Citation Impact
Citing Papers
Single-Molecule Imaging of an in Vitro -Evolved RNA Aptamer Reveals Homogeneous Ligand Binding Kinetics
2009 StandoutNobel
A Genomewide Search for Ribozymes Reveals an HDV-Like Sequence in the Human CPEB3 Gene
2006 StandoutScienceNobel
A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads
2012 StandoutScience
MCM Proteins Are Negative Regulators of Hypoxia-Inducible Factor 1
2011 StandoutNobel
Structural Insights into the Evolution of a Non-Biological Protein: Importance of Surface Residues in Protein Fold Optimization
2007 StandoutNobel
Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes
2013 Standout
Relative Unidirectional Translation in an Artificial Molecular Assembly Fueled by Light
2013 StandoutNobel
Protein-dependent ribozymes report molecular interactions in real time
2002
A Ribozyme for the Aldol Reaction
2005
Toward Automated Nucleic Acid Enzyme Selection
2001
Construction, Stability, and Activity of Multivalent Circular Anticoagulant Aptamers
2004
A general approach for the use of oligonucleotide effectors to regulate the catalysis of RNA-cleaving ribozymes and DNAzymes
2002
Functional proteins from a random-sequence library
2001 StandoutNatureNobel
In vitro selection of signaling aptamers
2000
An artificial molecular pump
2015 StandoutNobel
Highly enantioselective DNA-based catalysis
2006 StandoutNobel
Single-stranded DNA aptamers that bind differentiated but not parental cells: subtractive systematic evolution of ligands by exponential enrichment
2003
Catalytic Molecular Beacons
2001
Conformational Control of Energy Transfer: A Mechanism for Biocompatible Nanocrystal‐Based Sensors
2012 StandoutNobel
Asymmetric Catalysis by Chiral Hydrogen‐Bond Donors
2006 Standout
Enzymatic Primer-Extension with Glycerol-Nucleoside Triphosphates on DNA Templates
2009 StandoutNobel
Rapid kinetic characterization of hammerhead ribozymes by real-time monitoring of fluorescence resonance energy transfer (FRET)
1999
Iterative In Situ Click Chemistry Creates Antibody‐like Protein‐Capture Agents
2009 StandoutNobel
Displacement of protein-bound aptamers with small molecules screened by fluorescence polarization
2008
Electrospray ionization of nucleic acid aptamer/small molecule complexes for screening aptamer selectivity
2005
Widely Applicable Pd‐Catalyzed trans‐Selective Monoalkylation of Unactivated 1,1‐Dichloro‐1‐alkenes and Pd‐Catalyzed Second Substitution for the Selective Synthesis of E or Z Trisubstituted Alkenes
2005 StandoutNobel
Aptamer Displacement Identifies Alternative Small-Molecule Target Sites that Escape Viral Resistance
2007
Screening for engineered neomycin riboswitches that control translation initiation
2007
A novel mode of regulation of an RNA-cleaving DNAzyme by effectors that bind to both enzyme and substrate
2001
DNA‐Based Asymmetric Catalysis
2005 StandoutNobel
Novel RNA catalysts for the Michael reaction
2001
In Vitro Selection of Structure‐Switching Signaling Aptamers
2005
Aptamer Database
2003
Engineered allosteric ribozymes as biosensor components
2002
Aptamers as tools for target validation
2005
The Diels-Alder Reaction in Total Synthesis
2002 Standout
A General Strategy for Effector-mediated Control of RNA-cleaving Ribozymes and DNA Enzymes
2002
Peptidyl-transferase ribozymes: trans reactions, structural characterization and ribosomal RNA-like features
1998 Nobel
The tyranny of adenosine recognition among RNA aptamers to coenzyme A
2003
Novel methods for biocatalyst screening
2001
Aptamers: molecular tools for analytical applications
2007
Integrated Nanoparticle–Biomolecule Hybrid Systems: Synthesis, Properties, and Applications
2004 Standout
Constructing high complexity synthetic libraries of long ORFs using In Vitro selection
2000 StandoutNobel
In Vitro Selection of Nucleic Acid Enzymes
1999
Nucleic Acid Based Molecular Devices
2011
Pumps, paradoxes and ploughshares: mechanism of the MCM2–7 DNA helicase
2005
In vitro selection of allosteric ribozymes: theory and experimental validation11Edited by R. Huber
2001
The crystal structure of the Thermus aquaticus DnaB helicase monomer
2007 StandoutNobel
Synthesizing life
2001 StandoutNatureNobel
Controlling Protein Activity with Ligand-Regulated RNA Aptamers
2002
Fluorescent DNAzyme Biosensors for Metal Ions Based on Catalytic Molecular Beacons
2006
Enantioselective Friedel–Crafts Reactions in Water Using a DNA‐Based Catalyst
2009 StandoutNobel
A deoxyribozyme-based molecular automaton
2003
The chemical repertoire of natural ribozymes
2002 StandoutNatureNobel
A small catalytic RNA motif with Diels-Alderase activity
1999
Nanoparticles, Proteins, and Nucleic Acids: Biotechnology Meets Materials Science
2001 Standout
Merging homogeneous catalysis with biocatalysis; papain as hydrogenation catalyst
2005 StandoutNobel
SELEX for Tubulin Affords Specific T-Rich DNA Aptamers
2001
A biosensor for theophylline based on fluorescence detection of ligand-induced hammerhead ribozyme cleavage
2002
Rube Goldberg goes (ribo)nuclear? Molecular switches and sensors made from RNA
2003
A Simple Fluorescent Biosensor for Theophylline Based on its RNA Aptamer
2006
A novel strategy for selection of allosteric ribozymes yields RiboReporterTM sensors for caffeine and aspartame
2004
The antiquity of RNA-based evolution
2002 Nature
Structure and Dynamics of a Processive Brownian Motor: The Translating Ribosome
2010 StandoutNobel
A Novel, Modification-Dependent ATP-Binding Aptamer Selected from an RNA Library Incorporating a Cationic Functionality
2003 StandoutNobel
Kinetic Analysis of an Efficient DNA-Dependent TNA Polymerase
2005 StandoutNobel
Functional Nucleic Acid Sensors
2009 Standout
A Small Aptamer with Strong and Specific Recognition of the Triphosphate of ATP
2004 StandoutNobel
Selection of Smart Aptamers by Methods of Kinetic Capillary Electrophoresis
2006
Covalent Schiff Base Catalysis and Turnover by a DNAzyme: A M2+-Independent AP-Endonuclease Mimic
2004
Isolation of high-affinity GTP aptamers from partially structured RNA libraries
2002 StandoutNobel
In Vitro Selection of a Ligase Ribozyme Carrying Alkylamino Groups in the Side Chains
2000
Aptamer affinity chromatography:
1999
Polymer/Silica Nanocomposites: Preparation, Characterization, Properties, and Applications
2008 Standout
Flexizymes: Their Evolutionary History and the Origin of Catalytic Function
2011
Intelligent Colloidal Hybrids via Reversible pH-Induced Complexation of Polyelectrolyte and Silica Nanoparticles
2003
Sequence-Specific Detection of MicroRNAs by Signal-Amplifying Ribozymes
2003
DNA Polymerase-Mediated DNA Synthesis on a TNA Template
2002 StandoutNobel
Functional information and the emergence of biocomplexity
2007 StandoutNobel
Aptamers Selected for Higher-Affinity Binding Are Not More Specific for the Target Ligand
2006 StandoutNobel
The First Total Synthesis of (+)-Ratjadone
2001
Single-Molecule RNA Science
2005
The Structural Basis of Ribosome Activity in Peptide Bond Synthesis
2000 StandoutScienceNobel
Dynamic Combinatorial Chemistry
2006 Standout
FRET Study of a Trifluorophore-Labeled DNAzyme
2002
Electronic ‘Off‐On’ Molecular Switch for Rapid Detection of Thrombin
2006
Nucleic Acid AptamersFrom Selection in Vitro to Applications in Vivo
2000
Cell Cycle Regulation of DNA Replication
2007
In Vitro Selection of Aptamers with Affinity for Neuropeptide Y Using Capillary Electrophoresis
2005
Informational Complexity and Functional Activity of RNA Structures
2004 StandoutNobel
Artificial Molecular Machines
2015 Standout
Specific, rapid synthesis of Phe-RNA by RNA
1999
Recent Advances in Efficient and Selective Synthesis of Di-, Tri-, and Tetrasubstituted Alkenes via Pd-Catalyzed Alkenylation−Carbonyl Olefination Synergy
2008 StandoutNobel
Functional Aptamers and Aptazymes in Biotechnology, Diagnostics, and Therapy
2007
Expanding the Substrate Repertoire of a DNA Polymerase by Directed Evolution
2004
Aptamer affinity chromatography: combinatorial chemistry applied to protein purification.
1999
Enzymatic synthesis of DNA on glycerol nucleic acid templates without stable duplex formation between product and template
2007 StandoutNobel
Activatable Photosensitizers for Imaging and Therapy
2010 Standout
Electrogenerated Chemiluminescence and Its Biorelated Applications
2008 Standout
In Vitro Selection of Functional Nucleic Acids
1999 StandoutNobel
Synthetic Riboswitches That Induce Gene Expression in Diverse Bacterial Species
2010 StandoutNobel
Triggered amplification by hybridization chain reaction
2004 Standout
The Emergence of Competition Between Model Protocells
2004 StandoutScienceNobel
Behavior of Polycatalytic Assemblies in a Substrate-Displaying Matrix
2006
Constructing an RNA world
1999
The bacterial replicative helicase DnaB evolved from a RecA duplication.
2000
TNA Synthesis by DNA Polymerases
2003 StandoutNobel
Impact of scaffold rigidity on the design and evolution of an artificial Diels-Alderase
2014 StandoutNobel
Works of Andreas Jenne being referenced
Aptamers and aptazymes: accelerating small molecule drug discovery.
2002
Rapid identification and characterization of hammerhead-ribozyme inhibitors using fluorescence-based technology
2001
A novel ribozyme with ester transferase activity
1998
Real-Time Characterization of Ribozymes by Fluorecence Resonance Energy Transfer (FRET)
1999
Synthesis, incorporation efficiency, and stability of disulfide bridged functional groups at RNA 5′-ends
2000
Aptamers in Research and Drug Development
2004
An Allosteric Ribozyme Regulated by Doxycyline
2000
An Allosteric Ribozyme Regulated by Doxycyline This work was supported by Aventis Gencell and by a grant from the Volkswagen Foundation (Priority program “conformational control”) to M.F. We thank M. Blind, G. Mayer, D. Proske, and G. Sengle (Universität Bonn) for helpful discussions as well as J. Crouzet, J. F. Mayaux, and M. Finer (Aventis Gencell) for support.
2001
Oligonucleotide libraries - variatio delectat
1998
Ein durch Doxycyclin reguliertes allosterisches Ribozym
2000
Ein durch Doxycyclin reguliertes allosterisches Ribozym
2001
Disruption of the Streptavidin Interaction with Biotinylated Nucleic Acid Probes by 2-Mercaptoethanol
1999
Two Regions of Simian Virus 40 T Antigen Determine Cooperativity of Double-Hexamer Assembly on the Viral Origin of DNA Replication and Promote Hexamer Interactions during Bidirectional Origin DNA Unwinding
1999