Standout Papers
Citation Impact
Citing Papers
Role of LBPA and Alix in Multivesicular Liposome Formation and Endosome Organization
2004 StandoutScienceNobel
Golgi-resident Small GTPase Rab33B Interacts with Atg16L and Modulates Autophagosome Formation
2008
Targeting of Diacylglycerol Degradation to M1 Muscarinic Receptors by ß-Arrestins
2007 StandoutScienceNobel
Distinct Roles of Autophagy in the Heart During Ischemia and Reperfusion
2007
Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms
2018
SNARE Function Analyzed in Synaptobrevin/VAMP Knockout Mice
2001 StandoutScienceNobel
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
α-Synuclein Promotes SNARE-Complex Assembly in Vivo and in Vitro
2010 StandoutScienceNobel
Fusion of Cells by Flipped SNAREs
2003 StandoutScienceNobel
Atg18 Regulates Organelle Morphology and Fab1 Kinase Activity Independent of Its Membrane Recruitment by Phosphatidylinositol 3,5-Bisphosphate
2007
Nutrient-dependent mTORC1 Association with the ULK1–Atg13–FIP200 Complex Required for Autophagy
2009 Standout
TIP47 is a key effector for Rab9 localization
2006
TOR Signaling in Growth and Metabolism
2006 Standout
Dedicated SNARE s and specialized TRIM cargo receptors mediate secretory autophagy
2016
Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures
2018
Current knowledge on exosome biogenesis and release
2017 Standout
Syndecan–syntenin–ALIX regulates the biogenesis of exosomes
2012
Hallmarks of Cancer: The Next Generation
2011 Standout
Exosomes and other extracellular vesicles in host–pathogen interactions
2014
Platelet factor 4–induced T H 1-T reg polarization suppresses antitumor immunity
2024 StandoutScienceNobel
Directional cell movement through tissues is controlled by exosome secretion
2015
ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins
2016
The SILAC Fly Allows for Accurate Protein Quantification in Vivo
2010
Autophagy in cancers including brain tumors: role of MicroRNAs
2020
Cargo recognition and trafficking in selective autophagy
2014
Hrs, a FYVE finger protein localized to early endosomes, is implicated in vesicular traffic and required for ventral folding morphogenesis
1999
Functional architecture of an intracellular membrane t-SNARE
2000 StandoutNatureNobel
Autophagy Suppresses Tumorigenesis through Elimination of p62
2009
Autophagy as a promoter of longevity: insights from model organisms
2018
The role of the Atg1/ULK1 complex in autophagy regulation
2010 Standout
Does Autophagy Contribute To Cell Death?
2005
Autophagosomes form at ER–mitochondria contact sites
2013 StandoutNature
A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates
2009
The Rab5 Effector Rabankyrin-5 Regulates and Coordinates Different Endocytic Mechanisms
2004
ATG12–ATG3 interacts with Alix to promote basal autophagic flux and late endosome function
2015
A Role for Ubiquitin in Selective Autophagy
2009
Inflammation and metabolic disorders
2006 StandoutNature
Mechanisms of regulated unconventional protein secretion
2008
Autophagic Clearance of PolyQ Proteins Mediated by Ubiquitin-Atg8 Adaptors of the Conserved CUET Protein Family
2014
Role and Regulation of Starvation-Induced Autophagy in the Drosophila Fat Body
2004
Autophagy Regulates Programmed Cell Death during the Plant Innate Immune Response
2005
Mechanism and medical implications of mammalian autophagy
2018 Standout
Cargo recognition and degradation by selective autophagy
2018
Structural Clues to Rab GTPase Functional Diversity
2005
HDAC6 controls autophagosome maturation essential for ubiquitin‐selective quality‐control autophagy
2010
Dynamic control of neuroexocytosis by phosphoinositides in health and disease
2010
Derailed endocytosis: an emerging feature of cancer
2008
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Autophagy and signaling: their role in cell survival and cell death
2005
Autophagy Links Inflammasomes to Atherosclerotic Progression
2012
ALFY-Controlled DVL3 Autophagy Regulates Wnt Signaling, Determining Human Brain Size
2016
Macrophage Autophagy Plays a Protective Role in Advanced Atherosclerosis
2012
EGF stimulates annexin 1‐dependent inward vesiculation in a multivesicular endosome subpopulation
2005
Exosomes and Autophagy: Coordinated Mechanisms for the Maintenance of Cellular Fitness
2014
Multiple Cargo Binding Sites on the COPII Subunit Sec24p Ensure Capture of Diverse Membrane Proteins into Transport Vesicles
2003 StandoutNobel
The Role of Phosphoinositide 3-Kinase Lipid Products in Cell Function
1999
The Tetraspanin CD63 Regulates ESCRT-Independent and -Dependent Endosomal Sorting during Melanogenesis
2011
The FYVE Domain of Early Endosome Antigen 1 Is Required for Both Phosphatidylinositol 3-Phosphate and Rab5 Binding
2000
Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease
2008
Atg5 Disassociates the V1V0-ATPase to Promote Exosome Production and Tumor Metastasis Independent of Canonical Macroautophagy
2017
Membrane tethering in intracellular transport
1999
Autophagy is involved in T cell death after binding of HIV-1 envelope proteins to CXCR4
2006
Selective Transport of α-Mannosidase by Autophagic Pathways
2010 StandoutNobel
The Cvt pathway as a model for selective autophagy
2010
Structural Basis for Sorting Mechanism of p62 in Selective Autophagy
2008
Vesicular trafficking and autophagosome formation
2009
Autophagy fights disease through cellular self-digestion
2008 StandoutNature
Oligomeric Complexes Link Rab5 Effectors with NSF and Drive Membrane Fusion via Interactions between EEA1 and Syntaxin 13
1999
Autophagy and amino acid homeostasis are required for chronological longevity in Saccharomyces cerevisiae
2009
Protein Tyrosine Phosphatase Nonreceptor Type 2 Regulates Autophagosome Formation in Human Intestinal Cells
2011
Membrane Domains in the Secretory and Endocytic Pathways
2003
Tetraspanin 6: a pivotal protein of the multiple vesicular body determining exosome release and lysosomal degradation of amyloid precursor protein fragments
2017
Rab proteins as membrane organizers
2001 Standout
Selective Transport of α-Mannosidase by Autophagic Pathways
2010 StandoutNobel
TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways
2009
Peroxisomal Dysfunction in Age-Related Diseases
2017
Two Beclin 1-binding proteins, Atg14L and Rubicon, reciprocally regulate autophagy at different stages
2009
Chromatin modifying protein 1A (Chmp1A) of the endosomal sorting complex required for transport (ESCRT)-III family activates ataxia telangiectasia mutated (ATM) for PanC-1 cell growth inhibition
2011
Role of autophagy in suppression of inflammation and cancer
2010
Antimicrobial Autophagy: A Conserved Innate Immune Response in Drosophila
2013 Standout
The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins
2009 Nature
Unveiling the roles of autophagy in innate and adaptive immunity
2007
Role of autophagy in cancer
2007 Standout
Biogenesis and secretion of exosomes
2014
The Enigmatic Role of C9ORF72 in Autophagy
2017
Atg8‐family interacting motif crucial for selective autophagy
2010 StandoutNobel
Phagosome maturation: going through the acid test
2008
Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice
2010
Direct Induction of Autophagy by Atg1 Inhibits Cell Growth and Induces Apoptotic Cell Death
2007
SNF4Aγ, the Drosophila AMPK γ subunit is required for regulation of developmental and stress-induced autophagy
2008
Can autophagy promote longevity?
2010
Rab GTPases as coordinators of vesicle traffic
2009 Standout
Induction of Autophagy in Axonal Dystrophy and Degeneration
2006
Innate and Adaptive Immunity through Autophagy
2007
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
The Rab5 Effector EEA1 Interacts Directly with Syntaxin-6
1999
Intracellular Toll-like Receptors
2010 StandoutNobel
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice
2006 StandoutNature
Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity
2011
The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress
2007
Secreted Glioblastoma Nanovesicles Contain Intracellular Signaling Proteins and Active Ras Incorporated in a Farnesylation-dependent Manner
2016
Network organization of the human autophagy system
2010 StandoutNature
Shedding light on the cell biology of extracellular vesicles
2018 Standout
Chemical modulators of autophagy as biological probes and potential therapeutics
2010
The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis
1999
Autophagosome formation: core machinery and adaptations
2007 Standout
During autophagy mitochondria elongate, are spared from degradation and sustain cell viability
2011
Mitochondria-Anchored Receptor Atg32 Mediates Degradation of Mitochondria via Selective Autophagy
2009 StandoutNobel
Spermine synthase deficiency causes lysosomal dysfunction and oxidative stress in models of Snyder-Robinson syndrome
2017
Autophagy and Tumor Metabolism
2017
Assaying autophagic activity in transgenic GFP-Lc3 and GFP-Gabarap zebrafish embryos
2009
Subversion of Cellular Autophagosomal Machinery by RNA Viruses
2005
Autophagy, Immunity, and Microbial Adaptations
2009
Membrane protein sequestering by ionic protein–lipid interactions
2011 StandoutNatureNobel
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
The Rab5 effector EEA1 is a core component of endosome docking
1999 Nature
APPL Proteins Link Rab5 to Nuclear Signal Transduction via an Endosomal Compartment
2004
Plasma Membrane Is the Site of Productive HIV-1 Particle Assembly
2006
The Protein Network of HIV Budding
2003
Isolation and Characterization of Rat Liver Amphisomes
1998
Dendritic cells in cancer immunology
2021
Autophagy in the Pathogenesis of Disease
2008 Standout
Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance
2010
Constitutive Autophagy and Nucleophagy during Epidermal Differentiation
2016
The Autoimmunity-Associated Gene CLEC16A Modulates Thymic Epithelial Cell Autophagy and Alters T Cell Selection
2015
Membrane Fusion
2003 StandoutNobel
The ESCRT complexes
2010
Compartmental specificity of cellular membrane fusion encoded in SNARE proteins
2000 StandoutNatureNobel
MX2 is an interferon-induced inhibitor of HIV-1 infection
2013 StandoutNatureNobel
Divalent Rab effectors regulate the sub-compartmental organization and sorting of early endosomes
2002
CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis
2017
Phosphatidylinositol-3-OH kinases are Rab5 effectors
1999
Rab5 regulates motility of early endosomes on microtubules
1999
Exosomes – vesicular carriers for intercellular communication
2009 Standout
Retention of Mitochondria in Mature Human Red Blood Cells as the Result of Autophagy Impairment in Rett Syndrome
2017
Autophagy and human disease: emerging themes
2014
Neural-specific Deletion of FIP200 Leads to Cerebellar Degeneration Caused by Increased Neuronal Death and Axon Degeneration
2009
Self-consumption: the interplay of autophagy and apoptosis
2014 Standout
Regulation of Membrane Trafficking
1999
The Recruitment of Raf-1 to Membranes Is Mediated by Direct Interaction with Phosphatidic Acid and Is Independent of Association with Ras
2000
TAG, a splice variant of the adaptor TRAM, negatively regulates the adaptor MyD88–independent TLR4 pathway
2009
Interactions with LC3 and polyubiquitin chains link nbr1 to autophagic protein turnover
2009
Autophagy Regulates Chromatin Ubiquitination in DNA Damage Response through Elimination of SQSTM1/p62
2016
Growth Factor Regulation of Autophagy and Cell Survival in the Absence of Apoptosis
2005
Nix directly binds to GABARAP: A possible crosstalk between apoptosis and autophagy
2009
Extracellular vesicles shuffling intercellular messages: for good or for bad
2015
Autophagy is essential for mouse sense of balance
2010
Localization of phosphatidylinositol 3-phosphate in yeast and mammalian cells
2000
ATG4B/autophagin-1 regulates intestinal homeostasis and protects mice from experimental colitis
2013
Analysis of ESCRT functions in exosome biogenesis, composition and secretion highlights the heterogeneity of extracellular vesicles
2013
Methods in Mammalian Autophagy Research
2010 Standout
Coordination of Autophagosome–Lysosome Fusion by Atg8 Family Members
2018
Phosphorylation of EEA1 by p38 MAP kinase regulates μ opioid receptor endocytosis
2005
SNAREs and the Secretory Pathway—Lessons from Yeast
1999
Direct interaction of EEA1 with Rab5b
1999
ATM functions at the peroxisome to induce pexophagy in response to ROS
2015
p53 status determines the role of autophagy in pancreatic tumour development
2013 Nature
Autophagy and Aging
2011 Standout
A brief history of autophagy from cell biology to physiology and disease
2018
Congenital disorders of autophagy: an emerging novel class of inborn errors of neuro-metabolism
2015
Regulation of immune responses by extracellular vesicles
2014 Standout
Vac1p coordinates Rab and phosphatidylinositol 3-kinase signaling in Vps45p-dependent vesicle docking/fusion at the endosome
1999
The role of ARF and Rab GTPases in membrane transport
1999
The Role of the Pleckstrin Homology Domain in Membrane Targeting and Activation of Phospholipase Cβ1
2000
Lysosomal Proteolysis and Autophagy Require Presenilin 1 and Are Disrupted by Alzheimer-Related PS1 Mutations
2010
Structural basis of target recognition by Atg8/LC3 during selective autophagy
2008 StandoutNobel
A Lumenal Domain-Dependent Pathway for Sorting to Intralumenal Vesicles of Multivesicular Endosomes Involved in Organelle Morphogenesis
2006
FOXO/4E-BP Signaling in Drosophila Muscles Regulates Organism-wide Proteostasis during Aging
2010
Receptor-mediated selective autophagy degrades the endoplasmic reticulum and the nucleus
2015 StandoutNatureNobel
Delivery of endocytosed membrane proteins to the lysosome
2009
A Picky Eater: Exploring the Mechanisms of Selective Autophagy in Human Pathologies
2007
Autophagy mediates degradation of nuclear lamina
2015 Nature
The Exploitation of Liposomes in the Inhibition of Autophagy to Defeat Drug Resistance
2020
Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney
2010
Unconventional protein secretion in plants: a critical assessment
2015
Selective Subversion of Autophagy Complexes Facilitates Completion of the Brucella Intracellular Cycle
2012
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
The role of autophagy during the early neonatal starvation period
2004 StandoutNatureNobel
Genome-wide analysis of human kinases in clathrin- and caveolae/raft-mediated endocytosis
2005 Nature
Signalome-wide RNAi screen identifies GBA1 as a positive mediator of autophagic cell death
2017
Structure, Exchange Determinants, and Family-Wide Rab Specificity of the Tandem Helical Bundle and Vps9 Domains of Rabex-5
2004
Autophagy: process and function
2007 Standout
Defective downregulation of receptor tyrosine kinases in cancer
2004
Loss of Autophagy Diminishes Pancreatic β Cell Mass and Function with Resultant Hyperglycemia
2008
Exosome Release Is Regulated by a Calcium-dependent Mechanism in K562 Cells
2003
Toward unraveling membrane biogenesis in mammalian autophagy
2008
Overexpression of Atg5 in mice activates autophagy and extends lifespan
2013
Dynamics and diversity in autophagy mechanisms: lessons from yeast
2009 StandoutNobel
Selective Membrane Recruitment of EEA1 Suggests a Role in Directional Transport of Clathrin-coated Vesicles to Early Endosomes
2000
Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4
2007 Standout
Ongoing activation of sphingosine 1-phosphate receptors mediates maturation of exosomal multivesicular endosomes
2013
Reassessment of Exosome Composition
2019 Standout
Genetic aberrations in macroautophagy genes leading to diseases
2018
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferon-β
2008
Distinct Classes of Phosphatidylinositol 3′-Kinases Are Involved in Signaling Pathways That Control Macroautophagy in HT-29 Cells
2000
SARA, a FYVE Domain Protein that Recruits Smad2 to the TGFβ Receptor
1998
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
The Complex Ultrastructure of the Endolysosomal System
2014
Signalling through phosphoinositide 3-kinases: the lipids take centre stage
1999
Autophagy in the liver: functions in health and disease
2017
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1
2010 Standout
Phosphoinositide signaling and the regulation of membrane trafficking in yeast
2000
Signaling, Polyubiquitination, Trafficking, and Inclusions: Sequestosome 1/p62′s Role in Neurodegenerative Disease
2006
Membrane fusion
2008 StandoutNobel
Parkin Modulates Endosomal Organization and Function of the Endo-Lysosomal Pathway
2016
The endocytic pathway: a mosaic of domains
2001
Autophagy-related Protein 8 (Atg8) Family Interacting Motif in Atg3 Mediates the Atg3-Atg8 Interaction and Is Crucial for the Cytoplasm-to-Vacuole Targeting Pathway
2010 StandoutNobel
SEPA-1 Mediates the Specific Recognition and Degradation of P Granule Components by Autophagy in C. elegans
2009
Autophagy activators suppress cystogenesis in an autosomal dominant polycystic kidney disease model
2016
Autophagy Inhibition Compromises Degradation of Ubiquitin-Proteasome Pathway Substrates
2009
Deletion of the Huntingtin Polyglutamine Stretch Enhances Neuronal Autophagy and Longevity in Mice
2010
Extracellular Vesicles in Cancer: Exosomes, Microvesicles and the Emerging Role of Large Oncosomes
2015
MTMR3 risk allele enhances innate receptor-induced signaling and cytokines by decreasing autophagy and increasing caspase-1 activation
2015
Rabenosyn-5, a Novel Rab5 Effector, Is Complexed with Hvps45 and Recruited to Endosomes through a Fyve Finger Domain
2000
FENS-1 and DFCP1 are FYVE domain-containing proteins with distinct functions in the endosomal and Golgi compartments
2001
Extracellular vesicles: Exosomes, microvesicles, and friends
2013 Standout
mTOR's role in ageing: protein synthesis or autophagy?
2009
Mechanisms and context underlying the role of autophagy in cancer metastasis
2018
Small GTP-Binding Proteins
2001 Standout
Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster
2010
An Atg1/Atg13 Complex with Multiple Roles in TOR-mediated Autophagy Regulation
2009
Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
2016 Standout
TRIM17 contributes to autophagy of midbodies while actively sparing other targets from degradation
2016
Combinational Soluble N-Ethylmaleimide-sensitive Factor Attachment Protein Receptor Proteins VAMP8 and Vti1b Mediate Fusion of Antimicrobial and Canonical Autophagosomes with Lysosomes
2010
Role of Drosophila Rab5 during endosomal trafficking at the synapse and evoked neurotransmitter release
2003
Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1
2016
Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration
2007
EEA1, a Tethering Protein of the Early Sorting Endosome, Shows a Polarized Distribution in Hippocampal Neurons, Epithelial Cells, and Fibroblasts
2000
Distinct Membrane Domains on Endosomes in the Recycling Pathway Visualized by Multicolor Imaging of Rab4, Rab5, and Rab11
2000
MHC class II‐associated proteins in B‐cell exosomes and potential functional implications for exosome biogenesis
2010
PtdIns-specific MPR Pathway Association of a Novel WD40 Repeat Protein, WIPI49
2004
Organellophagy: Eliminating cellular building blocks via selective autophagy
2014
Yeast vacuoles and membrane fusion pathways
2002
Calpain is required for macroautophagy in mammalian cells
2006
The Phosphatidylinositol 3-Phosphate Binding Protein Vac1p Interacts with a Rab GTPase and a Sec1p Homologue to Facilitate Vesicle-mediated Vacuolar Protein Sorting
1999
Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein
2012
ATG Systems from the Protein Structural Point of View
2009 StandoutNobel
Focus on Extracellular Vesicles: Introducing the Next Small Big Thing
2016
FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells
2008
Regulation Mechanisms and Signaling Pathways of Autophagy
2009 Standout
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes
2008 Standout
Relationships between EEA1 binding partners and their role in endosome fusion
2001
Autophagy and the endo/exosomal pathways in health and disease
2016
Autophagy During Cardiac Stress: Joys and Frustrations of Autophagy
2010
Autophagy controls mesenchymal stem cell properties and senescence during bone aging
2017
Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation
2014
Coordination of membrane events during autophagy by multiple class III PI3-kinase complexes
2009
Progranulin deficiency causes impairment of autophagy and TDP-43 accumulation
2017
TRIM-mediated precision autophagy targets cytoplasmic regulators of innate immunity
2015
Functional specificity of the mammalian Beclin-Vps34 PI 3-kinase complex in macroautophagy versus endocytosis and lysosomal enzyme trafficking
2006
How to Live Long and Prosper: Autophagy, Mitochondria, and Aging
2008
Rab1 Recruitment of p115 into a cis-SNARE Complex: Programming Budding COPII Vesicles for Fusion
2000 Science
The N-terminus and Phe52 residue of LC3 recruit p62/SQSTM1 into autophagosomes
2008
FYVE-finger proteins – effectors of an inositol lipid
1999
Membrane Fusion and Exocytosis
1999 StandoutNobel
Structural insights into the recognition of phosphorylated FUNDC1 by LC3B in mitophagy
2016
Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG
2008
Drosophila Melted Modulates FOXO and TOR Activity
2005
Atg19 Mediates a Dual Interaction Cargo Sorting Mechanism in Selective Autophagy
2006
Bruchpilot Promotes Active Zone Assembly, Ca 2+ Channel Clustering, and Vesicle Release
2006 StandoutScienceNobel
Intermittent fasting preserves beta-cell mass in obesity-induced diabetes via the autophagy-lysosome pathway
2017
Membrane Recognition and Targeting by Lipid-Binding Domains
2003
Coordinated regulation of AP2 uncoating from clathrin-coated vesicles by rab5 and hRME-6
2008
Autophagy pathway: Cellular and molecular mechanisms
2017 Standout
SARA, a FYVE domain protein, affects Rab5-mediated endocytosis
2002
Regulation of autophagy by mTOR-dependent and mTOR-independent pathways: autophagy dysfunction in neurodegenerative diseases and therapeutic application of autophagy enhancers
2013
Hrs‐ and CD63 ‐Dependent Competing Mechanisms Make Different Sized Endosomal Intraluminal Vesicles
2013
Distinct Roles for the p110α and hVPS34 Phosphatidylinositol 3′-Kinases in Vesicular Trafficking, Regulation of the Actin Cytoskeleton, and Mitogenesis
1998
Regulation of innate immune responses by autophagy-related proteins
2010
Biochemical analysis of distinct Rab5- and Rab11-positive endosomes along the transferrin pathway
1999
Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles
2014 Standout
An Atg4B Mutant Hampers the Lipidation of LC3 Paralogues and Causes Defects in Autophagosome Closure
2008
Protein Turnover Via Autophagy: Implications for Metabolism
2007
Three v-SNAREs and Two t-SNAREs, Present in a Pentameric cis-SNARE Complex on Isolated Vacuoles, Are Essential for Homotypic Fusion
1999
The R740S mutation in the V‐ATP ase a3 subunit results in osteoclast apoptosis and defective early‐stage autophagy
2013
Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy
2009
Nix is a selective autophagy receptor for mitochondrial clearance
2009
A FYVE-finger-containing protein, Rabip4, is a Rab4 effector involved in early endosomal traffic
2001
Yeast Homotypic Vacuole Fusion: A Window on Organelle Trafficking Mechanisms
2000
Essential role of Ca2+/Calmodulin in Early Endosome Antigen-1 Localization
2003
An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway
2005
Unconventional Secretion, Unconventional Solutions
2013 StandoutScienceNobel
The WD40 and FYVE domain containing protein 2 defines a class of early endosomes necessary for endocytosis
2006 StandoutNobel
The endosome fusion regulator early-endosomal autoantigen 1 (EEA1) is a dimer
1999
A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy
2008
The Double-Edged Sword of Autophagy Modulation in Cancer
2009
The position of lysosomes within the cell determines their luminal pH
2016
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
NUFIP1 is a ribosome receptor for starvation-induced ribophagy
2018 Science
Regulation of Mammalian Autophagy in Physiology and Pathophysiology
2010 Standout
Organizing Polarized Delivery of Exosomes at Synapses
2015
Works of Andreas Brech being referenced
p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
2005 Standout
The Adaptor Protein p62/SQSTM1 Targets Invading Bacteria to the Autophagy Pathway
2009
Effects of inhibitors of the vacuolar proton pump on hepatic heterophagy and autophagy
2001
Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila
2008
The Ether Lipid Precursor Hexadecylglycerol Stimulates the Release and Changes the Composition of Exosomes Derived from PC-3 Cells
2014
Cell death duringDrosophila melanogasterearly oogenesis is mediated through autophagy
2009
Expression of B-Cell Surface Antigens in Subpopulations of Exosomes Released From B-Cell Lymphoma Cells
2014
p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy
2007 Standout
PIKfyve inhibition increases exosome release and induces secretory autophagy
2016
A dual function for Deep orange in programmed autophagy in the Drosophila melanogaster fat body
2006
Vps22/EAP30 in ESCRT‐II Mediates Endosomal Sorting of Growth Factor and Chemokine Receptors Destined for Lysosomal Degradation
2007
Multivesicular Endosome Biogenesis in the Absence of ESCRTs
2009
The Selective Macroautophagic Degradation of Aggregated Proteins Requires the PI3P-Binding Protein Alfy
2010
The PI 3-kinase regulator Vps15 is required for autophagic clearance of protein aggregates
2008
Endocytic pathways regulate Toll‐like receptor 4 signaling and link innate and adaptive immunity
2006
Profiling of microRNAs in exosomes released from PC-3 prostate cancer cells
2012
Microenvironmental autophagy promotes tumour growth
2017 Nature
Chapter 12 Monitoring Autophagic Degradation of p62/SQSTM1
2009
Ubiquitination of α5β1 Integrin Controls Fibroblast Migration through Lysosomal Degradation of Fibronectin-Integrin Complexes
2010
ESCRTs and Fab1 Regulate Distinct Steps of Autophagy
2007
p62/SQSTM1 and ALFY interact to facilitate the formation of p62 bodies/ALIS and their degradation by autophagy
2010
NBR1 acts as an autophagy receptor for peroxisomes
2012
Programmed Autophagy in the Drosophila Fat Body Is Induced by Ecdysone through Regulation of the PI3K Pathway
2004
ESCRT proteins in physiology and disease
2008
EEA1 links PI(3)K function to Rab5 regulation of endosome fusion
1998 Nature
Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes
2003
Fab1 Phosphatidylinositol 3-Phosphate 5-Kinase Controls Trafficking but Not Silencing of Endocytosed Receptors
2006
The ESCRT-III Subunit hVps24 Is Required for Degradation but Not Silencing of the Epidermal Growth Factor Receptor
2006
Regulation of Early Endosomal Entry by theDrosophilaTumor Suppressors Rabenosyn and Vps45
2008
Functional multivesicular bodies are required for autophagic clearance of protein aggregates associated with neurodegenerative disease
2007
Phosphoinositide 3-kinase regulates maturation of lysosomes in rat hepatocytes
2003
Alix regulates cortical actin and the spatial distribution of endosomes
2005
Ultrastructural characterization of giant endosomes induced by GTPase-deficient Rab5
2009
FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end–directed vesicle transport
2010
Ref(2)P, the Drosophila melanogaster homologue of mammalian p62, is required for the formation of protein aggregates in adult brain
2008
Inhibition of asialoglycoprotein endocytosis and degradation in rat hepatocytes by protein phosphatase inhibitors
1995
Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes
2004
Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis
2010
RILP is required for the proper morphology and function of late endosomes
2007