Citation Impact
Citing Papers
Activation of the p62‐Keap1‐NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells
2015 Standout
Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages
2014
C-ferroptosis is an iron-dependent form of regulated cell death in cyanobacteria
2021
Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis
2014
Ferroptosis regulation by the NGLY1/NFE2L1 pathway
2022 StandoutNobel
PUMA amplifies necroptosis signaling by activating cytosolic DNA sensors
2018
Pyroptosis versus necroptosis: similarities, differences, and crosstalk
2018
Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis
2014 Standout
Cutting Edge: RIPK1 Kinase Inactive Mice Are Viable and Protected from TNF-Induced Necroptosis In Vivo
2014
Extrinsic and intrinsic apoptosis activate pannexin‐1 to drive NLRP 3 inflammasome assembly
2019
Cellular IAP proteins and LUBAC differentially regulate necrosome-associated RIP1 ubiquitination
2015
A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis
2019
miR-137 regulates ferroptosis by targeting glutamine transporter SLC1A5 in melanoma
2018
miR-212-5p attenuates ferroptotic neuronal death after traumatic brain injury by targeting Ptgs2
2019
An outline of necrosome triggers
2016
Target-conditioned diffusion generates potent TNFR superfamily antagonists and agonists
2024 StandoutScienceNobel
Brain mitochondrial iron accumulates in Huntington's disease, mediates mitochondrial dysfunction, and can be removed pharmacologically
2018
Ferroptosis: past, present and future
2020 Standout
Embryonal erythropoiesis and aging exploit ferroptosis
2021
Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells
2016
Mechanisms of ferroptosis
2016
An Inducible Retroviral Expression System for Tandem Affinity Purification Mass-Spectrometry-Based Proteomics Identifies Mixed Lineage Kinase Domain-like Protein (MLKL) as an Heat Shock Protein 90 (HSP90) Client
2016
Transferrin Receptor Is a Specific Ferroptosis Marker
2020
Entosis Is Induced by Glucose Starvation
2017
Nck adapter proteins: functional versatility in T cells
2009
Cancer therapy in the necroptosis era
2016
Cysteine Dioxygenase 1 Mediates Erastin-Induced Ferroptosis in Human Gastric Cancer Cells
2017
Activation of the reverse transsulfuration pathway through NRF2/CBS confers erastin-induced ferroptosis resistance
2019
Ferroptotic pores induce Ca2+ fluxes and ESCRT-III activation to modulate cell death kinetics
2020
Mlkl knockout mice demonstrate the indispensable role of Mlkl in necroptosis
2013
Ferroptosis: molecular mechanisms and health implications
2020 Standout
Necrostatin-1 analogues: critical issues on the specificity, activity and in vivo use in experimental disease models
2012
Receptor-interacting protein kinase 3 deficiency inhibits immune cell infiltration and attenuates organ injury in sepsis
2014
Genome-wide Analysis of Host-Plasmodium yoelii Interactions Reveals Regulators of the Type I Interferon Response
2015
Spermidine rescues proximal tubular cells from oxidative stress and necrosis after ischemic acute kidney injury
2017
Dietary Lipids Induce Ferroptosis in Caenorhabditiselegans and Human Cancer Cells
2020
HSPB1 as a novel regulator of ferroptotic cancer cell death
2015
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death
2007
Ferroptosis: Death by Lipid Peroxidation
2015 Standout
Ferroptosis is controlled by the coordinated transcriptional regulation of glutathione and labile iron metabolism by the transcription factor BACH1
2019
Characterization of a rat monoclonal antibody raised against ferroptotic cells
2020
Necroptosis and its role in inflammation
2015 StandoutNature
Reactive oxygen species regulate Smac mimetic/TNFα-induced necroptotic signaling and cell death
2015
Unsolved mysteries: How does lipid peroxidation cause ferroptosis?
2018
A compendium of kinetic modulatory profiles identifies ferroptosis regulators
2021
Prominin2 Drives Ferroptosis Resistance by Stimulating Iron Export
2019
RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis
2018
Glutathione peroxidase 4 participates in secondary brain injury through mediating ferroptosis in a rat model of intracerebral hemorrhage
2018
MESH1 is a cytosolic NADPH phosphatase that regulates ferroptosis
2020
Murine Double Minute-2 Prevents p53-Overactivation-Related Cell Death (Podoptosis) of Podocytes
2014
Distinct roles of RIP1–RIP3 hetero- and RIP3–RIP3 homo-interaction in mediating necroptosis
2014
The biology and management of non-small cell lung cancer
2018 StandoutNature
Nuclear RIPK3 and MLKL contribute to cytosolic necrosome formation and necroptosis
2018
Death by TNF: a road to inflammation
2022
Targeting Ferroptosis to Iron Out Cancer
2019 Standout
Depletion of RIPK3 or MLKL blocks TNF-driven necroptosis and switches towards a delayed RIPK1 kinase-dependent apoptosis
2014
The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity
2017
Complex Pathologic Roles of RIPK1 and RIPK3: Moving Beyond Necroptosis
2017
The chemical basis of ferroptosis
2019
Caveolin-1 dictates ferroptosis in the execution of acute immune-mediated hepatic damage by attenuating nitrogen stress
2019
Ferroptosis, a newly characterized form of cell death in Parkinson's disease that is regulated by PKC
2016
The Coming Decade of Cell Death Research: Five Riddles
2019
Hallmarks of aging: An expanding universe
2023 Standout
Non-canonical Glutamate-Cysteine Ligase Activity Protects against Ferroptosis
2020
Ferroptosis at the crossroads of cancer-acquired drug resistance and immune evasion
2019
Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications
2022 Standout
MDM2 and MDMX promote ferroptosis by PPARα-mediated lipid remodeling
2020
Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis
2016
Necroptosis and neutrophil-associated disorders
2018
Diverse compounds from pleuromutilin lead to a thioredoxin inhibitor and inducer of ferroptosis
2019
Ferroptosis and necroinflammation, a yet poorly explored link
2018
Protective Roles for Caspase-8 and cFLIP in Adult Homeostasis
2013
Comparing the effects of different cell death programs in tumor progression and immunotherapy
2018
The molecular machinery of regulated cell death
2019 Standout
The retinoblastoma (Rb) protein regulates ferroptosis induced by sorafenib in human hepatocellular carcinoma cells
2014
Absence of receptor interacting protein kinase 3 prevents ethanol-induced liver injury
2012
Identification of ACSL4 as a biomarker and contributor of ferroptosis
2016
Ferroptosis Inhibition: Mechanisms and Opportunities
2017
Mechanism of splenic cell death and host mortality in a Plasmodium yoelii malaria model
2017
Ferroptosis is a type of autophagy-dependent cell death
2019
Identification of PRDX6 as a regulator of ferroptosis
2019
Dihydrolipoamide dehydrogenase regulates cystine deprivation-induced ferroptosis in head and neck cancer
2020
Activation of Glutathione Peroxidase 4 as a Novel Anti-inflammatory Strategy
2018
Striking while the iron is hot: Iron metabolism and ferroptosis in neurodegeneration
2018
Tau-mediated iron export prevents ferroptotic damage after ischemic stroke
2017
Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation
2015
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
Natural Product Kongensin A is a Non-Canonical HSP90 Inhibitor that Blocks RIP3-dependent Necroptosis
2016
Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasis
2016
NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis
2015
Beyond DPPH: Use of Fluorescence-Enabled Inhibited Autoxidation to Predict Oxidative Cell Death Rescue
2019
Breakdown of an Ironclad Defense System: The Critical Role of NRF2 in Mediating Ferroptosis
2020
Blockade of ALK4/5 signaling suppresses cadmium- and erastin-induced cell death in renal proximal tubular epithelial cells via distinct signaling mechanisms
2019
Emerging Mechanisms and Disease Relevance of Ferroptosis
2020
Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis
2016
Exogenous Monounsaturated Fatty Acids Promote a Ferroptosis-Resistant Cell State
2019
Systematic Quantification of Population Cell Death Kinetics in Mammalian Cells
2017
Necroptosis: The Release of Damage-Associated Molecular Patterns and Its Physiological Relevance
2013
Regulation of RIPK3- and RHIM-dependent Necroptosis by the Proteasome
2016
The role of iron and reactive oxygen species in cell death
2013 Standout
A long-awaited merger of the pathways mediating host defence and programmed cell death
2014
Cell-Line Selectivity Improves the Predictive Power of Pharmacogenomic Analyses and Helps Identify NADPH as Biomarker for Ferroptosis Sensitivity
2016
To eat or not to eat — the metabolic flavor of ferroptosis
2017
Autophagy and Ferroptosis—What Is the Connection?
2017
Glutaminolysis and Transferrin Regulate Ferroptosis
2015 Standout
MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation
2017
Protective Effects of Dexmedetomidine on Sepsis-Induced Vascular Leakage by Alleviating Ferroptosis via Regulating Metabolic Reprogramming
2021
Neutrophil extracellular traps in immunity and disease
2017 Standout
The diverse role of RIP kinases in necroptosis and inflammation
2015
HMGB1 in health and disease
2014
Acute kidney injury
2021 Standout
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death
2017
The role of glycine in regulated cell death
2016
Selenium: Tracing Another Essential Element of Ferroptotic Cell Death
2020
Glutathione peroxidase 4–regulated neutrophil ferroptosis induces systemic autoimmunity
2021
NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis
2019 Standout
ESCRT-III–dependent membrane repair blocks ferroptosis
2019
Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells
2015
Role of TNF–TNF Receptor 2 Signal in Regulatory T Cells and Its Therapeutic Implications
2018
Phase transitions in the assembly of multivalent signalling proteins
2012 StandoutNature
Ferroptosis is an autophagic cell death process
2016
Vascular Signaling in Allogenic Solid Organ Transplantation – The Role of Endothelial Cells
2020
MLKL Compromises Plasma Membrane Integrity by Binding to Phosphatidylinositol Phosphates
2014
TAK1 regulates caspase 8 activation and necroptotic signaling via multiple cell death checkpoints
2016
Necroptosis in development and diseases
2018
The Hippo Pathway Effector TAZ Regulates Ferroptosis in Renal Cell Carcinoma
2019
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
2015 StandoutNature
RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis
2014 Nature
Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease
2015
FANCD2 protects against bone marrow injury from ferroptosis
2016
Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion
2019
Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis
2021
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
2016 StandoutNature
Resolution of inflammation: a new therapeutic frontier
2016
p53 in survival, death and metabolic health: a lifeguard with a licence to kill
2015
Regulated necrosis: disease relevance and therapeutic opportunities
2016
Oxytosis/Ferroptosis—(Re-) Emerging Roles for Oxidative Stress-Dependent Non-apoptotic Cell Death in Diseases of the Central Nervous System
2018
CYLD Proteolysis Protects Macrophages from TNF-Mediated Auto-necroptosis Induced by LPS and Licensed by Type I IFN
2016
Ferroptosis: process and function
2016 Standout
RIPK1 Blocks Early Postnatal Lethality Mediated by Caspase-8 and RIPK3
2014
Necroptosis in development, inflammation and disease
2016
FOXP3+ regulatory T cells in the human immune system
2010 StandoutNobel
Oxidative Damage and Antioxidant Defense in Ferroptosis
2020
The development of the concept of ferroptosis
2018
Ferroptosis drives photoreceptor degeneration in mice with defects in all-trans-retinal clearance
2021
Developmental checkpoints guarded by regulated necrosis
2016
Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN Production
2014
Mitochondria as multifaceted regulators of cell death
2019 Standout
ROS Are Good
2016 Standout
Caspases Connect Cell-Death Signaling to Organismal Homeostasis
2016
CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3
2016
Ppm1b negatively regulates necroptosis through dephosphorylating Rip3
2015
The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
2019 StandoutNature
Ferroptosis: mechanisms, biology and role in disease
2021 Standout
The tumor suppressor protein p53 and the ferroptosis network
2018
Metabolic determinants of cancer cell sensitivity to canonical ferroptosis inducers
2020
Therapeutic exploitation of necroptosis for cancer therapy
2014
Necroptosis: an alternative cell death program defending against cancer
2016
miRNA-17-92 protects endothelial cells from erastin-induced ferroptosis through targeting the A20-ACSL4 axis
2019
Artemisinin compounds sensitize cancer cells to ferroptosis by regulating iron homeostasis
2019
Gasdermins: Effectors of Pyroptosis
2017 Standout
Necroptosis and ferroptosis are alternative cell death pathways that operate in acute kidney failure
2017
Hallmarks of Health
2020
MLKL Requires the Inositol Phosphate Code to Execute Necroptosis
2018
A Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of Ferroptosis
2016
Pathophysiological role of different tubular epithelial cell death modes in acute kidney injury
2015
RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome
2017
Kinome screen of ferroptosis reveals a novel role of ATM in regulating iron metabolism
2019
The ubiquitin-modifying enzyme A20 restricts ubiquitination of the kinase RIPK3 and protects cells from necroptosis
2015
Combinatorial Strategies for the Induction of Immunogenic Cell Death
2015
Antiferroptotic activity of non-oxidative dopamine
2016
CISD1 inhibits ferroptosis by protection against mitochondrial lipid peroxidation
2016
Oxidative stress-mediated HMGB1 biology
2015
Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition
2017 Nature
Imidazole Ketone Erastin Induces Ferroptosis and Slows Tumor Growth in a Mouse Lymphoma Model
2019
Ferroptosis as a Novel Therapeutic Target for Friedreich’s Ataxia
2019
Selective Targeting of TNF Receptors as a Novel Therapeutic Approach
2020
Energy-stress-mediated AMPK activation inhibits ferroptosis
2020
RIPK3-Mediated Necroptosis Regulates Cardiac Allograft Rejection
2014
NF-κB, inflammation, immunity and cancer: coming of age
2018 Standout
Human Monocytes Engage an Alternative Inflammasome Pathway
2016
Dispensable roles of Gsdmd and Ripk3 in sustaining IL-1β production and chronic inflammation in Th17-mediated autoimmune arthritis
2021 StandoutNobel
Programmed Necrosis and Disease:We interrupt your regular programming to bring you necroinflammation
2018
Role of Mitochondria in Ferroptosis
2018 Standout
Copper-Binding Small Molecule Induces Oxidative Stress and Cell-Cycle Arrest in Glioblastoma-Patient-Derived Cells
2018
Iron Metabolism in Ferroptosis
2020
Apoptotic Caspases Prevent the Induction of Type I Interferons by Mitochondrial DNA
2014
Single-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture
2018
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
2017 StandoutNature
GPx4, Lipid Peroxidation, and Cell Death: Discoveries, Rediscoveries, and Open Issues
2017
Intracellular Nucleic Acid Sensing Triggers Necroptosis through Synergistic Type I IFN and TNF Signaling
2018
ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation
2018 Science
RTP4 inhibits IFN-I response and enhances experimental cerebral malaria and neuropathology
2020 StandoutNobel
GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling
2019
Necroptosis: Mechanisms and Relevance to Disease
2016
CuII(atsm) inhibits ferroptosis: Implications for treatment of neurodegenerative disease
2019
Control of Life-or-Death Decisions by RIP1 Kinase
2013
Inflammatory outcomes of apoptosis, necrosis and necroptosis
2014
Sialyl Lewis x (CD15s) identifies highly differentiated and most suppressive FOXP3 high regulatory T cells in humans
2015 StandoutNobel
The cell's dilemma, or the story of cell death: an entertainment in three acts
2016
Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases
2017 Standout
Iron- and Reactive Oxygen Species-Dependent Ferroptotic Cell Death in Rice-Magnaporthe oryzae Interactions
2018
Emerging Opportunities To Manipulate Metal Trafficking for Therapeutic Benefit
2019
Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
2016 Standout
Five-Membered Ring Peroxide Selectively Initiates Ferroptosis in Cancer Cells
2016
Programmed Necrosis in the Cross Talk of Cell Death and Inflammation
2014
Metabolic control of cell death
2014 Science
Pain regulation by non-neuronal cells and inflammation
2016 StandoutScience
Hepatic transferrin plays a role in systemic iron homeostasis and liver ferroptosis
2020
Pore-forming activity and structural autoinhibition of the gasdermin family
2016 StandoutNature
Heat stress induces ferroptosis-like cell death in plants
2017
Necroptosis in health and diseases
2014
Tryparedoxin peroxidase-deficiency commits trypanosomes to ferroptosis-type cell death
2018
Inhibition of ferroptosis attenuates tissue damage and improves long‐term outcomes after traumatic brain injury in mice
2018
The Hallmarks of Ferroptosis
2018
Iron and cancer: recent insights
2016
Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium
2017
The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents
2015
Excess heme upregulates heme oxygenase 1 and promotes cardiac ferroptosis in mice with sickle cell disease
2021
Diacylfuroxans Are Masked Nitrile Oxides That Inhibit GPX4 Covalently
2019
Cutting Edge: In Contrast to Effector T Cells, CD4+CD25+FoxP3+ Regulatory T Cells Are Highly Susceptible to CD95 Ligand- but Not to TCR-Mediated Cell Death
2005
Cytokine Storm
2020 Standout
Activation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell death
2014
Molecular crosstalk between ferroptosis and apoptosis: emerging role of ER stress-induced p53-independent PUMA expression
2017
On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death
2017 Standout
Spermidine in health and disease
2018 StandoutScience
Switching Apoptosis to Ferroptosis: Metal–Organic Network for High-Efficiency Anticancer Therapy
2016
Ferroptosis: machinery and regulation
2020
Recent Progress in Ferroptosis Inducers for Cancer Therapy
2019
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death
2015
Caspase‐11: arming the guards against bacterial infection
2015
Metabolic reprogramming and cancer progression
2020 StandoutScience
Quantitative Profiling of Protein Carbonylations in Ferroptosis by an Aniline-Derived Probe
2018
Autophagy pathway: Cellular and molecular mechanisms
2017 Standout
PLA2G6 guards placental trophoblasts against ferroptotic injury
2020
Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature
2019 StandoutNobel
An essential role for functional lysosomes in ferroptosis of cancer cells
2016
To the edge of cell death and back
2018
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
The 5-Lipoxygenase Inhibitor Zileuton Confers Neuroprotection against Glutamate Oxidative Damage by Inhibiting Ferroptosis
2015
Caspase-8 induces cleavage of gasdermin D to elicit pyroptosis during Yersinia infection
2018
Cell–cell contacts protect against t-BuOOH-induced cellular damage and ferroptosis in vitro
2019
Autophagy promotes ferroptosis by degradation of ferritin
2016 Standout
Protective effects of the mechanistic target of rapamycin against excess iron and ferroptosis in cardiomyocytes
2017
Chaperone-mediated autophagy is involved in the execution of ferroptosis
2019
A new kind of cell suicide: mechanisms and functions of programmed necrosis
2014
RIPK1 and NF-κB signaling in dying cells determines cross-priming of CD8 + T cells
2015 Science
Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells
2015
A major role for ferroptosis in Mycobacterium tuberculosis–induced cell death and tissue necrosis
2019
Resolving the Role of Lipoxygenases in the Initiation and Execution of Ferroptosis
2018
Heme oxygenase-1 mitigates ferroptosis in renal proximal tubule cells
2017
Caspase‐8: regulating life and death
2017 Standout
Differential cell death decisions in the testis: evidence for an exclusive window of ferroptosis in round spermatids
2019
Works of Andreas Linkermann being referenced
TWEAK and RIPK1 mediate a second wave of cell death during AKI
2018
Necroptosis controls NET generation and mediates complement activation, endothelial damage, and autoimmune vasculitis
2017
RIPK3-Mediated Necroptosis Promotes Donor Kidney Inflammatory Injury and Reduces Allograft Survival
2013
Widespread Mitochondrial Depletion via Mitophagy Does Not Compromise Necroptosis
2013
A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis
2015
CD95 ligand - death factor and costimulatory molecule?
2003
Necroinflammation in Kidney Disease
2015
Regulated cell death and inflammation: an auto-amplification loop causes organ failure
2014
Regulated Cell Death in AKI
2014
ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences
2017
TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death
2013
Excess sphingomyelin disturbs ATG9A trafficking and autophagosome closure
2016
TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation
2018
Molecular mechanisms of regulated necrosis
2014
HLA class II antibodies induce necrotic cell death in human endothelial cells via a lysosomal membrane permeabilization-mediated pathway
2019
The RIP1-Kinase Inhibitor Necrostatin-1 Prevents Osmotic Nephrosis and Contrast-Induced AKI in Mice
2013
Necroptosis
2014
Effective Blockage of Both the Extrinsic and Intrinsic Pathways of Apoptosis in Mice by TAT-crmA
2010
Regulated necrosis: the expanding network of non-apoptotic cell death pathways
2014
Dichotomy between RIP1- and RIP3-Mediated Necroptosis in Tumor Necrosis Factor-α-Induced Shock
2012
Ca2+ signals, cell membrane disintegration, and activation of TMEM16F during necroptosis
2016
Ferroptosis-inducing agents compromise in vitro human islet viability and function
2018
Generation of small molecules to interfere with regulated necrosis
2016
Considering Fas ligand as a target for therapy
2005
Ferroptosis and Necroptosis in the Kidney
2020
An Overview of Pathways of Regulated Necrosis in Acute Kidney Injury
2016
Role of necroptosis in the pathogenesis of solid organ injury
2015
Rip1 (Receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury
2012
The adaptor protein Nck interacts with Fas ligand: Guiding the death factor to the cytotoxic immunological synapse
2006
The in vivo evidence for regulated necrosis
2017
Origin and Consequences of Necroinflammation
2018
Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid–Induced AKI
2016
Two independent pathways of regulated necrosis mediate ischemia–reperfusion injury
2013
The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis
2016
RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction
2014
Cell Death Pathways Drive Necroinflammation during Acute Kidney Injury
2018
The pathological features of regulated necrosis
2019
Ferroptosis as a target for protection against cardiomyopathy
2019 Standout
Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models
2014
Loss of Cardiac Ferritin H Facilitates Cardiomyopathy via Slc7a11-Mediated Ferroptosis
2020
Anti-ferroptotic mechanism of IL4i1-mediated amino acid metabolism
2021
PMA and crystal‐induced neutrophil extracellular trap formation involves RIPK1‐RIPK3‐MLKL signaling
2015
Caspase-8–dependent gasdermin D cleavage promotes antimicrobial defense but confers susceptibility to TNF-induced lethality
2020
Exquisite sensitivity of adrenocortical carcinomas to induction of ferroptosis
2019 Nobel
Determination of the Subcellular Localization and Mechanism of Action of Ferrostatins in Suppressing Ferroptosis
2018