Citation Impact
Citing Papers
Complement and microglia mediate early synapse loss in Alzheimer mouse models
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Decreased Clearance of CNS β-Amyloid in Alzheimer’s Disease
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MARK/PAR1 kinase is a regulator of microtubule-dependent transport in axons
2004
Dystroglycan is required for polarizing the epithelial cells and the oocyte in Drosophila
2002
ER Tubules Mark Sites of Mitochondrial Division
2011 StandoutScience
The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
2005 StandoutScience
Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses
2003
Roles of tau protein in health and disease
2017
Hallmarks of Cancer: The Next Generation
2011 Standout
Creating new fluorescent probes for cell biology
2002 StandoutNobel
Natural Methylamine Osmolytes, Trimethylamine N-Oxide and Betaine, Increase Tau-Induced Polymerization of Microtubules
1998
Increased tau Phosphorylation in Apolipoprotein E4 Transgenic Mice Is Associated with Activation of Extracellular Signal-regulated Kinase
2004
Inducible Expression of Tau Repeat Domain in Cell Models of Tauopathy
2005
Structural modifications of N-arylamide oxadiazoles: Identification of N-arylpiperidine oxadiazoles as potent and selective agonists of CB2
2008
Glycogen Synthase Kinase-3β Phosphorylates Protein Tau and Rescues the Axonopathy in the Central Nervous System of Human Four-repeat Tau Transgenic Mice
2000
PARsing Embryonic Polarity
2000
The Ubiquitin Proteasome System in Neurodegenerative Diseases
2003 StandoutNobel
Role of Microtubules in the Organization of the Golgi Complex
1999
Intercellular junctions and cellular polarity: the PAR–aPKC complex, a conserved core cassette playing fundamental roles in cell polarity
2001
Paullones are potent inhibitors of glycogen synthase kinase‐3β and cyclin‐dependent kinase 5/p25
2000
Going new places using an old MAP: tau, microtubules and human neurodegenerative disease
2001
Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca2+ release channel
2007 StandoutNobel
Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy
2012 Standout
C-terminal ECFP Fusion Impairs Synaptotagmin 1 Function
2004 StandoutNobel
The AMPK signalling pathway coordinates cell growth, autophagy and metabolism
2011 Standout
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
2004 StandoutNobel
Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance
2013
TauGene Mutation K257T Causes a Tauopathy Similar to Pick's Disease
2000
STRING v10: protein–protein interaction networks, integrated over the tree of life
2014 Standout
Tau phosphorylation and aggregation in Alzheimer's disease pathology
2006
The amino terminus of tau inhibits kinesin‐dependent axonal transport: Implications for filament toxicity
2008
Are Tangles as Toxic as They Look?
2011
Stable Expression in Chinese Hamster Ovary Cells of Mutated Tau Genes Causing Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17 (FTDP-17)
1999
LKB1 and AMPK Family Signaling: The Intimate Link Between Cell Polarity and Energy Metabolism
2009
Structural Principles of Tau and the Paired Helical Filaments of Alzheimer’s Disease
2007
Effects of extracellular matrix viscoelasticity on cellular behaviour
2020 StandoutNature
Heads or Tails
2002
An intimate liaison: spatial organization of the endoplasmic reticulum–mitochondria relationship
2010
Mutation-dependent aggregation of tau protein and its selective depletion from the soluble fraction in brain of P301L FTDP-17 patients
2000
Mitochondria: In Sickness and in Health
2012 Standout
Rho GTPases in cell biology
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The SAD-1 Kinase Regulates Presynaptic Vesicle Clustering and Axon Termination
2001
Alzheimer Disease: An Update on Pathobiology and Treatment Strategies
2019 Standout
Cell polarity in the early Caenorhabditis elegans embryo
1999
Controlling reaction specificity in pyridoxal phosphate enzymes
2011
TSC2 Mediates Cellular Energy Response to Control Cell Growth and Survival
2003 Standout
Prominent Axonopathy in the Brain and Spinal Cord of Transgenic Mice Overexpressing Four-Repeat Human tau Protein
1999
Dynein Modifiers in C. elegans: Light Chains Suppress Conditional Heavy Chain Mutants
2007
Functional genomic analysis of C. elegans chromosome I by systematic RNA interference
2000 StandoutNature
Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells
2023 StandoutNobel
The axonal transport of mitochondria
2012
Both the Establishment and the Maintenance of Neuronal Polarity Require Active Mechanisms
2005
LKB1; linking cell structure and tumor suppression
2008
High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis
2014 StandoutNobel
Post-translational modifications of tau protein in Alzheimer’s disease
2004
Alzheimer's Disease
2010 Standout
Asymmetric cell division
1998 Nature
Filamentous nerve cell inclusions in neurodegenerative diseases
1998
Efflux-dependent auxin gradients establish the apical–basal axis of Arabidopsis
2003 StandoutNature
Axonopathy and amyotrophy in mice transgenic for human four-repeat tau protein
2000
The Amyloid State of Proteins in Human Diseases
2012 Standout
Insulin and Insulin-like Growth Factor-1 Regulate Tau Phosphorylation in Cultured Human Neurons
1997
Neuronal polarity: from extracellular signals to intracellular mechanisms
2007
Fibrillogenesis of Tau: Insights from Tau Missense Mutations in FTDP‐17
1999
Tau protein isoforms, phosphorylation and role in neurodegenerative disorders11These authors contributed equally to this work.
2000 Standout
p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development
1999 StandoutNature
AKT/PKB Signaling: Navigating the Network
2017 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Alzheimer-like Changes in Microtubule-associated Protein Tau Induced by Sulfated Glycosaminoglycans
1997
Systematic analysis of genes required for synapse structure and function
2005 StandoutNatureNobel
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
Identification of a novel polymorphism in the promoter region of the tau gene highly associated to progressive supranuclear palsy in humans
1999
Tau pathology in Alzheimer disease and other tauopathies
2004
Tau phosphorylation in Alzheimer's disease: pathogen or protector?
2005
A Putative Src Homology 3 Domain Binding Motif but Not the C-terminal Dystrophin WW Domain Binding Motif Is Required for Dystroglycan Function in Cellular Polarity in Drosophila
2007 StandoutNobel
Tau Filament Formation in Transgenic Mice Expressing P301L Tau
2001
Complexes between the LKB1 tumor suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade
2003
PAR-1 Kinase Plays an Initiator Role in a Temporally Ordered Phosphorylation Process that Confers Tau Toxicity in Drosophila
2004
Cell regulation: determined to signal discrete cooperation
2009
LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR‐1
2004
Nim1-related kinases coordinate cell cycle progression with the organization of the peripheral cytoskeleton in yeast
1999
Single-cell transcriptomic analysis of Alzheimer’s disease
2019 StandoutNature
Jupiter, a newDrosophila protein associated with microtubules
2006
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
Acquired QT interval prolongation and HERG: implications for drug discovery and development
2004
Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival
2007 Standout
Multiple-motor based transport and its regulation by Tau
2006
Fluorine in medicinal chemistry
2007 Standout
Molecular motors implicated in the axonal transport of tau and α-synuclein
2005
Structural Insights into Microtubule Function
2000
Neurodegenerative Tauopathies
2001 Standout
HSP induction mediates selective clearance of tau phosphorylated at proline‐directed Ser/Thr sites but not KXGS (MARK) sites
2006
Golgi twins in late mitosis revealed by genetically encoded tags for live cell imaging and correlated electron microscopy
2006 StandoutNobel
The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
2002 StandoutScience
New Role for hPar-1 Kinases EMK and C-TAK1 in Regulating Localization and Activity of Class IIa Histone Deacetylases
2006
The Protein Kinase Complement of the Human Genome
2002 StandoutScience
Size- and speed-dependent mechanical behavior in living mammalian cytoplasm
2017
Lysosomal activity regulatesCaenorhabditis elegansmitochondrial dynamics through vitamin B12 metabolism
2020 StandoutNobel
Structure, Microtubule Interactions, and Paired Helical Filament Aggregation by Tau Mutants of Frontotemporal Dementias
2000
Tau interaction with microtubules in vivo
2004
A Century of Alzheimer's Disease
2006 StandoutScience
Tau is essential to β-amyloid-induced neurotoxicity
2002
AMP-activated protein kinase (AMPK) is a tau kinase, activated in response to amyloid β-peptide exposure
2011
Inflammation as a central mechanism in Alzheimer's disease
2018 Standout
Rapid dynamics of the microtubule binding of ensconsin in vivo
2001
The Slow Axonal Transport of the Microtubule-Associated Protein Tau and the Transport Rates of Different Isoforms and Mutants in Cultured Neurons
2002
Swimming against the Tide: Mobility of the Microtubule-Associated Protein Tau in Neurons
2007
Human tau filaments induce microtubule and synapse loss in an in vivo model of neurofibrillary degenerative disease
2000
Regulation of Caenorhabditis elegans neuronal polarity by heterochronic genes
2019 StandoutNobel
Vimentin intermediate filaments modulate the motility of mitochondria
2011
LKB1-Dependent Signaling Pathways
2006
Tau Suppression in a Neurodegenerative Mouse Model Improves Memory Function
2005 StandoutScience
Role of Tau Protein in Both Physiological and Pathological Conditions
2004
NuSAP, a novel microtubule-associated protein involved in mitotic spindle organization
2003
Aromatic Sulfonyl Fluorides Covalently Kinetically Stabilize Transthyretin to Prevent Amyloidogenesis while Affording a Fluorescent Conjugate
2013 StandoutNobel
Establishment of Axon-Dendrite Polarity in Developing Neurons
2009
Phosphorylation that Detaches Tau Protein from Microtubules (Ser262, Ser214) Also Protects It against Aggregation into Alzheimer Paired Helical Filaments
1999
Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts
2015 StandoutNobel
Establishment and plasticity of neuronal polarity
1999
An expression screen reveals modulators of class II histone deacetylase phosphorylation
2005
Applications of Palladium-Catalyzed C–N Cross-Coupling Reactions
2016 Standout
Distinct FTDP-17 Missense Mutations in Tau Produce Tau Aggregates and Other Pathological Phenotypes in Transfected CHO Cells
2000
Control of Cardiac Growth by Histone Acetylation/Deacetylation
2006
MAP2 and tau bind longitudinally along the outer ridges of microtubule protofilaments
2002
The Caenorhabditis elegans IMPAS gene, imp-2, is essential for development and is functionally distinct from related presenilins
2004 StandoutNobel
Reducing Endogenous Tau Ameliorates Amyloid ß-Induced Deficits in an Alzheimer's Disease Mouse Model
2007 StandoutScience
Coordinated repression of cell cycle genes by KDM5A and E2F4 during differentiation
2012 StandoutNobel
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
2002
Differential Regulation of Dynein and Kinesin Motor Proteins by Tau
2008 Science
Global Analysis of Protein Activities Using Proteome Chips
2001 StandoutScience
Computational design of a red fluorophore ligase for site-specific protein labeling in living cells
2014 StandoutNobel
Works of Andreas Ebneth being referenced
Phosphorylation of MAP2c and MAP4 by MARK kinases leads to the destabilization of microtubules in cells
1999
MAPs, MARKs and microtubule dynamics
1998
MARK, a Novel Family of Protein Kinases That Phosphorylate Microtubule-Associated Proteins and Trigger Microtubule Disruption
1997
Screening lead compounds for QT interval prolongation
2001
Arylsulfonamide CB2 receptor agonists: SAR and optimization of CB2 selectivity
2008
The Structure of Mammalian Serine Racemase
2010
MARK4 Is a Novel Microtubule-associated Proteins/Microtubule Affinity-regulating Kinase That Binds to the Cellular Microtubule Network and to Centrosomes
2004
HTS techniques to investigate the potential effects of compounds on cardiac ion channels at early-stages of drug discovery.
2003
Tau regulates the attachment/detachment but not the speed of motors in microtubule-dependent transport of single vesicles and organelles
1999
Overexpression of Tau Protein Inhibits Kinesin-dependent Trafficking of Vesicles, Mitochondria, and Endoplasmic Reticulum: Implications for Alzheimer's Disease
1998