Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Activity-Dependent Internalization of Smoothened Mediated by ß-Arrestin 2 and GRK2
2004 StandoutScienceNobel
PDGFRA Activating Mutations in Gastrointestinal Stromal Tumors
2003 StandoutScience
Multipotent CD15+ Cancer Stem Cells in Patched-1 –Deficient Mouse Medulloblastoma
2009
1 Developmental roles and clinical significance of Hedgehog signaling
2003
Identification of CD15 as a Marker for Tumor-Propagating Cells in a Mouse Model of Medulloblastoma
2009
Hallmarks of Cancer: The Next Generation
2011 Standout
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
Isolation of neural stem cells from the postnatal cerebellum
2005
Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome
1998
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
2006 StandoutNature
Cancer Invasion and the Microenvironment: Plasticity and Reciprocity
2011 Standout
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Whole Genome Amplification for Array Comparative Genomic Hybridization Using DNA Extracted from Formalin-Fixed, Paraffin-Embedded Histological Sections
2009
Involvement of Members of the Cadherin Superfamily in Cancer
2009
IDH1andIDH2Mutations in Gliomas
2009 Standout
Long survival and therapeutic responses in patient histologically disparate high-grade gliomas demonstrating chromosome 1p loss
2000
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours
2003 StandoutNature
Long non-coding RNAs in nervous system function and disease
2010
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
The patched signaling pathway in tumorigenesis and development: lessons from animal models
1999
Hedgehog and Patched in Neural Development and Disease
1998
Genetic Pathways to Primary and Secondary Glioblastoma
2007
Applying the principles of stem-cell biology to cancer
2003
Role of platelet-derived growth factors in physiology and medicine
2008 Standout
Hedgehog signalling in the mouse requires intraflagellar transport proteins
2003 StandoutNature
Cancer Metastasis: Building a Framework
2006 Standout
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
2017 Standout
Analysis of the IDH1 codon 132 mutation in brain tumors
2008
Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression
2008 Standout
Early inactivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astrocytoma
2005
The Hedgehog and Wnt signalling pathways in cancer
2001 StandoutNature
Ubiquitin ligases: cell-cycle control and cancer
2006
Medulloblastoma Growth Inhibition by Hedgehog Pathway Blockade
2002 StandoutScience
Vertebrate Smoothened functions at the primary cilium
2005 StandoutNature
Activity-Induced Expression of Common Reference Genes in Individual CNS Neurons
2001
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
2009 StandoutNature
PRC2 mediated H3K27 methylations in cellular identity and cancer
2015
Molecular and Genetic Properties of Tumors Associated with Local Immune Cytolytic Activity
2015 Standout
Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease
2001 StandoutNobel
A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA
2011 Standout
Mechanisms of Disease: genetic predictors of response to treatment in brain tumors
2007
Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme
2005
Angiogenesis in life, disease and medicine
2005 StandoutNature
Neural Stem Cells and the Origin of Gliomas
2005
Intratumoral Heterogeneity of the Epigenome
2016
Targeted Molecular Therapy of GBM
2003
On the Dependency of Cellular Protein Levels on mRNA Abundance
2016 Standout
Cause and Consequences of Genetic and Epigenetic Alterations in Human Cancer
2008
Autophagy in Human Health and Disease
2013 Standout
Identification and expansion of human colon-cancer-initiating cells
2006 StandoutNature
New players and puzzles in the Hedgehog signaling pathway
1998
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine
2000 StandoutNature
Malignant Gliomas in Adults
2008 Standout
PDGF receptors-mediators of autocrine tumor growth and regulators of tumor vasculature and stroma
2004
Control of Neuronal Precursor Proliferation in the Cerebellum by Sonic Hedgehog
1999 Standout
Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice
2000
Basic mechanisms of neurodegeneration: a critical update
2010
The t(4;22)(q12;q11) in atypical chronic myeloid leukaemia fuses BCR to PDGFRA
2002
Epigenetic modifications and human disease
2010 Standout
PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo
2008
Identification of human brain tumour initiating cells
2004 StandoutNature
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Wnt signalling in stem cells and cancer
2005 StandoutNature
Epidermal growth factor receptor and Ink4a/Arf
2002
A constitutively active epidermal growth factor receptor cooperates with disruption of G1 cell-cycle arrest pathways to induce glioma-like lesions in mice
1998 Nobel
Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice
2007 StandoutNobel
Tumour evolution inferred by single-cell sequencing
2011 StandoutNature
A restricted cell population propagates glioblastoma growth after chemotherapy
2012 StandoutNature
The TRA-1A Sex Determination Protein of C. elegans Regulates Sexually Dimorphic Cell Deaths by Repressing the egl-1 Cell Death Activator Gene
1999 StandoutNobel
The Presynaptic Active Zone Protein RIM1α Is Critical for Normal Learning and Memory
2004 StandoutNobel
Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib
2004 Standout
Peptidic degron in EID1 is recognized by an SCF E3 ligase complex containing the orphan F-box protein FBXO21
2015 StandoutNobel
Phase II Study of Imatinib in Patients With Recurrent Gliomas of Various Histologies: A European Organisation for Research and Treatment of Cancer Brain Tumor Group Study
2008
Gene Regulatory Networks and the Evolution of Animal Body Plans
2006 StandoutScience
Patched1 Regulates Hedgehog Signaling at the Primary Cilium
2007 StandoutScience
Hedgehog Signaling and Human Disease
2002
Gene expression profiling of low-grade diffuse astrocytomas by cDNA arrays.
2000
The normal patched allele is expressed in medulloblastomas from mice with heterozygous germ-line mutation of patched.
2000
Brain Tumor Stem Cells: Bringing Order to the Chaos of Brain Cancer
2008
Tumor-Infiltrating Lymphocytes in Glioblastoma Are Associated with Specific Genomic Alterations and Related to Transcriptional Class
2013
Phase II Trial of Gefitinib in Recurrent Glioblastoma
2003
The Developmental Biology of Brain Tumors
2001
Normalization of Tumor Vasculature: An Emerging Concept in Antiangiogenic Therapy
2005 StandoutScience
Genetic Pathways to Glioblastoma
2004
Deletions of AXIN1, a component of the WNT/wingless pathway, in sporadic medulloblastomas.
2001
The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis
2001 Standout
HIF-1 and human disease: one highly involved factor
2000 StandoutNobel
Evidence that haploinsufficiency ofPtch leads to medulloblastoma in mice
2000
Sonic hedgehog Promotes G1Cyclin Expression and Sustained Cell Cycle Progression in Mammalian Neuronal Precursors
2000
Malignant glioma: genetics and biology of a grave matter
2001
Simultaneous Blockade of Platelet-Derived Growth Factor-Receptor and Epidermal Growth Factor-Receptor Signaling and Systemic Administration of Paclitaxel as Therapy for Human Prostate Cancer Metastasis in Bone of Nude Mice
2004
Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor
1999 Standout
Works of Andreas Waha being referenced
Epigenetic Silencing of the Protocadherin Family Member PCDH-γ-All in Astrocytomas
2005
A Rapid and Sensitive Protocol for Competitive Reverse Transcriptase (cRT) PCR Analysis of Cellular Genes
1998
Amplification of the cyclin-dependent kinase 4 ( CDK4 ) gene is associated with high cdk4 protein levels in glioblastoma multiforme
1996
Different methylation of the TNF-alpha promoter in cortex and substantia nigra: Implications for selective neuronal vulnerability
2008
Variable Imprinting of H19 and IGF2 in Fetal Cerebellum and Medulloblastoma
1996
A Polymerase Chain Reaction-based Assay for the Rapid Detection of Gene Amplification in Human Tumors
1996
Optimization of Quantitative MGMT Promoter Methylation Analysis Using Pyrosequencing and Combined Bisulfite Restriction Analysis
2007
Association of EGFR Gene Amplification and CDKN2 (p16/MTS1) Gene Deletion in Glioblastoma Multiforme
1997
Loci associated with malignant progression in astrocytomas: a candidate on chromosome 19q.
1994
Association of loss of heterozygosity on chromosome 17p with high platelet-derived growth factor alpha receptor expression in human malignant gliomas.
1996
Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched.
1997
H3F3A K27M Mutation in Pediatric CNS Tumors
2013
Molecular genetic analysis of giant cell glioblastomas.
1997
The epidermal growth factor receptor in glioblastoma: genomic amplification, protein expression, and patient survival data in a therapeutic trial.
1995
Elevated Expression of Wnt Antagonists Is a Common Event in Hepatoblastomas
2005