease inhibitor 13): a new skin-specific, UV-repressible serine proteinase inhibitor of the ovalbumin serpin family
1999
Thrombin signalling and protease-activated receptors
2000 StandoutNature
Platelet Activation and Atherothrombosis
2007 Standout
Constitutive Protease-activated Receptor-2-mediated Migration of MDA MB-231 Breast Cancer Cells Requires Both β-Arrestin-1 and -2
2004 StandoutNobel
Protease-activated Receptors 1 and 4 Are Shut Off with Distinct Kinetics after Activation by Thrombin
2000
Tissue Kallikrein Inhibitors Based on the Sunflower Trypsin Inhibitor Scaffold – A Potential Therapeutic Intervention for Skin Diseases
2016 StandoutNobel
Toll-like receptors in the induction of the innate immune response
2000 StandoutNature
The ATP-gated P2X1 Receptor Plays a Pivotal Role in Activation of Aspirin-treated Platelets by Thrombin and Epinephrine
2008 StandoutNobel
Inhibition of Acrosin by Serpins. A Suicide Substrate Mechanism
1995
Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes
2005 StandoutNature
TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease
2000 Nature
PU.1 and Interferon Consensus Sequence-binding Protein Regulate the Myeloid Expression of the Human Toll-like Receptor 4 Gene
2000 StandoutNobel
Structural analysis of the lymphocyte-specific kinase Lck in complex with non-selective and Src family selective kinase inhibitors
1999
A dual thrombin receptor system for platelet activation
1998 Nature
Targeting proteinase-activated receptors: therapeutic potential and challenges
2012
Cholesterol efflux from Fu5AH hepatoma cells induced by plasma of subjects with or without coronary artery disease and non-insulin-dependent diabetes: importance of LpA-I:A-II particles and phospholipid transfer protein
1996
Unique Pathway of Thrombin-induced Platelet Aggregation Mediated by Glycoprotein Ib
2001
Teaching old receptors new tricks: biasing seven-transmembrane receptors
2010 StandoutNobel
Mechanisms of fibrosis: therapeutic translation for fibrotic disease
2012 Standout
Human Proteinase Inhibitor 9 (PI9) Is a Potent Inhibitor of Subtilisin A
1997
Structural diversity of G protein-coupled receptors and significance for drug discovery
2008
Binding of the β2 Adrenergic Receptor toN-Ethylmaleimide-sensitive Factor Regulates Receptor Recycling
2001 StandoutNobel
Identification of the DNA Binding Specificity and Potential Target Genes for the Farnesoid X-activated Receptor
2000
The creation of an antithrombotic surface by apyrase immobilization
2010 StandoutNobel
Platelets in atherothrombosis: lessons from mouse models
2005
β-Arrestins Regulate Protease-activated Receptor-1 Desensitization but Not Internalization or Down-regulation
2002 StandoutNobel
Lipopolysaccharide binding protein and soluble CD14 catalyze exchange of phospholipids.
1997
Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis
2011 Standout
The TNF and TNF Receptor Superfamilies
2001 Standout
Protease activated receptors: theme and variations
2001
Microenvironmental regulation of tumor progression and metastasis
2013 Standout
Characterisation of species differences in the platelet ADP and thrombin response
2005 StandoutNobel
Thrombin-induced platelet activation and its inhibition by anticoagulants with different modes of action
2003
Activation of Proteinase-Activated Receptor-2 by Human Kallikrein-Related Peptidases
2007
The relative importance of the ADP receptors, P2Y12 and P2Y1, in thrombin-induced platelet activation
2003 StandoutNobel
Soluble CD36 Ectodomain Binds Negatively Charged Diacylglycerol Ligands and Acts as a Co-Receptor for TLR2
2009 StandoutNobel
Structural Basis for Thrombin Activation of a Protease-Activated Receptor
2003
Thrombin‐Induced Activation of Cultured Rodent Microglia
2000
Persistent Protease-activated Receptor 4 Signaling Mediates Thrombin-induced Microglial Activation
2003
The immunopathogenesis of sepsis
2002 StandoutNature
Adenovector-Mediated Expression of Human Thrombopoietin cDNA in Immune-Compromised Mice: Insights into the Pathophysiology of Osteomyelofibrosis
1998
Platelet PAR1 receptor density—Correlation to platelet activation response and changes in exposure after platelet activation
2007 StandoutNobel
Muscle-Specific Pten Deletion Protects against Insulin Resistance and Diabetes
2005 StandoutNobel
Physical contact between lipopolysaccharide and Toll-like receptor 4 revealed by genetic complementation
2000 StandoutNobel
Cutting Edge: Ectopic Expression of CD40 Ligand on B Cells Induces Lupus-Like Autoimmune Disease
2002 StandoutNobel
How the protease thrombin talks to cells
1999
Platelet activation via PAR4 is involved in the initiation of thrombin generation and in clot elasticity development
2007 StandoutNobel
Serpin Structure, Mechanism, and Function
2002 Standout
Identification of Farnesoid X Receptor β as a Novel Mammalian Nuclear Receptor Sensing Lanosterol
2003 StandoutNobel
Crystal Structure of Human BPI and Two Bound Phospholipids at 2.4 Angstrom Resolution
1997 Science
Soluble CD14 acts as a shuttle in the neutralization of lipopolysaccharide (LPS) by LPS-binding protein and reconstituted high density lipoprotein.
1995
The GPIb thrombin-binding site is essential for thrombin-induced platelet procoagulant activity
2000
Localization and Regulation of Thrombopoietin mRNA Expression in Human Kidney, Liver, Bone Marrow, and Spleen Using In Situ Hybridization
1997
A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis
2012 StandoutNobel
The Intracellular Serpin Proteinase Inhibitor 6 Is Expressed in Monocytes and Granulocytes and Is a Potent Inhibitor of the Azurophilic Granule Protease, Cathepsin G
1999
Administration of a Potent Antagonist of Protease-Activated Receptor-1 (PAR-1) Attenuates Vascular Restenosis Following Balloon Angioplasty in Rats
2001
Shrink-Wrap Vesicles
2005 StandoutNobel
Role of the PAR4 Thrombin Receptor in Stabilizing Platelet-platelet Aggregates as Revealed by a Patient with Hermansky-Pudlak Syndrome
2002
The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins
2011 StandoutNobel
TYPE I INTERFERONS (α/β) IN IMMUNITY AND AUTOIMMUNITY
2004 StandoutNobel
Signaling from protease-activated receptor-1 inhibits migration and invasion of breast cancer cells.
2001
Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS.
1994
Identification of Scavenger Receptor SR-BI as a High Density Lipoprotein Receptor
1996 StandoutScience
T-Independent Immune Response: New Aspects of B Cell Biology
2000 StandoutScienceNobel
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Clinical Aspects of Platelet Inhibitors and Thrombus Formation
2007
Putting polyphosphates to the test: evidence against platelet-induced activation of factor XII
2013 StandoutNobel
Protease-Activated Receptor 1 Mediates Thrombin-Dependent, Cell-Mediated Renal Inflammation in Crescentic Glomerulonephritis
2000
Lipopolysaccharide Endotoxins
2002 Standout
Heparin Blockade of Thrombin-Induced Smooth Muscle Cell Migration Involves Inhibition of Epidermal Growth Factor (EGF) Receptor Transactivation by Heparin-Binding EGF-Like Growth Factor
2000
Emerging Targets in Photopharmacology
2016 StandoutNobel
Insulin Receptor Knockout Mice
2003
Comparative Analysis of Mutant Tyrosine Kinase Chemical Rescue
2009 StandoutNobel
Activation of Platelet Function Through G Protein–Coupled Receptors
2006
Molecular physiology of reverse cholesterol transport.
1995
Protease-activated receptors 1 and 4 do not stimulate Gi signaling pathways in the absence of secreted ADP and cause human platelet aggregation independently of Gisignaling
2002
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
Protease-activated receptor 1 is the primary mediator of thrombin-stimulated platelet procoagulant activity
1999
Adhesion Mechanisms in Platelet Function
2007
Plasma elevation of stromal cell–derived factor-1 induces mobilization of mature and immature hematopoietic progenitor and stem cells
2001 StandoutNobel
Protease-Activated Receptors: Contribution to Physiology and Disease
2004
Proteinase-Activated Receptors: Transducers of Proteinase-Mediated Signaling in Inflammation and Immune Response
2004
Physiology of Microglia
2011 Standout
Proteinase-activated receptor 4 (PAR4): activation and inhibition of rat platelet aggregation by PAR4-derived peptides
2001
Works of Andrew Ching being referenced
Identification of INSL5, a New Member of the Insulin Superfamily
1999
Complementary DNA Cloning and Kinetic Characterization of a Novel Intracellular Serine Proteinase Inhibitor: Mechanism of Action with Trypsin and Factor Xa as Model Proteinases
1994
Development of the methylotrophic yeastPichia methanolica for the expression of the 65 kilodalton isoform of human glutamate decarboxylase
1998
Functional expression of human and mouse plasma phospholipid transfer protein: effect of recombinant and plasma PLTP on HDL subspecies
1995
Cloning and characterization of human protease-activated receptor 4
1998
Human thrombopoietin: gene structure, cDNA sequence, expression, and chromosomal localization.
1994
Complete cDNA encoding human phospholipid transfer protein from human endothelial cells.
1994