Citation Impact
Citing Papers
Oxidative Stress
2017 Standout
Impairment of starvation-induced and constitutive autophagy in Atg7 -deficient mice
2005 StandoutNobel
Genome-wide CRISPR screens reveal a specific ligand for the glycan-binding immune checkpoint receptor Siglec-7
2021 StandoutNobel
Protein Misfolding, Amyloid Formation, and Human Disease: A Summary of Progress Over the Last Decade
2017 Standout
MCM Proteins Are Negative Regulators of Hypoxia-Inducible Factor 1
2011 StandoutNobel
Cellular Inclusion Bodies of Mutant Huntingtin Exon 1 Obscure Small Fibrillar Aggregate Species
2012 StandoutNobel
American Society of Clinical Oncology 2007 Update of Recommendations for the Use of Tumor Markers in Breast Cancer
2007 Standout
The Thermotolerant Yeast Kluyveromyces marxianus Is a Useful Organism for Structural and Biochemical Studies of Autophagy
2015 StandoutNobel
Biomolecular condensates: organizers of cellular biochemistry
2017 Standout
The NEDD8 Pathway Is Essential for SCFβ-TrCP-mediated Ubiquitination and Processing of the NF-κB Precursor p105
2002 StandoutNobel
Gangliosides: Treatment Avenues in Neurodegenerative Disease
2019
Parkinson's disease
2021 Standout
Chronic inflammation in the etiology of disease across the life span
2019 Standout
Regulation of microRNA biogenesis
2014 Standout
The role of autophagy in neurodegenerative disease
2013 Standout
Huntington's disease
2007 Standout
The emerging role of lncRNAs in cancer
2015 Standout
Cyclin E in normal and neoplastic cell cycles
2005
C9orf72 BAC Mouse Model with Motor Deficits and Neurodegenerative Features of ALS/FTD
2016
Function and regulation of cullin–RING ubiquitin ligases
2005 Standout
Hallmarks of aging: An expanding universe
2023 Standout
NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus
2015
Pharmacology of a Central Nervous System Delivered 2′-O-Methoxyethyl–Modified Survival of Motor Neuron Splicing Oligonucleotide in Mice and Nonhuman Primates
2014
Tissue-specific regulation ofcyclin Etranscription duringDrosophila melanogasterembryogenesis
2000
Towards a therapy for Angelman syndrome by targeting a long non-coding RNA
2014 Nature
Clk post-transcriptional control denoises circadian transcription both temporally and spatially
2015 StandoutNobel
CHARMM36m: an improved force field for folded and intrinsically disordered proteins
2016 Standout
MicroRNA-92a is a circadian modulator of neuronal excitability in Drosophila
2017 StandoutNobel
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
The Drosophila Cyclin D-Cdk4 complex promotes cellular growth
2000
Mouse Models of Huntington’s Disease
2018
Decoding ALS: from genes to mechanism
2016 StandoutNature
Applications of CRISPR–Cas systems in neuroscience
2015
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Treatment of infantile-onset spinal muscular atrophy with nusinersen: a phase 2, open-label, dose-escalation study
2016 Standout
Metazoan MicroRNAs
2018 Standout
Age-Dependent Effects of apoE Reduction Using Antisense Oligonucleotides in a Model of β-amyloidosis
2017
The Hippo Signaling Pathway Coordinately Regulates Cell Proliferation and Apoptosis by Inactivating Yorkie, the Drosophila Homolog of YAP
2005 Standout
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Ubiquitin-dependent regulation of COPII coat size and function
2012 StandoutNatureNobel
Examining Polyglutamine Peptide Length: A Connection between Collapsed Conformations and Increased Aggregation
2009
The widespread regulation of microRNA biogenesis, function and decay
2010 Standout
Characterizing Light-Regulated Retinal MicroRNAs Reveals Rapid Turnover as a Common Property of Neuronal MicroRNAs
2010
Replication licensing — Origin licensing: defining the proliferative state?
2002
Acetylation Targets Mutant Huntingtin to Autophagosomes for Degradation
2009
Autophagy in Human Health and Disease
2013 Standout
The S/T-Rich Motif in the DNAJB6 Chaperone Delays Polyglutamine Aggregation and the Onset of Disease in a Mouse Model
2016
Fluorescent indicators based on BODIPY
2011 Standout
Autophagy modulation as a potential therapeutic target for diverse diseases
2012 Standout
PI3K and MEK inhibitor combinations: examining the evidence in selected tumor types
2013
Autophagy and Aging
2011 Standout
bantam Encodes a Developmentally Regulated microRNA that Controls Cell Proliferation and Regulates the Proapoptotic Gene hid in Drosophila
2003 Standout
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
Mesodermally expressed Drosophila microRNA-1 is regulated by Twist and is required in muscles during larval growth
2005 StandoutNobel
Myc-enhanced expression of Cul1 promotes ubiquitin-dependent proteolysis and cell cycle progression
2000 StandoutNobel
Drosophila microRNAs 263a/b Confer Robustness during Development by Protecting Nascent Sense Organs from Apoptosis
2010
Targeting autophagy in cancer
2017 Standout
New sensing mechanisms for design of fluorescent chemosensors emerging in recent years
2011 Standout
The PI3K Pathway in Human Disease
2017 Standout
The proteostasis network and its decline in ageing
2019
Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells
1999
Innate immune activation in neurodegenerative disease
2014
Deletion of the Cul1 gene in mice causes arrest in early embryogenesis and accumulation of cyclin E
1999
Endoreplication Cell Cycles
2001
Multiple Functions of Jab1 Are Required for Early Embryonic Development and Growth Potential in Mice
2004 StandoutNobel
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
The Neuropathology of Huntington’s Disease
2014
Mutant Huntingtin Fragments Form Oligomers in a Polyglutamine Length-dependent Manner in Vitro and in Vivo
2010
The Oscillating miRNA 959-964 Cluster Impacts Drosophila Feeding Time and Other Circadian Outputs
2012 StandoutNobel
Deletion of the Huntingtin Polyglutamine Stretch Enhances Neuronal Autophagy and Longevity in Mice
2010
SIRT1 and SIRT2: emerging targets in neurodegeneration
2013
Unmasking the roles of N- and C-terminal flanking sequences from exon 1 of huntingtin as modulators of polyglutamine aggregation
2013
Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy
2015
2019
Characterization of Target mRNA Reduction Through In Situ RNA Hybridization in Multiple Organ Systems Following Systemic Antisense Treatment in Animals
2013
The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice
2001
Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy
2017
dMyc is required for larval growth and endoreplication in Drosophila
2004
mir-276a strengthens Drosophila circadian rhythms by regulating timeless expression
2016 StandoutNobel
CSF or Serum Neurofilament Light Added to α‐Synuclein Panel Discriminates Parkinson's From Controls
2019
A Pictet-Spengler ligation for protein chemical modification
2012 StandoutNobel
Fluorescence Polarization/Anisotropy in Diagnostics and Imaging
2010
Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion
2013
The Biology of Proteostasis in Aging and Disease
2015
mTOR: a pharmacologic target for autophagy regulation
2015 Standout
Relieving Autophagy and 4EBP1 from Rapamycin Resistance
2011
The Ubiquitin-Proteasome Proteolytic Pathway: Destruction for the Sake of Construction
2002 StandoutNobel
Real-time imaging of Huntingtin aggregates diverting target search and gene transcription
2016 Nobel
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
2003 Standout
Liquid phase condensation in cell physiology and disease
2017 StandoutScience
Works of Andreas Weiss being referenced
Inducible mutant huntingtin expression in HN10 cells reproduces Huntington's disease-like neuronal dysfunction
2009
K-RAS Mutant Pancreatic Tumors Show Higher Sensitivity to MEK than to PI3K Inhibition In Vivo
2012
SIRT2 Ablation Has No Effect on Tubulin Acetylation in Brain, Cholesterol Biosynthesis or the Progression of Huntington's Disease Phenotypes In Vivo
2012
Sensitive biochemical aggregate detection reveals aggregation onset before symptom development in cellular and murine models of Huntington’s disease
2007
Development of a Method for the High‐Throughput Quantification of Cellular Proteins
2009
Proteolysis of Mutant Huntingtin Produces an Exon 1 Fragment That Accumulates as an Aggregated Protein in Neuronal Nuclei in Huntington Disease
2010
Sustained Therapeutic Reversal of Huntington's Disease by Transient Repression of Huntingtin Synthesis
2012
Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington disease
2011
Mutant huntingtin impairs immune cell migration in Huntington disease
2012
Integration-independent Transgenic Huntington Disease Fragment Mouse Models Reveal Distinct Phenotypes and Life Span in Vivo
2015
Suppression of protein aggregation by chaperone modification of high molecular weight complexes
2012
Continuous Cyclin E expression inhibits progression through endoreduplication cycles in Drosophila
1998
Reduced α‐synuclein levels in cerebrospinal fluid in P arkinson's disease are unrelated to clinical and imaging measures of disease severity
2013
Caspase-6 does not contribute to the proteolysis of mutant huntingtin in the HdhQ150 knock-in mouse model of Huntington’s disease
2012